Efficacy and safety of dexamethasone versus intravitreal aflibercept implants for macular edema: a systematic review and meta-analysis Article Swipe
Khaled Moghib
,
Trisha Shivashankar
,
Abdallah Abunamoos
,
Al Hasan Mia
,
Izere Salomon
,
Thoria Ibrahim Essa ghanm
,
Ali Salah
,
Mohamed A. Aldemerdash
,
Mona I Elshamy
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s40001-025-02404-x
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s40001-025-02404-x
Intravitreal aflibercept injections and dexamethasone implants are effective modalities for the management of ME, with each presenting distinct advantages. Dexamethasone implants minimize the frequency of treatment, while achieving superior outcomes in terms of BCVA and CRT. However, they are also associated with a heightened risk of IOP elevation and cataract formation. Conversely, aflibercept requires more frequent administration, which may result in logistical and financial challenges for patients and health care providers. Therefore, personalized treatment strategies should consider disease severity, comorbidities, and individual preferences. Future research should prioritize patient-centered outcomes, emphasizing quality of life and treatment costs while also investigating condition-specific responses to these therapeutic interventions.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1186/s40001-025-02404-x
- https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-025-02404-x
- OA Status
- gold
- Cited By
- 1
- References
- 47
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4409479262
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4409479262Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s40001-025-02404-xDigital Object Identifier
- Title
-
Efficacy and safety of dexamethasone versus intravitreal aflibercept implants for macular edema: a systematic review and meta-analysisWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-04-15Full publication date if available
- Authors
-
Khaled Moghib, Trisha Shivashankar, Abdallah Abunamoos, Al Hasan Mia, Izere Salomon, Thoria Ibrahim Essa ghanm, Ali Salah, Mohamed A. Aldemerdash, Mona I ElshamyList of authors in order
- Landing page
-
https://doi.org/10.1186/s40001-025-02404-xPublisher landing page
- PDF URL
-
https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-025-02404-xDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-025-02404-xDirect OA link when available
- Concepts
-
Aflibercept, Medicine, Macular edema, Meta-analysis, Dexamethasone, Ophthalmology, MEDLINE, Bevacizumab, Surgery, Internal medicine, Visual acuity, Chemotherapy, Chemistry, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
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-
2025: 1Per-year citation counts (last 5 years)
- References (count)
-
47Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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