ELIXIR and Toxicology: a community in development Article Swipe

MAKE IMPACT

Marvin Martens , Rob Stierum , Emma Schymanski , Chris T. Evelo , Reza Aalizadeh , Hristo Aladjov , Katarzyna Arturi , Karine Audouze , Pavel Babica , Karel Berka , Jos Bessems , Luděk Bláha , Evan Bolton , Montserrat Cases , Dimitrios Ε. Damalas , Kirtan Dave , Marco Dilger , Thomas E. Exner , Daan P. Geerke , Roland Grafström , Alasdair J. G. Gray , John M. Hancock , Henner Hollert , Nina Jeliazkova , Danyel Jennen , Fabien Jourdan , Pascal Kahlem , Jana Klánová , Jos Kleinjans , Todor Kondić , Boï Kone , Iseult Lynch , Uko Maran , Sergio Martínez Cuesta , Hervé Ménager , Steffen Neumann , Penny Nymark , Herbert Oberacher , Noelia Ramírez , Sylvie Rémy , Philippe Rocca‐Serra , Reza M. Salek , Brett Sallach , Susanna‐Assunta Sansone , Ferrán Sanz , Haralambos Sarimveis , Sirarat Sarntivijai , Tobias Schulze , Jaroslav Slobodnı́k , Ola Spjuth , Jonathan Tedds , Νikolaos S. Τhomaidis , Ralf J. M. Weber , Gerard J. P. van Westen , Craig E. Wheelock , Antony Williams , Hilda Witters , Barbara Zdrazil , Anže Županič , Egon Willighagen · YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.12688/f1000research.74502.2

Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology, and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.

Type

preprint

Language

en

Landing Page

https://doi.org/10.12688/f1000research.74502.2

OA Status

gold

Cited By

5

References

64

Related Works

10

OpenAlex ID

https://openalex.org/W4387300806

Raw OpenAlex JSON

OpenAlex ID

https://openalex.org/W4387300806

Canonical identifier for this work in OpenAlex

DOI

https://doi.org/10.12688/f1000research.74502.2

Digital Object Identifier

Title

ELIXIR and Toxicology: a community in development

Work title

Type

preprint

OpenAlex work type

Language

en

Primary language

Publication year

2023

Year of publication

Publication date

2023-10-03

Full publication date if available

Authors

Marvin Martens, Rob Stierum, Emma Schymanski, Chris T. Evelo, Reza Aalizadeh, Hristo Aladjov, Katarzyna Arturi, Karine Audouze, Pavel Babica, Karel Berka, Jos Bessems, Luděk Bláha, Evan Bolton, Montserrat Cases, Dimitrios Ε. Damalas, Kirtan Dave, Marco Dilger, Thomas E. Exner, Daan P. Geerke, Roland Grafström, Alasdair J. G. Gray, John M. Hancock, Henner Hollert, Nina Jeliazkova, Danyel Jennen, Fabien Jourdan, Pascal Kahlem, Jana Klánová, Jos Kleinjans, Todor Kondić, Boï Kone, Iseult Lynch, Uko Maran, Sergio Martínez Cuesta, Hervé Ménager, Steffen Neumann, Penny Nymark, Herbert Oberacher, Noelia Ramírez, Sylvie Rémy, Philippe Rocca‐Serra, Reza M. Salek, Brett Sallach, Susanna‐Assunta Sansone, Ferrán Sanz, Haralambos Sarimveis, Sirarat Sarntivijai, Tobias Schulze, Jaroslav Slobodnı́k, Ola Spjuth, Jonathan Tedds, Νikolaos S. Τhomaidis, Ralf J. M. Weber, Gerard J. P. van Westen, Craig E. Wheelock, Antony Williams, Hilda Witters, Barbara Zdrazil, Anže Županič, Egon Willighagen

List of authors in order

Landing page

https://doi.org/10.12688/f1000research.74502.2

Publisher landing page

Open access

Yes

Whether a free full text is available

OA status

gold

Open access status per OpenAlex

OA URL

https://doi.org/10.12688/f1000research.74502.2

Direct OA link when available

Concepts

Elixir (programming language), Repurposing, Context (archaeology), Medicine, Toxicology, Engineering ethics, Computer science, Engineering, Biology, Waste management, Paleontology, Programming language

Top concepts (fields/topics) attached by OpenAlex

Cited by

5

Total citation count in OpenAlex

Citations by year (recent)

2025: 3, 2024: 2

Per-year citation counts (last 5 years)

References (count)

64

Number of works referenced by this work

Related works (count)

10

Other works algorithmically related by OpenAlex

Full payload