Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial Article Swipe
Robert L. Cook
,
Veronica L. Richards
,
Joseph M. Gullett
,
Brenda Lerner
,
Zhi Zhou
,
Eric C. Porges
,
Yan Wang
,
Christopher W. Kahler
,
Nancy P. Barnett
,
Zhigang Li
,
Suresh Pallikkuth
,
Emmanuel Thomas
,
Allan Rodríguez
,
Kendall Bryant
,
Smita Ghare
,
Shirish Barve
,
Varan Govind
,
Jessy G. Dévieux
,
Ronald A. Cohen
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.2196/53684
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.2196/53684
Background Both alcohol consumption and HIV infection are associated with worse brain, cognitive, and clinical outcomes in older adults. However, the extent to which brain and cognitive dysfunction is reversible with reduction or cessation of drinking is unknown. Objective The 30-Day Challenge study was designed to determine whether reduction or cessation of drinking would be associated with improvements in cognition, reduction of systemic and brain inflammation, and improvement in HIV-related outcomes in adults with heavy drinking. Methods The study design was a mechanistic experimental trial, in which all participants received an alcohol reduction intervention followed by repeated assessments of behavioral and clinical outcomes. Persons were eligible if they were 45 years of age or older, had weekly alcohol consumption of 21 or more drinks (men) or 14 or more drinks (women), and were not at high risk of alcohol withdrawal. After a baseline assessment, participants received an intervention consisting of contingency management (money for nondrinking days) for at least 30 days followed by a brief motivational interview. After this, participants could either resume drinking or not. Study questionnaires, neurocognitive assessments, neuroimaging, and blood, urine, and stool samples were collected at baseline, 30 days, 90 days, and 1 year after enrollment. Results We enrolled 57 persons with heavy drinking who initiated the contingency management protocol (mean age 56 years, SD 4.6 years; 63%, n=36 male, 77%, n=44 Black, and 58%, n=33 people with HIV) of whom 50 completed 30-day follow-up and 43 the 90-day follow-up. The planned study procedures were interrupted and modified due to the COVID-19 pandemic of 2020-2021. Conclusions This was the first study seeking to assess changes in brain (neuroimaging) and cognition after alcohol intervention in nontreatment-seeking people with HIV together with people without HIV as controls. Study design strengths, limitations, and lessons for future study design considerations are discussed. Planned analyses are in progress, after which deidentified study data will be available for sharing. Trial Registration ClinicalTrials.gov NCT03353701; https://clinicaltrials.gov/study/NCT03353701 International Registered Report Identifier (IRRID) DERR1-10.2196/53684
Related Topics
Concepts
Medicine
Cognition
Clinical trial
Human immunodeficiency virus (HIV)
Alcohol consumption
Protocol (science)
Effects of sleep deprivation on cognitive performance
Randomized controlled trial
Cognitive decline
Psychiatry
Alcohol
Gerontology
Dementia
Internal medicine
Family medicine
Alternative medicine
Disease
Biochemistry
Pathology
Chemistry
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.2196/53684
- OA Status
- gold
- References
- 57
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4388523901
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4388523901Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.2196/53684Digital Object Identifier
- Title
-
Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical TrialWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-11-09Full publication date if available
- Authors
-
Robert L. Cook, Veronica L. Richards, Joseph M. Gullett, Brenda Lerner, Zhi Zhou, Eric C. Porges, Yan Wang, Christopher W. Kahler, Nancy P. Barnett, Zhigang Li, Suresh Pallikkuth, Emmanuel Thomas, Allan Rodríguez, Kendall Bryant, Smita Ghare, Shirish Barve, Varan Govind, Jessy G. Dévieux, Ronald A. CohenList of authors in order
- Landing page
-
https://doi.org/10.2196/53684Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.2196/53684Direct OA link when available
- Concepts
-
Medicine, Cognition, Clinical trial, Human immunodeficiency virus (HIV), Alcohol consumption, Protocol (science), Effects of sleep deprivation on cognitive performance, Randomized controlled trial, Cognitive decline, Psychiatry, Alcohol, Gerontology, Dementia, Internal medicine, Family medicine, Alternative medicine, Disease, Biochemistry, Pathology, ChemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
57Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4388523901 |
|---|---|
| doi | https://doi.org/10.2196/53684 |
| ids.doi | https://doi.org/10.2196/53684 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/38564243 |
| ids.openalex | https://openalex.org/W4388523901 |
| fwci | 0.0 |
| type | article |
| title | Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial |
| biblio.issue | |
| biblio.volume | 13 |
| biblio.last_page | e53684 |
| biblio.first_page | e53684 |
| topics[0].id | https://openalex.org/T13966 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9965000152587891 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2712 |
| topics[0].subfield.display_name | Endocrinology, Diabetes and Metabolism |
| topics[0].display_name | Neurological and metabolic disorders |
| topics[1].id | https://openalex.org/T10112 |
| topics[1].field.id | https://openalex.org/fields/24 |
| topics[1].field.display_name | Immunology and Microbiology |
| topics[1].score | 0.9952999949455261 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2406 |
| topics[1].subfield.display_name | Virology |
| topics[1].display_name | HIV Research and Treatment |
| topics[2].id | https://openalex.org/T11655 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9952999949455261 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2711 |
| topics[2].subfield.display_name | Emergency Medicine |
| topics[2].display_name | HIV-related health complications and treatments |
| is_xpac | False |
| apc_list.value | 1900 |
| apc_list.currency | USD |
| apc_list.value_usd | 1900 |
| apc_paid.value | 1900 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 1900 |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.7011824250221252 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C169900460 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6825340390205383 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q2200417 |
| concepts[1].display_name | Cognition |
| concepts[2].id | https://openalex.org/C535046627 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6652774214744568 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q30612 |
| concepts[2].display_name | Clinical trial |
| concepts[3].id | https://openalex.org/C3013748606 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6195708513259888 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q15787 |
| concepts[3].display_name | Human immunodeficiency virus (HIV) |
| concepts[4].id | https://openalex.org/C3019635848 |
| concepts[4].level | 3 |
| concepts[4].score | 0.5404132604598999 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q154 |
| concepts[4].display_name | Alcohol consumption |
| concepts[5].id | https://openalex.org/C2780385302 |
| concepts[5].level | 3 |
| concepts[5].score | 0.5037958025932312 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q367158 |
| concepts[5].display_name | Protocol (science) |
| concepts[6].id | https://openalex.org/C185711340 |
| concepts[6].level | 3 |
| concepts[6].score | 0.4369378089904785 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q5347381 |
| concepts[6].display_name | Effects of sleep deprivation on cognitive performance |
| concepts[7].id | https://openalex.org/C168563851 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4311670958995819 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1436668 |
| concepts[7].display_name | Randomized controlled trial |
| concepts[8].id | https://openalex.org/C2984863031 |
| concepts[8].level | 4 |
| concepts[8].score | 0.4291412830352783 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q83030 |
| concepts[8].display_name | Cognitive decline |
| concepts[9].id | https://openalex.org/C118552586 |
| concepts[9].level | 1 |
| concepts[9].score | 0.39621007442474365 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7867 |
| concepts[9].display_name | Psychiatry |
| concepts[10].id | https://openalex.org/C2781066024 |
| concepts[10].level | 2 |
| concepts[10].score | 0.32747042179107666 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q156 |
| concepts[10].display_name | Alcohol |
| concepts[11].id | https://openalex.org/C74909509 |
| concepts[11].level | 1 |
| concepts[11].score | 0.3262649178504944 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q10387 |
| concepts[11].display_name | Gerontology |
| concepts[12].id | https://openalex.org/C2779483572 |
| concepts[12].level | 3 |
| concepts[12].score | 0.19784143567085266 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q83030 |
| concepts[12].display_name | Dementia |
| concepts[13].id | https://openalex.org/C126322002 |
| concepts[13].level | 1 |
| concepts[13].score | 0.1821483075618744 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[13].display_name | Internal medicine |
| concepts[14].id | https://openalex.org/C512399662 |
| concepts[14].level | 1 |
| concepts[14].score | 0.1548984944820404 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q3505712 |
| concepts[14].display_name | Family medicine |
| concepts[15].id | https://openalex.org/C204787440 |
| concepts[15].level | 2 |
| concepts[15].score | 0.14945968985557556 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q188504 |
| concepts[15].display_name | Alternative medicine |
| concepts[16].id | https://openalex.org/C2779134260 |
| concepts[16].level | 2 |
| concepts[16].score | 0.10874050855636597 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q12136 |
| concepts[16].display_name | Disease |
| concepts[17].id | https://openalex.org/C55493867 |
| concepts[17].level | 1 |
| concepts[17].score | 0.0 |
| concepts[17].wikidata | https://www.wikidata.org/wiki/Q7094 |
| concepts[17].display_name | Biochemistry |
| concepts[18].id | https://openalex.org/C142724271 |
| concepts[18].level | 1 |
| concepts[18].score | 0.0 |
| concepts[18].wikidata | https://www.wikidata.org/wiki/Q7208 |
| concepts[18].display_name | Pathology |
| concepts[19].id | https://openalex.org/C185592680 |
| concepts[19].level | 0 |
| concepts[19].score | 0.0 |
| concepts[19].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[19].display_name | Chemistry |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.7011824250221252 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/cognition |
| keywords[1].score | 0.6825340390205383 |
| keywords[1].display_name | Cognition |
| keywords[2].id | https://openalex.org/keywords/clinical-trial |
| keywords[2].score | 0.6652774214744568 |
| keywords[2].display_name | Clinical trial |
| keywords[3].id | https://openalex.org/keywords/human-immunodeficiency-virus |
| keywords[3].score | 0.6195708513259888 |
| keywords[3].display_name | Human immunodeficiency virus (HIV) |
| keywords[4].id | https://openalex.org/keywords/alcohol-consumption |
| keywords[4].score | 0.5404132604598999 |
| keywords[4].display_name | Alcohol consumption |
| keywords[5].id | https://openalex.org/keywords/protocol |
| keywords[5].score | 0.5037958025932312 |
| keywords[5].display_name | Protocol (science) |
| keywords[6].id | https://openalex.org/keywords/effects-of-sleep-deprivation-on-cognitive-performance |
| keywords[6].score | 0.4369378089904785 |
| keywords[6].display_name | Effects of sleep deprivation on cognitive performance |
| keywords[7].id | https://openalex.org/keywords/randomized-controlled-trial |
| keywords[7].score | 0.4311670958995819 |
| keywords[7].display_name | Randomized controlled trial |
| keywords[8].id | https://openalex.org/keywords/cognitive-decline |
| keywords[8].score | 0.4291412830352783 |
| keywords[8].display_name | Cognitive decline |
| keywords[9].id | https://openalex.org/keywords/psychiatry |
| keywords[9].score | 0.39621007442474365 |
| keywords[9].display_name | Psychiatry |
| keywords[10].id | https://openalex.org/keywords/alcohol |
| keywords[10].score | 0.32747042179107666 |
| keywords[10].display_name | Alcohol |
| keywords[11].id | https://openalex.org/keywords/gerontology |
| keywords[11].score | 0.3262649178504944 |
| keywords[11].display_name | Gerontology |
| keywords[12].id | https://openalex.org/keywords/dementia |
| keywords[12].score | 0.19784143567085266 |
| keywords[12].display_name | Dementia |
| keywords[13].id | https://openalex.org/keywords/internal-medicine |
| keywords[13].score | 0.1821483075618744 |
| keywords[13].display_name | Internal medicine |
| keywords[14].id | https://openalex.org/keywords/family-medicine |
| keywords[14].score | 0.1548984944820404 |
| keywords[14].display_name | Family medicine |
| keywords[15].id | https://openalex.org/keywords/alternative-medicine |
| keywords[15].score | 0.14945968985557556 |
| keywords[15].display_name | Alternative medicine |
| keywords[16].id | https://openalex.org/keywords/disease |
| keywords[16].score | 0.10874050855636597 |
| keywords[16].display_name | Disease |
| language | en |
| locations[0].id | doi:10.2196/53684 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2739058702 |
| locations[0].source.issn | 1929-0748 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1929-0748 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | JMIR Research Protocols |
| locations[0].source.host_organization | https://openalex.org/P4310320608 |
| locations[0].source.host_organization_name | JMIR Publications |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320608 |
| locations[0].source.host_organization_lineage_names | JMIR Publications |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | JMIR Research Protocols |
| locations[0].landing_page_url | https://doi.org/10.2196/53684 |
| locations[1].id | pmid:38564243 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | JMIR research protocols |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/38564243 |
| locations[2].id | pmh:oai:doaj.org/article:a62cd6aab1b24d989ae0f2e8f146da19 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | JMIR Research Protocols, Vol 13, p e53684 (2024) |
| locations[2].landing_page_url | https://doaj.org/article/a62cd6aab1b24d989ae0f2e8f146da19 |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:11028398 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | JMIR Res Protoc |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11028398 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5101675767 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-7770-3754 |
| authorships[0].author.display_name | Robert L. Cook |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I33213144 |
| authorships[0].affiliations[0].raw_affiliation_string | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[0].institutions[0].id | https://openalex.org/I33213144 |
| authorships[0].institutions[0].ror | https://ror.org/02y3ad647 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I33213144 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | University of Florida |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Robert L Cook |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[1].author.id | https://openalex.org/A5004378388 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-1391-0607 |
| authorships[1].author.display_name | Veronica L. Richards |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I33213144 |
| authorships[1].affiliations[0].raw_affiliation_string | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I130769515 |
| authorships[1].affiliations[1].raw_affiliation_string | Edna Bennett Pierce Prevention Research Center, The Pennsylvania State University, University Park, PA, United States. |
| authorships[1].institutions[0].id | https://openalex.org/I130769515 |
| authorships[1].institutions[0].ror | https://ror.org/04p491231 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I130769515 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Pennsylvania State University |
| authorships[1].institutions[1].id | https://openalex.org/I33213144 |
| authorships[1].institutions[1].ror | https://ror.org/02y3ad647 |
| authorships[1].institutions[1].type | education |
| authorships[1].institutions[1].lineage | https://openalex.org/I33213144 |
| authorships[1].institutions[1].country_code | US |
| authorships[1].institutions[1].display_name | University of Florida |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Veronica L Richards |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Edna Bennett Pierce Prevention Research Center, The Pennsylvania State University, University Park, PA, United States., Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[2].author.id | https://openalex.org/A5048273534 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-8184-7187 |
| authorships[2].author.display_name | Joseph M. Gullett |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I33213144 |
| authorships[2].affiliations[0].raw_affiliation_string | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[2].institutions[0].id | https://openalex.org/I33213144 |
| authorships[2].institutions[0].ror | https://ror.org/02y3ad647 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I33213144 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | University of Florida |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Joseph M Gullett |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[3].author.id | https://openalex.org/A5046664020 |
| authorships[3].author.orcid | https://orcid.org/0009-0002-5770-1505 |
| authorships[3].author.display_name | Brenda Lerner |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I19700959 |
| authorships[3].affiliations[0].raw_affiliation_string | Florida International University, Miami, FL, United States. |
| authorships[3].institutions[0].id | https://openalex.org/I19700959 |
| authorships[3].institutions[0].ror | https://ror.org/02gz6gg07 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I19700959 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | Florida International University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Brenda D G Lerner |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Florida International University, Miami, FL, United States. |
| authorships[4].author.id | https://openalex.org/A5059429267 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-3861-5911 |
| authorships[4].author.display_name | Zhi Zhou |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I33213144 |
| authorships[4].affiliations[0].raw_affiliation_string | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[4].institutions[0].id | https://openalex.org/I33213144 |
| authorships[4].institutions[0].ror | https://ror.org/02y3ad647 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I33213144 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | University of Florida |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Zhi Zhou |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[5].author.id | https://openalex.org/A5068080913 |
| authorships[5].author.orcid | https://orcid.org/0000-0003-3885-5859 |
| authorships[5].author.display_name | Eric C. Porges |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I33213144, https://openalex.org/I4210159958 |
| authorships[5].affiliations[0].raw_affiliation_string | Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, United States. |
| authorships[5].institutions[0].id | https://openalex.org/I4210159958 |
| authorships[5].institutions[0].ror | https://ror.org/04s361q55 |
| authorships[5].institutions[0].type | company |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210159958 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Cognitive Research (United States) |
| authorships[5].institutions[1].id | https://openalex.org/I33213144 |
| authorships[5].institutions[1].ror | https://ror.org/02y3ad647 |
| authorships[5].institutions[1].type | education |
| authorships[5].institutions[1].lineage | https://openalex.org/I33213144 |
| authorships[5].institutions[1].country_code | US |
| authorships[5].institutions[1].display_name | University of Florida |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Eric C Porges |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, United States. |
| authorships[6].author.id | https://openalex.org/A5100322502 |
| authorships[6].author.orcid | https://orcid.org/0000-0001-7265-778X |
| authorships[6].author.display_name | Yan Wang |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I33213144 |
| authorships[6].affiliations[0].raw_affiliation_string | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[6].institutions[0].id | https://openalex.org/I33213144 |
| authorships[6].institutions[0].ror | https://ror.org/02y3ad647 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I33213144 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | University of Florida |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Yan Wang |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[7].author.id | https://openalex.org/A5038701619 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-6248-4149 |
| authorships[7].author.display_name | Christopher W. Kahler |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I27804330 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, United States. |
| authorships[7].institutions[0].id | https://openalex.org/I27804330 |
| authorships[7].institutions[0].ror | https://ror.org/05gq02987 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I27804330 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | Brown University |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Christopher W Kahler |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, United States. |
| authorships[8].author.id | https://openalex.org/A5041286994 |
| authorships[8].author.orcid | https://orcid.org/0000-0001-9634-8287 |
| authorships[8].author.display_name | Nancy P. Barnett |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I27804330 |
| authorships[8].affiliations[0].raw_affiliation_string | Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, United States. |
| authorships[8].institutions[0].id | https://openalex.org/I27804330 |
| authorships[8].institutions[0].ror | https://ror.org/05gq02987 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I27804330 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | Brown University |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Nancy P Barnett |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, United States. |
| authorships[9].author.id | https://openalex.org/A5100363804 |
| authorships[9].author.orcid | https://orcid.org/0000-0002-6224-1833 |
| authorships[9].author.display_name | Zhigang Li |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I33213144 |
| authorships[9].affiliations[0].raw_affiliation_string | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[9].institutions[0].id | https://openalex.org/I33213144 |
| authorships[9].institutions[0].ror | https://ror.org/02y3ad647 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I33213144 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | University of Florida |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Zhigang Li |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States. |
| authorships[10].author.id | https://openalex.org/A5024777848 |
| authorships[10].author.orcid | https://orcid.org/0000-0003-4451-8859 |
| authorships[10].author.display_name | Suresh Pallikkuth |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[10].affiliations[0].raw_affiliation_string | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[10].institutions[0].id | https://openalex.org/I145608581 |
| authorships[10].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | University of Miami |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Suresh Pallikkuth |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[11].author.id | https://openalex.org/A5022711470 |
| authorships[11].author.orcid | https://orcid.org/0000-0003-1416-3903 |
| authorships[11].author.display_name | Emmanuel Thomas |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[11].affiliations[0].raw_affiliation_string | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[11].institutions[0].id | https://openalex.org/I145608581 |
| authorships[11].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | University of Miami |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Emmanuel Thomas |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[12].author.id | https://openalex.org/A5015290437 |
| authorships[12].author.orcid | https://orcid.org/0000-0001-9477-3327 |
| authorships[12].author.display_name | Allan Rodríguez |
| authorships[12].countries | US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[12].affiliations[0].raw_affiliation_string | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[12].institutions[0].id | https://openalex.org/I145608581 |
| authorships[12].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[12].institutions[0].country_code | US |
| authorships[12].institutions[0].display_name | University of Miami |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Allan Rodriguez |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[13].author.id | https://openalex.org/A5025308612 |
| authorships[13].author.orcid | https://orcid.org/0000-0002-0792-1449 |
| authorships[13].author.display_name | Kendall Bryant |
| authorships[13].countries | US |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I4210121815 |
| authorships[13].affiliations[0].raw_affiliation_string | National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States. |
| authorships[13].institutions[0].id | https://openalex.org/I4210121815 |
| authorships[13].institutions[0].ror | https://ror.org/02jzrsm59 |
| authorships[13].institutions[0].type | facility |
| authorships[13].institutions[0].lineage | https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210121815 |
| authorships[13].institutions[0].country_code | US |
| authorships[13].institutions[0].display_name | National Institute on Alcohol Abuse and Alcoholism |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Kendall J Bryant |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States. |
| authorships[14].author.id | https://openalex.org/A5002649155 |
| authorships[14].author.orcid | https://orcid.org/0009-0005-9627-4843 |
| authorships[14].author.display_name | Smita Ghare |
| authorships[14].countries | US |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I142740786 |
| authorships[14].affiliations[0].raw_affiliation_string | Department of Medicine, University of Louisville, Louisville, KY, United States. |
| authorships[14].institutions[0].id | https://openalex.org/I142740786 |
| authorships[14].institutions[0].ror | https://ror.org/01ckdn478 |
| authorships[14].institutions[0].type | education |
| authorships[14].institutions[0].lineage | https://openalex.org/I142740786 |
| authorships[14].institutions[0].country_code | US |
| authorships[14].institutions[0].display_name | University of Louisville |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Smita Ghare |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Department of Medicine, University of Louisville, Louisville, KY, United States. |
| authorships[15].author.id | https://openalex.org/A5020633342 |
| authorships[15].author.orcid | https://orcid.org/0009-0008-7833-527X |
| authorships[15].author.display_name | Shirish Barve |
| authorships[15].countries | US |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I142740786 |
| authorships[15].affiliations[0].raw_affiliation_string | Department of Medicine, University of Louisville, Louisville, KY, United States. |
| authorships[15].institutions[0].id | https://openalex.org/I142740786 |
| authorships[15].institutions[0].ror | https://ror.org/01ckdn478 |
| authorships[15].institutions[0].type | education |
| authorships[15].institutions[0].lineage | https://openalex.org/I142740786 |
| authorships[15].institutions[0].country_code | US |
| authorships[15].institutions[0].display_name | University of Louisville |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Shirish Barve |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Department of Medicine, University of Louisville, Louisville, KY, United States. |
| authorships[16].author.id | https://openalex.org/A5021726068 |
| authorships[16].author.orcid | https://orcid.org/0000-0002-1205-5194 |
| authorships[16].author.display_name | Varan Govind |
| authorships[16].countries | US |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[16].affiliations[0].raw_affiliation_string | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[16].institutions[0].id | https://openalex.org/I145608581 |
| authorships[16].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[16].institutions[0].type | education |
| authorships[16].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[16].institutions[0].country_code | US |
| authorships[16].institutions[0].display_name | University of Miami |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Varan Govind |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States. |
| authorships[17].author.id | https://openalex.org/A5038663235 |
| authorships[17].author.orcid | https://orcid.org/0000-0001-6757-8753 |
| authorships[17].author.display_name | Jessy G. Dévieux |
| authorships[17].countries | US |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I19700959 |
| authorships[17].affiliations[0].raw_affiliation_string | Florida International University, Miami, FL, United States. |
| authorships[17].institutions[0].id | https://openalex.org/I19700959 |
| authorships[17].institutions[0].ror | https://ror.org/02gz6gg07 |
| authorships[17].institutions[0].type | education |
| authorships[17].institutions[0].lineage | https://openalex.org/I19700959 |
| authorships[17].institutions[0].country_code | US |
| authorships[17].institutions[0].display_name | Florida International University |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | Jessy G Dévieux |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Florida International University, Miami, FL, United States. |
| authorships[18].author.id | https://openalex.org/A5035290107 |
| authorships[18].author.orcid | https://orcid.org/0000-0002-8863-8847 |
| authorships[18].author.display_name | Ronald A. Cohen |
| authorships[18].countries | US |
| authorships[18].affiliations[0].institution_ids | https://openalex.org/I33213144, https://openalex.org/I4210159958 |
| authorships[18].affiliations[0].raw_affiliation_string | Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, United States. |
| authorships[18].institutions[0].id | https://openalex.org/I4210159958 |
| authorships[18].institutions[0].ror | https://ror.org/04s361q55 |
| authorships[18].institutions[0].type | company |
| authorships[18].institutions[0].lineage | https://openalex.org/I4210159958 |
| authorships[18].institutions[0].country_code | US |
| authorships[18].institutions[0].display_name | Cognitive Research (United States) |
| authorships[18].institutions[1].id | https://openalex.org/I33213144 |
| authorships[18].institutions[1].ror | https://ror.org/02y3ad647 |
| authorships[18].institutions[1].type | education |
| authorships[18].institutions[1].lineage | https://openalex.org/I33213144 |
| authorships[18].institutions[1].country_code | US |
| authorships[18].institutions[1].display_name | University of Florida |
| authorships[18].author_position | last |
| authorships[18].raw_author_name | Ronald A Cohen |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, United States. |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.2196/53684 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-25T14:43:58.451035 |
| primary_topic.id | https://openalex.org/T13966 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9965000152587891 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2712 |
| primary_topic.subfield.display_name | Endocrinology, Diabetes and Metabolism |
| primary_topic.display_name | Neurological and metabolic disorders |
| related_works | https://openalex.org/W4211097364, https://openalex.org/W2333909762, https://openalex.org/W4248817419, https://openalex.org/W2412763010, https://openalex.org/W2066862511, https://openalex.org/W1167265671, https://openalex.org/W4401033529, https://openalex.org/W2409544820, https://openalex.org/W2150916106, https://openalex.org/W4390192487 |
| cited_by_count | 0 |
| locations_count | 4 |
| best_oa_location.id | doi:10.2196/53684 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2739058702 |
| best_oa_location.source.issn | 1929-0748 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1929-0748 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | JMIR Research Protocols |
| best_oa_location.source.host_organization | https://openalex.org/P4310320608 |
| best_oa_location.source.host_organization_name | JMIR Publications |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320608 |
| best_oa_location.source.host_organization_lineage_names | JMIR Publications |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | JMIR Research Protocols |
| best_oa_location.landing_page_url | https://doi.org/10.2196/53684 |
| primary_location.id | doi:10.2196/53684 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2739058702 |
| primary_location.source.issn | 1929-0748 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1929-0748 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | JMIR Research Protocols |
| primary_location.source.host_organization | https://openalex.org/P4310320608 |
| primary_location.source.host_organization_name | JMIR Publications |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320608 |
| primary_location.source.host_organization_lineage_names | JMIR Publications |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | JMIR Research Protocols |
| primary_location.landing_page_url | https://doi.org/10.2196/53684 |
| publication_date | 2023-11-09 |
| publication_year | 2023 |
| referenced_works | https://openalex.org/W2521342226, https://openalex.org/W2770823248, https://openalex.org/W2460166417, https://openalex.org/W2153858533, https://openalex.org/W2251454683, https://openalex.org/W2899221401, https://openalex.org/W2516366771, https://openalex.org/W2271639429, https://openalex.org/W3097638062, https://openalex.org/W2581389537, https://openalex.org/W2013595983, https://openalex.org/W2040002999, https://openalex.org/W3137127954, https://openalex.org/W2728731909, https://openalex.org/W2008320988, https://openalex.org/W1985451137, https://openalex.org/W2790172508, https://openalex.org/W2043880809, https://openalex.org/W2165758561, https://openalex.org/W2011410195, https://openalex.org/W1475474724, https://openalex.org/W2172151487, https://openalex.org/W2059251460, https://openalex.org/W1489249390, https://openalex.org/W2151487996, https://openalex.org/W1544644153, https://openalex.org/W2043705607, https://openalex.org/W2132322340, https://openalex.org/W2375701190, https://openalex.org/W2269592175, https://openalex.org/W2320909684, https://openalex.org/W2060468894, https://openalex.org/W2098658501, https://openalex.org/W2028013615, https://openalex.org/W2092926615, https://openalex.org/W1858508207, https://openalex.org/W4296295377, https://openalex.org/W2120357670, https://openalex.org/W2044726369, https://openalex.org/W4296086374, https://openalex.org/W2035258898, https://openalex.org/W2134551595, https://openalex.org/W2169232412, https://openalex.org/W2784551971, https://openalex.org/W2116823839, https://openalex.org/W2166311155, https://openalex.org/W2058363360, https://openalex.org/W2580488783, https://openalex.org/W2919596485, https://openalex.org/W2167883938, https://openalex.org/W3013503722, https://openalex.org/W2110065044, https://openalex.org/W2005322823, https://openalex.org/W228126680, https://openalex.org/W2140205353, https://openalex.org/W2000900774, https://openalex.org/W2370820144 |
| referenced_works_count | 57 |
| abstract_inverted_index.1 | 196 |
| abstract_inverted_index.a | 81, 141, 163 |
| abstract_inverted_index.14 | 126 |
| abstract_inverted_index.21 | 120 |
| abstract_inverted_index.30 | 159, 191 |
| abstract_inverted_index.43 | 240 |
| abstract_inverted_index.45 | 109 |
| abstract_inverted_index.50 | 235 |
| abstract_inverted_index.56 | 216 |
| abstract_inverted_index.57 | 203 |
| abstract_inverted_index.90 | 193 |
| abstract_inverted_index.SD | 218 |
| abstract_inverted_index.We | 201 |
| abstract_inverted_index.an | 90, 146 |
| abstract_inverted_index.as | 287 |
| abstract_inverted_index.at | 134, 157, 189 |
| abstract_inverted_index.be | 54, 313 |
| abstract_inverted_index.by | 95, 162 |
| abstract_inverted_index.if | 106 |
| abstract_inverted_index.in | 16, 58, 68, 71, 85, 269, 277, 305 |
| abstract_inverted_index.is | 28, 36 |
| abstract_inverted_index.of | 34, 51, 61, 98, 111, 119, 137, 149, 233, 257 |
| abstract_inverted_index.or | 32, 49, 113, 121, 125, 127, 174 |
| abstract_inverted_index.to | 22, 45, 253, 266 |
| abstract_inverted_index.4.6 | 219 |
| abstract_inverted_index.HIV | 5, 281, 286 |
| abstract_inverted_index.The | 39, 77, 244 |
| abstract_inverted_index.age | 112, 215 |
| abstract_inverted_index.all | 87 |
| abstract_inverted_index.and | 4, 13, 25, 63, 66, 100, 131, 181, 184, 195, 227, 239, 250, 272, 293 |
| abstract_inverted_index.are | 7, 300, 304 |
| abstract_inverted_index.due | 252 |
| abstract_inverted_index.for | 153, 156, 295, 315 |
| abstract_inverted_index.had | 115 |
| abstract_inverted_index.not | 133 |
| abstract_inverted_index.the | 20, 210, 241, 254, 262 |
| abstract_inverted_index.was | 43, 80, 261 |
| abstract_inverted_index.who | 208 |
| abstract_inverted_index.58%, | 228 |
| abstract_inverted_index.63%, | 221 |
| abstract_inverted_index.77%, | 224 |
| abstract_inverted_index.Both | 1 |
| abstract_inverted_index.HIV) | 232 |
| abstract_inverted_index.This | 260 |
| abstract_inverted_index.data | 311 |
| abstract_inverted_index.days | 160 |
| abstract_inverted_index.high | 135 |
| abstract_inverted_index.more | 122, 128 |
| abstract_inverted_index.n=33 | 229 |
| abstract_inverted_index.n=36 | 222 |
| abstract_inverted_index.n=44 | 225 |
| abstract_inverted_index.not. | 175 |
| abstract_inverted_index.risk | 136 |
| abstract_inverted_index.they | 107 |
| abstract_inverted_index.were | 104, 108, 132, 187, 248 |
| abstract_inverted_index.whom | 234 |
| abstract_inverted_index.will | 312 |
| abstract_inverted_index.with | 9, 30, 56, 73, 205, 231, 280, 283 |
| abstract_inverted_index.year | 197 |
| abstract_inverted_index.(mean | 214 |
| abstract_inverted_index.(men) | 124 |
| abstract_inverted_index.After | 140, 167 |
| abstract_inverted_index.Study | 176, 289 |
| abstract_inverted_index.Trial | 317 |
| abstract_inverted_index.after | 198, 274, 307 |
| abstract_inverted_index.brain | 24, 64, 270 |
| abstract_inverted_index.brief | 164 |
| abstract_inverted_index.could | 170 |
| abstract_inverted_index.days) | 155 |
| abstract_inverted_index.days, | 192, 194 |
| abstract_inverted_index.first | 263 |
| abstract_inverted_index.heavy | 74, 206 |
| abstract_inverted_index.least | 158 |
| abstract_inverted_index.male, | 223 |
| abstract_inverted_index.older | 17 |
| abstract_inverted_index.stool | 185 |
| abstract_inverted_index.study | 42, 78, 246, 264, 297, 310 |
| abstract_inverted_index.this, | 168 |
| abstract_inverted_index.which | 23, 86, 308 |
| abstract_inverted_index.worse | 10 |
| abstract_inverted_index.would | 53 |
| abstract_inverted_index.years | 110 |
| abstract_inverted_index.(money | 152 |
| abstract_inverted_index.30-Day | 40 |
| abstract_inverted_index.30-day | 237 |
| abstract_inverted_index.90-day | 242 |
| abstract_inverted_index.Black, | 226 |
| abstract_inverted_index.Report | 324 |
| abstract_inverted_index.adults | 72 |
| abstract_inverted_index.assess | 267 |
| abstract_inverted_index.blood, | 182 |
| abstract_inverted_index.brain, | 11 |
| abstract_inverted_index.design | 79, 290, 298 |
| abstract_inverted_index.drinks | 123, 129 |
| abstract_inverted_index.either | 171 |
| abstract_inverted_index.extent | 21 |
| abstract_inverted_index.future | 296 |
| abstract_inverted_index.older, | 114 |
| abstract_inverted_index.people | 230, 279, 284 |
| abstract_inverted_index.resume | 172 |
| abstract_inverted_index.trial, | 84 |
| abstract_inverted_index.urine, | 183 |
| abstract_inverted_index.weekly | 116 |
| abstract_inverted_index.years, | 217 |
| abstract_inverted_index.years; | 220 |
| abstract_inverted_index.(IRRID) | 326 |
| abstract_inverted_index.Methods | 76 |
| abstract_inverted_index.Persons | 103 |
| abstract_inverted_index.Planned | 302 |
| abstract_inverted_index.Results | 200 |
| abstract_inverted_index.adults. | 18 |
| abstract_inverted_index.alcohol | 2, 91, 117, 138, 275 |
| abstract_inverted_index.changes | 268 |
| abstract_inverted_index.lessons | 294 |
| abstract_inverted_index.persons | 204 |
| abstract_inverted_index.planned | 245 |
| abstract_inverted_index.samples | 186 |
| abstract_inverted_index.seeking | 265 |
| abstract_inverted_index.whether | 47 |
| abstract_inverted_index.without | 285 |
| abstract_inverted_index.(women), | 130 |
| abstract_inverted_index.COVID-19 | 255 |
| abstract_inverted_index.However, | 19 |
| abstract_inverted_index.analyses | 303 |
| abstract_inverted_index.baseline | 142 |
| abstract_inverted_index.clinical | 14, 101 |
| abstract_inverted_index.designed | 44 |
| abstract_inverted_index.drinking | 35, 52, 173, 207 |
| abstract_inverted_index.eligible | 105 |
| abstract_inverted_index.enrolled | 202 |
| abstract_inverted_index.followed | 94, 161 |
| abstract_inverted_index.modified | 251 |
| abstract_inverted_index.outcomes | 15, 70 |
| abstract_inverted_index.pandemic | 256 |
| abstract_inverted_index.protocol | 213 |
| abstract_inverted_index.received | 89, 145 |
| abstract_inverted_index.repeated | 96 |
| abstract_inverted_index.sharing. | 316 |
| abstract_inverted_index.systemic | 62 |
| abstract_inverted_index.together | 282 |
| abstract_inverted_index.unknown. | 37 |
| abstract_inverted_index.Challenge | 41 |
| abstract_inverted_index.Objective | 38 |
| abstract_inverted_index.available | 314 |
| abstract_inverted_index.baseline, | 190 |
| abstract_inverted_index.cessation | 33, 50 |
| abstract_inverted_index.cognition | 273 |
| abstract_inverted_index.cognitive | 26 |
| abstract_inverted_index.collected | 188 |
| abstract_inverted_index.completed | 236 |
| abstract_inverted_index.controls. | 288 |
| abstract_inverted_index.determine | 46 |
| abstract_inverted_index.drinking. | 75 |
| abstract_inverted_index.follow-up | 238 |
| abstract_inverted_index.infection | 6 |
| abstract_inverted_index.initiated | 209 |
| abstract_inverted_index.outcomes. | 102 |
| abstract_inverted_index.progress, | 306 |
| abstract_inverted_index.reduction | 31, 48, 60, 92 |
| abstract_inverted_index.2020-2021. | 258 |
| abstract_inverted_index.Background | 0 |
| abstract_inverted_index.Identifier | 325 |
| abstract_inverted_index.Registered | 323 |
| abstract_inverted_index.associated | 8, 55 |
| abstract_inverted_index.behavioral | 99 |
| abstract_inverted_index.cognition, | 59 |
| abstract_inverted_index.cognitive, | 12 |
| abstract_inverted_index.consisting | 148 |
| abstract_inverted_index.discussed. | 301 |
| abstract_inverted_index.follow-up. | 243 |
| abstract_inverted_index.interview. | 166 |
| abstract_inverted_index.management | 151, 212 |
| abstract_inverted_index.procedures | 247 |
| abstract_inverted_index.reversible | 29 |
| abstract_inverted_index.strengths, | 291 |
| abstract_inverted_index.Conclusions | 259 |
| abstract_inverted_index.HIV-related | 69 |
| abstract_inverted_index.assessment, | 143 |
| abstract_inverted_index.assessments | 97 |
| abstract_inverted_index.consumption | 3, 118 |
| abstract_inverted_index.contingency | 150, 211 |
| abstract_inverted_index.dysfunction | 27 |
| abstract_inverted_index.enrollment. | 199 |
| abstract_inverted_index.improvement | 67 |
| abstract_inverted_index.interrupted | 249 |
| abstract_inverted_index.mechanistic | 82 |
| abstract_inverted_index.nondrinking | 154 |
| abstract_inverted_index.withdrawal. | 139 |
| abstract_inverted_index.NCT03353701; | 320 |
| abstract_inverted_index.Registration | 318 |
| abstract_inverted_index.assessments, | 179 |
| abstract_inverted_index.deidentified | 309 |
| abstract_inverted_index.experimental | 83 |
| abstract_inverted_index.improvements | 57 |
| abstract_inverted_index.intervention | 93, 147, 276 |
| abstract_inverted_index.limitations, | 292 |
| abstract_inverted_index.motivational | 165 |
| abstract_inverted_index.participants | 88, 144, 169 |
| abstract_inverted_index.International | 322 |
| abstract_inverted_index.inflammation, | 65 |
| abstract_inverted_index.neuroimaging, | 180 |
| abstract_inverted_index.(neuroimaging) | 271 |
| abstract_inverted_index.considerations | 299 |
| abstract_inverted_index.neurocognitive | 178 |
| abstract_inverted_index.questionnaires, | 177 |
| abstract_inverted_index.ClinicalTrials.gov | 319 |
| abstract_inverted_index.DERR1-10.2196/53684 | 327 |
| abstract_inverted_index.nontreatment-seeking | 278 |
| abstract_inverted_index.https://clinicaltrials.gov/study/NCT03353701 | 321 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 19 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.6800000071525574 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.32452226 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |