Evaluation of immunomorphological patterns of cervical lymph nodes in oral squamous cell carcinoma Article Swipe
Hyandavi Balla
,
Divya Uppala
,
Sumit Majumdar
,
Sreekanth Kotina
,
Sravya Kodati
,
Madhurya Namana
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.4103/jomfp.jomfp_36_18
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.4103/jomfp.jomfp_36_18
Background: The Immunomorphological patterns of Lymph Nodes indirectly assess the host immune response facing a malignant tumor. These patterns also help us predict the susceptibility of the patient to Lymph Node Metastasis. Aims and Objectives: To evaluate the Immunomorphological patterns of Lymph Nodes in Oral Squamous Cell Carcinoma and to correlate them with the histopathological subtype of Oral Squamous Cell Carcinoma, TNM staging and the degree of tumor involvement within the Lymph Nodes. Methodology: A total of 40 subjects were taken for the study. Individuals who were clinically and histopathologically diagnosed as cases of Squamous Cell Carcinoma, who had undergone Radical or Elective Neck dissection were considered. The excised Lymph Nodes along with the primary tumor were collected stained with Hematoxylin and Eosin. The Lymph Nodes were assessed for Metastasis and Immunomorphological patterns. Statistical Correlation was done between the Immunomorphological pattern of Lymph Nodes and (a) Size of the tumor, (b) TNM stage of the tumor, (c) Histopathological Grade of the primary tumor, (d) Metastasis of the Lymph Node and (e) Grade of the Metastasis of Lymph Node. Statistical Correlation was done between the Metastasis of the Lymph Node and (a) Size of the tumor and (b) TNM stage of the tumor. Results and Conclusion: Statistically, a significant association was observed between TNM staging and Immunomorphological patterns of Lymph Node ( P < 0.01). The relationship between histopathological grade of primary tumor of Squamous Cell Carcinoma and the Immunomorphological patterns was statistically significant ( P < 0.01). Statistically, a significant association was observed between Sinus Histiocytosis pattern and decreased occurrence of nodal metastasis ( P < 0.01).
Related Topics
Concepts
Lymph
Medicine
Pathology
Metastasis
Neck dissection
Lymph node
Cervical lymph nodes
Stage (stratigraphy)
Primary tumor
H&E stain
Carcinoma
Cancer
Internal medicine
Immunohistochemistry
Biology
Paleontology
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.4103/jomfp.jomfp_36_18
- OA Status
- hybrid
- Cited By
- 5
- References
- 29
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3088219613
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3088219613Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.4103/jomfp.jomfp_36_18Digital Object Identifier
- Title
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Evaluation of immunomorphological patterns of cervical lymph nodes in oral squamous cell carcinomaWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-05-01Full publication date if available
- Authors
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Hyandavi Balla, Divya Uppala, Sumit Majumdar, Sreekanth Kotina, Sravya Kodati, Madhurya NamanaList of authors in order
- Landing page
-
https://doi.org/10.4103/jomfp.jomfp_36_18Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.4103/jomfp.jomfp_36_18Direct OA link when available
- Concepts
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Lymph, Medicine, Pathology, Metastasis, Neck dissection, Lymph node, Cervical lymph nodes, Stage (stratigraphy), Primary tumor, H&E stain, Carcinoma, Cancer, Internal medicine, Immunohistochemistry, Biology, PaleontologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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5Total citation count in OpenAlex
- Citations by year (recent)
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2024: 1, 2023: 1, 2022: 3Per-year citation counts (last 5 years)
- References (count)
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29Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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