Effects of Salidroside on Trabecular Meshwork Cell Extracellular Matrix Expression and Mouse Intraocular Pressure Article Swipe
Related Concepts
Salidroside
Trabecular meshwork
Immunocytochemistry
Extracellular matrix
Fibronectin
Chemistry
Western blot
Extracellular
Intraocular pressure
Blot
Rhodiola
Molecular biology
Pharmacology
Endocrinology
Medicine
Biology
Biochemistry
Ophthalmology
Gene
Yu‐Chen Fan
,
Li Guo
,
Jiahong Wei
,
Junzhao Chen
,
Hao Sun
,
Tao Guo
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1167/iovs.19-26585
· OA: W2945268093
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1167/iovs.19-26585
· OA: W2945268093
These results demonstrated that salidroside is capable of minimizing TGF-β2-induced ECM expression in cultured human TM cells. It also reduced TGF-β2-induced ocular hypertension in the mouse. These findings indicate that this phenolic glycoside may be useful as a novel treatment for POAG.
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