Evaluación de la pentafecta en pacientes con cáncer de próstata de alto y muy alto riesgo: comparación entre prostatectomía radical laparoscópica y prostatectomía abierta Article Swipe
André Sealhenry Izunza Laisequilla
,
Alsino Ochoa Sánchez
,
Eduardo Puga Ortega
,
Arnulfo L'Gamiz Moreno
,
Christian Vázquez Niño
,
David Isaias Gaytan-Benitez
,
Alvaro Reyes-Aquart
,
Daniel Castro-Fletes
,
Immer Noyola-Ávila
,
Ana Karla Leal-Monarres
,
Patricia Canto
,
André Sealhenry Izunza Laisequilla
,
Alsino Ochoa Sánchez
,
Eduardo Puga Ortega
,
Arnulfo L'Gamiz Moreno
,
Christian Vázquez Niño
,
David Isaias Gaytan-Benitez
,
Alvaro Reyes-Aquart
,
Daniel Castro-Fletes
,
Immer Noyola-Ávila
,
Ana Karla Leal-Monarres
,
Patricia Canto
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.48193/rjz6ss85
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.48193/rjz6ss85
Introduction: prostate cancer (PCa) is the most frequently diagnosed malignancy in men worldwide. Approximately 15 % of cases present as high or very high risk, for which the optimal surgical approach remains controversial. The pentafecta has been proposed as a key indicator of surgical success, integrating oncological and functional outcomes. This study aimed to compare 12-month pentafecta outcomes between open radical prostatectomy (ORP) and laparoscopic radical prostatectomy (LRP) in patients with high and very high-risk PCa. Material and methods: a retrospective observational study was conducted from 2021 to 2024, including 25 patients with localized high or very high-risk PCa who underwent ORP or LRP with extended pelvic lymphadenectomy. Clinical, pathological, and functional variables were analyzed. Comparisons were made using Chi-square, Student’s t-test, or Mann-Whitney U test, according to data distribution. A p-value < 0.05 was considered statistically significant. Results: of the 25 patients, 12 underwent ORP and 13 underwent LRP. The overall pentafecta rate was 36 %. ORP showed a higher rate (50 %) compared to LRP (23 %) (p=0.061). ORP was associated with better biochemical control (p=0.023), fewer perioperative complications (p=0.054), and better erectile function outcomes (p=0.005). Urinary continence rates were similar between groups (p=0.317). Conclusions: we did not find statistically significant differences in the global pentafecta evaluation; however, the ORP showed important clinical differences in comparison to LRP.
Related Topics
Concepts
Medicine
Prostatectomy
Laparoscopic radical prostatectomy
Malignancy
Erectile function
Perioperative
Urology
Urinary continence
Gynecology
Retrospective cohort study
Prostate cancer
Erectile dysfunction
Surgery
Observational study
Urinary system
Urinary incontinence
General surgery
Prostate
Radical surgery
Genitourinary system
Sexual function
Cancer
Laparoscopic surgery
Metadata
- Type
- article
- Landing Page
- https://doi.org/10.48193/rjz6ss85
- https://mail.revistamexicanadeurologia.org.mx/index.php/rmu/article/download/1283/1586
- OA Status
- diamond
- OpenAlex ID
- https://openalex.org/W7106544813
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W7106544813Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.48193/rjz6ss85Digital Object Identifier
- Title
-
Evaluación de la pentafecta en pacientes con cáncer de próstata de alto y muy alto riesgo: comparación entre prostatectomía radical laparoscópica y prostatectomía abiertaWork title
- Type
-
articleOpenAlex work type
- Publication year
-
2025Year of publication
- Publication date
-
2025-11-24Full publication date if available
- Authors
-
André Sealhenry Izunza Laisequilla, Alsino Ochoa Sánchez, Eduardo Puga Ortega, Arnulfo L'Gamiz Moreno, Christian Vázquez Niño, David Isaias Gaytan-Benitez, Alvaro Reyes-Aquart, Daniel Castro-Fletes, Immer Noyola-Ávila, Ana Karla Leal-Monarres, Patricia Canto, André Sealhenry Izunza Laisequilla, Alsino Ochoa Sánchez, Eduardo Puga Ortega, Arnulfo L'Gamiz Moreno, Christian Vázquez Niño, David Isaias Gaytan-Benitez, Alvaro Reyes-Aquart, Daniel Castro-Fletes, Immer Noyola-Ávila, Ana Karla Leal-Monarres, Patricia CantoList of authors in order
- Landing page
-
https://doi.org/10.48193/rjz6ss85Publisher landing page
- PDF URL
-
https://mail.revistamexicanadeurologia.org.mx/index.php/rmu/article/download/1283/1586Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
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https://mail.revistamexicanadeurologia.org.mx/index.php/rmu/article/download/1283/1586Direct OA link when available
- Concepts
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Medicine, Prostatectomy, Laparoscopic radical prostatectomy, Malignancy, Erectile function, Perioperative, Urology, Urinary continence, Gynecology, Retrospective cohort study, Prostate cancer, Erectile dysfunction, Surgery, Observational study, Urinary system, Urinary incontinence, General surgery, Prostate, Radical surgery, Genitourinary system, Sexual function, Cancer, Laparoscopic surgeryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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