Evaluation of the Effect of Thickeners in Enteral Formulas on the Gastric Emptying Rate of Proteins and Carbohydrates Using a Semi-Dynamic Gastric Model Article Swipe
Motoki Tsukiashi
,
Takahiro Koyama
,
Hiroshi Iwamoto
,
Hirofumi Sonoki
,
Kazuhiro Miyaji
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/nu16132115
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/nu16132115
The emptying rate of specific nutrients in enteral formulas is poorly understood, despite the importance of controlling the emptying rate in tube-fed patients. Because of their viscosity, thickened formulas are widely used to avoid gastric reflux and reduce the burden on caregivers. This study examined how thickeners in enteral formulas affected the gastric emptying rates of proteins and carbohydrates. A semi-dynamic gastric model was used to prepare and digest test enteral formulas that contained either no thickeners or agar (0.2%). The amounts of protein and carbohydrates in each emptied aliquot were determined, and the emptying rate was calculated. We found that agar accelerated protein emptying, and an exploratory experiment with agar (0.5%) suggested the possibility of concentration dependence. Additionally, experiments using gellan gum (0.08%), guar gum (0.2%), or carrageenan (0.08%, 0.2%) suggested that protein emptying could vary depending on the thickener type and that carrageenan might slow it. These results could help with the appropriate selection of thickeners added to liquid foods based on the patient’s metabolic profile to manage nutrition, not only for tube-fed patients but also for those with oropharyngeal dysphagia or diabetes.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/nu16132115
- OA Status
- gold
- Cited By
- 2
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4400238455
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4400238455Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/nu16132115Digital Object Identifier
- Title
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Evaluation of the Effect of Thickeners in Enteral Formulas on the Gastric Emptying Rate of Proteins and Carbohydrates Using a Semi-Dynamic Gastric ModelWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-07-02Full publication date if available
- Authors
-
Motoki Tsukiashi, Takahiro Koyama, Hiroshi Iwamoto, Hirofumi Sonoki, Kazuhiro MiyajiList of authors in order
- Landing page
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https://doi.org/10.3390/nu16132115Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.3390/nu16132115Direct OA link when available
- Concepts
-
Gastric emptying, Gastroenterology, Enteral administration, Parenteral nutrition, Medicine, Internal medicine, Stomach, Chemistry, Food scienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
2Total citation count in OpenAlex
- Citations by year (recent)
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2025: 2Per-year citation counts (last 5 years)
- References (count)
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46Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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