Establishment of patient-derived tumor organoids to functionally inform treatment decisions in metastatic colorectal cancer Article Swipe

View

Giulia Martini , Valentina Belli , Stefania Napolitano , Vincenza Ciaramella , Davide Ciardiello , A Belli , Franco Izzo , Antonio Avallone , Francesco Selvaggi , F Menegon Tasselli , W Santaniello , Renato Franco , Isabel Puig , Lorena Ramírez , Irene Chicote , Francesco M. Mancuso , Ginevra Caratù , X Serres , Roberta Fasani , José Jimenez , Javier Ros , Iosune Baraibar , Nuria Mulet , Carminia Maria Della Corte , Teresa Troiani , Ana Vivancos , Rodrigo Dienstmann , Elena Élez , Héctor G. Pálmer , Josep Tabernero , Erika Martinelli , Fortunato Ciardiello , Guillem Argilés ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1016/j.esmoop.2023.101198

Using CRC as a model, we have designed and validated a clinically applicable methodology to potentially inform clinical decisions with functional data. Undoubtedly, further larger analyses are needed to improve methodology success rates and propose suitable treatment strategies for mCRC patients.

Related Topics

Concepts

Bevacizumab Cetuximab Colorectal cancer Medicine KRAS Oncology Cohort Internal medicine Nivolumab FOLFOX Genotyping Oxaliplatin Chemotherapy Cancer Biology Immunotherapy Genotype Biochemistry Gene

Metadata

Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.esmoop.2023.101198
OA Status: gold
Cited By: 28
References: 20
Related Works: 10
OpenAlex ID: https://openalex.org/W4367291411

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W4367291411

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1016/j.esmoop.2023.101198

Digital Object Identifier
Title: Establishment of patient-derived tumor organoids to functionally inform treatment decisions in metastatic colorectal cancer

Work title
Type: article

OpenAlex work type
Language: en

Primary language
Publication year: 2023

Year of publication
Publication date: 2023-04-27

Full publication date if available
Authors: Giulia Martini, Valentina Belli, Stefania Napolitano, Vincenza Ciaramella, Davide Ciardiello, A Belli, Franco Izzo, Antonio Avallone, Francesco Selvaggi, F Menegon Tasselli, W Santaniello, Renato Franco, Isabel Puig, Lorena Ramírez, Irene Chicote, Francesco M. Mancuso, Ginevra Caratù, X Serres, Roberta Fasani, José Jimenez, Javier Ros, Iosune Baraibar, Nuria Mulet, Carminia Maria Della Corte, Teresa Troiani, Ana Vivancos, Rodrigo Dienstmann, Elena Élez, Héctor G. Pálmer, Josep Tabernero, Erika Martinelli, Fortunato Ciardiello, Guillem Argilés

List of authors in order
Landing page: https://doi.org/10.1016/j.esmoop.2023.101198

Publisher landing page
Open access: Yes

Whether a free full text is available
OA status: gold

Open access status per OpenAlex
OA URL: https://doi.org/10.1016/j.esmoop.2023.101198

Direct OA link when available
Concepts: Bevacizumab, Cetuximab, Colorectal cancer, Medicine, KRAS, Oncology, Cohort, Internal medicine, Nivolumab, FOLFOX, Genotyping, Oxaliplatin, Chemotherapy, Cancer, Biology, Immunotherapy, Genotype, Biochemistry, Gene

Top concepts (fields/topics) attached by OpenAlex
Cited by: 28

Total citation count in OpenAlex
Citations by year (recent): 2025: 12, 2024: 10, 2023: 6

Per-year citation counts (last 5 years)
References (count): 20

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W4367291411
doi	https://doi.org/10.1016/j.esmoop.2023.101198
ids.doi	https://doi.org/10.1016/j.esmoop.2023.101198
ids.pmid	https://pubmed.ncbi.nlm.nih.gov/37119788
ids.openalex	https://openalex.org/W4367291411
fwci	7.1279108
mesh[0].qualifier_ui
mesh[0].descriptor_ui	D006801
mesh[0].is_major_topic	False
mesh[0].qualifier_name
mesh[0].descriptor_name	Humans
mesh[1].qualifier_ui	Q000009
mesh[1].descriptor_ui	D000068818
mesh[1].is_major_topic	False
mesh[1].qualifier_name	adverse effects
mesh[1].descriptor_name	Cetuximab
mesh[2].qualifier_ui	Q000188
mesh[2].descriptor_ui	D015179
mesh[2].is_major_topic	True
mesh[2].qualifier_name	drug therapy
mesh[2].descriptor_name	Colorectal Neoplasms
mesh[3].qualifier_ui	Q000235
mesh[3].descriptor_ui	D015179
mesh[3].is_major_topic	True
mesh[3].qualifier_name	genetics
mesh[3].descriptor_name	Colorectal Neoplasms
mesh[4].qualifier_ui	Q000473
mesh[4].descriptor_ui	D015179
mesh[4].is_major_topic	True
mesh[4].qualifier_name	pathology
mesh[4].descriptor_name	Colorectal Neoplasms
mesh[5].qualifier_ui
mesh[5].descriptor_ui	D003110
mesh[5].is_major_topic	True
mesh[5].qualifier_name
mesh[5].descriptor_name	Colonic Neoplasms
mesh[6].qualifier_ui
mesh[6].descriptor_ui	D009154
mesh[6].is_major_topic	False
mesh[6].qualifier_name
mesh[6].descriptor_name	Mutation
mesh[7].qualifier_ui
mesh[7].descriptor_ui	D006801
mesh[7].is_major_topic	False
mesh[7].qualifier_name
mesh[7].descriptor_name	Humans
mesh[8].qualifier_ui	Q000009
mesh[8].descriptor_ui	D000068818
mesh[8].is_major_topic	False
mesh[8].qualifier_name	adverse effects
mesh[8].descriptor_name	Cetuximab
mesh[9].qualifier_ui	Q000188
mesh[9].descriptor_ui	D015179
mesh[9].is_major_topic	True
mesh[9].qualifier_name	drug therapy
mesh[9].descriptor_name	Colorectal Neoplasms
mesh[10].qualifier_ui	Q000235
mesh[10].descriptor_ui	D015179
mesh[10].is_major_topic	True
mesh[10].qualifier_name	genetics
mesh[10].descriptor_name	Colorectal Neoplasms
mesh[11].qualifier_ui	Q000473
mesh[11].descriptor_ui	D015179
mesh[11].is_major_topic	True
mesh[11].qualifier_name	pathology
mesh[11].descriptor_name	Colorectal Neoplasms
mesh[12].qualifier_ui
mesh[12].descriptor_ui	D003110
mesh[12].is_major_topic	True
mesh[12].qualifier_name
mesh[12].descriptor_name	Colonic Neoplasms
mesh[13].qualifier_ui
mesh[13].descriptor_ui	D009154
mesh[13].is_major_topic	False
mesh[13].qualifier_name
mesh[13].descriptor_name	Mutation
mesh[14].qualifier_ui
mesh[14].descriptor_ui	D006801
mesh[14].is_major_topic	False
mesh[14].qualifier_name
mesh[14].descriptor_name	Humans
mesh[15].qualifier_ui	Q000009
mesh[15].descriptor_ui	D000068818
mesh[15].is_major_topic	False
mesh[15].qualifier_name	adverse effects
mesh[15].descriptor_name	Cetuximab
mesh[16].qualifier_ui	Q000188
mesh[16].descriptor_ui	D015179
mesh[16].is_major_topic	True
mesh[16].qualifier_name	drug therapy
mesh[16].descriptor_name	Colorectal Neoplasms
mesh[17].qualifier_ui	Q000235
mesh[17].descriptor_ui	D015179
mesh[17].is_major_topic	True
mesh[17].qualifier_name	genetics
mesh[17].descriptor_name	Colorectal Neoplasms
mesh[18].qualifier_ui	Q000473
mesh[18].descriptor_ui	D015179
mesh[18].is_major_topic	True
mesh[18].qualifier_name	pathology
mesh[18].descriptor_name	Colorectal Neoplasms
mesh[19].qualifier_ui
mesh[19].descriptor_ui	D003110
mesh[19].is_major_topic	True
mesh[19].qualifier_name
mesh[19].descriptor_name	Colonic Neoplasms
mesh[20].qualifier_ui
mesh[20].descriptor_ui	D009154
mesh[20].is_major_topic	False
mesh[20].qualifier_name
mesh[20].descriptor_name	Mutation
type	article
title	Establishment of patient-derived tumor organoids to functionally inform treatment decisions in metastatic colorectal cancer
biblio.issue	3
biblio.volume	8
biblio.last_page	101198
biblio.first_page	101198
topics[0].id	https://openalex.org/T10336
topics[0].field.id	https://openalex.org/fields/27
topics[0].field.display_name	Medicine
topics[0].score	0.9994999766349792
topics[0].domain.id	https://openalex.org/domains/4
topics[0].domain.display_name	Health Sciences
topics[0].subfield.id	https://openalex.org/subfields/2730
topics[0].subfield.display_name	Oncology
topics[0].display_name	Cancer Cells and Metastasis
topics[1].id	https://openalex.org/T11287
topics[1].field.id	https://openalex.org/fields/13
topics[1].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[1].score	0.9973000288009644
topics[1].domain.id	https://openalex.org/domains/1
topics[1].domain.display_name	Life Sciences
topics[1].subfield.id	https://openalex.org/subfields/1306
topics[1].subfield.display_name	Cancer Research
topics[1].display_name	Cancer Genomics and Diagnostics
topics[2].id	https://openalex.org/T12996
topics[2].field.id	https://openalex.org/fields/13
topics[2].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[2].score	0.992900013923645
topics[2].domain.id	https://openalex.org/domains/1
topics[2].domain.display_name	Life Sciences
topics[2].subfield.id	https://openalex.org/subfields/1305
topics[2].subfield.display_name	Biotechnology
topics[2].display_name	Cancer Research and Treatments
is_xpac	False
apc_list.value	2750
apc_list.currency	EUR
apc_list.value_usd	2965
apc_paid.value	2750
apc_paid.currency	EUR
apc_paid.value_usd	2965
concepts[0].id	https://openalex.org/C2777802072
concepts[0].level	3
concepts[0].score	0.8004186153411865
concepts[0].wikidata	https://www.wikidata.org/wiki/Q413299
concepts[0].display_name	Bevacizumab
concepts[1].id	https://openalex.org/C2779998722
concepts[1].level	4
concepts[1].score	0.7941533327102661
concepts[1].wikidata	https://www.wikidata.org/wiki/Q420296
concepts[1].display_name	Cetuximab
concepts[2].id	https://openalex.org/C526805850
concepts[2].level	3
concepts[2].score	0.7292844653129578
concepts[2].wikidata	https://www.wikidata.org/wiki/Q188874
concepts[2].display_name	Colorectal cancer
concepts[3].id	https://openalex.org/C71924100
concepts[3].level	0
concepts[3].score	0.7287368178367615
concepts[3].wikidata	https://www.wikidata.org/wiki/Q11190
concepts[3].display_name	Medicine
concepts[4].id	https://openalex.org/C2781187634
concepts[4].level	4
concepts[4].score	0.6505476832389832
concepts[4].wikidata	https://www.wikidata.org/wiki/Q20969980
concepts[4].display_name	KRAS
concepts[5].id	https://openalex.org/C143998085
concepts[5].level	1
concepts[5].score	0.6322553157806396
concepts[5].wikidata	https://www.wikidata.org/wiki/Q162555
concepts[5].display_name	Oncology
concepts[6].id	https://openalex.org/C72563966
concepts[6].level	2
concepts[6].score	0.6217824816703796
concepts[6].wikidata	https://www.wikidata.org/wiki/Q1303415
concepts[6].display_name	Cohort
concepts[7].id	https://openalex.org/C126322002
concepts[7].level	1
concepts[7].score	0.606297492980957
concepts[7].wikidata	https://www.wikidata.org/wiki/Q11180
concepts[7].display_name	Internal medicine
concepts[8].id	https://openalex.org/C2780030458
concepts[8].level	4
concepts[8].score	0.4899224638938904
concepts[8].wikidata	https://www.wikidata.org/wiki/Q7041828
concepts[8].display_name	Nivolumab
concepts[9].id	https://openalex.org/C2778260052
concepts[9].level	5
concepts[9].score	0.4695739448070526
concepts[9].wikidata	https://www.wikidata.org/wiki/Q117636
concepts[9].display_name	FOLFOX
concepts[10].id	https://openalex.org/C31467283
concepts[10].level	4
concepts[10].score	0.46603816747665405
concepts[10].wikidata	https://www.wikidata.org/wiki/Q912147
concepts[10].display_name	Genotyping
concepts[11].id	https://openalex.org/C2780962732
concepts[11].level	4
concepts[11].score	0.46166661381721497
concepts[11].wikidata	https://www.wikidata.org/wiki/Q422327
concepts[11].display_name	Oxaliplatin
concepts[12].id	https://openalex.org/C2776694085
concepts[12].level	2
concepts[12].score	0.4041190445423126
concepts[12].wikidata	https://www.wikidata.org/wiki/Q974135
concepts[12].display_name	Chemotherapy
concepts[13].id	https://openalex.org/C121608353
concepts[13].level	2
concepts[13].score	0.37242698669433594
concepts[13].wikidata	https://www.wikidata.org/wiki/Q12078
concepts[13].display_name	Cancer
concepts[14].id	https://openalex.org/C86803240
concepts[14].level	0
concepts[14].score	0.12412908673286438
concepts[14].wikidata	https://www.wikidata.org/wiki/Q420
concepts[14].display_name	Biology
concepts[15].id	https://openalex.org/C2777701055
concepts[15].level	3
concepts[15].score	0.09928148984909058
concepts[15].wikidata	https://www.wikidata.org/wiki/Q1427096
concepts[15].display_name	Immunotherapy
concepts[16].id	https://openalex.org/C135763542
concepts[16].level	3
concepts[16].score	0.07609370350837708
concepts[16].wikidata	https://www.wikidata.org/wiki/Q106016
concepts[16].display_name	Genotype
concepts[17].id	https://openalex.org/C55493867
concepts[17].level	1
concepts[17].score	0.0
concepts[17].wikidata	https://www.wikidata.org/wiki/Q7094
concepts[17].display_name	Biochemistry
concepts[18].id	https://openalex.org/C104317684
concepts[18].level	2
concepts[18].score	0.0
concepts[18].wikidata	https://www.wikidata.org/wiki/Q7187
concepts[18].display_name	Gene
keywords[0].id	https://openalex.org/keywords/bevacizumab
keywords[0].score	0.8004186153411865
keywords[0].display_name	Bevacizumab
keywords[1].id	https://openalex.org/keywords/cetuximab
keywords[1].score	0.7941533327102661
keywords[1].display_name	Cetuximab
keywords[2].id	https://openalex.org/keywords/colorectal-cancer
keywords[2].score	0.7292844653129578
keywords[2].display_name	Colorectal cancer
keywords[3].id	https://openalex.org/keywords/medicine
keywords[3].score	0.7287368178367615
keywords[3].display_name	Medicine
keywords[4].id	https://openalex.org/keywords/kras
keywords[4].score	0.6505476832389832
keywords[4].display_name	KRAS
keywords[5].id	https://openalex.org/keywords/oncology
keywords[5].score	0.6322553157806396
keywords[5].display_name	Oncology
keywords[6].id	https://openalex.org/keywords/cohort
keywords[6].score	0.6217824816703796
keywords[6].display_name	Cohort
keywords[7].id	https://openalex.org/keywords/internal-medicine
keywords[7].score	0.606297492980957
keywords[7].display_name	Internal medicine
keywords[8].id	https://openalex.org/keywords/nivolumab
keywords[8].score	0.4899224638938904
keywords[8].display_name	Nivolumab
keywords[9].id	https://openalex.org/keywords/folfox
keywords[9].score	0.4695739448070526
keywords[9].display_name	FOLFOX
keywords[10].id	https://openalex.org/keywords/genotyping
keywords[10].score	0.46603816747665405
keywords[10].display_name	Genotyping
keywords[11].id	https://openalex.org/keywords/oxaliplatin
keywords[11].score	0.46166661381721497
keywords[11].display_name	Oxaliplatin
keywords[12].id	https://openalex.org/keywords/chemotherapy
keywords[12].score	0.4041190445423126
keywords[12].display_name	Chemotherapy
keywords[13].id	https://openalex.org/keywords/cancer
keywords[13].score	0.37242698669433594
keywords[13].display_name	Cancer
keywords[14].id	https://openalex.org/keywords/biology
keywords[14].score	0.12412908673286438
keywords[14].display_name	Biology
keywords[15].id	https://openalex.org/keywords/immunotherapy
keywords[15].score	0.09928148984909058
keywords[15].display_name	Immunotherapy
keywords[16].id	https://openalex.org/keywords/genotype
keywords[16].score	0.07609370350837708
keywords[16].display_name	Genotype
language	en
locations[0].id	doi:10.1016/j.esmoop.2023.101198
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S4210217024
locations[0].source.issn	2059-7029
locations[0].source.type	journal
locations[0].source.is_oa	True
locations[0].source.issn_l	2059-7029
locations[0].source.is_core	True
locations[0].source.is_in_doaj	True
locations[0].source.display_name	ESMO Open
locations[0].source.host_organization	https://openalex.org/P4310320990
locations[0].source.host_organization_name	Elsevier BV
locations[0].source.host_organization_lineage	https://openalex.org/P4310320990
locations[0].source.host_organization_lineage_names	Elsevier BV
locations[0].license
locations[0].pdf_url
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	ESMO Open
locations[0].landing_page_url	https://doi.org/10.1016/j.esmoop.2023.101198
locations[1].id	pmid:37119788
locations[1].is_oa	False
locations[1].source.id	https://openalex.org/S4306525036
locations[1].source.issn
locations[1].source.type	repository
locations[1].source.is_oa	False
locations[1].source.issn_l
locations[1].source.is_core	False
locations[1].source.is_in_doaj	False
locations[1].source.display_name	PubMed
locations[1].source.host_organization	https://openalex.org/I1299303238
locations[1].source.host_organization_name	National Institutes of Health
locations[1].source.host_organization_lineage	https://openalex.org/I1299303238
locations[1].license
locations[1].pdf_url
locations[1].version	publishedVersion
locations[1].raw_type
locations[1].license_id
locations[1].is_accepted	True
locations[1].is_published	True
locations[1].raw_source_name	ESMO open
locations[1].landing_page_url	https://pubmed.ncbi.nlm.nih.gov/37119788
locations[2].id	pmh:oai:pubmedcentral.nih.gov:10265597
locations[2].is_oa	True
locations[2].source.id	https://openalex.org/S2764455111
locations[2].source.issn
locations[2].source.type	repository
locations[2].source.is_oa	False
locations[2].source.issn_l
locations[2].source.is_core	False
locations[2].source.is_in_doaj	False
locations[2].source.display_name	PubMed Central
locations[2].source.host_organization	https://openalex.org/I1299303238
locations[2].source.host_organization_name	National Institutes of Health
locations[2].source.host_organization_lineage	https://openalex.org/I1299303238
locations[2].license	cc-by-nc-nd
locations[2].pdf_url	https://pmc.ncbi.nlm.nih.gov/articles/PMC10265597/pdf/main.pdf
locations[2].version	submittedVersion
locations[2].raw_type	Text
locations[2].license_id	https://openalex.org/licenses/cc-by-nc-nd
locations[2].is_accepted	False
locations[2].is_published	False
locations[2].raw_source_name	ESMO Open
locations[2].landing_page_url	https://www.ncbi.nlm.nih.gov/pmc/articles/10265597
indexed_in	crossref, doaj, pubmed
authorships[0].author.id	https://openalex.org/A5076690603
authorships[0].author.orcid	https://orcid.org/0000-0003-4093-2681
authorships[0].author.display_name	Giulia Martini
authorships[0].countries	IT
authorships[0].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[0].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[0].institutions[0].id	https://openalex.org/I197809005
authorships[0].institutions[0].ror	https://ror.org/02kqnpp86
authorships[0].institutions[0].type	education
authorships[0].institutions[0].lineage	https://openalex.org/I197809005
authorships[0].institutions[0].country_code	IT
authorships[0].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[0].author_position	first
authorships[0].raw_author_name	G Martini
authorships[0].is_corresponding	False
authorships[0].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[1].author.id	https://openalex.org/A5036184772
authorships[1].author.orcid	https://orcid.org/0000-0002-7774-3764
authorships[1].author.display_name	Valentina Belli
authorships[1].countries	IT
authorships[1].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[1].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[1].institutions[0].id	https://openalex.org/I197809005
authorships[1].institutions[0].ror	https://ror.org/02kqnpp86
authorships[1].institutions[0].type	education
authorships[1].institutions[0].lineage	https://openalex.org/I197809005
authorships[1].institutions[0].country_code	IT
authorships[1].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[1].author_position	middle
authorships[1].raw_author_name	V Belli
authorships[1].is_corresponding	False
authorships[1].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[2].author.id	https://openalex.org/A5004016643
authorships[2].author.orcid	https://orcid.org/0000-0003-3504-8349
authorships[2].author.display_name	Stefania Napolitano
authorships[2].countries	IT
authorships[2].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[2].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[2].institutions[0].id	https://openalex.org/I197809005
authorships[2].institutions[0].ror	https://ror.org/02kqnpp86
authorships[2].institutions[0].type	education
authorships[2].institutions[0].lineage	https://openalex.org/I197809005
authorships[2].institutions[0].country_code	IT
authorships[2].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[2].author_position	middle
authorships[2].raw_author_name	S Napolitano
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[3].author.id	https://openalex.org/A5069926525
authorships[3].author.orcid	https://orcid.org/0000-0001-5924-4008
authorships[3].author.display_name	Vincenza Ciaramella
authorships[3].countries	IT
authorships[3].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[3].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[3].institutions[0].id	https://openalex.org/I197809005
authorships[3].institutions[0].ror	https://ror.org/02kqnpp86
authorships[3].institutions[0].type	education
authorships[3].institutions[0].lineage	https://openalex.org/I197809005
authorships[3].institutions[0].country_code	IT
authorships[3].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[3].author_position	middle
authorships[3].raw_author_name	V Ciaramella
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[4].author.id	https://openalex.org/A5047539709
authorships[4].author.orcid	https://orcid.org/0000-0003-1826-0305
authorships[4].author.display_name	Davide Ciardiello
authorships[4].countries	IT
authorships[4].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[4].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[4].institutions[0].id	https://openalex.org/I197809005
authorships[4].institutions[0].ror	https://ror.org/02kqnpp86
authorships[4].institutions[0].type	education
authorships[4].institutions[0].lineage	https://openalex.org/I197809005
authorships[4].institutions[0].country_code	IT
authorships[4].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[4].author_position	middle
authorships[4].raw_author_name	D Ciardiello
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[5].author.id	https://openalex.org/A5027111896
authorships[5].author.orcid
authorships[5].author.display_name	A Belli
authorships[5].countries	IT
authorships[5].affiliations[0].institution_ids	https://openalex.org/I4210141868
authorships[5].affiliations[0].raw_affiliation_string	Hepatobiliary Surgical Oncology Unit, Istituto Nazionale Tumori-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione G. Pascale, Napoli.
authorships[5].institutions[0].id	https://openalex.org/I4210141868
authorships[5].institutions[0].ror	https://ror.org/0506y2b23
authorships[5].institutions[0].type	healthcare
authorships[5].institutions[0].lineage	https://openalex.org/I4210141868, https://openalex.org/I4210153126
authorships[5].institutions[0].country_code	IT
authorships[5].institutions[0].display_name	Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
authorships[5].author_position	middle
authorships[5].raw_author_name	A Belli
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	Hepatobiliary Surgical Oncology Unit, Istituto Nazionale Tumori-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione G. Pascale, Napoli.
authorships[6].author.id	https://openalex.org/A5038258515
authorships[6].author.orcid	https://orcid.org/0000-0002-5813-6504
authorships[6].author.display_name	Franco Izzo
authorships[6].countries	IT
authorships[6].affiliations[0].institution_ids	https://openalex.org/I4210141868
authorships[6].affiliations[0].raw_affiliation_string	Hepatobiliary Surgical Oncology Unit, Istituto Nazionale Tumori-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione G. Pascale, Napoli.
authorships[6].institutions[0].id	https://openalex.org/I4210141868
authorships[6].institutions[0].ror	https://ror.org/0506y2b23
authorships[6].institutions[0].type	healthcare
authorships[6].institutions[0].lineage	https://openalex.org/I4210141868, https://openalex.org/I4210153126
authorships[6].institutions[0].country_code	IT
authorships[6].institutions[0].display_name	Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
authorships[6].author_position	middle
authorships[6].raw_author_name	F Izzo
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Hepatobiliary Surgical Oncology Unit, Istituto Nazionale Tumori-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione G. Pascale, Napoli.
authorships[7].author.id	https://openalex.org/A5088304855
authorships[7].author.orcid	https://orcid.org/0000-0001-6188-5664
authorships[7].author.display_name	Antonio Avallone
authorships[7].countries	IT
authorships[7].affiliations[0].institution_ids	https://openalex.org/I4210141868
authorships[7].affiliations[0].raw_affiliation_string	Experimental Clinical Abdominal Oncology Unit, Istituto Nazionale Tumori-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione G. Pascale, Napoli.
authorships[7].institutions[0].id	https://openalex.org/I4210141868
authorships[7].institutions[0].ror	https://ror.org/0506y2b23
authorships[7].institutions[0].type	healthcare
authorships[7].institutions[0].lineage	https://openalex.org/I4210141868, https://openalex.org/I4210153126
authorships[7].institutions[0].country_code	IT
authorships[7].institutions[0].display_name	Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
authorships[7].author_position	middle
authorships[7].raw_author_name	A Avallone
authorships[7].is_corresponding	False
authorships[7].raw_affiliation_strings	Experimental Clinical Abdominal Oncology Unit, Istituto Nazionale Tumori-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione G. Pascale, Napoli.
authorships[8].author.id	https://openalex.org/A5068792216
authorships[8].author.orcid	https://orcid.org/0000-0002-3219-3797
authorships[8].author.display_name	Francesco Selvaggi
authorships[8].countries	IT
authorships[8].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[8].affiliations[0].raw_affiliation_string	Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[8].institutions[0].id	https://openalex.org/I197809005
authorships[8].institutions[0].ror	https://ror.org/02kqnpp86
authorships[8].institutions[0].type	education
authorships[8].institutions[0].lineage	https://openalex.org/I197809005
authorships[8].institutions[0].country_code	IT
authorships[8].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[8].author_position	middle
authorships[8].raw_author_name	F Selvaggi
authorships[8].is_corresponding	False
authorships[8].raw_affiliation_strings	Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[9].author.id	https://openalex.org/A5030199212
authorships[9].author.orcid
authorships[9].author.display_name	F Menegon Tasselli
authorships[9].countries	IT
authorships[9].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[9].affiliations[0].raw_affiliation_string	Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[9].institutions[0].id	https://openalex.org/I197809005
authorships[9].institutions[0].ror	https://ror.org/02kqnpp86
authorships[9].institutions[0].type	education
authorships[9].institutions[0].lineage	https://openalex.org/I197809005
authorships[9].institutions[0].country_code	IT
authorships[9].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[9].author_position	middle
authorships[9].raw_author_name	F Menegon Tasselli
authorships[9].is_corresponding	False
authorships[9].raw_affiliation_strings	Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[10].author.id	https://openalex.org/A5075240224
authorships[10].author.orcid
authorships[10].author.display_name	W Santaniello
authorships[10].countries	IT
authorships[10].affiliations[0].institution_ids	https://openalex.org/I4210087768
authorships[10].affiliations[0].raw_affiliation_string	Hepatobiliary Surgical Oncology Unit, AORN Cardarelli, Naples.
authorships[10].institutions[0].id	https://openalex.org/I4210087768
authorships[10].institutions[0].ror	https://ror.org/003hhqx84
authorships[10].institutions[0].type	healthcare
authorships[10].institutions[0].lineage	https://openalex.org/I4210087768
authorships[10].institutions[0].country_code	IT
authorships[10].institutions[0].display_name	Ospedale Antonio Cardarelli
authorships[10].author_position	middle
authorships[10].raw_author_name	W Santaniello
authorships[10].is_corresponding	False
authorships[10].raw_affiliation_strings	Hepatobiliary Surgical Oncology Unit, AORN Cardarelli, Naples.
authorships[11].author.id	https://openalex.org/A5067376970
authorships[11].author.orcid	https://orcid.org/0000-0002-8340-3184
authorships[11].author.display_name	Renato Franco
authorships[11].countries	IT
authorships[11].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[11].affiliations[0].raw_affiliation_string	Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
authorships[11].institutions[0].id	https://openalex.org/I197809005
authorships[11].institutions[0].ror	https://ror.org/02kqnpp86
authorships[11].institutions[0].type	education
authorships[11].institutions[0].lineage	https://openalex.org/I197809005
authorships[11].institutions[0].country_code	IT
authorships[11].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[11].author_position	middle
authorships[11].raw_author_name	R Franco
authorships[11].is_corresponding	False
authorships[11].raw_affiliation_strings	Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
authorships[12].author.id	https://openalex.org/A5011103296
authorships[12].author.orcid	https://orcid.org/0000-0001-5614-4298
authorships[12].author.display_name	Isabel Puig
authorships[12].countries	ES
authorships[12].affiliations[0].institution_ids	https://openalex.org/I4210151726, https://openalex.org/I4387155398
authorships[12].affiliations[0].raw_affiliation_string	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[12].institutions[0].id	https://openalex.org/I4387155398
authorships[12].institutions[0].ror	https://ror.org/054xx3904
authorships[12].institutions[0].type	healthcare
authorships[12].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[12].institutions[0].country_code
authorships[12].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[12].institutions[1].id	https://openalex.org/I4210151726
authorships[12].institutions[1].ror	https://ror.org/04xezgr31
authorships[12].institutions[1].type	other
authorships[12].institutions[1].lineage	https://openalex.org/I4210102407, https://openalex.org/I4210127641, https://openalex.org/I4210151726, https://openalex.org/I4387153040
authorships[12].institutions[1].country_code	ES
authorships[12].institutions[1].display_name	CIBBIM-Nanomedicine
authorships[12].author_position	middle
authorships[12].raw_author_name	I Puig
authorships[12].is_corresponding	False
authorships[12].raw_affiliation_strings	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[13].author.id	https://openalex.org/A5008603187
authorships[13].author.orcid	https://orcid.org/0000-0003-1792-7390
authorships[13].author.display_name	Lorena Ramírez
authorships[13].countries	ES
authorships[13].affiliations[0].institution_ids	https://openalex.org/I4210151726, https://openalex.org/I4387155398
authorships[13].affiliations[0].raw_affiliation_string	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[13].institutions[0].id	https://openalex.org/I4387155398
authorships[13].institutions[0].ror	https://ror.org/054xx3904
authorships[13].institutions[0].type	healthcare
authorships[13].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[13].institutions[0].country_code
authorships[13].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[13].institutions[1].id	https://openalex.org/I4210151726
authorships[13].institutions[1].ror	https://ror.org/04xezgr31
authorships[13].institutions[1].type	other
authorships[13].institutions[1].lineage	https://openalex.org/I4210102407, https://openalex.org/I4210127641, https://openalex.org/I4210151726, https://openalex.org/I4387153040
authorships[13].institutions[1].country_code	ES
authorships[13].institutions[1].display_name	CIBBIM-Nanomedicine
authorships[13].author_position	middle
authorships[13].raw_author_name	L Ramirez
authorships[13].is_corresponding	False
authorships[13].raw_affiliation_strings	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[14].author.id	https://openalex.org/A5039923734
authorships[14].author.orcid	https://orcid.org/0000-0002-6675-4783
authorships[14].author.display_name	Irene Chicote
authorships[14].countries	ES
authorships[14].affiliations[0].institution_ids	https://openalex.org/I4210151726, https://openalex.org/I4387155398
authorships[14].affiliations[0].raw_affiliation_string	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[14].institutions[0].id	https://openalex.org/I4387155398
authorships[14].institutions[0].ror	https://ror.org/054xx3904
authorships[14].institutions[0].type	healthcare
authorships[14].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[14].institutions[0].country_code
authorships[14].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[14].institutions[1].id	https://openalex.org/I4210151726
authorships[14].institutions[1].ror	https://ror.org/04xezgr31
authorships[14].institutions[1].type	other
authorships[14].institutions[1].lineage	https://openalex.org/I4210102407, https://openalex.org/I4210127641, https://openalex.org/I4210151726, https://openalex.org/I4387153040
authorships[14].institutions[1].country_code	ES
authorships[14].institutions[1].display_name	CIBBIM-Nanomedicine
authorships[14].author_position	middle
authorships[14].raw_author_name	I Chicote
authorships[14].is_corresponding	False
authorships[14].raw_affiliation_strings	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[15].author.id	https://openalex.org/A5028414313
authorships[15].author.orcid	https://orcid.org/0000-0001-5499-6630
authorships[15].author.display_name	Francesco M. Mancuso
authorships[15].affiliations[0].institution_ids	https://openalex.org/I4387155398
authorships[15].affiliations[0].raw_affiliation_string	Cancer Genomics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[15].institutions[0].id	https://openalex.org/I4387155398
authorships[15].institutions[0].ror	https://ror.org/054xx3904
authorships[15].institutions[0].type	healthcare
authorships[15].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[15].institutions[0].country_code
authorships[15].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[15].author_position	middle
authorships[15].raw_author_name	F Mancuso
authorships[15].is_corresponding	False
authorships[15].raw_affiliation_strings	Cancer Genomics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[16].author.id	https://openalex.org/A5027311239
authorships[16].author.orcid	https://orcid.org/0000-0003-1085-8062
authorships[16].author.display_name	Ginevra Caratù
authorships[16].affiliations[0].institution_ids	https://openalex.org/I4387155398
authorships[16].affiliations[0].raw_affiliation_string	Cancer Genomics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[16].institutions[0].id	https://openalex.org/I4387155398
authorships[16].institutions[0].ror	https://ror.org/054xx3904
authorships[16].institutions[0].type	healthcare
authorships[16].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[16].institutions[0].country_code
authorships[16].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[16].author_position	middle
authorships[16].raw_author_name	G Caratu
authorships[16].is_corresponding	False
authorships[16].raw_affiliation_strings	Cancer Genomics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[17].author.id	https://openalex.org/A5027573560
authorships[17].author.orcid
authorships[17].author.display_name	X Serres
authorships[17].countries	ES
authorships[17].affiliations[0].institution_ids	https://openalex.org/I4210127641
authorships[17].affiliations[0].raw_affiliation_string	Department of Interventional Radiology, Hospital Universitari Vall d'Hebron, Barcelona.
authorships[17].institutions[0].id	https://openalex.org/I4210127641
authorships[17].institutions[0].ror	https://ror.org/03ba28x55
authorships[17].institutions[0].type	healthcare
authorships[17].institutions[0].lineage	https://openalex.org/I4210127641
authorships[17].institutions[0].country_code	ES
authorships[17].institutions[0].display_name	Vall d'Hebron Hospital Universitari
authorships[17].author_position	middle
authorships[17].raw_author_name	X Serres
authorships[17].is_corresponding	False
authorships[17].raw_affiliation_strings	Department of Interventional Radiology, Hospital Universitari Vall d'Hebron, Barcelona.
authorships[18].author.id	https://openalex.org/A5042601272
authorships[18].author.orcid	https://orcid.org/0000-0003-1630-9988
authorships[18].author.display_name	Roberta Fasani
authorships[18].countries	US
authorships[18].affiliations[0].institution_ids	https://openalex.org/I4210150208, https://openalex.org/I4387155398
authorships[18].affiliations[0].raw_affiliation_string	Molecular Oncology Lab, Vall d'Hebron Institute of Oncology, Barcelona.
authorships[18].institutions[0].id	https://openalex.org/I4387155398
authorships[18].institutions[0].ror	https://ror.org/054xx3904
authorships[18].institutions[0].type	healthcare
authorships[18].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[18].institutions[0].country_code
authorships[18].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[18].institutions[1].id	https://openalex.org/I4210150208
authorships[18].institutions[1].ror	https://ror.org/04rtkc841
authorships[18].institutions[1].type	company
authorships[18].institutions[1].lineage	https://openalex.org/I4210150208
authorships[18].institutions[1].country_code	US
authorships[18].institutions[1].display_name	Molecular Oncology (United States)
authorships[18].author_position	middle
authorships[18].raw_author_name	R Fasani
authorships[18].is_corresponding	False
authorships[18].raw_affiliation_strings	Molecular Oncology Lab, Vall d'Hebron Institute of Oncology, Barcelona.
authorships[19].author.id	https://openalex.org/A5020391246
authorships[19].author.orcid	https://orcid.org/0000-0002-2576-1776
authorships[19].author.display_name	José Jimenez
authorships[19].countries	US
authorships[19].affiliations[0].institution_ids	https://openalex.org/I4210150208, https://openalex.org/I4387155398
authorships[19].affiliations[0].raw_affiliation_string	Molecular Oncology Lab, Vall d'Hebron Institute of Oncology, Barcelona.
authorships[19].institutions[0].id	https://openalex.org/I4387155398
authorships[19].institutions[0].ror	https://ror.org/054xx3904
authorships[19].institutions[0].type	healthcare
authorships[19].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[19].institutions[0].country_code
authorships[19].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[19].institutions[1].id	https://openalex.org/I4210150208
authorships[19].institutions[1].ror	https://ror.org/04rtkc841
authorships[19].institutions[1].type	company
authorships[19].institutions[1].lineage	https://openalex.org/I4210150208
authorships[19].institutions[1].country_code	US
authorships[19].institutions[1].display_name	Molecular Oncology (United States)
authorships[19].author_position	middle
authorships[19].raw_author_name	J Jimenez
authorships[19].is_corresponding	False
authorships[19].raw_affiliation_strings	Molecular Oncology Lab, Vall d'Hebron Institute of Oncology, Barcelona.
authorships[20].author.id	https://openalex.org/A5074495046
authorships[20].author.orcid	https://orcid.org/0000-0002-8137-5415
authorships[20].author.display_name	Javier Ros
authorships[20].affiliations[0].raw_affiliation_string	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[20].author_position	middle
authorships[20].raw_author_name	J Ros
authorships[20].is_corresponding	False
authorships[20].raw_affiliation_strings	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[21].author.id	https://openalex.org/A5014230558
authorships[21].author.orcid	https://orcid.org/0000-0002-3500-9641
authorships[21].author.display_name	Iosune Baraibar
authorships[21].affiliations[0].raw_affiliation_string	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[21].author_position	middle
authorships[21].raw_author_name	I Baraibar
authorships[21].is_corresponding	False
authorships[21].raw_affiliation_strings	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[22].author.id	https://openalex.org/A5112355522
authorships[22].author.orcid
authorships[22].author.display_name	Nuria Mulet
authorships[22].countries	ES
authorships[22].affiliations[0].institution_ids	https://openalex.org/I4210107147
authorships[22].affiliations[0].raw_affiliation_string	B-ARGO Badalona Applied Research Group in Oncology, Catalan Institute of Oncology, Badalona.
authorships[22].institutions[0].id	https://openalex.org/I4210107147
authorships[22].institutions[0].ror	https://ror.org/01j1eb875
authorships[22].institutions[0].type	government
authorships[22].institutions[0].lineage	https://openalex.org/I4210107147
authorships[22].institutions[0].country_code	ES
authorships[22].institutions[0].display_name	Institut Català d'Oncologia
authorships[22].author_position	middle
authorships[22].raw_author_name	N Mulet
authorships[22].is_corresponding	False
authorships[22].raw_affiliation_strings	B-ARGO Badalona Applied Research Group in Oncology, Catalan Institute of Oncology, Badalona.
authorships[23].author.id	https://openalex.org/A5032164411
authorships[23].author.orcid
authorships[23].author.display_name	Carminia Maria Della Corte
authorships[23].countries	IT
authorships[23].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[23].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[23].institutions[0].id	https://openalex.org/I197809005
authorships[23].institutions[0].ror	https://ror.org/02kqnpp86
authorships[23].institutions[0].type	education
authorships[23].institutions[0].lineage	https://openalex.org/I197809005
authorships[23].institutions[0].country_code	IT
authorships[23].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[23].author_position	middle
authorships[23].raw_author_name	C M Della Corte
authorships[23].is_corresponding	False
authorships[23].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[24].author.id	https://openalex.org/A5048947412
authorships[24].author.orcid
authorships[24].author.display_name	Teresa Troiani
authorships[24].countries	IT
authorships[24].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[24].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[24].institutions[0].id	https://openalex.org/I197809005
authorships[24].institutions[0].ror	https://ror.org/02kqnpp86
authorships[24].institutions[0].type	education
authorships[24].institutions[0].lineage	https://openalex.org/I197809005
authorships[24].institutions[0].country_code	IT
authorships[24].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[24].author_position	middle
authorships[24].raw_author_name	T Troiani
authorships[24].is_corresponding	False
authorships[24].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[25].author.id	https://openalex.org/A5071876778
authorships[25].author.orcid	https://orcid.org/0000-0003-2888-6512
authorships[25].author.display_name	Ana Vivancos
authorships[25].affiliations[0].institution_ids	https://openalex.org/I4387155398
authorships[25].affiliations[0].raw_affiliation_string	Cancer Genomics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[25].institutions[0].id	https://openalex.org/I4387155398
authorships[25].institutions[0].ror	https://ror.org/054xx3904
authorships[25].institutions[0].type	healthcare
authorships[25].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[25].institutions[0].country_code
authorships[25].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[25].author_position	middle
authorships[25].raw_author_name	A Vivancos
authorships[25].is_corresponding	False
authorships[25].raw_affiliation_strings	Cancer Genomics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[26].author.id	https://openalex.org/A5087015760
authorships[26].author.orcid	https://orcid.org/0000-0001-5997-318X
authorships[26].author.display_name	Rodrigo Dienstmann
authorships[26].countries	ES
authorships[26].affiliations[0].institution_ids	https://openalex.org/I4210127641, https://openalex.org/I4387155398
authorships[26].affiliations[0].raw_affiliation_string	Oncology Data Science, Vall d'Hebron Institute of Oncology, Barcelona.
authorships[26].institutions[0].id	https://openalex.org/I4387155398
authorships[26].institutions[0].ror	https://ror.org/054xx3904
authorships[26].institutions[0].type	healthcare
authorships[26].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[26].institutions[0].country_code
authorships[26].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[26].institutions[1].id	https://openalex.org/I4210127641
authorships[26].institutions[1].ror	https://ror.org/03ba28x55
authorships[26].institutions[1].type	healthcare
authorships[26].institutions[1].lineage	https://openalex.org/I4210127641
authorships[26].institutions[1].country_code	ES
authorships[26].institutions[1].display_name	Vall d'Hebron Hospital Universitari
authorships[26].author_position	middle
authorships[26].raw_author_name	R Dienstmann
authorships[26].is_corresponding	False
authorships[26].raw_affiliation_strings	Oncology Data Science, Vall d'Hebron Institute of Oncology, Barcelona.
authorships[27].author.id	https://openalex.org/A5030657436
authorships[27].author.orcid	https://orcid.org/0000-0002-4653-6324
authorships[27].author.display_name	Elena Élez
authorships[27].affiliations[0].raw_affiliation_string	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[27].author_position	middle
authorships[27].raw_author_name	E Elez
authorships[27].is_corresponding	False
authorships[27].raw_affiliation_strings	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[28].author.id	https://openalex.org/A5091638379
authorships[28].author.orcid	https://orcid.org/0000-0002-9823-5638
authorships[28].author.display_name	Héctor G. Pálmer
authorships[28].countries	ES
authorships[28].affiliations[0].institution_ids	https://openalex.org/I4210151726, https://openalex.org/I4387155398
authorships[28].affiliations[0].raw_affiliation_string	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[28].institutions[0].id	https://openalex.org/I4387155398
authorships[28].institutions[0].ror	https://ror.org/054xx3904
authorships[28].institutions[0].type	healthcare
authorships[28].institutions[0].lineage	https://openalex.org/I4387153040, https://openalex.org/I4387155398
authorships[28].institutions[0].country_code
authorships[28].institutions[0].display_name	Vall d'Hebron Institute of Oncology
authorships[28].institutions[1].id	https://openalex.org/I4210151726
authorships[28].institutions[1].ror	https://ror.org/04xezgr31
authorships[28].institutions[1].type	other
authorships[28].institutions[1].lineage	https://openalex.org/I4210102407, https://openalex.org/I4210127641, https://openalex.org/I4210151726, https://openalex.org/I4387153040
authorships[28].institutions[1].country_code	ES
authorships[28].institutions[1].display_name	CIBBIM-Nanomedicine
authorships[28].author_position	middle
authorships[28].raw_author_name	H G Palmer
authorships[28].is_corresponding	False
authorships[28].raw_affiliation_strings	Translational Program, Stem Cells and Cancer Laboratory, Vall D'Hebron Institute of Oncology (VHIO), Barcelona.
authorships[29].author.id	https://openalex.org/A5015190461
authorships[29].author.orcid	https://orcid.org/0000-0002-2495-8139
authorships[29].author.display_name	Josep Tabernero
authorships[29].affiliations[0].raw_affiliation_string	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[29].author_position	middle
authorships[29].raw_author_name	J Tabernero
authorships[29].is_corresponding	False
authorships[29].raw_affiliation_strings	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona.
authorships[30].author.id	https://openalex.org/A5074105754
authorships[30].author.orcid	https://orcid.org/0000-0002-7108-0971
authorships[30].author.display_name	Erika Martinelli
authorships[30].countries	IT
authorships[30].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[30].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[30].institutions[0].id	https://openalex.org/I197809005
authorships[30].institutions[0].ror	https://ror.org/02kqnpp86
authorships[30].institutions[0].type	education
authorships[30].institutions[0].lineage	https://openalex.org/I197809005
authorships[30].institutions[0].country_code	IT
authorships[30].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[30].author_position	middle
authorships[30].raw_author_name	E Martinelli
authorships[30].is_corresponding	False
authorships[30].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[31].author.id	https://openalex.org/A5043177546
authorships[31].author.orcid	https://orcid.org/0000-0002-4661-5540
authorships[31].author.display_name	Fortunato Ciardiello
authorships[31].countries	IT
authorships[31].affiliations[0].institution_ids	https://openalex.org/I197809005
authorships[31].affiliations[0].raw_affiliation_string	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[31].institutions[0].id	https://openalex.org/I197809005
authorships[31].institutions[0].ror	https://ror.org/02kqnpp86
authorships[31].institutions[0].type	education
authorships[31].institutions[0].lineage	https://openalex.org/I197809005
authorships[31].institutions[0].country_code	IT
authorships[31].institutions[0].display_name	University of Campania "Luigi Vanvitelli"
authorships[31].author_position	middle
authorships[31].raw_author_name	F Ciardiello
authorships[31].is_corresponding	False
authorships[31].raw_affiliation_strings	Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples.
authorships[32].author.id	https://openalex.org/A5053880366
authorships[32].author.orcid	https://orcid.org/0000-0002-1487-7108
authorships[32].author.display_name	Guillem Argilés
authorships[32].countries	ES, US
authorships[32].affiliations[0].institution_ids	https://openalex.org/I123044942, https://openalex.org/I1334819555
authorships[32].affiliations[0].raw_affiliation_string	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona; Universitat Autònoma de Barcelona, Barcelona, Spain; Memorial Sloan Kettering Cancer Center, New York, USA. Electronic address: [email protected].
authorships[32].institutions[0].id	https://openalex.org/I123044942
authorships[32].institutions[0].ror	https://ror.org/052g8jq94
authorships[32].institutions[0].type	education
authorships[32].institutions[0].lineage	https://openalex.org/I123044942
authorships[32].institutions[0].country_code	ES
authorships[32].institutions[0].display_name	Universitat Autònoma de Barcelona
authorships[32].institutions[1].id	https://openalex.org/I1334819555
authorships[32].institutions[1].ror	https://ror.org/02yrq0923
authorships[32].institutions[1].type	healthcare
authorships[32].institutions[1].lineage	https://openalex.org/I1334819555
authorships[32].institutions[1].country_code	US
authorships[32].institutions[1].display_name	Memorial Sloan Kettering Cancer Center
authorships[32].author_position	last
authorships[32].raw_author_name	G Argilés
authorships[32].is_corresponding	False
authorships[32].raw_affiliation_strings	Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), Barcelona; Universitat Autònoma de Barcelona, Barcelona, Spain; Memorial Sloan Kettering Cancer Center, New York, USA. Electronic address: [email protected].
has_content.pdf	False
has_content.grobid_xml	False
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://doi.org/10.1016/j.esmoop.2023.101198
open_access.oa_status	gold
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	Establishment of patient-derived tumor organoids to functionally inform treatment decisions in metastatic colorectal cancer
has_fulltext	False
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T10336
primary_topic.field.id	https://openalex.org/fields/27
primary_topic.field.display_name	Medicine
primary_topic.score	0.9994999766349792
primary_topic.domain.id	https://openalex.org/domains/4
primary_topic.domain.display_name	Health Sciences
primary_topic.subfield.id	https://openalex.org/subfields/2730
primary_topic.subfield.display_name	Oncology
primary_topic.display_name	Cancer Cells and Metastasis
related_works	https://openalex.org/W2809146871, https://openalex.org/W2235788479, https://openalex.org/W3110357236, https://openalex.org/W2037039278, https://openalex.org/W2058051426, https://openalex.org/W2027242489, https://openalex.org/W2016705530, https://openalex.org/W2138294834, https://openalex.org/W2136984368, https://openalex.org/W3140349894
cited_by_count	28
counts_by_year[0].year	2025
counts_by_year[0].cited_by_count	12
counts_by_year[1].year	2024
counts_by_year[1].cited_by_count	10
counts_by_year[2].year	2023
counts_by_year[2].cited_by_count	6
locations_count	3
best_oa_location.id	doi:10.1016/j.esmoop.2023.101198
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S4210217024
best_oa_location.source.issn	2059-7029
best_oa_location.source.type	journal
best_oa_location.source.is_oa	True
best_oa_location.source.issn_l	2059-7029
best_oa_location.source.is_core	True
best_oa_location.source.is_in_doaj	True
best_oa_location.source.display_name	ESMO Open
best_oa_location.source.host_organization	https://openalex.org/P4310320990
best_oa_location.source.host_organization_name	Elsevier BV
best_oa_location.source.host_organization_lineage	https://openalex.org/P4310320990
best_oa_location.source.host_organization_lineage_names	Elsevier BV
best_oa_location.license
best_oa_location.pdf_url
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	ESMO Open
best_oa_location.landing_page_url	https://doi.org/10.1016/j.esmoop.2023.101198
primary_location.id	doi:10.1016/j.esmoop.2023.101198
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S4210217024
primary_location.source.issn	2059-7029
primary_location.source.type	journal
primary_location.source.is_oa	True
primary_location.source.issn_l	2059-7029
primary_location.source.is_core	True
primary_location.source.is_in_doaj	True
primary_location.source.display_name	ESMO Open
primary_location.source.host_organization	https://openalex.org/P4310320990
primary_location.source.host_organization_name	Elsevier BV
primary_location.source.host_organization_lineage	https://openalex.org/P4310320990
primary_location.source.host_organization_lineage_names	Elsevier BV
primary_location.license
primary_location.pdf_url
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	ESMO Open
primary_location.landing_page_url	https://doi.org/10.1016/j.esmoop.2023.101198
publication_date	2023-04-27
publication_year	2023
referenced_works	https://openalex.org/W2102354469, https://openalex.org/W4224880107, https://openalex.org/W1934094702, https://openalex.org/W3099376746, https://openalex.org/W2074175804, https://openalex.org/W2035252444, https://openalex.org/W2002513358, https://openalex.org/W2789773980, https://openalex.org/W2951426376, https://openalex.org/W1741548448, https://openalex.org/W2798041799, https://openalex.org/W2788735115, https://openalex.org/W2887223472, https://openalex.org/W1965157206, https://openalex.org/W3210011078, https://openalex.org/W3215141374, https://openalex.org/W6798600767, https://openalex.org/W4223999681, https://openalex.org/W3178562850, https://openalex.org/W3184751888
referenced_works_count	20
abstract_inverted_index.a	3, 10
abstract_inverted_index.as	2
abstract_inverted_index.to	14, 28
abstract_inverted_index.we	5
abstract_inverted_index.CRC	1
abstract_inverted_index.and	8, 33
abstract_inverted_index.are	26
abstract_inverted_index.for	38
abstract_inverted_index.have	6
abstract_inverted_index.mCRC	39
abstract_inverted_index.with	19
abstract_inverted_index.Using	0
abstract_inverted_index.data.	21
abstract_inverted_index.rates	32
abstract_inverted_index.inform	16
abstract_inverted_index.larger	24
abstract_inverted_index.model,	4
abstract_inverted_index.needed	27
abstract_inverted_index.further	23
abstract_inverted_index.improve	29
abstract_inverted_index.propose	34
abstract_inverted_index.success	31
abstract_inverted_index.analyses	25
abstract_inverted_index.clinical	17
abstract_inverted_index.designed	7
abstract_inverted_index.suitable	35
abstract_inverted_index.decisions	18
abstract_inverted_index.patients.	40
abstract_inverted_index.treatment	36
abstract_inverted_index.validated	9
abstract_inverted_index.applicable	12
abstract_inverted_index.clinically	11
abstract_inverted_index.functional	20
abstract_inverted_index.strategies	37
abstract_inverted_index.methodology	13, 30
abstract_inverted_index.potentially	15
abstract_inverted_index.Undoubtedly,	22
cited_by_percentile_year.max	99
cited_by_percentile_year.min	98
countries_distinct_count	3
institutions_distinct_count	33
sustainable_development_goals[0].id	https://metadata.un.org/sdg/3
sustainable_development_goals[0].score	0.8600000143051147
sustainable_development_goals[0].display_name	Good health and well-being
citation_normalized_percentile.value	0.97858736
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	True