Evaluation safety and efficacy of immune checkpoint blockers (ICB ) and radiotherapy combination versus ICB in non‐small cell lung cancer patients with recurrence or metastasis: A systematic review and meta‐analysis
Article Swipe
Yichun Zeng
,
Liying Zhang
,
Yichen Liang
,
Xian Zhang
,
Lei Li
,
Maoqi Wang
,
Jingliang Guo
,
Qiuxian Li
,
Cao Jin
,
Juan J. Gu
,
Buhai Wang
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1002/cam4.5958
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1002/cam4.5958
Background Currently, immune checkpoint blockers (ICB) and radiotherapy (RT) combination therapy is broadly applied in non‐small cell lung cancer (NSCLC) patients. However, meta‐analysis about safety and efficacy of RT + ICB versus ICB has not yet been reported. To evaluate safety and efficacy of the combination therapy of ICB and RT in patients with recurrent or metastatic NSCLC and explore factors related to higher response rates, longer lifetime, and lower toxicity, meta‐analysis of previous clinical data will be presented in this article. Methods A literature search on patients with recurrent or metastatic NSCLC treated with RT + ICB versus ICB was performed using the Cochrane Library, Embase and PubMed up to December 10, 2022. Suitable quality assessment checklists were selected corresponding to various types of research studies. Comparative and single‐arm studies were analyzed using Stata 14.0. Results 10 comparative studies and 15 arms of combination therapy were included for this meta‐analysis. RT significantly improved objective response rate (ORR), disease control rate (DCR), and overall survival (OS) and progression‐free survival (PFS) of ICB (I‐square value ( I 2 ) = 0.00%, odds ratio (OR) 1.28, 95% confidence interval (CI) 1.09–1.49, I 2 = 0.00%, OR 1.12, 95% CI 1.00–1.25, I 2 = 42.1%, OR 0.81, 95% CI 0.72–0.92, I 2 = 34.5%, OR 0.80, and 95% CI 0.71–0.89, respectively). Toxicity between combination therapy and ICB monotherapy did not significantly differ in any grade or in ≥3 grade of tr‐AEs ( I 2 = 0.00%, OR 1.05, 95% CI 0.91–1.22, I 2 = 0.00%, OR 1.46, 95% CI 0.90–2.37, respectively). Subgroup analyses based on single‐arm studies showed that applications of SRS/SBRT, PD‐1 inhibitor, and administration of ICB after RT were conducive to a better DCR, longer OS and mild adverse events (heterogeneity between groups (HBG) all p < 0.05). Conclusion RT can significantly improve ORR, DCR, OS, and PFS of ICB in patients with recurrent or metastatic NSCLC without increasing toxicity. PD‐1 inhibitor following SRS/SBRT could be the best option to maximally benefit the patients.
Related Topics
Concepts
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1002/cam4.5958
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.5958
- OA Status
- gold
- Cited By
- 4
- References
- 45
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4380871513
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4380871513Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1002/cam4.5958Digital Object Identifier
- Title
-
Evaluation safety and efficacy of immune checkpoint blockers (
ICB ) and radiotherapy combination versusICB in non‐small cell lung cancer patients with recurrence or metastasis: A systematic review and meta‐analysisWork title - Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-06-16Full publication date if available
- Authors
-
Yichun Zeng, Liying Zhang, Yichen Liang, Xian Zhang, Lei Li, Maoqi Wang, Jingliang Guo, Qiuxian Li, Cao Jin, Juan J. Gu, Buhai WangList of authors in order
- Landing page
-
https://doi.org/10.1002/cam4.5958Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.5958Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.5958Direct OA link when available
- Concepts
-
Medicine, Internal medicine, Oncology, Lung cancer, Radiation therapy, Confidence interval, Meta-analysis, Combination therapy, Odds ratioTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
4Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 2, 2023: 1Per-year citation counts (last 5 years)
- References (count)
-
45Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4380871513 |
|---|---|
| doi | https://doi.org/10.1002/cam4.5958 |
| ids.doi | https://doi.org/10.1002/cam4.5958 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/37323098 |
| ids.openalex | https://openalex.org/W4380871513 |
| fwci | 0.95038811 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000188 |
| mesh[1].descriptor_ui | D002289 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | drug therapy |
| mesh[1].descriptor_name | Carcinoma, Non-Small-Cell Lung |
| mesh[2].qualifier_ui | Q000532 |
| mesh[2].descriptor_ui | D002289 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | radiotherapy |
| mesh[2].descriptor_name | Carcinoma, Non-Small-Cell Lung |
| mesh[3].qualifier_ui | Q000009 |
| mesh[3].descriptor_ui | D000082082 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | adverse effects |
| mesh[3].descriptor_name | Immune Checkpoint Inhibitors |
| mesh[4].qualifier_ui | Q000188 |
| mesh[4].descriptor_ui | D008175 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | drug therapy |
| mesh[4].descriptor_name | Lung Neoplasms |
| mesh[5].qualifier_ui | Q000532 |
| mesh[5].descriptor_ui | D008175 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | radiotherapy |
| mesh[5].descriptor_name | Lung Neoplasms |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D003131 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Combined Modality Therapy |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D006801 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Humans |
| mesh[8].qualifier_ui | Q000188 |
| mesh[8].descriptor_ui | D002289 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | drug therapy |
| mesh[8].descriptor_name | Carcinoma, Non-Small-Cell Lung |
| mesh[9].qualifier_ui | Q000532 |
| mesh[9].descriptor_ui | D002289 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | radiotherapy |
| mesh[9].descriptor_name | Carcinoma, Non-Small-Cell Lung |
| mesh[10].qualifier_ui | Q000009 |
| mesh[10].descriptor_ui | D000082082 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | adverse effects |
| mesh[10].descriptor_name | Immune Checkpoint Inhibitors |
| mesh[11].qualifier_ui | Q000188 |
| mesh[11].descriptor_ui | D008175 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | drug therapy |
| mesh[11].descriptor_name | Lung Neoplasms |
| mesh[12].qualifier_ui | Q000532 |
| mesh[12].descriptor_ui | D008175 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | radiotherapy |
| mesh[12].descriptor_name | Lung Neoplasms |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D003131 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Combined Modality Therapy |
| type | review |
| title | Evaluation safety and efficacy of immune checkpoint blockers ( |
| biblio.issue | 13 |
| biblio.volume | 12 |
| biblio.last_page | 13941 |
| biblio.first_page | 13928 |
| topics[0].id | https://openalex.org/T10158 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2730 |
| topics[0].subfield.display_name | Oncology |
| topics[0].display_name | Cancer Immunotherapy and Biomarkers |
| topics[1].id | https://openalex.org/T12334 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9988999962806702 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2730 |
| topics[1].subfield.display_name | Oncology |
| topics[1].display_name | Lung Cancer Research Studies |
| topics[2].id | https://openalex.org/T10417 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9986000061035156 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2740 |
| topics[2].subfield.display_name | Pulmonary and Respiratory Medicine |
| topics[2].display_name | Lung Cancer Treatments and Mutations |
| is_xpac | False |
| apc_list.value | 2300 |
| apc_list.currency | EUR |
| apc_list.value_usd | 3025 |
| apc_paid.value | 2300 |
| apc_paid.currency | EUR |
| apc_paid.value_usd | 3025 |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.7901595830917358 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C126322002 |
| concepts[1].level | 1 |
| concepts[1].score | 0.6941876411437988 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[1].display_name | Internal medicine |
| concepts[2].id | https://openalex.org/C143998085 |
| concepts[2].level | 1 |
| concepts[2].score | 0.649877667427063 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q162555 |
| concepts[2].display_name | Oncology |
| concepts[3].id | https://openalex.org/C2776256026 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6070841550827026 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q47912 |
| concepts[3].display_name | Lung cancer |
| concepts[4].id | https://openalex.org/C509974204 |
| concepts[4].level | 2 |
| concepts[4].score | 0.553663432598114 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q180507 |
| concepts[4].display_name | Radiation therapy |
| concepts[5].id | https://openalex.org/C44249647 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5520574450492859 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q208498 |
| concepts[5].display_name | Confidence interval |
| concepts[6].id | https://openalex.org/C95190672 |
| concepts[6].level | 2 |
| concepts[6].score | 0.5280573964118958 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q815382 |
| concepts[6].display_name | Meta-analysis |
| concepts[7].id | https://openalex.org/C2776999253 |
| concepts[7].level | 2 |
| concepts[7].score | 0.494373083114624 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1304270 |
| concepts[7].display_name | Combination therapy |
| concepts[8].id | https://openalex.org/C156957248 |
| concepts[8].level | 2 |
| concepts[8].score | 0.4865197539329529 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q1862216 |
| concepts[8].display_name | Odds ratio |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.7901595830917358 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/internal-medicine |
| keywords[1].score | 0.6941876411437988 |
| keywords[1].display_name | Internal medicine |
| keywords[2].id | https://openalex.org/keywords/oncology |
| keywords[2].score | 0.649877667427063 |
| keywords[2].display_name | Oncology |
| keywords[3].id | https://openalex.org/keywords/lung-cancer |
| keywords[3].score | 0.6070841550827026 |
| keywords[3].display_name | Lung cancer |
| keywords[4].id | https://openalex.org/keywords/radiation-therapy |
| keywords[4].score | 0.553663432598114 |
| keywords[4].display_name | Radiation therapy |
| keywords[5].id | https://openalex.org/keywords/confidence-interval |
| keywords[5].score | 0.5520574450492859 |
| keywords[5].display_name | Confidence interval |
| keywords[6].id | https://openalex.org/keywords/meta-analysis |
| keywords[6].score | 0.5280573964118958 |
| keywords[6].display_name | Meta-analysis |
| keywords[7].id | https://openalex.org/keywords/combination-therapy |
| keywords[7].score | 0.494373083114624 |
| keywords[7].display_name | Combination therapy |
| keywords[8].id | https://openalex.org/keywords/odds-ratio |
| keywords[8].score | 0.4865197539329529 |
| keywords[8].display_name | Odds ratio |
| language | en |
| locations[0].id | doi:10.1002/cam4.5958 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2754843627 |
| locations[0].source.issn | 2045-7634 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2045-7634 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Cancer Medicine |
| locations[0].source.host_organization | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_name | Wiley |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320595 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.5958 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Cancer Medicine |
| locations[0].landing_page_url | https://doi.org/10.1002/cam4.5958 |
| locations[1].id | pmid:37323098 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Cancer medicine |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/37323098 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:10358264 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | cc-by |
| locations[2].pdf_url | https://pmc.ncbi.nlm.nih.gov/articles/PMC10358264/pdf/CAM4-12-13928.pdf |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/cc-by |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Cancer Med |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/10358264 |
| locations[3].id | pmh:oai:doaj.org/article:302bb34d569445298a091f62ee3d33bd |
| locations[3].is_oa | False |
| locations[3].source.id | https://openalex.org/S4306401280 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[3].source.host_organization | |
| locations[3].source.host_organization_name | |
| locations[3].source.host_organization_lineage | |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | article |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Cancer Medicine, Vol 12, Iss 13, Pp 13928-13941 (2023) |
| locations[3].landing_page_url | https://doaj.org/article/302bb34d569445298a091f62ee3d33bd |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5080188070 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Yichun Zeng |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I78978612 |
| authorships[0].affiliations[0].raw_affiliation_string | Medical College of Yangzhou University, Yangzhou, China |
| authorships[0].institutions[0].id | https://openalex.org/I78978612 |
| authorships[0].institutions[0].ror | https://ror.org/03tqb8s11 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I78978612 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Yangzhou University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Yichun Zeng |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Medical College of Yangzhou University, Yangzhou, China |
| authorships[1].author.id | https://openalex.org/A5100357105 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-4517-0751 |
| authorships[1].author.display_name | Liying Zhang |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210137355 |
| authorships[1].affiliations[0].raw_affiliation_string | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[1].institutions[0].id | https://openalex.org/I4210137355 |
| authorships[1].institutions[0].ror | https://ror.org/04gz17b59 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210137355 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Northern Jiangsu People's Hospital |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Liying Zhang |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[2].author.id | https://openalex.org/A5101050005 |
| authorships[2].author.orcid | https://orcid.org/0009-0007-9382-7267 |
| authorships[2].author.display_name | Yichen Liang |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210137355 |
| authorships[2].affiliations[0].raw_affiliation_string | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[2].institutions[0].id | https://openalex.org/I4210137355 |
| authorships[2].institutions[0].ror | https://ror.org/04gz17b59 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210137355 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Northern Jiangsu People's Hospital |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Yichen Liang |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[3].author.id | https://openalex.org/A5100438832 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-9674-7886 |
| authorships[3].author.display_name | Xian Zhang |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210137355 |
| authorships[3].affiliations[0].raw_affiliation_string | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[3].institutions[0].id | https://openalex.org/I4210137355 |
| authorships[3].institutions[0].ror | https://ror.org/04gz17b59 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210137355 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Northern Jiangsu People's Hospital |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Xian Zhang |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[4].author.id | https://openalex.org/A5100341824 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-7001-7471 |
| authorships[4].author.display_name | Lei Li |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I191996457 |
| authorships[4].affiliations[0].raw_affiliation_string | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[4].institutions[0].id | https://openalex.org/I191996457 |
| authorships[4].institutions[0].ror | https://ror.org/04c8eg608 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I191996457 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Dalian Medical University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Lei Li |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[5].author.id | https://openalex.org/A5074487817 |
| authorships[5].author.orcid | https://orcid.org/0009-0003-0745-3715 |
| authorships[5].author.display_name | Maoqi Wang |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I191996457 |
| authorships[5].affiliations[0].raw_affiliation_string | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[5].institutions[0].id | https://openalex.org/I191996457 |
| authorships[5].institutions[0].ror | https://ror.org/04c8eg608 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I191996457 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | Dalian Medical University |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Maoqi Wang |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[6].author.id | https://openalex.org/A5102509664 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Jingliang Guo |
| authorships[6].countries | CN |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I191996457 |
| authorships[6].affiliations[0].raw_affiliation_string | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[6].institutions[0].id | https://openalex.org/I191996457 |
| authorships[6].institutions[0].ror | https://ror.org/04c8eg608 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I191996457 |
| authorships[6].institutions[0].country_code | CN |
| authorships[6].institutions[0].display_name | Dalian Medical University |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Jingliang Guo |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[7].author.id | https://openalex.org/A5023867457 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-7246-5910 |
| authorships[7].author.display_name | Qiuxian Li |
| authorships[7].countries | CN |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I191996457 |
| authorships[7].affiliations[0].raw_affiliation_string | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[7].institutions[0].id | https://openalex.org/I191996457 |
| authorships[7].institutions[0].ror | https://ror.org/04c8eg608 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I191996457 |
| authorships[7].institutions[0].country_code | CN |
| authorships[7].institutions[0].display_name | Dalian Medical University |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Qiuxian Li |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[8].author.id | https://openalex.org/A5057967569 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-5433-2911 |
| authorships[8].author.display_name | Cao Jin |
| authorships[8].countries | CN |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I78978612 |
| authorships[8].affiliations[0].raw_affiliation_string | Medical College of Yangzhou University, Yangzhou, China |
| authorships[8].institutions[0].id | https://openalex.org/I78978612 |
| authorships[8].institutions[0].ror | https://ror.org/03tqb8s11 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I78978612 |
| authorships[8].institutions[0].country_code | CN |
| authorships[8].institutions[0].display_name | Yangzhou University |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Jin Cao |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Medical College of Yangzhou University, Yangzhou, China |
| authorships[9].author.id | https://openalex.org/A5042570714 |
| authorships[9].author.orcid | https://orcid.org/0009-0003-4640-2152 |
| authorships[9].author.display_name | Juan J. Gu |
| authorships[9].countries | CN |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I4210137355 |
| authorships[9].affiliations[0].raw_affiliation_string | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[9].institutions[0].id | https://openalex.org/I4210137355 |
| authorships[9].institutions[0].ror | https://ror.org/04gz17b59 |
| authorships[9].institutions[0].type | healthcare |
| authorships[9].institutions[0].lineage | https://openalex.org/I4210137355 |
| authorships[9].institutions[0].country_code | CN |
| authorships[9].institutions[0].display_name | Northern Jiangsu People's Hospital |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Juan J. Gu |
| authorships[9].is_corresponding | True |
| authorships[9].raw_affiliation_strings | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[10].author.id | https://openalex.org/A5025681830 |
| authorships[10].author.orcid | https://orcid.org/0000-0001-6391-4502 |
| authorships[10].author.display_name | Buhai Wang |
| authorships[10].countries | CN |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I78978612 |
| authorships[10].affiliations[0].raw_affiliation_string | Medical College of Yangzhou University, Yangzhou, China |
| authorships[10].affiliations[1].institution_ids | https://openalex.org/I191996457 |
| authorships[10].affiliations[1].raw_affiliation_string | Medical College of Dalian Medical University, Yangzhou, China |
| authorships[10].affiliations[2].institution_ids | https://openalex.org/I4210137355 |
| authorships[10].affiliations[2].raw_affiliation_string | Northern Jiangsu People's Hospital, Yangzhou, China |
| authorships[10].institutions[0].id | https://openalex.org/I191996457 |
| authorships[10].institutions[0].ror | https://ror.org/04c8eg608 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I191996457 |
| authorships[10].institutions[0].country_code | CN |
| authorships[10].institutions[0].display_name | Dalian Medical University |
| authorships[10].institutions[1].id | https://openalex.org/I4210137355 |
| authorships[10].institutions[1].ror | https://ror.org/04gz17b59 |
| authorships[10].institutions[1].type | healthcare |
| authorships[10].institutions[1].lineage | https://openalex.org/I4210137355 |
| authorships[10].institutions[1].country_code | CN |
| authorships[10].institutions[1].display_name | Northern Jiangsu People's Hospital |
| authorships[10].institutions[2].id | https://openalex.org/I78978612 |
| authorships[10].institutions[2].ror | https://ror.org/03tqb8s11 |
| authorships[10].institutions[2].type | education |
| authorships[10].institutions[2].lineage | https://openalex.org/I78978612 |
| authorships[10].institutions[2].country_code | CN |
| authorships[10].institutions[2].display_name | Yangzhou University |
| authorships[10].author_position | last |
| authorships[10].raw_author_name | Buhai Wang |
| authorships[10].is_corresponding | True |
| authorships[10].raw_affiliation_strings | Medical College of Dalian Medical University, Yangzhou, China, Medical College of Yangzhou University, Yangzhou, China, Northern Jiangsu People's Hospital, Yangzhou, China |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.5958 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2023-06-17T00:00:00 |
| display_name | Evaluation safety and efficacy of immune checkpoint blockers ( |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10158 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2730 |
| primary_topic.subfield.display_name | Oncology |
| primary_topic.display_name | Cancer Immunotherapy and Biomarkers |
| related_works | https://openalex.org/W2611523470, https://openalex.org/W3210678099, https://openalex.org/W2355955825, https://openalex.org/W4246615163, https://openalex.org/W4360943417, https://openalex.org/W2981696006, https://openalex.org/W4386361997, https://openalex.org/W2417314287, https://openalex.org/W2064573700, https://openalex.org/W2286371484 |
| cited_by_count | 4 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 2 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 1 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1002/cam4.5958 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2754843627 |
| best_oa_location.source.issn | 2045-7634 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2045-7634 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Cancer Medicine |
| best_oa_location.source.host_organization | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_name | Wiley |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.5958 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Cancer Medicine |
| best_oa_location.landing_page_url | https://doi.org/10.1002/cam4.5958 |
| primary_location.id | doi:10.1002/cam4.5958 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2754843627 |
| primary_location.source.issn | 2045-7634 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2045-7634 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Cancer Medicine |
| primary_location.source.host_organization | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_name | Wiley |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.5958 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Cancer Medicine |
| primary_location.landing_page_url | https://doi.org/10.1002/cam4.5958 |
| publication_date | 2023-06-16 |
| publication_year | 2023 |
| referenced_works | https://openalex.org/W3119005666, https://openalex.org/W2753065806, https://openalex.org/W3108819942, https://openalex.org/W2902185751, https://openalex.org/W2618641368, https://openalex.org/W4206362366, https://openalex.org/W2956407134, https://openalex.org/W4212871392, https://openalex.org/W3143011862, https://openalex.org/W2792319162, https://openalex.org/W2897669799, https://openalex.org/W4206520893, https://openalex.org/W3183933090, https://openalex.org/W3004373164, https://openalex.org/W2978795816, https://openalex.org/W2017044005, https://openalex.org/W2402421755, https://openalex.org/W2088095316, https://openalex.org/W2789601009, https://openalex.org/W4214616651, https://openalex.org/W3092354477, https://openalex.org/W2983088525, https://openalex.org/W3034353821, https://openalex.org/W3092159910, https://openalex.org/W4297184099, https://openalex.org/W4283660756, https://openalex.org/W2972727248, https://openalex.org/W3197047635, https://openalex.org/W3100127092, https://openalex.org/W4308183711, https://openalex.org/W2785312166, https://openalex.org/W3124921786, https://openalex.org/W2900705038, https://openalex.org/W4295561194, https://openalex.org/W2989894061, https://openalex.org/W2923936350, https://openalex.org/W2936890487, https://openalex.org/W2032166347, https://openalex.org/W2423232887, https://openalex.org/W3123073834, https://openalex.org/W3162040459, https://openalex.org/W3146253175, https://openalex.org/W4206435283, https://openalex.org/W4226445717, https://openalex.org/W4380871513 |
| referenced_works_count | 45 |
| abstract_inverted_index.( | 175, 239 |
| abstract_inverted_index.) | 178 |
| abstract_inverted_index.+ | 30, 97 |
| abstract_inverted_index.2 | 177, 191, 200, 209, 241, 250 |
| abstract_inverted_index.= | 179, 192, 201, 210, 242, 251 |
| abstract_inverted_index.A | 84 |
| abstract_inverted_index.I | 176, 190, 199, 208, 240, 249 |
| abstract_inverted_index.a | 281 |
| abstract_inverted_index.p | 295 |
| abstract_inverted_index.10 | 138 |
| abstract_inverted_index.15 | 142 |
| abstract_inverted_index.CI | 197, 206, 216, 247, 256 |
| abstract_inverted_index.OR | 194, 203, 212, 244, 253 |
| abstract_inverted_index.OS | 285 |
| abstract_inverted_index.RT | 29, 51, 96, 152, 277, 299 |
| abstract_inverted_index.To | 39 |
| abstract_inverted_index.be | 78, 325 |
| abstract_inverted_index.in | 15, 52, 80, 230, 234, 310 |
| abstract_inverted_index.is | 12 |
| abstract_inverted_index.of | 28, 44, 48, 73, 125, 144, 171, 237, 268, 274, 308 |
| abstract_inverted_index.on | 87, 262 |
| abstract_inverted_index.or | 56, 91, 233, 314 |
| abstract_inverted_index.to | 63, 111, 122, 280, 329 |
| abstract_inverted_index.up | 110 |
| abstract_inverted_index.10, | 113 |
| abstract_inverted_index.95% | 185, 196, 205, 215, 246, 255 |
| abstract_inverted_index.ICB | 31, 33, 49, 98, 100, 172, 224, 275, 309 |
| abstract_inverted_index.OS, | 305 |
| abstract_inverted_index.PFS | 307 |
| abstract_inverted_index.all | 294 |
| abstract_inverted_index.and | 7, 26, 42, 50, 59, 69, 108, 129, 141, 163, 167, 214, 223, 272, 286, 306 |
| abstract_inverted_index.any | 231 |
| abstract_inverted_index.can | 300 |
| abstract_inverted_index.did | 226 |
| abstract_inverted_index.for | 149 |
| abstract_inverted_index.has | 34 |
| abstract_inverted_index.not | 35, 227 |
| abstract_inverted_index.the | 45, 104, 326, 332 |
| abstract_inverted_index.was | 101 |
| abstract_inverted_index.yet | 36 |
| abstract_inverted_index.< | 296 |
| abstract_inverted_index.(CI) | 188 |
| abstract_inverted_index.(OR) | 183 |
| abstract_inverted_index.(OS) | 166 |
| abstract_inverted_index.(RT) | 9 |
| abstract_inverted_index.DCR, | 283, 304 |
| abstract_inverted_index.ORR, | 303 |
| abstract_inverted_index.arms | 143 |
| abstract_inverted_index.been | 37 |
| abstract_inverted_index.best | 327 |
| abstract_inverted_index.cell | 17 |
| abstract_inverted_index.data | 76 |
| abstract_inverted_index.lung | 18 |
| abstract_inverted_index.mild | 287 |
| abstract_inverted_index.odds | 181 |
| abstract_inverted_index.rate | 157, 161 |
| abstract_inverted_index.that | 266 |
| abstract_inverted_index.this | 81, 150 |
| abstract_inverted_index.were | 119, 132, 147, 278 |
| abstract_inverted_index.will | 77 |
| abstract_inverted_index.with | 54, 89, 95, 312 |
| abstract_inverted_index.≥3 | 235 |
| abstract_inverted_index.(HBG) | 293 |
| abstract_inverted_index.(ICB) | 6 |
| abstract_inverted_index.(PFS) | 170 |
| abstract_inverted_index.0.80, | 213 |
| abstract_inverted_index.0.81, | 204 |
| abstract_inverted_index.1.05, | 245 |
| abstract_inverted_index.1.12, | 195 |
| abstract_inverted_index.1.28, | 184 |
| abstract_inverted_index.1.46, | 254 |
| abstract_inverted_index.14.0. | 136 |
| abstract_inverted_index.2022. | 114 |
| abstract_inverted_index.NSCLC | 58, 93, 316 |
| abstract_inverted_index.Stata | 135 |
| abstract_inverted_index.about | 24 |
| abstract_inverted_index.after | 276 |
| abstract_inverted_index.based | 261 |
| abstract_inverted_index.could | 324 |
| abstract_inverted_index.grade | 232, 236 |
| abstract_inverted_index.lower | 70 |
| abstract_inverted_index.ratio | 182 |
| abstract_inverted_index.types | 124 |
| abstract_inverted_index.using | 103, 134 |
| abstract_inverted_index.value | 174 |
| abstract_inverted_index.(DCR), | 162 |
| abstract_inverted_index.(ORR), | 158 |
| abstract_inverted_index.0.00%, | 180, 193, 243, 252 |
| abstract_inverted_index.0.05). | 297 |
| abstract_inverted_index.34.5%, | 211 |
| abstract_inverted_index.42.1%, | 202 |
| abstract_inverted_index.Embase | 107 |
| abstract_inverted_index.PD‐1 | 270, 320 |
| abstract_inverted_index.PubMed | 109 |
| abstract_inverted_index.better | 282 |
| abstract_inverted_index.cancer | 19 |
| abstract_inverted_index.differ | 229 |
| abstract_inverted_index.events | 289 |
| abstract_inverted_index.groups | 292 |
| abstract_inverted_index.higher | 64 |
| abstract_inverted_index.immune | 3 |
| abstract_inverted_index.longer | 67, 284 |
| abstract_inverted_index.option | 328 |
| abstract_inverted_index.rates, | 66 |
| abstract_inverted_index.safety | 25, 41 |
| abstract_inverted_index.search | 86 |
| abstract_inverted_index.showed | 265 |
| abstract_inverted_index.versus | 32, 99 |
| abstract_inverted_index.(NSCLC) | 20 |
| abstract_inverted_index.Methods | 83 |
| abstract_inverted_index.Results | 137 |
| abstract_inverted_index.adverse | 288 |
| abstract_inverted_index.applied | 14 |
| abstract_inverted_index.benefit | 331 |
| abstract_inverted_index.between | 220, 291 |
| abstract_inverted_index.broadly | 13 |
| abstract_inverted_index.control | 160 |
| abstract_inverted_index.disease | 159 |
| abstract_inverted_index.explore | 60 |
| abstract_inverted_index.factors | 61 |
| abstract_inverted_index.improve | 302 |
| abstract_inverted_index.overall | 164 |
| abstract_inverted_index.quality | 116 |
| abstract_inverted_index.related | 62 |
| abstract_inverted_index.studies | 131, 140, 264 |
| abstract_inverted_index.therapy | 11, 47, 146, 222 |
| abstract_inverted_index.treated | 94 |
| abstract_inverted_index.various | 123 |
| abstract_inverted_index.without | 317 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Cochrane | 105 |
| abstract_inverted_index.December | 112 |
| abstract_inverted_index.However, | 22 |
| abstract_inverted_index.Library, | 106 |
| abstract_inverted_index.SRS/SBRT | 323 |
| abstract_inverted_index.Subgroup | 259 |
| abstract_inverted_index.Suitable | 115 |
| abstract_inverted_index.Toxicity | 219 |
| abstract_inverted_index.analyses | 260 |
| abstract_inverted_index.analyzed | 133 |
| abstract_inverted_index.article. | 82 |
| abstract_inverted_index.blockers | 5 |
| abstract_inverted_index.clinical | 75 |
| abstract_inverted_index.efficacy | 27, 43 |
| abstract_inverted_index.evaluate | 40 |
| abstract_inverted_index.improved | 154 |
| abstract_inverted_index.included | 148 |
| abstract_inverted_index.interval | 187 |
| abstract_inverted_index.patients | 53, 88, 311 |
| abstract_inverted_index.previous | 74 |
| abstract_inverted_index.research | 126 |
| abstract_inverted_index.response | 65, 156 |
| abstract_inverted_index.selected | 120 |
| abstract_inverted_index.studies. | 127 |
| abstract_inverted_index.survival | 165, 169 |
| abstract_inverted_index.tr‐AEs | 238 |
| abstract_inverted_index.SRS/SBRT, | 269 |
| abstract_inverted_index.conducive | 279 |
| abstract_inverted_index.following | 322 |
| abstract_inverted_index.inhibitor | 321 |
| abstract_inverted_index.lifetime, | 68 |
| abstract_inverted_index.maximally | 330 |
| abstract_inverted_index.objective | 155 |
| abstract_inverted_index.patients. | 21, 333 |
| abstract_inverted_index.performed | 102 |
| abstract_inverted_index.presented | 79 |
| abstract_inverted_index.recurrent | 55, 90, 313 |
| abstract_inverted_index.reported. | 38 |
| abstract_inverted_index.toxicity, | 71 |
| abstract_inverted_index.toxicity. | 319 |
| abstract_inverted_index.Background | 1 |
| abstract_inverted_index.Conclusion | 298 |
| abstract_inverted_index.Currently, | 2 |
| abstract_inverted_index.assessment | 117 |
| abstract_inverted_index.checklists | 118 |
| abstract_inverted_index.checkpoint | 4 |
| abstract_inverted_index.confidence | 186 |
| abstract_inverted_index.increasing | 318 |
| abstract_inverted_index.inhibitor, | 271 |
| abstract_inverted_index.literature | 85 |
| abstract_inverted_index.metastatic | 57, 92, 315 |
| abstract_inverted_index.(I‐square | 173 |
| abstract_inverted_index.Comparative | 128 |
| abstract_inverted_index.combination | 10, 46, 145, 221 |
| abstract_inverted_index.comparative | 139 |
| abstract_inverted_index.monotherapy | 225 |
| abstract_inverted_index.non‐small | 16 |
| abstract_inverted_index.0.71–0.89, | 217 |
| abstract_inverted_index.0.72–0.92, | 207 |
| abstract_inverted_index.0.90–2.37, | 257 |
| abstract_inverted_index.0.91–1.22, | 248 |
| abstract_inverted_index.1.00–1.25, | 198 |
| abstract_inverted_index.1.09–1.49, | 189 |
| abstract_inverted_index.applications | 267 |
| abstract_inverted_index.radiotherapy | 8 |
| abstract_inverted_index.single‐arm | 130, 263 |
| abstract_inverted_index.corresponding | 121 |
| abstract_inverted_index.significantly | 153, 228, 301 |
| abstract_inverted_index.(heterogeneity | 290 |
| abstract_inverted_index.administration | 273 |
| abstract_inverted_index.respectively). | 218, 258 |
| abstract_inverted_index.meta‐analysis | 23, 72 |
| abstract_inverted_index.meta‐analysis. | 151 |
| abstract_inverted_index.progression‐free | 168 |
| cited_by_percentile_year.max | 96 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5025681830, https://openalex.org/A5042570714 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 11 |
| corresponding_institution_ids | https://openalex.org/I191996457, https://openalex.org/I4210137355, https://openalex.org/I78978612 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7200000286102295 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.81408474 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |