Evolving strategies in microbe identification—a comprehensive review of biochemical, MALDI-TOF MS and molecular testing methods Article Swipe
Sophie Arbefeville
,
Tristan T. Timbrook
,
Cherilyn D. Garner
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/jac/dkae275
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/jac/dkae275
Detection and identification of microorganisms are the first steps to guide susceptibility testing and enable clinicians to confirm diseases and guide therapy. The faster the pathogen identification is determined, the quicker the appropriate treatment can be started. In the clinical microbiology laboratory, multiple methodologies can be used to identify organisms, such as traditional biochemical testing or more recent methods like MALDI TOF MS and nucleic acid detection/identification assays. Each of these techniques has advantages and limitations, and clinical laboratories need to determine which methodology is best suited to their particular setting in terms of clinical needs, availability of technical expertise and cost. This article presents a concise review of the history, utilization, advantages and limitations of the main methods used for identifying microorganisms in microbiology laboratories.
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- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1093/jac/dkae275
- OA Status
- green
- Cited By
- 12
- References
- 58
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4402634392Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/jac/dkae275Digital Object Identifier
- Title
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Evolving strategies in microbe identification—a comprehensive review of biochemical, MALDI-TOF MS and molecular testing methodsWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-09-01Full publication date if available
- Authors
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Sophie Arbefeville, Tristan T. Timbrook, Cherilyn D. GarnerList of authors in order
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https://doi.org/10.1093/jac/dkae275Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
- OA URL
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https://www.ncbi.nlm.nih.gov/pmc/articles/11412244Direct OA link when available
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Identification (biology), Clinical microbiology, Computational biology, Pathogenic organism, Computer science, Microbiological Techniques, Biochemical engineering, Biology, Microbiology, Engineering, BotanyTop concepts (fields/topics) attached by OpenAlex
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12Total citation count in OpenAlex
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2025: 12Per-year citation counts (last 5 years)
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58Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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