Experimental Physiology
Exercise modality‐dependent mitochondrial respiratory capacity in satellite cells and conditioned serum‐induced responses in cultured myotubes
June 2025 • Takanaga Shirai, Hiroshi Shinkai, Riku Tanimura, Kazuki Uemichi, Shunsuke Sugiyama, Kohei Takeda, Yu Kitaoka, Tohru Takemasa
Abstract Exercise‐induced mitochondrial adaptations contribute to muscle function and metabolic health. We aimed to investigate the association of moderate‐intensity swimming (MOD) and high‐intensity interval training (HIIT) with mitochondrial function in skeletal muscle cells treated with exercise‐conditioned serum. Male ICR mice (7–8 weeks old) were assigned to the Sedentary, MOD or HIIT group. The MOD group underwent five sessions of 60 min. The HIIT group performed weighted high‐intensity swimming intervals. T…