Etiologies and characteristics of refractory status epilepticus cases in different areas of the world: Results from a global audit Article Swipe
Monica Ferlisi
,
Sara E. Hocker
,
Eugen Trinka
,
Simon Shorvon
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1111/epi.14496
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1111/epi.14496
Summary To describe the demographics, etiologies, types of status epilepticus ( SE ), and outcomes in people with refractory and super‐refractory SE from around the world, we prospectively collected cases of refractory SE ( RSE ) treated with continuous intravenous anesthetic drugs in an intensive care unit setting through online questionnaires using “active surveillance.” We collected information about 776 cases of RSE in 50 countries over 4 years. Control of SE was achieved in 74% of the cases. Neurologic outcomes were poor in 41% of patients, and 24% died. Good outcome was associated with younger age and a history of epilepsy. Etiology strongly influenced the outcome. Patients from Asia were younger, more frequently presented with convulsive SE , and were more frequently affected by infectious etiologies when compared with patients from Europe and the Americas. Despite these differences, outcomes were similar in all countries. Demographics of patients with RSE in a global audit are similar to those in prior single center series, providing evidence of generalizability of those studies. Important differences exist among patients with RSE from different regions of the world, but these do not seem to significantly influence patient outcomes.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/epi.14496
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/epi.14496
- OA Status
- bronze
- Cited By
- 29
- References
- 19
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2889433928
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2889433928Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/epi.14496Digital Object Identifier
- Title
-
Etiologies and characteristics of refractory status epilepticus cases in different areas of the world: Results from a global auditWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2018Year of publication
- Publication date
-
2018-08-29Full publication date if available
- Authors
-
Monica Ferlisi, Sara E. Hocker, Eugen Trinka, Simon ShorvonList of authors in order
- Landing page
-
https://doi.org/10.1111/epi.14496Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/epi.14496Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/epi.14496Direct OA link when available
- Concepts
-
Etiology, Medicine, Demographics, Refractory (planetary science), Pediatrics, Status epilepticus, Audit, Generalizability theory, Epilepsy, Internal medicine, Psychiatry, Demography, Psychology, Economics, Physics, Astrobiology, Sociology, Developmental psychology, ManagementTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
29Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4, 2024: 5, 2023: 4, 2022: 3, 2021: 7Per-year citation counts (last 5 years)
- References (count)
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19Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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