Effects of sacubitril/valsartan in patients with a systemic right ventricle: early evidence of exercise tolerance and systolic function improvement Article Swipe
Flavia Fusco
,
Assunta Merola
,
Giancarlo Scognamiglio
,
Michela Palma
,
Anna Correra
,
Rosaria Barracano
,
Nunzia Borrelli
,
N Grimaldi
,
C Spinelli Barrile
,
N Puzone
,
Giovanni Domenico Ciriello
,
Diego Colonna
,
Emanuele Romeo
,
Berardo Sarubbi
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1093/eurheartj/ehab724.1877
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1093/eurheartj/ehab724.1877
Background Sacubitril/valsartan has been shown to reduce mortality and morbidity inpatients with heart failure and reduced systolic function. However, the effects of this novel association in patients with congenital heart disease and a systemic right ventricle (sRV) have not been investigated yet. Purpose We aimed to assess tolerability and efficacy of sacubitril/valsartan in patients with a sRV Methods From September 2020 to March 2021, 38 patients with congenitally corrected transposition of the great arteries or transposition of the great arteries after Senning or Mustard repair were prospectively enrolled. Inclusion criteria were: age ≥18 years, optimal medical therapy including ACEi/ARB for at least 6 months and EF of the sRV ≤40%. Patients with univentricular physiology, systolic blood pressure (SBP) <90mmHg, glomerular filtration rate (GFR) <30ml/min or K >5.5mEq/L were excluded. RV systolic function was assessed on echocardiography using a multiparametric evaluation. The study protocol contemplates serial assessments at 1, 3, 6 and 12 months after treatment initiation. Results Up to March 31th, 23 patients completed 1-month and 15 completed 3-month assessment after treatment initiation. Baseline patients' characteristics are summarized in table 1. The medication dose was up-titrated to the highest tolerated dose during follow-up. During early follow-up, no major adverse events were reported. Treatment did not impact significantly on the values of serum potassium (basal K+ 4.4 [4.2–4.6] mEq/L, K+ at 3 months 4.4 [4.3–4.6] mEq/L, p=0.7) and GFR (basal GFR 113.9±35ml/min, GFR at 3 months 107.8±21 ml/min, p=0.7). Although SBP did not change significantly (114±12 vs 113.9±19 mmHg at 1-month and 117.3±12 mmHg at 3 months; p=0.9 for both), 2 (5%) patients ceased the treatment due to symptomatic hypotension during the first month of treatment. There was no significant change in the NYHA class. However, the 6-minute walking distance increased significantly after 3 months (365±120 vs 498.3±71 min; p=0.01). Furthermore, while traditional echocardiographic parameters of RV systolic function (TAPSE, s wave and FAC) did not change significantly, RV global longitudinal strain (GLS) and RV free wall GLS demonstrated subclinical improvement in right ventricular systolic function (table 2). Conclusions Our short-term results from an ongoing prospective study showed that sacubitril/valsartan is well tolerated in patients with a sRV with early evidence of improvement in exercise tolerance and sRV systolic function. Longer follow-up is warranted to confirm these data. Funding Acknowledgement Type of funding sources: None. Table 1Table 2
Related Topics
Concepts
Medicine
Great arteries
Sacubitril
Tolerability
Cardiology
Internal medicine
Heart failure
Blood pressure
Ventricle
Renal function
Valsartan
Sacubitril, Valsartan
Adverse effect
Transposition of the great vessels
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/eurheartj/ehab724.1877
- https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.1877/41057104/ehab724.1877.pdf
- OA Status
- bronze
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3208050198
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3208050198Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/eurheartj/ehab724.1877Digital Object Identifier
- Title
-
Effects of sacubitril/valsartan in patients with a systemic right ventricle: early evidence of exercise tolerance and systolic function improvementWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-10-01Full publication date if available
- Authors
-
Flavia Fusco, Assunta Merola, Giancarlo Scognamiglio, Michela Palma, Anna Correra, Rosaria Barracano, Nunzia Borrelli, N Grimaldi, C Spinelli Barrile, N Puzone, Giovanni Domenico Ciriello, Diego Colonna, Emanuele Romeo, Berardo SarubbiList of authors in order
- Landing page
-
https://doi.org/10.1093/eurheartj/ehab724.1877Publisher landing page
- PDF URL
-
https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.1877/41057104/ehab724.1877.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.1877/41057104/ehab724.1877.pdfDirect OA link when available
- Concepts
-
Medicine, Great arteries, Sacubitril, Tolerability, Cardiology, Internal medicine, Heart failure, Blood pressure, Ventricle, Renal function, Valsartan, Sacubitril, Valsartan, Adverse effect, Transposition of the great vesselsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3208050198 |
|---|---|
| doi | https://doi.org/10.1093/eurheartj/ehab724.1877 |
| ids.doi | https://doi.org/10.1093/eurheartj/ehab724.1877 |
| ids.mag | 3208050198 |
| ids.openalex | https://openalex.org/W3208050198 |
| fwci | 0.0 |
| type | article |
| title | Effects of sacubitril/valsartan in patients with a systemic right ventricle: early evidence of exercise tolerance and systolic function improvement |
| biblio.issue | Supplement_1 |
| biblio.volume | 42 |
| biblio.last_page | |
| biblio.first_page | |
| topics[0].id | https://openalex.org/T10300 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9983999729156494 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2713 |
| topics[0].subfield.display_name | Epidemiology |
| topics[0].display_name | Congenital Heart Disease Studies |
| topics[1].id | https://openalex.org/T10198 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9983000159263611 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2705 |
| topics[1].subfield.display_name | Cardiology and Cardiovascular Medicine |
| topics[1].display_name | Heart Failure Treatment and Management |
| topics[2].id | https://openalex.org/T10598 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9789999723434448 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2705 |
| topics[2].subfield.display_name | Cardiology and Cardiovascular Medicine |
| topics[2].display_name | Cardiac pacing and defibrillation studies |
| is_xpac | False |
| apc_list.value | 4238 |
| apc_list.currency | EUR |
| apc_list.value_usd | 4570 |
| apc_paid | |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9668688774108887 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C2776064143 |
| concepts[1].level | 3 |
| concepts[1].score | 0.6377812623977661 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q5600329 |
| concepts[1].display_name | Great arteries |
| concepts[2].id | https://openalex.org/C2776754050 |
| concepts[2].level | 4 |
| concepts[2].score | 0.611240565776825 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q17811448 |
| concepts[2].display_name | Sacubitril |
| concepts[3].id | https://openalex.org/C2778375690 |
| concepts[3].level | 3 |
| concepts[3].score | 0.6091218590736389 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q7814214 |
| concepts[3].display_name | Tolerability |
| concepts[4].id | https://openalex.org/C164705383 |
| concepts[4].level | 1 |
| concepts[4].score | 0.6083434224128723 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q10379 |
| concepts[4].display_name | Cardiology |
| concepts[5].id | https://openalex.org/C126322002 |
| concepts[5].level | 1 |
| concepts[5].score | 0.5971977710723877 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[5].display_name | Internal medicine |
| concepts[6].id | https://openalex.org/C2778198053 |
| concepts[6].level | 2 |
| concepts[6].score | 0.5896012187004089 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q181754 |
| concepts[6].display_name | Heart failure |
| concepts[7].id | https://openalex.org/C84393581 |
| concepts[7].level | 2 |
| concepts[7].score | 0.5646761655807495 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q82642 |
| concepts[7].display_name | Blood pressure |
| concepts[8].id | https://openalex.org/C2778921608 |
| concepts[8].level | 2 |
| concepts[8].score | 0.5531896948814392 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q2002035 |
| concepts[8].display_name | Ventricle |
| concepts[9].id | https://openalex.org/C159641895 |
| concepts[9].level | 2 |
| concepts[9].score | 0.5205546617507935 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q108377937 |
| concepts[9].display_name | Renal function |
| concepts[10].id | https://openalex.org/C2777387769 |
| concepts[10].level | 3 |
| concepts[10].score | 0.5147724151611328 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q155472 |
| concepts[10].display_name | Valsartan |
| concepts[11].id | https://openalex.org/C2775999527 |
| concepts[11].level | 4 |
| concepts[11].score | 0.48883360624313354 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q17811448 |
| concepts[11].display_name | Sacubitril, Valsartan |
| concepts[12].id | https://openalex.org/C197934379 |
| concepts[12].level | 2 |
| concepts[12].score | 0.48375511169433594 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q2047938 |
| concepts[12].display_name | Adverse effect |
| concepts[13].id | https://openalex.org/C2778200330 |
| concepts[13].level | 4 |
| concepts[13].score | 0.47599685192108154 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q1758730 |
| concepts[13].display_name | Transposition of the great vessels |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.9668688774108887 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/great-arteries |
| keywords[1].score | 0.6377812623977661 |
| keywords[1].display_name | Great arteries |
| keywords[2].id | https://openalex.org/keywords/sacubitril |
| keywords[2].score | 0.611240565776825 |
| keywords[2].display_name | Sacubitril |
| keywords[3].id | https://openalex.org/keywords/tolerability |
| keywords[3].score | 0.6091218590736389 |
| keywords[3].display_name | Tolerability |
| keywords[4].id | https://openalex.org/keywords/cardiology |
| keywords[4].score | 0.6083434224128723 |
| keywords[4].display_name | Cardiology |
| keywords[5].id | https://openalex.org/keywords/internal-medicine |
| keywords[5].score | 0.5971977710723877 |
| keywords[5].display_name | Internal medicine |
| keywords[6].id | https://openalex.org/keywords/heart-failure |
| keywords[6].score | 0.5896012187004089 |
| keywords[6].display_name | Heart failure |
| keywords[7].id | https://openalex.org/keywords/blood-pressure |
| keywords[7].score | 0.5646761655807495 |
| keywords[7].display_name | Blood pressure |
| keywords[8].id | https://openalex.org/keywords/ventricle |
| keywords[8].score | 0.5531896948814392 |
| keywords[8].display_name | Ventricle |
| keywords[9].id | https://openalex.org/keywords/renal-function |
| keywords[9].score | 0.5205546617507935 |
| keywords[9].display_name | Renal function |
| keywords[10].id | https://openalex.org/keywords/valsartan |
| keywords[10].score | 0.5147724151611328 |
| keywords[10].display_name | Valsartan |
| keywords[11].id | https://openalex.org/keywords/sacubitril-valsartan |
| keywords[11].score | 0.48883360624313354 |
| keywords[11].display_name | Sacubitril, Valsartan |
| keywords[12].id | https://openalex.org/keywords/adverse-effect |
| keywords[12].score | 0.48375511169433594 |
| keywords[12].display_name | Adverse effect |
| keywords[13].id | https://openalex.org/keywords/transposition-of-the-great-vessels |
| keywords[13].score | 0.47599685192108154 |
| keywords[13].display_name | Transposition of the great vessels |
| language | en |
| locations[0].id | doi:10.1093/eurheartj/ehab724.1877 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S181568219 |
| locations[0].source.issn | 0195-668X, 1522-9645 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0195-668X |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | European Heart Journal |
| locations[0].source.host_organization | https://openalex.org/P4310311648 |
| locations[0].source.host_organization_name | Oxford University Press |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310311648 |
| locations[0].license | |
| locations[0].pdf_url | https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.1877/41057104/ehab724.1877.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | European Heart Journal |
| locations[0].landing_page_url | https://doi.org/10.1093/eurheartj/ehab724.1877 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5058480344 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-9061-7834 |
| authorships[0].author.display_name | Flavia Fusco |
| authorships[0].countries | IT |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[0].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[0].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[0].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[0].institutions[0].country_code | IT |
| authorships[0].institutions[0].display_name | Ospedale Monaldi |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | F Fusco |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[1].author.id | https://openalex.org/A5014896568 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-2978-9696 |
| authorships[1].author.display_name | Assunta Merola |
| authorships[1].countries | IT |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[1].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[1].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[1].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[1].institutions[0].country_code | IT |
| authorships[1].institutions[0].display_name | Ospedale Monaldi |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | A Merola |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[2].author.id | https://openalex.org/A5001228729 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-2279-4265 |
| authorships[2].author.display_name | Giancarlo Scognamiglio |
| authorships[2].countries | IT |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[2].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[2].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[2].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[2].institutions[0].country_code | IT |
| authorships[2].institutions[0].display_name | Ospedale Monaldi |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | G Scognamiglio |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[3].author.id | https://openalex.org/A5002432747 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-3954-8036 |
| authorships[3].author.display_name | Michela Palma |
| authorships[3].countries | IT |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[3].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[3].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[3].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[3].institutions[0].country_code | IT |
| authorships[3].institutions[0].display_name | Ospedale Monaldi |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | M Palma |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[4].author.id | https://openalex.org/A5060129844 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-8733-7436 |
| authorships[4].author.display_name | Anna Correra |
| authorships[4].countries | IT |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[4].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[4].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[4].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[4].institutions[0].country_code | IT |
| authorships[4].institutions[0].display_name | Ospedale Monaldi |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | A Correra |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[5].author.id | https://openalex.org/A5061666641 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-6380-073X |
| authorships[5].author.display_name | Rosaria Barracano |
| authorships[5].countries | IT |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[5].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[5].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[5].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[5].institutions[0].country_code | IT |
| authorships[5].institutions[0].display_name | Ospedale Monaldi |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | R Barracano |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[6].author.id | https://openalex.org/A5023257372 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-4283-7824 |
| authorships[6].author.display_name | Nunzia Borrelli |
| authorships[6].countries | IT |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[6].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[6].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[6].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[6].institutions[0].type | healthcare |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[6].institutions[0].country_code | IT |
| authorships[6].institutions[0].display_name | Ospedale Monaldi |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | N Borrelli |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[7].author.id | https://openalex.org/A5060083685 |
| authorships[7].author.orcid | https://orcid.org/0000-0001-5908-178X |
| authorships[7].author.display_name | N Grimaldi |
| authorships[7].countries | IT |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[7].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[7].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[7].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[7].institutions[0].country_code | IT |
| authorships[7].institutions[0].display_name | Ospedale Monaldi |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | N Grimaldi |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[8].author.id | https://openalex.org/A5068364570 |
| authorships[8].author.orcid | |
| authorships[8].author.display_name | C Spinelli Barrile |
| authorships[8].countries | IT |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[8].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[8].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[8].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[8].institutions[0].country_code | IT |
| authorships[8].institutions[0].display_name | Ospedale Monaldi |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | C Spinelli Barrile |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[9].author.id | https://openalex.org/A5083633592 |
| authorships[9].author.orcid | |
| authorships[9].author.display_name | N Puzone |
| authorships[9].countries | IT |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[9].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[9].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[9].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[9].institutions[0].type | healthcare |
| authorships[9].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[9].institutions[0].country_code | IT |
| authorships[9].institutions[0].display_name | Ospedale Monaldi |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | N Puzone |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[10].author.id | https://openalex.org/A5056959992 |
| authorships[10].author.orcid | https://orcid.org/0000-0001-6115-9435 |
| authorships[10].author.display_name | Giovanni Domenico Ciriello |
| authorships[10].countries | IT |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[10].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[10].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[10].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[10].institutions[0].type | healthcare |
| authorships[10].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[10].institutions[0].country_code | IT |
| authorships[10].institutions[0].display_name | Ospedale Monaldi |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | G D Ciriello |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[11].author.id | https://openalex.org/A5006694254 |
| authorships[11].author.orcid | https://orcid.org/0000-0001-6717-1953 |
| authorships[11].author.display_name | Diego Colonna |
| authorships[11].countries | IT |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[11].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[11].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[11].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[11].institutions[0].type | healthcare |
| authorships[11].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[11].institutions[0].country_code | IT |
| authorships[11].institutions[0].display_name | Ospedale Monaldi |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | D Colonna |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[12].author.id | https://openalex.org/A5054988472 |
| authorships[12].author.orcid | https://orcid.org/0000-0003-0458-8609 |
| authorships[12].author.display_name | Emanuele Romeo |
| authorships[12].countries | IT |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[12].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[12].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[12].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[12].institutions[0].type | healthcare |
| authorships[12].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[12].institutions[0].country_code | IT |
| authorships[12].institutions[0].display_name | Ospedale Monaldi |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | E Romeo |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[13].author.id | https://openalex.org/A5076951922 |
| authorships[13].author.orcid | https://orcid.org/0000-0001-9941-8500 |
| authorships[13].author.display_name | Berardo Sarubbi |
| authorships[13].countries | IT |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I4210140815 |
| authorships[13].affiliations[0].raw_affiliation_string | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| authorships[13].institutions[0].id | https://openalex.org/I4210140815 |
| authorships[13].institutions[0].ror | https://ror.org/0560hqd63 |
| authorships[13].institutions[0].type | healthcare |
| authorships[13].institutions[0].lineage | https://openalex.org/I4210140815 |
| authorships[13].institutions[0].country_code | IT |
| authorships[13].institutions[0].display_name | Ospedale Monaldi |
| authorships[13].author_position | last |
| authorships[13].raw_author_name | B Sarubbi |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | AO dei Colli-Monaldi Hospital, Adult Congenital Heart Disease Unit, Naples, Italy |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.1877/41057104/ehab724.1877.pdf |
| open_access.oa_status | bronze |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Effects of sacubitril/valsartan in patients with a systemic right ventricle: early evidence of exercise tolerance and systolic function improvement |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10300 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9983999729156494 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2713 |
| primary_topic.subfield.display_name | Epidemiology |
| primary_topic.display_name | Congenital Heart Disease Studies |
| related_works | https://openalex.org/W3188325112, https://openalex.org/W2776335933, https://openalex.org/W3195938057, https://openalex.org/W2945205947, https://openalex.org/W4235888460, https://openalex.org/W2904992990, https://openalex.org/W2914028752, https://openalex.org/W4323356027, https://openalex.org/W2758753471, https://openalex.org/W3208470283 |
| cited_by_count | 0 |
| locations_count | 1 |
| best_oa_location.id | doi:10.1093/eurheartj/ehab724.1877 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S181568219 |
| best_oa_location.source.issn | 0195-668X, 1522-9645 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0195-668X |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | European Heart Journal |
| best_oa_location.source.host_organization | https://openalex.org/P4310311648 |
| best_oa_location.source.host_organization_name | Oxford University Press |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310311648 |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.1877/41057104/ehab724.1877.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | European Heart Journal |
| best_oa_location.landing_page_url | https://doi.org/10.1093/eurheartj/ehab724.1877 |
| primary_location.id | doi:10.1093/eurheartj/ehab724.1877 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S181568219 |
| primary_location.source.issn | 0195-668X, 1522-9645 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0195-668X |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | European Heart Journal |
| primary_location.source.host_organization | https://openalex.org/P4310311648 |
| primary_location.source.host_organization_name | Oxford University Press |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310311648 |
| primary_location.license | |
| primary_location.pdf_url | https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.1877/41057104/ehab724.1877.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | European Heart Journal |
| primary_location.landing_page_url | https://doi.org/10.1093/eurheartj/ehab724.1877 |
| publication_date | 2021-10-01 |
| publication_year | 2021 |
| referenced_works_count | 0 |
| abstract_inverted_index.2 | 260, 387 |
| abstract_inverted_index.3 | 221, 234, 255, 293 |
| abstract_inverted_index.6 | 103, 150 |
| abstract_inverted_index.K | 126 |
| abstract_inverted_index.a | 33, 56, 138, 356 |
| abstract_inverted_index.s | 310 |
| abstract_inverted_index.1, | 148 |
| abstract_inverted_index.1. | 181 |
| abstract_inverted_index.12 | 152 |
| abstract_inverted_index.15 | 167 |
| abstract_inverted_index.23 | 162 |
| abstract_inverted_index.3, | 149 |
| abstract_inverted_index.38 | 65 |
| abstract_inverted_index.EF | 106 |
| abstract_inverted_index.K+ | 215, 219 |
| abstract_inverted_index.RV | 130, 306, 318, 324 |
| abstract_inverted_index.Up | 158 |
| abstract_inverted_index.We | 44 |
| abstract_inverted_index.an | 343 |
| abstract_inverted_index.at | 101, 147, 220, 233, 249, 254 |
| abstract_inverted_index.in | 26, 53, 179, 281, 331, 353, 363 |
| abstract_inverted_index.is | 350, 372 |
| abstract_inverted_index.no | 197, 278 |
| abstract_inverted_index.of | 22, 51, 71, 77, 107, 211, 274, 305, 361, 381 |
| abstract_inverted_index.on | 135, 208 |
| abstract_inverted_index.or | 75, 83, 125 |
| abstract_inverted_index.to | 6, 46, 62, 159, 187, 267, 374 |
| abstract_inverted_index.vs | 246, 296 |
| abstract_inverted_index.2). | 337 |
| abstract_inverted_index.4.4 | 216, 223 |
| abstract_inverted_index.GFR | 228, 230, 232 |
| abstract_inverted_index.GLS | 327 |
| abstract_inverted_index.Our | 339 |
| abstract_inverted_index.SBP | 240 |
| abstract_inverted_index.The | 141, 182 |
| abstract_inverted_index.age | 92 |
| abstract_inverted_index.and | 9, 15, 32, 49, 105, 151, 166, 227, 251, 312, 323, 366 |
| abstract_inverted_index.are | 177 |
| abstract_inverted_index.did | 204, 241, 314 |
| abstract_inverted_index.due | 266 |
| abstract_inverted_index.for | 100, 258 |
| abstract_inverted_index.has | 3 |
| abstract_inverted_index.not | 39, 205, 242, 315 |
| abstract_inverted_index.sRV | 57, 109, 357, 367 |
| abstract_inverted_index.the | 20, 72, 78, 108, 188, 209, 264, 271, 282, 286 |
| abstract_inverted_index.was | 133, 185, 277 |
| abstract_inverted_index.(5%) | 261 |
| abstract_inverted_index.2020 | 61 |
| abstract_inverted_index.FAC) | 313 |
| abstract_inverted_index.From | 59 |
| abstract_inverted_index.NYHA | 283 |
| abstract_inverted_index.Type | 380 |
| abstract_inverted_index.been | 4, 40 |
| abstract_inverted_index.dose | 184, 191 |
| abstract_inverted_index.free | 325 |
| abstract_inverted_index.from | 342 |
| abstract_inverted_index.have | 38 |
| abstract_inverted_index.min; | 298 |
| abstract_inverted_index.mmHg | 248, 253 |
| abstract_inverted_index.rate | 122 |
| abstract_inverted_index.that | 348 |
| abstract_inverted_index.this | 23 |
| abstract_inverted_index.wall | 326 |
| abstract_inverted_index.wave | 311 |
| abstract_inverted_index.well | 351 |
| abstract_inverted_index.were | 86, 128, 201 |
| abstract_inverted_index.with | 12, 28, 55, 67, 112, 355, 358 |
| abstract_inverted_index.yet. | 42 |
| abstract_inverted_index.(GFR) | 123 |
| abstract_inverted_index.(GLS) | 322 |
| abstract_inverted_index.(SBP) | 118 |
| abstract_inverted_index.(sRV) | 37 |
| abstract_inverted_index.2021, | 64 |
| abstract_inverted_index.31th, | 161 |
| abstract_inverted_index.March | 63, 160 |
| abstract_inverted_index.None. | 384 |
| abstract_inverted_index.Table | 385 |
| abstract_inverted_index.There | 276 |
| abstract_inverted_index.after | 81, 154, 171, 292 |
| abstract_inverted_index.aimed | 45 |
| abstract_inverted_index.blood | 116 |
| abstract_inverted_index.data. | 377 |
| abstract_inverted_index.early | 195, 359 |
| abstract_inverted_index.first | 272 |
| abstract_inverted_index.great | 73, 79 |
| abstract_inverted_index.heart | 13, 30 |
| abstract_inverted_index.least | 102 |
| abstract_inverted_index.major | 198 |
| abstract_inverted_index.month | 273 |
| abstract_inverted_index.novel | 24 |
| abstract_inverted_index.p=0.9 | 257 |
| abstract_inverted_index.right | 35, 332 |
| abstract_inverted_index.serum | 212 |
| abstract_inverted_index.shown | 5 |
| abstract_inverted_index.study | 142, 346 |
| abstract_inverted_index.table | 180 |
| abstract_inverted_index.these | 376 |
| abstract_inverted_index.using | 137 |
| abstract_inverted_index.were: | 91 |
| abstract_inverted_index.while | 301 |
| abstract_inverted_index.≥18 | 93 |
| abstract_inverted_index.(basal | 214, 229 |
| abstract_inverted_index.(table | 336 |
| abstract_inverted_index.1Table | 386 |
| abstract_inverted_index.During | 194 |
| abstract_inverted_index.Longer | 370 |
| abstract_inverted_index.assess | 47 |
| abstract_inverted_index.both), | 259 |
| abstract_inverted_index.ceased | 263 |
| abstract_inverted_index.change | 243, 280, 316 |
| abstract_inverted_index.class. | 284 |
| abstract_inverted_index.during | 192, 270 |
| abstract_inverted_index.events | 200 |
| abstract_inverted_index.global | 319 |
| abstract_inverted_index.impact | 206 |
| abstract_inverted_index.mEq/L, | 218, 225 |
| abstract_inverted_index.months | 104, 153, 222, 235, 294 |
| abstract_inverted_index.p=0.7) | 226 |
| abstract_inverted_index.reduce | 7 |
| abstract_inverted_index.repair | 85 |
| abstract_inverted_index.serial | 145 |
| abstract_inverted_index.showed | 347 |
| abstract_inverted_index.strain | 321 |
| abstract_inverted_index.values | 210 |
| abstract_inverted_index.years, | 94 |
| abstract_inverted_index.(TAPSE, | 309 |
| abstract_inverted_index.1-month | 165, 250 |
| abstract_inverted_index.3-month | 169 |
| abstract_inverted_index.Funding | 378 |
| abstract_inverted_index.Methods | 58 |
| abstract_inverted_index.Mustard | 84 |
| abstract_inverted_index.Purpose | 43 |
| abstract_inverted_index.Results | 157 |
| abstract_inverted_index.Senning | 82 |
| abstract_inverted_index.adverse | 199 |
| abstract_inverted_index.confirm | 375 |
| abstract_inverted_index.disease | 31 |
| abstract_inverted_index.effects | 21 |
| abstract_inverted_index.failure | 14 |
| abstract_inverted_index.funding | 382 |
| abstract_inverted_index.highest | 189 |
| abstract_inverted_index.medical | 96 |
| abstract_inverted_index.ml/min, | 237 |
| abstract_inverted_index.months; | 256 |
| abstract_inverted_index.ongoing | 344 |
| abstract_inverted_index.optimal | 95 |
| abstract_inverted_index.p=0.7). | 238 |
| abstract_inverted_index.reduced | 16 |
| abstract_inverted_index.results | 341 |
| abstract_inverted_index.therapy | 97 |
| abstract_inverted_index.walking | 288 |
| abstract_inverted_index.≤40%. | 110 |
| abstract_inverted_index.(114±12 | 245 |
| abstract_inverted_index.6-minute | 287 |
| abstract_inverted_index.ACEi/ARB | 99 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Although | 239 |
| abstract_inverted_index.Baseline | 174 |
| abstract_inverted_index.However, | 19, 285 |
| abstract_inverted_index.Patients | 111 |
| abstract_inverted_index.arteries | 74, 80 |
| abstract_inverted_index.assessed | 134 |
| abstract_inverted_index.criteria | 90 |
| abstract_inverted_index.distance | 289 |
| abstract_inverted_index.efficacy | 50 |
| abstract_inverted_index.evidence | 360 |
| abstract_inverted_index.exercise | 364 |
| abstract_inverted_index.function | 132, 308, 335 |
| abstract_inverted_index.p=0.01). | 299 |
| abstract_inverted_index.patients | 27, 54, 66, 163, 262, 354 |
| abstract_inverted_index.pressure | 117 |
| abstract_inverted_index.protocol | 143 |
| abstract_inverted_index.sources: | 383 |
| abstract_inverted_index.systemic | 34 |
| abstract_inverted_index.systolic | 17, 115, 131, 307, 334, 368 |
| abstract_inverted_index.(365±120 | 295 |
| abstract_inverted_index.107.8±21 | 236 |
| abstract_inverted_index.113.9±19 | 247 |
| abstract_inverted_index.117.3±12 | 252 |
| abstract_inverted_index.498.3±71 | 297 |
| abstract_inverted_index.Inclusion | 89 |
| abstract_inverted_index.September | 60 |
| abstract_inverted_index.Treatment | 203 |
| abstract_inverted_index.completed | 164, 168 |
| abstract_inverted_index.corrected | 69 |
| abstract_inverted_index.enrolled. | 88 |
| abstract_inverted_index.excluded. | 129 |
| abstract_inverted_index.follow-up | 371 |
| abstract_inverted_index.function. | 18, 369 |
| abstract_inverted_index.including | 98 |
| abstract_inverted_index.increased | 290 |
| abstract_inverted_index.morbidity | 10 |
| abstract_inverted_index.mortality | 8 |
| abstract_inverted_index.patients' | 175 |
| abstract_inverted_index.potassium | 213 |
| abstract_inverted_index.reported. | 202 |
| abstract_inverted_index.tolerance | 365 |
| abstract_inverted_index.tolerated | 190, 352 |
| abstract_inverted_index.treatment | 155, 172, 265 |
| abstract_inverted_index.ventricle | 36 |
| abstract_inverted_index.warranted | 373 |
| abstract_inverted_index.Background | 1 |
| abstract_inverted_index.assessment | 170 |
| abstract_inverted_index.congenital | 29 |
| abstract_inverted_index.filtration | 121 |
| abstract_inverted_index.follow-up, | 196 |
| abstract_inverted_index.follow-up. | 193 |
| abstract_inverted_index.glomerular | 120 |
| abstract_inverted_index.inpatients | 11 |
| abstract_inverted_index.medication | 183 |
| abstract_inverted_index.parameters | 304 |
| abstract_inverted_index.short-term | 340 |
| abstract_inverted_index.summarized | 178 |
| abstract_inverted_index.treatment. | 275 |
| abstract_inverted_index.Conclusions | 338 |
| abstract_inverted_index.[4.2–4.6] | 217 |
| abstract_inverted_index.[4.3–4.6] | 224 |
| abstract_inverted_index.assessments | 146 |
| abstract_inverted_index.association | 25 |
| abstract_inverted_index.evaluation. | 140 |
| abstract_inverted_index.hypotension | 269 |
| abstract_inverted_index.improvement | 330, 362 |
| abstract_inverted_index.initiation. | 156, 173 |
| abstract_inverted_index.physiology, | 114 |
| abstract_inverted_index.prospective | 345 |
| abstract_inverted_index.significant | 279 |
| abstract_inverted_index.subclinical | 329 |
| abstract_inverted_index.symptomatic | 268 |
| abstract_inverted_index.traditional | 302 |
| abstract_inverted_index.up-titrated | 186 |
| abstract_inverted_index.ventricular | 333 |
| abstract_inverted_index.Furthermore, | 300 |
| abstract_inverted_index.congenitally | 68 |
| abstract_inverted_index.contemplates | 144 |
| abstract_inverted_index.demonstrated | 328 |
| abstract_inverted_index.investigated | 41 |
| abstract_inverted_index.longitudinal | 320 |
| abstract_inverted_index.tolerability | 48 |
| abstract_inverted_index.prospectively | 87 |
| abstract_inverted_index.significantly | 207, 244, 291 |
| abstract_inverted_index.transposition | 70, 76 |
| abstract_inverted_index.significantly, | 317 |
| abstract_inverted_index.univentricular | 113 |
| abstract_inverted_index.&lt;90mmHg, | 119 |
| abstract_inverted_index.Acknowledgement | 379 |
| abstract_inverted_index.characteristics | 176 |
| abstract_inverted_index.multiparametric | 139 |
| abstract_inverted_index.&gt;5.5mEq/L | 127 |
| abstract_inverted_index.&lt;30ml/min | 124 |
| abstract_inverted_index.113.9±35ml/min, | 231 |
| abstract_inverted_index.echocardiography | 136 |
| abstract_inverted_index.echocardiographic | 303 |
| abstract_inverted_index.Sacubitril/valsartan | 2 |
| abstract_inverted_index.sacubitril/valsartan | 52, 349 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 14 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8700000047683716 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.19601671 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |