Evaluation of rapid antigen test (ExacTest™ COVID-19 Antigen Rapid Test) results when omicron variant is common Article Swipe
Sedef Zeliha Öner
,
Büşra DÖNMEZ
,
İlknur Kaleli̇
,
Melek Demi̇r
,
Ergun Mete
,
Ahmet Çalışkan
,
Çağrı Ergin
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.31362/patd.1160801
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.31362/patd.1160801
Purpose: The present study aims to compare the results of the COVID-19 rapid antigen test (ExacTest™ COVID-19 Antigen Rapid Test) and real-time polymerase chain reaction (RT-PCR) test in samples of people suspected of coronavirus disease (COVID-19). Materials and Methods: Among the samples submitted between January 2022 and March 2022 with suspicion of COVID-19, 299 samples subject to simultaneous COVID-19 RADT (Rapid Antigen Detection Test) and RT-PCR were evaluated retrospectively. The Real-Time PCR test was studied with the DS CORONEX COVID-19 Multiplex Real time-qPCR Test Kit (DS Nano and Biotechnology Product Tracing and Tracking Co., Turkey) and the rapid antigen test was studied by the immunochromatographic method with ExacTest™ COVID-19 Antigen Rapid Test Cassette kit (General Diagnostica inc., California, USA). Ag-RDT test results were evaluated with the fluorescent immunoassay analyzer (FIATEST Analyzer, Hangzhou Alltest Biotech Co., Ltd. China). Results: RT-PCR test was positive in 53 (17.7%) samples. The RADT's sensitivity was found 88.7 (95% Cl 77.0-95.7), specificity 98.0 (95% Cl 95.3-99.3), positive predictive value 90.4 (95% Cl 79.7-95.8), negative predictive value 97.6 (95% Cl 95.0-98.8), and accuracy 96.3 (95% Cl 93.5-98.2). Sample sensitivities of patients under and over 18 years of age have been identified as 75 (95% Cl 19.4-99.4) and 89.8 (95% Cl 77.8-96.6), respectively. The sensitivity of patients with and without symptoms was 95.5 (95% Cl 77.2-99.9) and 83.9 (95% Cl 66.3-94.6), respectively. For samples with a cycle threshold (Ct) of
Related Topics
Concepts
Medicine
Coronavirus disease 2019 (COVID-19)
Antigen
Multiplex
Immunoassay
Real-time polymerase chain reaction
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Gold standard (test)
Polymerase chain reaction
Virology
Internal medicine
Immunology
Antibody
Chemistry
Biology
Disease
Gene
Infectious disease (medical specialty)
Bioinformatics
Biochemistry
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.31362/patd.1160801
- https://dergipark.org.tr/tr/download/article-file/2591485
- OA Status
- hybrid
- References
- 19
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4292485507
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4292485507Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.31362/patd.1160801Digital Object Identifier
- Title
-
Evaluation of rapid antigen test (ExacTest™ COVID-19 Antigen Rapid Test) results when omicron variant is commonWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-08-18Full publication date if available
- Authors
-
Sedef Zeliha Öner, Büşra DÖNMEZ, İlknur Kaleli̇, Melek Demi̇r, Ergun Mete, Ahmet Çalışkan, Çağrı ErginList of authors in order
- Landing page
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https://doi.org/10.31362/patd.1160801Publisher landing page
- PDF URL
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https://dergipark.org.tr/tr/download/article-file/2591485Direct link to full text PDF
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
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https://dergipark.org.tr/tr/download/article-file/2591485Direct OA link when available
- Concepts
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Medicine, Coronavirus disease 2019 (COVID-19), Antigen, Multiplex, Immunoassay, Real-time polymerase chain reaction, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Gold standard (test), Polymerase chain reaction, Virology, Internal medicine, Immunology, Antibody, Chemistry, Biology, Disease, Gene, Infectious disease (medical specialty), Bioinformatics, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
-
19Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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