EFFECTS OF SAGYDI (SAD) ON ENDOGENOUS DYSLIPIDEMIA MODEL IN MICE Article Swipe
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· 2024
· Open Access
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· DOI: https://doi.org/10.51298/vmj.v538i1.9548
Dyslipidemia is one of the popular issues in developed countries and an increasing trend in developing countries. It is a major risk factor for cardiovascular disease, hypertension and diabetes. Polyherbal formulations have been used to treat dyslipidemia for many years. This study was designed to evaluate the effects of SAGYDI (SAD) on endogenous dyslipidemia experimental animal model. In endogenous hyperlipidemia model, mice were previously treated by SAD and intraperitoneally injected by poloxamer - 407 to induce hyperlipidemia. They were divided into groups and intraperitoneally injected with a 2% P-407 solution, followed by oral administration of varying doses of SAD. The results showed that SAD at the daily doses of 0.72g dried extract/kg and 2.16g dried extract/kg significantly reduced the serum total cholesterol (TC) levels and serum non-HDL cholesterol levels by 13.56%, 14.49%, and 16.40%, 11.10%, respectively (p<0.05). So, SAD has demonstrated an impact on serum lipid modulations in endogenous dyslipidemia model in mice.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.51298/vmj.v538i1.9548
- https://tapchiyhocvietnam.vn/index.php/vmj/article/download/9548/8414
- OA Status
- diamond
- References
- 7
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4396823150
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4396823150Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.51298/vmj.v538i1.9548Digital Object Identifier
- Title
-
EFFECTS OF SAGYDI (SAD) ON ENDOGENOUS DYSLIPIDEMIA MODEL IN MICEWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-05-11Full publication date if available
- Authors
-
Thi Van Anh Pham, Thuy Duong Dau, Nguyễn Thị Thanh ThủyList of authors in order
- Landing page
-
https://doi.org/10.51298/vmj.v538i1.9548Publisher landing page
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https://tapchiyhocvietnam.vn/index.php/vmj/article/download/9548/8414Direct link to full text PDF
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YesWhether a free full text is available
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-
diamondOpen access status per OpenAlex
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https://tapchiyhocvietnam.vn/index.php/vmj/article/download/9548/8414Direct OA link when available
- Concepts
-
Dyslipidemia, Hyperlipidemia, Endogeny, Medicine, Internal medicine, Diabetes mellitus, Endocrinology, Poloxamer 407, Cholesterol, Pharmacology, Chemistry, Poloxamer, Copolymer, Polymer, Organic chemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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7Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.evaluate | 45 |
| abstract_inverted_index.followed | 90 |
| abstract_inverted_index.injected | 69, 84 |
| abstract_inverted_index.countries | 9 |
| abstract_inverted_index.developed | 8 |
| abstract_inverted_index.diabetes. | 28 |
| abstract_inverted_index.poloxamer | 71 |
| abstract_inverted_index.solution, | 89 |
| abstract_inverted_index.Polyherbal | 29 |
| abstract_inverted_index.countries. | 16 |
| abstract_inverted_index.developing | 15 |
| abstract_inverted_index.endogenous | 52, 58, 148 |
| abstract_inverted_index.extract/kg | 111, 115 |
| abstract_inverted_index.increasing | 12 |
| abstract_inverted_index.previously | 63 |
| abstract_inverted_index.cholesterol | 121, 127 |
| abstract_inverted_index.modulations | 146 |
| abstract_inverted_index.(p<0.05). | 136 |
| abstract_inverted_index.Dyslipidemia | 0 |
| abstract_inverted_index.demonstrated | 140 |
| abstract_inverted_index.dyslipidemia | 36, 53, 149 |
| abstract_inverted_index.experimental | 54 |
| abstract_inverted_index.formulations | 30 |
| abstract_inverted_index.hypertension | 26 |
| abstract_inverted_index.respectively | 135 |
| abstract_inverted_index.significantly | 116 |
| abstract_inverted_index.administration | 93 |
| abstract_inverted_index.cardiovascular | 24 |
| abstract_inverted_index.hyperlipidemia | 59 |
| abstract_inverted_index.hyperlipidemia. | 76 |
| abstract_inverted_index.intraperitoneally | 68, 83 |
| cited_by_percentile_year | |
| corresponding_author_ids | https://openalex.org/A5083068575, https://openalex.org/A5058684461, https://openalex.org/A5103095988 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 3 |
| corresponding_institution_ids | https://openalex.org/I189643551 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/17 |
| sustainable_development_goals[0].score | 0.5299999713897705 |
| sustainable_development_goals[0].display_name | Partnerships for the goals |
| citation_normalized_percentile.value | 0.12257378 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |