Evaluation of a new point-of-care testing for creatinine and urea measurement Article Swipe
YOU?
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· 2021
· Open Access
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· DOI: https://doi.org/10.1080/00365513.2021.1914344
Point of care testing makes it possible to obtain results in an extremely short time. Recently, radiometer has expanded the panel of tests available on its ABL90 FLEX PLUS blood gas analyzer (ABL90) by adding urea and creatinine. The aim of this study was to verify the performance of these new parameters. This included assessment of imprecision, linearity, accuracy by comparison with central laboratory standard assays and interferences. In addition, clinical utility in a dialysis center was evaluated. Within-lab coefficients of variation were close to 2%. The mean and limits of agreement (mean ± 1.96 SD) of the difference between ABL90 and Roche enzymatic assays on cobas 8000 were 0.5 (from -1.4 to 2.3) mmol/L and -0.9 (from -19.5 to 17.8) µmol/L for urea and creatinine, respectively. The ABL90 enzymatic urea and creatinine assays met the acceptance criteria based on biological variation for imprecision and showed good agreement with central laboratory. The two assays were unaffected by hematocrit variation between 20 and 70%, hemolysis and icterus interferences. It should be noted that the relationship between lab methods and ABL90 was conserved even for high pre-dialysis values allowing easy access to dialysis adequacy parameters (Kt/V) and muscle mass evaluation (creatinine index). Rapid measurement of creatinine and urea using whole blood specimens on ABL90 appears as a fast and convenient method. Analytical performances were in accordance with our expectations without any significant interferences by hemolysis or icterus.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1080/00365513.2021.1914344
- OA Status
- green
- Cited By
- 9
- References
- 39
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3158310537
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3158310537Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1080/00365513.2021.1914344Digital Object Identifier
- Title
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Evaluation of a new point-of-care testing for creatinine and urea measurementWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-04-28Full publication date if available
- Authors
-
Anne‐Sophie Bargnoux, Nils Kuster, Thibault Sutra, Laëtitia Laroche, A. Rodríguez, Marion Moréna, Leïla Chénine, Lotfi Chalabi, Anne‐Marie Dupuy, Stéphanie Badiou, Jean‐Paul CristolList of authors in order
- Landing page
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https://doi.org/10.1080/00365513.2021.1914344Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
- OA URL
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https://hal.science/hal-03211936Direct OA link when available
- Concepts
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Creatinine, Hemolysis, Urea, Hematocrit, Dialysis, Point of care, Medicine, Urology, Point-of-care testing, Chemistry, Chromatography, Internal medicine, Biochemistry, PathologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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9Total citation count in OpenAlex
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2025: 1, 2024: 2, 2023: 4, 2022: 2Per-year citation counts (last 5 years)
- References (count)
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39Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.its | 25 |
| abstract_inverted_index.lab | 175 |
| abstract_inverted_index.met | 134 |
| abstract_inverted_index.new | 50 |
| abstract_inverted_index.our | 225 |
| abstract_inverted_index.the | 19, 46, 97, 135, 172 |
| abstract_inverted_index.two | 152 |
| abstract_inverted_index.was | 43, 76, 179 |
| abstract_inverted_index.-0.9 | 116 |
| abstract_inverted_index.-1.4 | 111 |
| abstract_inverted_index.1.96 | 94 |
| abstract_inverted_index.2.3) | 113 |
| abstract_inverted_index.70%, | 162 |
| abstract_inverted_index.8000 | 107 |
| abstract_inverted_index.FLEX | 27 |
| abstract_inverted_index.PLUS | 28 |
| abstract_inverted_index.This | 52 |
| abstract_inverted_index.care | 2 |
| abstract_inverted_index.easy | 187 |
| abstract_inverted_index.even | 181 |
| abstract_inverted_index.fast | 215 |
| abstract_inverted_index.good | 146 |
| abstract_inverted_index.high | 183 |
| abstract_inverted_index.mass | 196 |
| abstract_inverted_index.mean | 87 |
| abstract_inverted_index.that | 171 |
| abstract_inverted_index.this | 41 |
| abstract_inverted_index.urea | 35, 123, 130, 205 |
| abstract_inverted_index.were | 82, 108, 154, 221 |
| abstract_inverted_index.with | 61, 148, 224 |
| abstract_inverted_index.(from | 110, 117 |
| abstract_inverted_index.(mean | 92 |
| abstract_inverted_index.-19.5 | 118 |
| abstract_inverted_index.17.8) | 120 |
| abstract_inverted_index.ABL90 | 26, 100, 128, 178, 211 |
| abstract_inverted_index.Point | 0 |
| abstract_inverted_index.Rapid | 200 |
| abstract_inverted_index.Roche | 102 |
| abstract_inverted_index.based | 138 |
| abstract_inverted_index.blood | 29, 208 |
| abstract_inverted_index.close | 83 |
| abstract_inverted_index.cobas | 106 |
| abstract_inverted_index.makes | 4 |
| abstract_inverted_index.noted | 170 |
| abstract_inverted_index.panel | 20 |
| abstract_inverted_index.short | 13 |
| abstract_inverted_index.study | 42 |
| abstract_inverted_index.tests | 22 |
| abstract_inverted_index.these | 49 |
| abstract_inverted_index.time. | 14 |
| abstract_inverted_index.using | 206 |
| abstract_inverted_index.whole | 207 |
| abstract_inverted_index.access | 188 |
| abstract_inverted_index.adding | 34 |
| abstract_inverted_index.assays | 65, 104, 133, 153 |
| abstract_inverted_index.center | 75 |
| abstract_inverted_index.limits | 89 |
| abstract_inverted_index.mmol/L | 114 |
| abstract_inverted_index.muscle | 195 |
| abstract_inverted_index.obtain | 8 |
| abstract_inverted_index.should | 168 |
| abstract_inverted_index.showed | 145 |
| abstract_inverted_index.values | 185 |
| abstract_inverted_index.verify | 45 |
| abstract_inverted_index.(ABL90) | 32 |
| abstract_inverted_index.appears | 212 |
| abstract_inverted_index.between | 99, 159, 174 |
| abstract_inverted_index.central | 62, 149 |
| abstract_inverted_index.icterus | 165 |
| abstract_inverted_index.index). | 199 |
| abstract_inverted_index.method. | 218 |
| abstract_inverted_index.methods | 176 |
| abstract_inverted_index.results | 9 |
| abstract_inverted_index.testing | 3 |
| abstract_inverted_index.utility | 71 |
| abstract_inverted_index.without | 227 |
| abstract_inverted_index.µmol/L | 121 |
| abstract_inverted_index.accuracy | 58 |
| abstract_inverted_index.adequacy | 191 |
| abstract_inverted_index.allowing | 186 |
| abstract_inverted_index.analyzer | 31 |
| abstract_inverted_index.clinical | 70 |
| abstract_inverted_index.criteria | 137 |
| abstract_inverted_index.dialysis | 74, 190 |
| abstract_inverted_index.expanded | 18 |
| abstract_inverted_index.icterus. | 234 |
| abstract_inverted_index.included | 53 |
| abstract_inverted_index.possible | 6 |
| abstract_inverted_index.standard | 64 |
| abstract_inverted_index.Recently, | 15 |
| abstract_inverted_index.addition, | 69 |
| abstract_inverted_index.agreement | 91, 147 |
| abstract_inverted_index.available | 23 |
| abstract_inverted_index.conserved | 180 |
| abstract_inverted_index.enzymatic | 103, 129 |
| abstract_inverted_index.extremely | 12 |
| abstract_inverted_index.hemolysis | 163, 232 |
| abstract_inverted_index.specimens | 209 |
| abstract_inverted_index.variation | 81, 141, 158 |
| abstract_inverted_index.Analytical | 219 |
| abstract_inverted_index.Within-lab | 78 |
| abstract_inverted_index.acceptance | 136 |
| abstract_inverted_index.accordance | 223 |
| abstract_inverted_index.assessment | 54 |
| abstract_inverted_index.biological | 140 |
| abstract_inverted_index.comparison | 60 |
| abstract_inverted_index.convenient | 217 |
| abstract_inverted_index.creatinine | 132, 203 |
| abstract_inverted_index.difference | 98 |
| abstract_inverted_index.evaluated. | 77 |
| abstract_inverted_index.evaluation | 197 |
| abstract_inverted_index.hematocrit | 157 |
| abstract_inverted_index.laboratory | 63 |
| abstract_inverted_index.linearity, | 57 |
| abstract_inverted_index.parameters | 192 |
| abstract_inverted_index.radiometer | 16 |
| abstract_inverted_index.unaffected | 155 |
| abstract_inverted_index.(creatinine | 198 |
| abstract_inverted_index.creatinine, | 125 |
| abstract_inverted_index.creatinine. | 37 |
| abstract_inverted_index.imprecision | 143 |
| abstract_inverted_index.laboratory. | 150 |
| abstract_inverted_index.measurement | 201 |
| abstract_inverted_index.parameters. | 51 |
| abstract_inverted_index.performance | 47 |
| abstract_inverted_index.significant | 229 |
| abstract_inverted_index.coefficients | 79 |
| abstract_inverted_index.expectations | 226 |
| abstract_inverted_index.imprecision, | 56 |
| abstract_inverted_index.performances | 220 |
| abstract_inverted_index.pre-dialysis | 184 |
| abstract_inverted_index.relationship | 173 |
| abstract_inverted_index.interferences | 230 |
| abstract_inverted_index.respectively. | 126 |
| abstract_inverted_index.interferences. | 67, 166 |
| abstract_inverted_index.(<i>Kt</i>/<i>V</i>) | 193 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 91 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 11 |
| citation_normalized_percentile.value | 0.74015771 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |