Evolutionary and structural basis of SLAMF1 utilization in morbilliviruses—Implications for host range and cross-species transmission Article Swipe
Ayumu Hyodo
,
Fumio Seki
,
Kazuhiro Fukuda
,
K. Tashiro
,
Yuki Kitai
,
Yukiko Akahori
,
Hideko Watabe
,
Hiroshi Katoh
,
Rikuto Osaki
,
Daisuke Takaya
,
Norihito Kawashita
,
Hideo Fukuhara
,
Satoshi Ikegame
,
Tomoki Yoshikawa
,
Eun‐Sil Park
,
Shigeru Morikawa
,
Ryoji Yamaguchi
,
Benhur Lee
,
Katsumi Maenaka
,
Tsuyoshi Shirai
,
Kaori Fukuzawa
,
Shigenori Tanaka
,
Makoto Takeda
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1371/journal.ppat.1012990
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1371/journal.ppat.1012990
Morbilliviruses, including measles virus (MV), canine distemper virus (CDV), peste des petits ruminants virus, and cetacean morbillivirus pose a significant threat to humans and animals. While the host range of morbilliviruses is generally well-defined, cross-species transmission events with significant mortality have also been reported. Their entry into immune cells, the primary targets of morbilliviruses, relies on the signaling lymphocytic activation molecule (SLAM), also known as SLAMF1 or CD150. In this study, we hypothesize that the ability of morbilliviruses to utilize heterologous SLAM receptors stems from evolutionarily conserved structural determinants within the SLAM protein and that minimal genetic changes in the viral receptor-binding H protein can enable adaptation to novel hosts. To test this, we systematically assessed SLAM utilization and adaptation by diverse morbilliviruses. We found that most morbilliviruses efficiently utilize SLAM from multiple host species, including Myotis bat SLAM, but not human SLAM. Only MV could efficiently utilize human SLAM. Additionally, unlike other morbilliviruses, MV utilized Myotis bat SLAM inefficiently. As an example of morbillivirus adaptation to non-host animal SLAM, we conducted an MV adaptation experiment with Myotis bat SLAM. We demonstrated that MV readily adapted to utilize Myotis bat SLAM by acquiring a single N187Y mutation in its hemagglutinin protein. Notably, hypothetical ancestral SLAMs acted as universal receptors for all morbilliviruses. These results reinforced that morbillivirus receptor usage is primarily supported by evolutionarily conserved structural features of SLAM, highlighting a molecular basis that enables morbilliviruses to rapidly adapt to diverse animal SLAMs.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1371/journal.ppat.1012990
- OA Status
- gold
- Cited By
- 1
- References
- 69
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4411171565
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4411171565Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1371/journal.ppat.1012990Digital Object Identifier
- Title
-
Evolutionary and structural basis of SLAMF1 utilization in morbilliviruses—Implications for host range and cross-species transmissionWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-06-10Full publication date if available
- Authors
-
Ayumu Hyodo, Fumio Seki, Kazuhiro Fukuda, K. Tashiro, Yuki Kitai, Yukiko Akahori, Hideko Watabe, Hiroshi Katoh, Rikuto Osaki, Daisuke Takaya, Norihito Kawashita, Hideo Fukuhara, Satoshi Ikegame, Tomoki Yoshikawa, Eun‐Sil Park, Shigeru Morikawa, Ryoji Yamaguchi, Benhur Lee, Katsumi Maenaka, Tsuyoshi Shirai, Kaori Fukuzawa, Shigenori Tanaka, Makoto TakedaList of authors in order
- Landing page
-
https://doi.org/10.1371/journal.ppat.1012990Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1371/journal.ppat.1012990Direct OA link when available
- Concepts
-
Transmission (telecommunications), Host (biology), Range (aeronautics), Computer science, Biology, Computer network, Telecommunications, Ecology, Engineering, Aerospace engineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1Per-year citation counts (last 5 years)
- References (count)
-
69Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4411171565 |
|---|---|
| doi | https://doi.org/10.1371/journal.ppat.1012990 |
| ids.doi | https://doi.org/10.1371/journal.ppat.1012990 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40493685 |
| ids.openalex | https://openalex.org/W4411171565 |
| fwci | 4.6013505 |
| mesh[0].qualifier_ui | Q000378 |
| mesh[0].descriptor_ui | D000071177 |
| mesh[0].is_major_topic | True |
| mesh[0].qualifier_name | metabolism |
| mesh[0].descriptor_name | Signaling Lymphocytic Activation Molecule Family Member 1 |
| mesh[1].qualifier_ui | Q000235 |
| mesh[1].descriptor_ui | D000071177 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | genetics |
| mesh[1].descriptor_name | Signaling Lymphocytic Activation Molecule Family Member 1 |
| mesh[2].qualifier_ui | Q000737 |
| mesh[2].descriptor_ui | D000071177 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | chemistry |
| mesh[2].descriptor_name | Signaling Lymphocytic Activation Molecule Family Member 1 |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D000818 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Animals |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D006801 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Humans |
| mesh[5].qualifier_ui | Q000235 |
| mesh[5].descriptor_ui | D018103 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | genetics |
| mesh[5].descriptor_name | Morbillivirus |
| mesh[6].qualifier_ui | Q000378 |
| mesh[6].descriptor_ui | D018103 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | metabolism |
| mesh[6].descriptor_name | Morbillivirus |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D058507 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Host Specificity |
| mesh[8].qualifier_ui | Q000635 |
| mesh[8].descriptor_ui | D018185 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | transmission |
| mesh[8].descriptor_name | Morbillivirus Infections |
| mesh[9].qualifier_ui | Q000378 |
| mesh[9].descriptor_ui | D018185 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | metabolism |
| mesh[9].descriptor_name | Morbillivirus Infections |
| mesh[10].qualifier_ui | Q000821 |
| mesh[10].descriptor_ui | D018185 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | virology |
| mesh[10].descriptor_name | Morbillivirus Infections |
| mesh[11].qualifier_ui | Q000235 |
| mesh[11].descriptor_ui | D018185 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | genetics |
| mesh[11].descriptor_name | Morbillivirus Infections |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D019143 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Evolution, Molecular |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D004285 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Dogs |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D004217 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Distemper Virus, Canine |
| mesh[15].qualifier_ui | Q000378 |
| mesh[15].descriptor_ui | D011991 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | metabolism |
| mesh[15].descriptor_name | Receptors, Virus |
| mesh[16].qualifier_ui | Q000235 |
| mesh[16].descriptor_ui | D011991 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | genetics |
| mesh[16].descriptor_name | Receptors, Virus |
| type | article |
| title | Evolutionary and structural basis of SLAMF1 utilization in morbilliviruses—Implications for host range and cross-species transmission |
| awards[0].id | https://openalex.org/G3984283177 |
| awards[0].funder_id | https://openalex.org/F4320337355 |
| awards[0].display_name | |
| awards[0].funder_award_id | NIH R01 AI188431 |
| awards[0].funder_display_name | National Institute of Allergy and Infectious Diseases |
| awards[1].id | https://openalex.org/G3783691827 |
| awards[1].funder_id | https://openalex.org/F4320334764 |
| awards[1].display_name | |
| awards[1].funder_award_id | 23K21381 |
| awards[1].funder_display_name | Japan Society for the Promotion of Science |
| awards[2].id | https://openalex.org/G3439097497 |
| awards[2].funder_id | https://openalex.org/F4320311405 |
| awards[2].display_name | |
| awards[2].funder_award_id | 24wm0325063h0002 |
| awards[2].funder_display_name | Japan Agency for Medical Research and Development |
| biblio.issue | 6 |
| biblio.volume | 21 |
| biblio.last_page | e1012990 |
| biblio.first_page | e1012990 |
| topics[0].id | https://openalex.org/T11135 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2713 |
| topics[0].subfield.display_name | Epidemiology |
| topics[0].display_name | Virology and Viral Diseases |
| topics[1].id | https://openalex.org/T10166 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9997000098228455 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2739 |
| topics[1].subfield.display_name | Public Health, Environmental and Occupational Health |
| topics[1].display_name | Mosquito-borne diseases and control |
| topics[2].id | https://openalex.org/T12047 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9993000030517578 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2725 |
| topics[2].subfield.display_name | Infectious Diseases |
| topics[2].display_name | Viral Infections and Vectors |
| funders[0].id | https://openalex.org/F4320311405 |
| funders[0].ror | https://ror.org/004rtk039 |
| funders[0].display_name | Japan Agency for Medical Research and Development |
| funders[1].id | https://openalex.org/F4320334764 |
| funders[1].ror | https://ror.org/00hhkn466 |
| funders[1].display_name | Japan Society for the Promotion of Science |
| funders[2].id | https://openalex.org/F4320337355 |
| funders[2].ror | https://ror.org/043z4tv69 |
| funders[2].display_name | National Institute of Allergy and Infectious Diseases |
| is_xpac | False |
| apc_list.value | 2655 |
| apc_list.currency | USD |
| apc_list.value_usd | 2655 |
| apc_paid.value | 2655 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 2655 |
| concepts[0].id | https://openalex.org/C761482 |
| concepts[0].level | 2 |
| concepts[0].score | 0.6628889441490173 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q118093 |
| concepts[0].display_name | Transmission (telecommunications) |
| concepts[1].id | https://openalex.org/C126831891 |
| concepts[1].level | 2 |
| concepts[1].score | 0.5132903456687927 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q221673 |
| concepts[1].display_name | Host (biology) |
| concepts[2].id | https://openalex.org/C204323151 |
| concepts[2].level | 2 |
| concepts[2].score | 0.45587533712387085 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q905424 |
| concepts[2].display_name | Range (aeronautics) |
| concepts[3].id | https://openalex.org/C41008148 |
| concepts[3].level | 0 |
| concepts[3].score | 0.4118524491786957 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[3].display_name | Computer science |
| concepts[4].id | https://openalex.org/C86803240 |
| concepts[4].level | 0 |
| concepts[4].score | 0.39015698432922363 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[4].display_name | Biology |
| concepts[5].id | https://openalex.org/C31258907 |
| concepts[5].level | 1 |
| concepts[5].score | 0.37248292565345764 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q1301371 |
| concepts[5].display_name | Computer network |
| concepts[6].id | https://openalex.org/C76155785 |
| concepts[6].level | 1 |
| concepts[6].score | 0.15861636400222778 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q418 |
| concepts[6].display_name | Telecommunications |
| concepts[7].id | https://openalex.org/C18903297 |
| concepts[7].level | 1 |
| concepts[7].score | 0.10813239216804504 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7150 |
| concepts[7].display_name | Ecology |
| concepts[8].id | https://openalex.org/C127413603 |
| concepts[8].level | 0 |
| concepts[8].score | 0.08787137269973755 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q11023 |
| concepts[8].display_name | Engineering |
| concepts[9].id | https://openalex.org/C146978453 |
| concepts[9].level | 1 |
| concepts[9].score | 0.0 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q3798668 |
| concepts[9].display_name | Aerospace engineering |
| keywords[0].id | https://openalex.org/keywords/transmission |
| keywords[0].score | 0.6628889441490173 |
| keywords[0].display_name | Transmission (telecommunications) |
| keywords[1].id | https://openalex.org/keywords/host |
| keywords[1].score | 0.5132903456687927 |
| keywords[1].display_name | Host (biology) |
| keywords[2].id | https://openalex.org/keywords/range |
| keywords[2].score | 0.45587533712387085 |
| keywords[2].display_name | Range (aeronautics) |
| keywords[3].id | https://openalex.org/keywords/computer-science |
| keywords[3].score | 0.4118524491786957 |
| keywords[3].display_name | Computer science |
| keywords[4].id | https://openalex.org/keywords/biology |
| keywords[4].score | 0.39015698432922363 |
| keywords[4].display_name | Biology |
| keywords[5].id | https://openalex.org/keywords/computer-network |
| keywords[5].score | 0.37248292565345764 |
| keywords[5].display_name | Computer network |
| keywords[6].id | https://openalex.org/keywords/telecommunications |
| keywords[6].score | 0.15861636400222778 |
| keywords[6].display_name | Telecommunications |
| keywords[7].id | https://openalex.org/keywords/ecology |
| keywords[7].score | 0.10813239216804504 |
| keywords[7].display_name | Ecology |
| keywords[8].id | https://openalex.org/keywords/engineering |
| keywords[8].score | 0.08787137269973755 |
| keywords[8].display_name | Engineering |
| language | en |
| locations[0].id | doi:10.1371/journal.ppat.1012990 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2004986 |
| locations[0].source.issn | 1553-7366, 1553-7374 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1553-7366 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | PLoS Pathogens |
| locations[0].source.host_organization | https://openalex.org/P4310315706 |
| locations[0].source.host_organization_name | Public Library of Science |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310315706 |
| locations[0].source.host_organization_lineage_names | Public Library of Science |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | PLOS Pathogens |
| locations[0].landing_page_url | https://doi.org/10.1371/journal.ppat.1012990 |
| locations[1].id | pmid:40493685 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | PLoS pathogens |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40493685 |
| locations[2].id | pmh:oai:doaj.org/article:004d01d12f6648cf953bdb62a813ec59 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | PLoS Pathogens, Vol 21, Iss 6, p e1012990 (2025) |
| locations[2].landing_page_url | https://doaj.org/article/004d01d12f6648cf953bdb62a813ec59 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5116322482 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Ayumu Hyodo |
| authorships[0].countries | JP |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I74801974 |
| authorships[0].affiliations[0].raw_affiliation_string | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[0].institutions[0].id | https://openalex.org/I74801974 |
| authorships[0].institutions[0].ror | https://ror.org/057zh3y96 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I74801974 |
| authorships[0].institutions[0].country_code | JP |
| authorships[0].institutions[0].display_name | The University of Tokyo |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Ayumu Hyodo |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[1].author.id | https://openalex.org/A5054435575 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-6144-468X |
| authorships[1].author.display_name | Fumio Seki |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I1299303238 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Virology 3, National Institute of Infectious Diseases, Musashimurayama, Tokyo, Japan. |
| authorships[1].institutions[0].id | https://openalex.org/I1299303238 |
| authorships[1].institutions[0].ror | https://ror.org/01cwqze88 |
| authorships[1].institutions[0].type | government |
| authorships[1].institutions[0].lineage | https://openalex.org/I1299022934, https://openalex.org/I1299303238 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | National Institutes of Health |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Fumio Seki |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Virology 3, National Institute of Infectious Diseases, Musashimurayama, Tokyo, Japan. |
| authorships[2].author.id | https://openalex.org/A5068255029 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-2999-5542 |
| authorships[2].author.display_name | Kazuhiro Fukuda |
| authorships[2].countries | JP |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I65837984 |
| authorships[2].affiliations[0].raw_affiliation_string | Graduate School of System Informatics, Kobe University, Kobe, Hyogo, Japan. |
| authorships[2].institutions[0].id | https://openalex.org/I65837984 |
| authorships[2].institutions[0].ror | https://ror.org/03tgsfw79 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I65837984 |
| authorships[2].institutions[0].country_code | JP |
| authorships[2].institutions[0].display_name | Kobe University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Kento Fukuda |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Graduate School of System Informatics, Kobe University, Kobe, Hyogo, Japan. |
| authorships[3].author.id | https://openalex.org/A5005086660 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-2133-7115 |
| authorships[3].author.display_name | K. Tashiro |
| authorships[3].countries | JP |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I74801974 |
| authorships[3].affiliations[0].raw_affiliation_string | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[3].affiliations[1].institution_ids | https://openalex.org/I104946051 |
| authorships[3].affiliations[1].raw_affiliation_string | Department of Veterinary Medicine, Nihon University, Fujisawa, Kanagawa, Japan. |
| authorships[3].institutions[0].id | https://openalex.org/I104946051 |
| authorships[3].institutions[0].ror | https://ror.org/05jk51a88 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I104946051 |
| authorships[3].institutions[0].country_code | JP |
| authorships[3].institutions[0].display_name | Nihon University |
| authorships[3].institutions[1].id | https://openalex.org/I74801974 |
| authorships[3].institutions[1].ror | https://ror.org/057zh3y96 |
| authorships[3].institutions[1].type | education |
| authorships[3].institutions[1].lineage | https://openalex.org/I74801974 |
| authorships[3].institutions[1].country_code | JP |
| authorships[3].institutions[1].display_name | The University of Tokyo |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Kaede Tashiro |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Veterinary Medicine, Nihon University, Fujisawa, Kanagawa, Japan., Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[4].author.id | https://openalex.org/A5014177719 |
| authorships[4].author.orcid | https://orcid.org/0000-0003-3271-6807 |
| authorships[4].author.display_name | Yuki Kitai |
| authorships[4].countries | JP |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I74801974 |
| authorships[4].affiliations[0].raw_affiliation_string | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[4].institutions[0].id | https://openalex.org/I74801974 |
| authorships[4].institutions[0].ror | https://ror.org/057zh3y96 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I74801974 |
| authorships[4].institutions[0].country_code | JP |
| authorships[4].institutions[0].display_name | The University of Tokyo |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Yuki Kitai |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[5].author.id | https://openalex.org/A5113709636 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Yukiko Akahori |
| authorships[5].countries | JP |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I74801974 |
| authorships[5].affiliations[0].raw_affiliation_string | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[5].institutions[0].id | https://openalex.org/I74801974 |
| authorships[5].institutions[0].ror | https://ror.org/057zh3y96 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I74801974 |
| authorships[5].institutions[0].country_code | JP |
| authorships[5].institutions[0].display_name | The University of Tokyo |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Yukiko Akahori |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[6].author.id | https://openalex.org/A5090222568 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Hideko Watabe |
| authorships[6].countries | JP |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I74801974 |
| authorships[6].affiliations[0].raw_affiliation_string | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[6].institutions[0].id | https://openalex.org/I74801974 |
| authorships[6].institutions[0].ror | https://ror.org/057zh3y96 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I74801974 |
| authorships[6].institutions[0].country_code | JP |
| authorships[6].institutions[0].display_name | The University of Tokyo |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Hideko Watabe |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[7].author.id | https://openalex.org/A5051422649 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-3864-1538 |
| authorships[7].author.display_name | Hiroshi Katoh |
| authorships[7].countries | JP |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I74801974 |
| authorships[7].affiliations[0].raw_affiliation_string | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[7].institutions[0].id | https://openalex.org/I74801974 |
| authorships[7].institutions[0].ror | https://ror.org/057zh3y96 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I74801974 |
| authorships[7].institutions[0].country_code | JP |
| authorships[7].institutions[0].display_name | The University of Tokyo |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Hiroshi Katoh |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[8].author.id | https://openalex.org/A5116322483 |
| authorships[8].author.orcid | |
| authorships[8].author.display_name | Rikuto Osaki |
| authorships[8].countries | JP |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I98285908 |
| authorships[8].affiliations[0].raw_affiliation_string | Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. |
| authorships[8].institutions[0].id | https://openalex.org/I98285908 |
| authorships[8].institutions[0].ror | https://ror.org/035t8zc32 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I98285908 |
| authorships[8].institutions[0].country_code | JP |
| authorships[8].institutions[0].display_name | The University of Osaka |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Rikuto Osaki |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. |
| authorships[9].author.id | https://openalex.org/A5063060714 |
| authorships[9].author.orcid | https://orcid.org/0000-0001-6020-8151 |
| authorships[9].author.display_name | Daisuke Takaya |
| authorships[9].countries | JP |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I98285908 |
| authorships[9].affiliations[0].raw_affiliation_string | Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. |
| authorships[9].institutions[0].id | https://openalex.org/I98285908 |
| authorships[9].institutions[0].ror | https://ror.org/035t8zc32 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I98285908 |
| authorships[9].institutions[0].country_code | JP |
| authorships[9].institutions[0].display_name | The University of Osaka |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Daisuke Takaya |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. |
| authorships[10].author.id | https://openalex.org/A5084497550 |
| authorships[10].author.orcid | https://orcid.org/0000-0002-1740-7232 |
| authorships[10].author.display_name | Norihito Kawashita |
| authorships[10].countries | JP |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I916559398 |
| authorships[10].affiliations[0].raw_affiliation_string | School of Science and Engineering, Kindai University, Higashi-osaka, Osaka, Japan. |
| authorships[10].institutions[0].id | https://openalex.org/I916559398 |
| authorships[10].institutions[0].ror | https://ror.org/05kt9ap64 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I916559398 |
| authorships[10].institutions[0].country_code | JP |
| authorships[10].institutions[0].display_name | Kindai University |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Norihito Kawashita |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | School of Science and Engineering, Kindai University, Higashi-osaka, Osaka, Japan. |
| authorships[11].author.id | https://openalex.org/A5085468767 |
| authorships[11].author.orcid | https://orcid.org/0000-0002-7035-8206 |
| authorships[11].author.display_name | Hideo Fukuhara |
| authorships[11].countries | JP |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I205349734 |
| authorships[11].affiliations[0].raw_affiliation_string | International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan. |
| authorships[11].institutions[0].id | https://openalex.org/I205349734 |
| authorships[11].institutions[0].ror | https://ror.org/02e16g702 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I205349734 |
| authorships[11].institutions[0].country_code | JP |
| authorships[11].institutions[0].display_name | Hokkaido University |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Hideo Fukuhara |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan. |
| authorships[12].author.id | https://openalex.org/A5065664923 |
| authorships[12].author.orcid | https://orcid.org/0000-0002-8183-3527 |
| authorships[12].author.display_name | Satoshi Ikegame |
| authorships[12].countries | JP, US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I135598925 |
| authorships[12].affiliations[0].raw_affiliation_string | Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. |
| authorships[12].affiliations[1].institution_ids | https://openalex.org/I98704320 |
| authorships[12].affiliations[1].raw_affiliation_string | Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. |
| authorships[12].institutions[0].id | https://openalex.org/I135598925 |
| authorships[12].institutions[0].ror | https://ror.org/00p4k0j84 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I135598925 |
| authorships[12].institutions[0].country_code | JP |
| authorships[12].institutions[0].display_name | Kyushu University |
| authorships[12].institutions[1].id | https://openalex.org/I98704320 |
| authorships[12].institutions[1].ror | https://ror.org/04a9tmd77 |
| authorships[12].institutions[1].type | education |
| authorships[12].institutions[1].lineage | https://openalex.org/I1320796813, https://openalex.org/I98704320 |
| authorships[12].institutions[1].country_code | US |
| authorships[12].institutions[1].display_name | Icahn School of Medicine at Mount Sinai |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Satoshi Ikegame |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. |
| authorships[13].author.id | https://openalex.org/A5031666867 |
| authorships[13].author.orcid | https://orcid.org/0000-0001-7601-4036 |
| authorships[13].author.display_name | Tomoki Yoshikawa |
| authorships[13].countries | JP |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I4210086300 |
| authorships[13].affiliations[0].raw_affiliation_string | Department of Virology 1, National Institute of Infectious Diseases, Musashimurayama, Tokyo, Japan. |
| authorships[13].institutions[0].id | https://openalex.org/I4210086300 |
| authorships[13].institutions[0].ror | https://ror.org/001ggbx22 |
| authorships[13].institutions[0].type | government |
| authorships[13].institutions[0].lineage | https://openalex.org/I1333985979, https://openalex.org/I4210086300 |
| authorships[13].institutions[0].country_code | JP |
| authorships[13].institutions[0].display_name | National Institute of Infectious Diseases |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Tomoki Yoshikawa |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Department of Virology 1, National Institute of Infectious Diseases, Musashimurayama, Tokyo, Japan. |
| authorships[14].author.id | https://openalex.org/A5101888751 |
| authorships[14].author.orcid | https://orcid.org/0000-0001-6795-0025 |
| authorships[14].author.display_name | Eun‐Sil Park |
| authorships[14].countries | JP |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I4210086300 |
| authorships[14].affiliations[0].raw_affiliation_string | Division of Experimental Animal Research, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan. |
| authorships[14].institutions[0].id | https://openalex.org/I4210086300 |
| authorships[14].institutions[0].ror | https://ror.org/001ggbx22 |
| authorships[14].institutions[0].type | government |
| authorships[14].institutions[0].lineage | https://openalex.org/I1333985979, https://openalex.org/I4210086300 |
| authorships[14].institutions[0].country_code | JP |
| authorships[14].institutions[0].display_name | National Institute of Infectious Diseases |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Park Eunsil |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Division of Experimental Animal Research, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan. |
| authorships[15].author.id | https://openalex.org/A5035518142 |
| authorships[15].author.orcid | https://orcid.org/0000-0001-6249-6716 |
| authorships[15].author.display_name | Shigeru Morikawa |
| authorships[15].countries | JP |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I136446963 |
| authorships[15].affiliations[0].raw_affiliation_string | Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime, Japan. |
| authorships[15].affiliations[1].institution_ids | https://openalex.org/I4210086300 |
| authorships[15].affiliations[1].raw_affiliation_string | Division of Experimental Animal Research, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan. |
| authorships[15].institutions[0].id | https://openalex.org/I4210086300 |
| authorships[15].institutions[0].ror | https://ror.org/001ggbx22 |
| authorships[15].institutions[0].type | government |
| authorships[15].institutions[0].lineage | https://openalex.org/I1333985979, https://openalex.org/I4210086300 |
| authorships[15].institutions[0].country_code | JP |
| authorships[15].institutions[0].display_name | National Institute of Infectious Diseases |
| authorships[15].institutions[1].id | https://openalex.org/I136446963 |
| authorships[15].institutions[1].ror | https://ror.org/05aevyc10 |
| authorships[15].institutions[1].type | education |
| authorships[15].institutions[1].lineage | https://openalex.org/I136446963 |
| authorships[15].institutions[1].country_code | JP |
| authorships[15].institutions[1].display_name | Okayama University of Science |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Shigeru Morikawa |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Division of Experimental Animal Research, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan., Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime, Japan. |
| authorships[16].author.id | https://openalex.org/A5027803959 |
| authorships[16].author.orcid | https://orcid.org/0000-0002-8409-8505 |
| authorships[16].author.display_name | Ryoji Yamaguchi |
| authorships[16].countries | JP |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I118574687 |
| authorships[16].affiliations[0].raw_affiliation_string | Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan. |
| authorships[16].institutions[0].id | https://openalex.org/I118574687 |
| authorships[16].institutions[0].ror | https://ror.org/0447kww10 |
| authorships[16].institutions[0].type | education |
| authorships[16].institutions[0].lineage | https://openalex.org/I118574687 |
| authorships[16].institutions[0].country_code | JP |
| authorships[16].institutions[0].display_name | University of Miyazaki |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Ryoji Yamaguchi |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan. |
| authorships[17].author.id | https://openalex.org/A5070606892 |
| authorships[17].author.orcid | https://orcid.org/0000-0003-0760-1709 |
| authorships[17].author.display_name | Benhur Lee |
| authorships[17].countries | US |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I98704320 |
| authorships[17].affiliations[0].raw_affiliation_string | Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. |
| authorships[17].institutions[0].id | https://openalex.org/I98704320 |
| authorships[17].institutions[0].ror | https://ror.org/04a9tmd77 |
| authorships[17].institutions[0].type | education |
| authorships[17].institutions[0].lineage | https://openalex.org/I1320796813, https://openalex.org/I98704320 |
| authorships[17].institutions[0].country_code | US |
| authorships[17].institutions[0].display_name | Icahn School of Medicine at Mount Sinai |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | Benhur Lee |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. |
| authorships[18].author.id | https://openalex.org/A5042597121 |
| authorships[18].author.orcid | https://orcid.org/0000-0002-5459-521X |
| authorships[18].author.display_name | Katsumi Maenaka |
| authorships[18].countries | JP |
| authorships[18].affiliations[0].institution_ids | https://openalex.org/I205349734, https://openalex.org/I21851649 |
| authorships[18].affiliations[0].raw_affiliation_string | Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan. |
| authorships[18].institutions[0].id | https://openalex.org/I21851649 |
| authorships[18].institutions[0].ror | https://ror.org/02qh3e530 |
| authorships[18].institutions[0].type | education |
| authorships[18].institutions[0].lineage | https://openalex.org/I21851649 |
| authorships[18].institutions[0].country_code | JP |
| authorships[18].institutions[0].display_name | Hokkaido Pharmaceutical University |
| authorships[18].institutions[1].id | https://openalex.org/I205349734 |
| authorships[18].institutions[1].ror | https://ror.org/02e16g702 |
| authorships[18].institutions[1].type | education |
| authorships[18].institutions[1].lineage | https://openalex.org/I205349734 |
| authorships[18].institutions[1].country_code | JP |
| authorships[18].institutions[1].display_name | Hokkaido University |
| authorships[18].author_position | middle |
| authorships[18].raw_author_name | Katsumi Maenaka |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan. |
| authorships[19].author.id | https://openalex.org/A5055548527 |
| authorships[19].author.orcid | |
| authorships[19].author.display_name | Tsuyoshi Shirai |
| authorships[19].countries | JP |
| authorships[19].affiliations[0].institution_ids | https://openalex.org/I194335595 |
| authorships[19].affiliations[0].raw_affiliation_string | Faculty of Bioscience, Nagahama Institute of BioScience and Technology, Nagahama, Shiga, Japan. |
| authorships[19].institutions[0].id | https://openalex.org/I194335595 |
| authorships[19].institutions[0].ror | https://ror.org/03m5fme96 |
| authorships[19].institutions[0].type | education |
| authorships[19].institutions[0].lineage | https://openalex.org/I194335595 |
| authorships[19].institutions[0].country_code | JP |
| authorships[19].institutions[0].display_name | Nagahama Institute of Bio-Science and Technology |
| authorships[19].author_position | middle |
| authorships[19].raw_author_name | Tsuyoshi Shirai |
| authorships[19].is_corresponding | False |
| authorships[19].raw_affiliation_strings | Faculty of Bioscience, Nagahama Institute of BioScience and Technology, Nagahama, Shiga, Japan. |
| authorships[20].author.id | https://openalex.org/A5079773397 |
| authorships[20].author.orcid | https://orcid.org/0000-0001-5357-8250 |
| authorships[20].author.display_name | Kaori Fukuzawa |
| authorships[20].countries | JP |
| authorships[20].affiliations[0].institution_ids | https://openalex.org/I98285908 |
| authorships[20].affiliations[0].raw_affiliation_string | Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. |
| authorships[20].institutions[0].id | https://openalex.org/I98285908 |
| authorships[20].institutions[0].ror | https://ror.org/035t8zc32 |
| authorships[20].institutions[0].type | education |
| authorships[20].institutions[0].lineage | https://openalex.org/I98285908 |
| authorships[20].institutions[0].country_code | JP |
| authorships[20].institutions[0].display_name | The University of Osaka |
| authorships[20].author_position | middle |
| authorships[20].raw_author_name | Kaori Fukuzawa |
| authorships[20].is_corresponding | False |
| authorships[20].raw_affiliation_strings | Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. |
| authorships[21].author.id | https://openalex.org/A5106133798 |
| authorships[21].author.orcid | |
| authorships[21].author.display_name | Shigenori Tanaka |
| authorships[21].countries | JP |
| authorships[21].affiliations[0].institution_ids | https://openalex.org/I65837984 |
| authorships[21].affiliations[0].raw_affiliation_string | Graduate School of System Informatics, Kobe University, Kobe, Hyogo, Japan. |
| authorships[21].institutions[0].id | https://openalex.org/I65837984 |
| authorships[21].institutions[0].ror | https://ror.org/03tgsfw79 |
| authorships[21].institutions[0].type | education |
| authorships[21].institutions[0].lineage | https://openalex.org/I65837984 |
| authorships[21].institutions[0].country_code | JP |
| authorships[21].institutions[0].display_name | Kobe University |
| authorships[21].author_position | middle |
| authorships[21].raw_author_name | Shigenori Tanaka |
| authorships[21].is_corresponding | False |
| authorships[21].raw_affiliation_strings | Graduate School of System Informatics, Kobe University, Kobe, Hyogo, Japan. |
| authorships[22].author.id | https://openalex.org/A5078437261 |
| authorships[22].author.orcid | https://orcid.org/0000-0002-8194-7727 |
| authorships[22].author.display_name | Makoto Takeda |
| authorships[22].countries | JP |
| authorships[22].affiliations[0].institution_ids | https://openalex.org/I74801974 |
| authorships[22].affiliations[0].raw_affiliation_string | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[22].affiliations[1].institution_ids | https://openalex.org/I74801974 |
| authorships[22].affiliations[1].raw_affiliation_string | Pandemic Preparedness, Infection and Advanced Research Center, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| authorships[22].institutions[0].id | https://openalex.org/I74801974 |
| authorships[22].institutions[0].ror | https://ror.org/057zh3y96 |
| authorships[22].institutions[0].type | education |
| authorships[22].institutions[0].lineage | https://openalex.org/I74801974 |
| authorships[22].institutions[0].country_code | JP |
| authorships[22].institutions[0].display_name | The University of Tokyo |
| authorships[22].author_position | last |
| authorships[22].raw_author_name | Makoto Takeda |
| authorships[22].is_corresponding | False |
| authorships[22].raw_affiliation_strings | Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan., Pandemic Preparedness, Infection and Advanced Research Center, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1371/journal.ppat.1012990 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Evolutionary and structural basis of SLAMF1 utilization in morbilliviruses—Implications for host range and cross-species transmission |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11135 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2713 |
| primary_topic.subfield.display_name | Epidemiology |
| primary_topic.display_name | Virology and Viral Diseases |
| related_works | https://openalex.org/W4391375266, https://openalex.org/W2082860237, https://openalex.org/W2119695867, https://openalex.org/W2130076355, https://openalex.org/W1990804418, https://openalex.org/W1993764875, https://openalex.org/W2046158694, https://openalex.org/W2788277189, https://openalex.org/W2013243191, https://openalex.org/W1971568933 |
| cited_by_count | 1 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1371/journal.ppat.1012990 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2004986 |
| best_oa_location.source.issn | 1553-7366, 1553-7374 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1553-7366 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | PLoS Pathogens |
| best_oa_location.source.host_organization | https://openalex.org/P4310315706 |
| best_oa_location.source.host_organization_name | Public Library of Science |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310315706 |
| best_oa_location.source.host_organization_lineage_names | Public Library of Science |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | PLOS Pathogens |
| best_oa_location.landing_page_url | https://doi.org/10.1371/journal.ppat.1012990 |
| primary_location.id | doi:10.1371/journal.ppat.1012990 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2004986 |
| primary_location.source.issn | 1553-7366, 1553-7374 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1553-7366 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | PLoS Pathogens |
| primary_location.source.host_organization | https://openalex.org/P4310315706 |
| primary_location.source.host_organization_name | Public Library of Science |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310315706 |
| primary_location.source.host_organization_lineage_names | Public Library of Science |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | PLOS Pathogens |
| primary_location.landing_page_url | https://doi.org/10.1371/journal.ppat.1012990 |
| publication_date | 2025-06-10 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W3019605001, https://openalex.org/W4297183650, https://openalex.org/W4368373848, https://openalex.org/W4283795250, https://openalex.org/W4392912714, https://openalex.org/W3175307859, https://openalex.org/W2141189517, https://openalex.org/W2036844504, https://openalex.org/W2953920952, https://openalex.org/W1997075862, https://openalex.org/W2968544572, https://openalex.org/W2007859857, https://openalex.org/W1988239113, https://openalex.org/W1980143859, https://openalex.org/W2979595210, https://openalex.org/W1972949627, https://openalex.org/W1894319479, https://openalex.org/W2043279939, https://openalex.org/W4281787267, https://openalex.org/W3097542584, https://openalex.org/W4311290151, https://openalex.org/W1992652788, https://openalex.org/W3013432488, https://openalex.org/W2023101811, https://openalex.org/W2022891312, https://openalex.org/W1971663743, https://openalex.org/W2035942037, https://openalex.org/W2100255826, https://openalex.org/W2120956264, https://openalex.org/W2094715395, https://openalex.org/W1963681795, https://openalex.org/W2479316378, https://openalex.org/W2021119981, https://openalex.org/W2001908648, https://openalex.org/W2163769709, https://openalex.org/W1968705514, https://openalex.org/W1993118426, https://openalex.org/W3135196812, https://openalex.org/W2110335151, https://openalex.org/W3036478712, https://openalex.org/W2913826466, https://openalex.org/W2890222269, https://openalex.org/W2166573430, https://openalex.org/W2042866972, https://openalex.org/W6650345917, https://openalex.org/W2281828676, https://openalex.org/W2115110988, https://openalex.org/W2065906421, https://openalex.org/W2032749377, https://openalex.org/W1591890160, https://openalex.org/W2048162805, https://openalex.org/W2099336219, https://openalex.org/W2168230192, https://openalex.org/W2079350688, https://openalex.org/W2059626882, https://openalex.org/W2127322768, https://openalex.org/W2799524357, https://openalex.org/W2095148640, https://openalex.org/W4251872734, https://openalex.org/W3206866461, https://openalex.org/W2019322974, https://openalex.org/W2004997596, https://openalex.org/W3122608869, https://openalex.org/W3177828909, https://openalex.org/W4281790889, https://openalex.org/W1981021420, https://openalex.org/W1976499671, https://openalex.org/W2989052455, https://openalex.org/W1999446871 |
| referenced_works_count | 69 |
| abstract_inverted_index.H | 102 |
| abstract_inverted_index.a | 18, 193, 230 |
| abstract_inverted_index.As | 160 |
| abstract_inverted_index.In | 68 |
| abstract_inverted_index.MV | 144, 154, 173, 183 |
| abstract_inverted_index.To | 110 |
| abstract_inverted_index.We | 123, 180 |
| abstract_inverted_index.an | 161, 172 |
| abstract_inverted_index.as | 64, 206 |
| abstract_inverted_index.by | 120, 191, 222 |
| abstract_inverted_index.in | 98, 197 |
| abstract_inverted_index.is | 31, 219 |
| abstract_inverted_index.of | 29, 52, 76, 163, 227 |
| abstract_inverted_index.on | 55 |
| abstract_inverted_index.or | 66 |
| abstract_inverted_index.to | 21, 78, 107, 166, 186, 236, 239 |
| abstract_inverted_index.we | 71, 113, 170 |
| abstract_inverted_index.all | 210 |
| abstract_inverted_index.and | 14, 23, 93, 118 |
| abstract_inverted_index.bat | 137, 157, 178, 189 |
| abstract_inverted_index.but | 139 |
| abstract_inverted_index.can | 104 |
| abstract_inverted_index.des | 10 |
| abstract_inverted_index.for | 209 |
| abstract_inverted_index.its | 198 |
| abstract_inverted_index.not | 140 |
| abstract_inverted_index.the | 26, 49, 56, 74, 90, 99 |
| abstract_inverted_index.Only | 143 |
| abstract_inverted_index.SLAM | 81, 91, 116, 130, 158, 190 |
| abstract_inverted_index.also | 41, 62 |
| abstract_inverted_index.been | 42 |
| abstract_inverted_index.from | 84, 131 |
| abstract_inverted_index.have | 40 |
| abstract_inverted_index.host | 27, 133 |
| abstract_inverted_index.into | 46 |
| abstract_inverted_index.most | 126 |
| abstract_inverted_index.pose | 17 |
| abstract_inverted_index.test | 111 |
| abstract_inverted_index.that | 73, 94, 125, 182, 215, 233 |
| abstract_inverted_index.this | 69 |
| abstract_inverted_index.with | 37, 176 |
| abstract_inverted_index.(MV), | 4 |
| abstract_inverted_index.N187Y | 195 |
| abstract_inverted_index.SLAM, | 138, 169, 228 |
| abstract_inverted_index.SLAM. | 142, 149, 179 |
| abstract_inverted_index.SLAMs | 204 |
| abstract_inverted_index.Their | 44 |
| abstract_inverted_index.These | 212 |
| abstract_inverted_index.While | 25 |
| abstract_inverted_index.acted | 205 |
| abstract_inverted_index.adapt | 238 |
| abstract_inverted_index.basis | 232 |
| abstract_inverted_index.could | 145 |
| abstract_inverted_index.entry | 45 |
| abstract_inverted_index.found | 124 |
| abstract_inverted_index.human | 141, 148 |
| abstract_inverted_index.known | 63 |
| abstract_inverted_index.novel | 108 |
| abstract_inverted_index.other | 152 |
| abstract_inverted_index.peste | 9 |
| abstract_inverted_index.range | 28 |
| abstract_inverted_index.stems | 83 |
| abstract_inverted_index.this, | 112 |
| abstract_inverted_index.usage | 218 |
| abstract_inverted_index.viral | 100 |
| abstract_inverted_index.virus | 3, 7 |
| abstract_inverted_index.(CDV), | 8 |
| abstract_inverted_index.CD150. | 67 |
| abstract_inverted_index.Myotis | 136, 156, 177, 188 |
| abstract_inverted_index.SLAMF1 | 65 |
| abstract_inverted_index.SLAMs. | 242 |
| abstract_inverted_index.animal | 168, 241 |
| abstract_inverted_index.canine | 5 |
| abstract_inverted_index.cells, | 48 |
| abstract_inverted_index.enable | 105 |
| abstract_inverted_index.events | 36 |
| abstract_inverted_index.hosts. | 109 |
| abstract_inverted_index.humans | 22 |
| abstract_inverted_index.immune | 47 |
| abstract_inverted_index.petits | 11 |
| abstract_inverted_index.relies | 54 |
| abstract_inverted_index.single | 194 |
| abstract_inverted_index.study, | 70 |
| abstract_inverted_index.threat | 20 |
| abstract_inverted_index.unlike | 151 |
| abstract_inverted_index.virus, | 13 |
| abstract_inverted_index.within | 89 |
| abstract_inverted_index.(SLAM), | 61 |
| abstract_inverted_index.ability | 75 |
| abstract_inverted_index.adapted | 185 |
| abstract_inverted_index.changes | 97 |
| abstract_inverted_index.diverse | 121, 240 |
| abstract_inverted_index.enables | 234 |
| abstract_inverted_index.example | 162 |
| abstract_inverted_index.genetic | 96 |
| abstract_inverted_index.measles | 2 |
| abstract_inverted_index.minimal | 95 |
| abstract_inverted_index.primary | 50 |
| abstract_inverted_index.protein | 92, 103 |
| abstract_inverted_index.rapidly | 237 |
| abstract_inverted_index.readily | 184 |
| abstract_inverted_index.results | 213 |
| abstract_inverted_index.targets | 51 |
| abstract_inverted_index.utilize | 79, 129, 147, 187 |
| abstract_inverted_index.Notably, | 201 |
| abstract_inverted_index.animals. | 24 |
| abstract_inverted_index.assessed | 115 |
| abstract_inverted_index.cetacean | 15 |
| abstract_inverted_index.features | 226 |
| abstract_inverted_index.molecule | 60 |
| abstract_inverted_index.multiple | 132 |
| abstract_inverted_index.mutation | 196 |
| abstract_inverted_index.non-host | 167 |
| abstract_inverted_index.protein. | 200 |
| abstract_inverted_index.receptor | 217 |
| abstract_inverted_index.species, | 134 |
| abstract_inverted_index.utilized | 155 |
| abstract_inverted_index.acquiring | 192 |
| abstract_inverted_index.ancestral | 203 |
| abstract_inverted_index.conducted | 171 |
| abstract_inverted_index.conserved | 86, 224 |
| abstract_inverted_index.distemper | 6 |
| abstract_inverted_index.generally | 32 |
| abstract_inverted_index.including | 1, 135 |
| abstract_inverted_index.molecular | 231 |
| abstract_inverted_index.mortality | 39 |
| abstract_inverted_index.primarily | 220 |
| abstract_inverted_index.receptors | 82, 208 |
| abstract_inverted_index.reported. | 43 |
| abstract_inverted_index.ruminants | 12 |
| abstract_inverted_index.signaling | 57 |
| abstract_inverted_index.supported | 221 |
| abstract_inverted_index.universal | 207 |
| abstract_inverted_index.activation | 59 |
| abstract_inverted_index.adaptation | 106, 119, 165, 174 |
| abstract_inverted_index.experiment | 175 |
| abstract_inverted_index.reinforced | 214 |
| abstract_inverted_index.structural | 87, 225 |
| abstract_inverted_index.efficiently | 128, 146 |
| abstract_inverted_index.hypothesize | 72 |
| abstract_inverted_index.lymphocytic | 58 |
| abstract_inverted_index.significant | 19, 38 |
| abstract_inverted_index.utilization | 117 |
| abstract_inverted_index.demonstrated | 181 |
| abstract_inverted_index.determinants | 88 |
| abstract_inverted_index.heterologous | 80 |
| abstract_inverted_index.highlighting | 229 |
| abstract_inverted_index.hypothetical | 202 |
| abstract_inverted_index.transmission | 35 |
| abstract_inverted_index.Additionally, | 150 |
| abstract_inverted_index.cross-species | 34 |
| abstract_inverted_index.hemagglutinin | 199 |
| abstract_inverted_index.morbillivirus | 16, 164, 216 |
| abstract_inverted_index.well-defined, | 33 |
| abstract_inverted_index.evolutionarily | 85, 223 |
| abstract_inverted_index.inefficiently. | 159 |
| abstract_inverted_index.systematically | 114 |
| abstract_inverted_index.morbilliviruses | 30, 77, 127, 235 |
| abstract_inverted_index.Morbilliviruses, | 0 |
| abstract_inverted_index.morbilliviruses, | 53, 153 |
| abstract_inverted_index.morbilliviruses. | 122, 211 |
| abstract_inverted_index.receptor-binding | 101 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 23 |
| citation_normalized_percentile.value | 0.87502331 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |