Exhaustive 3D-QSAR analyses as a computational tool to explore the potency and selectivity profiles of thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDE7 inhibitors Article Swipe
Elena Cichero
,
Chiara Brullo
,
Olga Bruno
,
Paola Fossa
·
YOU?
·
· 2016
· Open Access
·
· DOI: https://doi.org/10.1039/c6ra12624c
YOU?
·
· 2016
· Open Access
·
· DOI: https://doi.org/10.1039/c6ra12624c
In the development of selective ligands binding to specific PDE isoforms, the ligand-based approach proved to be a useful tool to better investigate the potency and selectivity profiles of PDE7 inhibitors.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1039/c6ra12624c
- https://pubs.rsc.org/en/content/articlepdf/2016/ra/c6ra12624c
- OA Status
- hybrid
- Cited By
- 9
- References
- 38
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2467322542
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W2467322542Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1039/c6ra12624cDigital Object Identifier
- Title
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Exhaustive 3D-QSAR analyses as a computational tool to explore the potency and selectivity profiles of thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDE7 inhibitorsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2016Year of publication
- Publication date
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2016-01-01Full publication date if available
- Authors
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Elena Cichero, Chiara Brullo, Olga Bruno, Paola FossaList of authors in order
- Landing page
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https://doi.org/10.1039/c6ra12624cPublisher landing page
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https://pubs.rsc.org/en/content/articlepdf/2016/ra/c6ra12624cDirect link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://pubs.rsc.org/en/content/articlepdf/2016/ra/c6ra12624cDirect OA link when available
- Concepts
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Potency, Selectivity, Chemistry, Quantitative structure–activity relationship, Ligand (biochemistry), Gene isoform, Stereochemistry, Computational biology, Combinatorial chemistry, Biochemistry, In vitro, Biology, Gene, Receptor, CatalysisTop concepts (fields/topics) attached by OpenAlex
- Cited by
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9Total citation count in OpenAlex
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2022: 1, 2021: 1, 2018: 3, 2017: 3, 2016: 1Per-year citation counts (last 5 years)
- References (count)
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38Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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