Epidemiological, clinical, and biological profiles of People Living With HIV in the PMTCT department of Panzi hospital: a retrospective cohort study in Eastern DR. Congo Article Swipe
Berckmans Mukanire Ntakwinja
,
Patrick DMC Katoto
,
Omari Mukanga
,
Jacques Lukenze Tamuzi
,
Mireille AM Kakubu
,
Benjamin Tshizubu
,
Maguette Gaye Sakho
,
Bihehe Masemo
,
Aline Byabene
,
Éric Florence
,
Philémon Mulongo
,
Tshasinga Tshass
,
Denis Mukwege
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s12981-025-00796-8
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s12981-025-00796-8
Among the 9,143 women enrolled in PMTCT, 6,318 were tested, of whom 256 (4.1%) were HIV-positive, including 112 pregnant women (1.8%). Compared with their HIV-negative counterparts, HIV-positive pregnant women had lower antenatal care attendance compared with HIV-negative counterparts. The main opportunistic infections were candidiasis and genital herpes (2.7% each). Only 58% had available CD4 counts, all above 500 cells/ml. An undetectable viral load (< 30copies/l) was recorded in 60.7% of cases. Liver and renal dysfunctions were observed in 6.2% and 30.3% of patients, respectively, wereas d anemia (< 12 g/dl) affected 61.6%. In multivariable analysis, HIV infection was associated with age < 20 years (aOR = 7.20), primary education (aOR = 5.30), household income of $50-100/month (aOR = 56.4), primiparity (aOR = 10.68), and poverty (aOR = 18). Conversely, multigravidity (aOR = 0.19) and residence in the Ibanda and Kadutu health zones were protective factors CONCLUSION: Epidemiological and biological profiles strongly influence PMTCT outcomes. Strengthening HIV testing, expanding ART access, and routine viral load monitoring particularly among young and primiparous women are essential to improve maternal and neonatal health outcomes in the DRC.
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- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s12981-025-00796-8
- https://aidsrestherapy.biomedcentral.com/counter/pdf/10.1186/s12981-025-00796-8
- OA Status
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- References
- 39
- OpenAlex ID
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4415421259Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1186/s12981-025-00796-8Digital Object Identifier
- Title
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Epidemiological, clinical, and biological profiles of People Living With HIV in the PMTCT department of Panzi hospital: a retrospective cohort study in Eastern DR. CongoWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-10-22Full publication date if available
- Authors
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Berckmans Mukanire Ntakwinja, Patrick DMC Katoto, Omari Mukanga, Jacques Lukenze Tamuzi, Mireille AM Kakubu, Benjamin Tshizubu, Maguette Gaye Sakho, Bihehe Masemo, Aline Byabene, Éric Florence, Philémon Mulongo, Tshasinga Tshass, Denis MukwegeList of authors in order
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https://doi.org/10.1186/s12981-025-00796-8Publisher landing page
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https://aidsrestherapy.biomedcentral.com/counter/pdf/10.1186/s12981-025-00796-8Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://aidsrestherapy.biomedcentral.com/counter/pdf/10.1186/s12981-025-00796-8Direct OA link when available
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| abstract_inverted_index.61.6%. | 91 |
| abstract_inverted_index.7.20), | 106 |
| abstract_inverted_index.Ibanda | 137 |
| abstract_inverted_index.Kadutu | 139 |
| abstract_inverted_index.PMTCT, | 6 |
| abstract_inverted_index.anemia | 86 |
| abstract_inverted_index.cases. | 70 |
| abstract_inverted_index.each). | 48 |
| abstract_inverted_index.health | 140, 178 |
| abstract_inverted_index.herpes | 46 |
| abstract_inverted_index.income | 113 |
| abstract_inverted_index.wereas | 84 |
| abstract_inverted_index.(1.8%). | 20 |
| abstract_inverted_index.10.68), | 122 |
| abstract_inverted_index.access, | 159 |
| abstract_inverted_index.counts, | 54 |
| abstract_inverted_index.factors | 144 |
| abstract_inverted_index.genital | 45 |
| abstract_inverted_index.improve | 174 |
| abstract_inverted_index.poverty | 124 |
| abstract_inverted_index.primary | 107 |
| abstract_inverted_index.routine | 161 |
| abstract_inverted_index.tested, | 9 |
| abstract_inverted_index.Compared | 21 |
| abstract_inverted_index.affected | 90 |
| abstract_inverted_index.compared | 34 |
| abstract_inverted_index.enrolled | 4 |
| abstract_inverted_index.maternal | 175 |
| abstract_inverted_index.neonatal | 177 |
| abstract_inverted_index.observed | 76 |
| abstract_inverted_index.outcomes | 179 |
| abstract_inverted_index.pregnant | 18, 27 |
| abstract_inverted_index.profiles | 149 |
| abstract_inverted_index.recorded | 66 |
| abstract_inverted_index.strongly | 150 |
| abstract_inverted_index.testing, | 156 |
| abstract_inverted_index.analysis, | 94 |
| abstract_inverted_index.antenatal | 31 |
| abstract_inverted_index.available | 52 |
| abstract_inverted_index.cells/ml. | 58 |
| abstract_inverted_index.education | 108 |
| abstract_inverted_index.essential | 172 |
| abstract_inverted_index.expanding | 157 |
| abstract_inverted_index.household | 112 |
| abstract_inverted_index.including | 16 |
| abstract_inverted_index.infection | 96 |
| abstract_inverted_index.influence | 151 |
| abstract_inverted_index.outcomes. | 153 |
| abstract_inverted_index.patients, | 82 |
| abstract_inverted_index.residence | 134 |
| abstract_inverted_index.associated | 98 |
| abstract_inverted_index.attendance | 33 |
| abstract_inverted_index.biological | 148 |
| abstract_inverted_index.infections | 41 |
| abstract_inverted_index.monitoring | 164 |
| abstract_inverted_index.protective | 143 |
| abstract_inverted_index.30copies/l) | 64 |
| abstract_inverted_index.CONCLUSION: | 145 |
| abstract_inverted_index.Conversely, | 128 |
| abstract_inverted_index.candidiasis | 43 |
| abstract_inverted_index.primiparity | 119 |
| abstract_inverted_index.primiparous | 169 |
| abstract_inverted_index.HIV-negative | 24, 36 |
| abstract_inverted_index.HIV-positive | 26 |
| abstract_inverted_index.dysfunctions | 74 |
| abstract_inverted_index.particularly | 165 |
| abstract_inverted_index.undetectable | 60 |
| abstract_inverted_index.$50-100/month | 115 |
| abstract_inverted_index.HIV-positive, | 15 |
| abstract_inverted_index.Strengthening | 154 |
| abstract_inverted_index.counterparts, | 25 |
| abstract_inverted_index.counterparts. | 37 |
| abstract_inverted_index.multivariable | 93 |
| abstract_inverted_index.opportunistic | 40 |
| abstract_inverted_index.respectively, | 83 |
| abstract_inverted_index.multigravidity | 129 |
| abstract_inverted_index.Epidemiological | 146 |
| cited_by_percentile_year | |
| corresponding_author_ids | https://openalex.org/A5084328298 |
| countries_distinct_count | 3 |
| institutions_distinct_count | 13 |
| corresponding_institution_ids | https://openalex.org/I2802546094, https://openalex.org/I4210121414, https://openalex.org/I4210125054 |
| citation_normalized_percentile.value | 0.59401362 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |