Effervescent tablets: a safe and practical delivery system for drug administration Article Swipe

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Kağan İpçi , Tuğba Öktemer , Leman Birdane , Niyazi Altıntoprak , Nuray Bayar Muluk , Desiderio Passàli , Andrey Lopatin , Luisa Bellussi , Ranko Mladina , Ruby Pawankar , Cemal Cingi ·

YOU? · · 2016 · Open Access · · DOI: https://doi.org/10.2399/jmu.2016001009

Effervescence is defined as the evolution of gas bubbles from a liquid as a result of a chemical reaction. For medicinal use, effervescent tablets have specific characteristics that allow rapid adsorption of the intended drug. In this manner, a medication can be absorbed easily and effectively if it dissolves easily in water and is present at a sufficient dose. Common acids utilized for effervescent reactions are citric, malic, tartaric, adipic and fumaric acids. Citric acid is most commonly used for this application, which also adds a citrus-like taste to the products. Tartaric, adipic and fumaric acids are usually used in small amounts, due to their low water solubility. Effervescent tablets are used to simplify the handling of doses, provide optimal compatibility, promote superior and rapid absorption, increase a patient's liquid intake and circumvent the difficulty of swallow- ing large pills. This review defines effervescent tablets in terms of the technology and describes the advantages and disadvantages.

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Drug delivery Drug Pharmacology Administration (probate law) Immediate release Medicine Drug administration Materials science Nanotechnology Political science Law

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Type: article
Language: en
Landing Page: https://doi.org/10.2399/jmu.2016001009
PDF: http://www.jmedupdates.org/Port_Doc/ENT_2016/ENT_2016001/ENT_2016001009.pdf
OA Status: diamond
Cited By: 41
References: 16
Related Works: 10
OpenAlex ID: https://openalex.org/W2344038980

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DOI: https://doi.org/10.2399/jmu.2016001009

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Title: Effervescent tablets: a safe and practical delivery system for drug administration

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Type: article

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Language: en

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Publication year: 2016

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Publication date: 2016-04-01

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Authors: Kağan İpçi, Tuğba Öktemer, Leman Birdane, Niyazi Altıntoprak, Nuray Bayar Muluk, Desiderio Passàli, Andrey Lopatin, Luisa Bellussi, Ranko Mladina, Ruby Pawankar, Cemal Cingi

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Landing page: https://doi.org/10.2399/jmu.2016001009

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PDF URL: https://www.jmedupdates.org/Port_Doc/ENT_2016/ENT_2016001/ENT_2016001009.pdf

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Concepts: Drug delivery, Drug, Pharmacology, Administration (probate law), Immediate release, Medicine, Drug administration, Materials science, Nanotechnology, Political science, Law

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Cited by: 41

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Citations by year (recent): 2025: 7, 2024: 7, 2023: 7, 2022: 6, 2021: 8

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