Emergency Wound Infection Monitoring and Treatment Based on Wearable Electrochemical Detection and Drug Release with Conductive Hydrogel Article Swipe
Shaopeng Wang
,
Songsong Huang
,
Qian Chen
,
Yanjun Li
,
Lei Duan
,
Zhi Yu
,
Weixia Li
,
Hui Luo
,
Shuang Li
,
Bin Fan
,
Zetao Chen
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/chemosensors13070267
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/chemosensors13070267
At emergency sites, bacteria in the environment can cause secondary wound infections. Timely treatment of infected wounds can improve the prognosis. In this study, we designed a closed-loop system for real-time wound infection monitoring and electronically controlled drug release, enabling rapid and stable deployment at disaster sites. Multilayer screen-printed electrodes were developed to detect uric acid (UA), pH, and temperature biomarkers. The electrode’s outermost layer was shielded by a zwitterionic conductive hydrogel (Gel) to prevent environmental interference and achieve systematic antibacterial protection through in situ reduction of silver nanoparticles (AgNPs) on its surface. For rapid and efficient drug delivery, amikacin (Ami) loaded cationic liposomes (Lipo) embedded in the zwitterionic conductive hydrogel (Gel-Lipo@Ami) were integrated as the core therapeutic carrier. This closed-loop system provides timely infection detection and enables in situ treatment during emergency rescues.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/chemosensors13070267
- https://www.mdpi.com/2227-9040/13/7/267/pdf?version=1753106041
- OA Status
- gold
- References
- 71
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4412526369
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4412526369Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/chemosensors13070267Digital Object Identifier
- Title
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Emergency Wound Infection Monitoring and Treatment Based on Wearable Electrochemical Detection and Drug Release with Conductive HydrogelWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-07-21Full publication date if available
- Authors
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Shaopeng Wang, Songsong Huang, Qian Chen, Yanjun Li, Lei Duan, Zhi Yu, Weixia Li, Hui Luo, Shuang Li, Bin Fan, Zetao ChenList of authors in order
- Landing page
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https://doi.org/10.3390/chemosensors13070267Publisher landing page
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https://www.mdpi.com/2227-9040/13/7/267/pdf?version=1753106041Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2227-9040/13/7/267/pdf?version=1753106041Direct OA link when available
- Concepts
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Wearable computer, Drug, Electrical conductor, Electrochemistry, Biomedical engineering, Materials science, Nanotechnology, Medicine, Chemistry, Pharmacology, Computer science, Electrode, Embedded system, Composite material, Physical chemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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71Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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