Evaluation of the Effect of Garlic Tablet as a Complementary Treatment for Patients with Diabetic Retinopathy Article Swipe
Mehrdad Afarid
,
Elham Sadeghi
,
Mohammadkarim Johari
,
Ehsan Namvar
,
Fatemeh Sanie‐Jahromi
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1155/2022/6620661
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1155/2022/6620661
Purpose. The aim of this study was to investigate the effectiveness of garlic (Allium sativum L.) tablets as a complimentary herbal medication in diabetic macular edema. Methods. A total of 91 diabetic participants (117 eyes) with central involved macular edema underwent a double-blind randomized trial. The patients used garlic tablets (500 mg) (2 tab/day) or placebo for 4 weeks and subsequently were examined by an expert ophthalmologist. Clinical manifestations including the best-corrected visual acuity (BCVA, logMAR), central macular thickness (CMT, μm), and intraocular pressure (IOP) were measured as the main outcomes. Results. BCVA was significantly improved by a 0.18 decrease in mean logMAR value in the garlic-treated patients in comparison with 0.06 in the control ones ( P value = 0.027 ). CMT was decreased in both groups by a 102.99 μm decrease in the garlic group compared to 52.67 μm in the placebo group, albeit in a nonsignificant manner ( P value: 0.094). IOP was decreased in the garlic group by 1.03 mmHg ( P value: 0.024) and increased by 0.3 mmHg ( P value: 0.468) in the placebo group. Conclusion. Our trial suggests that garlic supplements can improve visual acuity, decrease the CMT and lower the IOP, and can be considered as an adjuvant treatment in patients with diabetic macular edema. Garlic was satisfactorily tolerated in diabetic patients, and no significant adverse effect interrupting the safety profile was observed.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1155/2022/6620661
- https://downloads.hindawi.com/journals/jdr/2022/6620661.pdf
- OA Status
- gold
- Cited By
- 19
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4285391077
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4285391077Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1155/2022/6620661Digital Object Identifier
- Title
-
Evaluation of the Effect of Garlic Tablet as a Complementary Treatment for Patients with Diabetic RetinopathyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-07-14Full publication date if available
- Authors
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Mehrdad Afarid, Elham Sadeghi, Mohammadkarim Johari, Ehsan Namvar, Fatemeh Sanie‐JahromiList of authors in order
- Landing page
-
https://doi.org/10.1155/2022/6620661Publisher landing page
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https://downloads.hindawi.com/journals/jdr/2022/6620661.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://downloads.hindawi.com/journals/jdr/2022/6620661.pdfDirect OA link when available
- Concepts
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Diabetic retinopathy, Medicine, Retinopathy, Traditional medicine, Ophthalmology, Diabetes mellitus, EndocrinologyTop concepts (fields/topics) attached by OpenAlex
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19Total citation count in OpenAlex
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2025: 8, 2024: 7, 2023: 3, 2022: 1Per-year citation counts (last 5 years)
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46Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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