Evaluation of encapsulated catechin in chitosan- sodium tripolyphosphate nanoparticle Article Swipe

View

Related Concepts

Chitosan Nanoparticle Catechin Chemistry Particle size Drug delivery Sodium Antioxidant Nuclear chemistry Polyphenol Chromatography Nanotechnology Organic chemistry Materials science Physical chemistry

Ravi Shankar Kumar Mandal , Sonam Bhatt , Jithin Mv , Aishwerya Lekshman , R. Raguvaran , DB Mondal ·

YOU? · · 2019 · Open Access · · OA: W3082499857

In present study assessment of suitable drug delivery system for catechin using polymer of chitosan and its in vitro antioxidant were studied. Chitosan-tripolyphosphate forms ionic cross linkage. Particle size analysis revealed blank chitosan nanoparticle of size 392 nm and catechin loaded chitosan nanoparticle of size 324.4 nm. Encapsulation efficiency 69.17% and drug loading capacity 43.46% was recorded. In vitro release study revealed 9.74% release in simulated gastric fluid (SGF) and 23.58% release of catechin in simulated intestinal fluid (SIF).