Exploring the relationship between HCMV serostatus and outcomes in COVID-19 sepsis Article Swipe
Dominik Ziehe
,
Alexander Wolf
,
Tim Rahmel
,
Hartmuth Nowak
,
Helge Haberl
,
Lars Bergmann
,
Katharina Rump
,
Birte Dyck
,
Lars Palmowski
,
Britta Marko
,
Andrea Witowski
,
Katrin Willemsen
,
Stephanie Pfaender
,
Martin Eisenacher
,
Moritz Anft
,
Nina Babel
,
Thilo Bracht
,
Barbara Sitek
,
Malte Bayer
,
Alexander Zarbock
,
Thilo von Groote
,
Christian Putensen
,
Stefan Ehrentraut
,
Christina Weisheit
,
Michael Adamzik
,
Matthias Unterberg
,
Björn Koos
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3389/fimmu.2024.1386586
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3389/fimmu.2024.1386586
Background Sepsis, a life-threatening condition caused by the dysregulated host response to infection, is a major global health concern. Understanding the impact of viral or bacterial pathogens in sepsis is crucial for improving patient outcomes. This study aimed to investigate the human cytomegalovirus (HCMV) seropositivity as a risk factor for development of sepsis in patients with COVID-19. Methods A multicenter observational study enrolled 95 intensive care patients with COVID-19-induced sepsis and 80 post-surgery individuals as controls. HCMV serostatus was determined using an ELISA test. Comprehensive clinical data, including demographics, comorbidities, and 30-day mortality, were collected. Statistical analyses evaluated the association between HCMV seropositivity and COVID-19 induced sepsis. Results The prevalence of HCMV seropositivity did not significantly differ between COVID-19-induced sepsis patients (78%) and controls (71%, p = 0.382) in the entire cohort. However, among patients aged ≤60 years, HCMV seropositivity was significantly higher in COVID-19 sepsis patients compared to controls (86% vs 61%, respectively; p = 0.030). Nevertheless, HCMV serostatus did not affect 30-day survival. Discussion These findings confirm the association between HCMV seropositivity and COVID-19 sepsis in non-geriatric patients. However, the lack of an independent effect on 30-day survival can be explained by the cross-reactivity of HCMV specific CD8 + T-cells towards SARS-CoV-2 peptides, which might confer some protection to HCMV seropositive patients. The inclusion of a post-surgery control group strengthens the generalizability of the findings. Further research is needed to elucidate the underlying mechanisms of this association, explore different patient populations, and identify interventions for optimizing patient management. Conclusion This study validates the association between HCMV seropositivity and severe COVID-19-induced sepsis in non-geriatric patients, contributing to the growing body of evidence on viral pathogens in sepsis. Although HCMV serostatus did not independently influence 30-day survival, future investigations should focus on unraveling the intricate interplay between HCMV, immune responses, and COVID-19. These insights will aid in risk stratification and the development of targeted interventions for viral sepsis.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fimmu.2024.1386586
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1386586/pdf
- OA Status
- gold
- Cited By
- 2
- References
- 43
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4396743734
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4396743734Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3389/fimmu.2024.1386586Digital Object Identifier
- Title
-
Exploring the relationship between HCMV serostatus and outcomes in COVID-19 sepsisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-05-08Full publication date if available
- Authors
-
Dominik Ziehe, Alexander Wolf, Tim Rahmel, Hartmuth Nowak, Helge Haberl, Lars Bergmann, Katharina Rump, Birte Dyck, Lars Palmowski, Britta Marko, Andrea Witowski, Katrin Willemsen, Stephanie Pfaender, Martin Eisenacher, Moritz Anft, Nina Babel, Thilo Bracht, Barbara Sitek, Malte Bayer, Alexander Zarbock, Thilo von Groote, Christian Putensen, Stefan Ehrentraut, Christina Weisheit, Michael Adamzik, Matthias Unterberg, Björn KoosList of authors in order
- Landing page
-
https://doi.org/10.3389/fimmu.2024.1386586Publisher landing page
- PDF URL
-
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1386586/pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1386586/pdfDirect OA link when available
- Concepts
-
Serostatus, Medicine, Sepsis, Human cytomegalovirus, Internal medicine, Immunology, Cohort study, Virus, Viral loadTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
2Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 1Per-year citation counts (last 5 years)
- References (count)
-
43Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4396743734 |
|---|---|
| doi | https://doi.org/10.3389/fimmu.2024.1386586 |
| ids.doi | https://doi.org/10.3389/fimmu.2024.1386586 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/38779663 |
| ids.openalex | https://openalex.org/W4396743734 |
| fwci | 1.84310621 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000276 |
| mesh[1].descriptor_ui | D000086382 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | immunology |
| mesh[1].descriptor_name | COVID-19 |
| mesh[2].qualifier_ui | Q000401 |
| mesh[2].descriptor_ui | D000086382 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | mortality |
| mesh[2].descriptor_name | COVID-19 |
| mesh[3].qualifier_ui | Q000453 |
| mesh[3].descriptor_ui | D000086382 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | epidemiology |
| mesh[3].descriptor_name | COVID-19 |
| mesh[4].qualifier_ui | Q000150 |
| mesh[4].descriptor_ui | D000086382 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | complications |
| mesh[4].descriptor_name | COVID-19 |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D008297 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Male |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D005260 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Female |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D008875 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Middle Aged |
| mesh[8].qualifier_ui | Q000276 |
| mesh[8].descriptor_ui | D018805 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | immunology |
| mesh[8].descriptor_name | Sepsis |
| mesh[9].qualifier_ui | Q000453 |
| mesh[9].descriptor_ui | D018805 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | epidemiology |
| mesh[9].descriptor_name | Sepsis |
| mesh[10].qualifier_ui | Q000401 |
| mesh[10].descriptor_ui | D018805 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | mortality |
| mesh[10].descriptor_name | Sepsis |
| mesh[11].qualifier_ui | Q000276 |
| mesh[11].descriptor_ui | D003587 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | immunology |
| mesh[11].descriptor_name | Cytomegalovirus |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D000368 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Aged |
| mesh[13].qualifier_ui | Q000276 |
| mesh[13].descriptor_ui | D003586 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | immunology |
| mesh[13].descriptor_name | Cytomegalovirus Infections |
| mesh[14].qualifier_ui | Q000453 |
| mesh[14].descriptor_ui | D003586 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | epidemiology |
| mesh[14].descriptor_name | Cytomegalovirus Infections |
| mesh[15].qualifier_ui | Q000401 |
| mesh[15].descriptor_ui | D003586 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | mortality |
| mesh[15].descriptor_name | Cytomegalovirus Infections |
| mesh[16].qualifier_ui | Q000150 |
| mesh[16].descriptor_ui | D003586 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | complications |
| mesh[16].descriptor_name | Cytomegalovirus Infections |
| mesh[17].qualifier_ui | Q000276 |
| mesh[17].descriptor_ui | D000086402 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | immunology |
| mesh[17].descriptor_name | SARS-CoV-2 |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D012307 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Risk Factors |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D000328 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Adult |
| mesh[20].qualifier_ui | Q000097 |
| mesh[20].descriptor_ui | D000914 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | blood |
| mesh[20].descriptor_name | Antibodies, Viral |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D006801 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Humans |
| mesh[22].qualifier_ui | Q000276 |
| mesh[22].descriptor_ui | D000086382 |
| mesh[22].is_major_topic | True |
| mesh[22].qualifier_name | immunology |
| mesh[22].descriptor_name | COVID-19 |
| mesh[23].qualifier_ui | Q000401 |
| mesh[23].descriptor_ui | D000086382 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | mortality |
| mesh[23].descriptor_name | COVID-19 |
| mesh[24].qualifier_ui | Q000453 |
| mesh[24].descriptor_ui | D000086382 |
| mesh[24].is_major_topic | True |
| mesh[24].qualifier_name | epidemiology |
| mesh[24].descriptor_name | COVID-19 |
| mesh[25].qualifier_ui | Q000150 |
| mesh[25].descriptor_ui | D000086382 |
| mesh[25].is_major_topic | True |
| mesh[25].qualifier_name | complications |
| mesh[25].descriptor_name | COVID-19 |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D008297 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Male |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D005260 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Female |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D008875 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Middle Aged |
| mesh[29].qualifier_ui | Q000276 |
| mesh[29].descriptor_ui | D018805 |
| mesh[29].is_major_topic | True |
| mesh[29].qualifier_name | immunology |
| mesh[29].descriptor_name | Sepsis |
| mesh[30].qualifier_ui | Q000453 |
| mesh[30].descriptor_ui | D018805 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | epidemiology |
| mesh[30].descriptor_name | Sepsis |
| mesh[31].qualifier_ui | Q000401 |
| mesh[31].descriptor_ui | D018805 |
| mesh[31].is_major_topic | True |
| mesh[31].qualifier_name | mortality |
| mesh[31].descriptor_name | Sepsis |
| mesh[32].qualifier_ui | Q000276 |
| mesh[32].descriptor_ui | D003587 |
| mesh[32].is_major_topic | True |
| mesh[32].qualifier_name | immunology |
| mesh[32].descriptor_name | Cytomegalovirus |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D000368 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Aged |
| mesh[34].qualifier_ui | Q000276 |
| mesh[34].descriptor_ui | D003586 |
| mesh[34].is_major_topic | True |
| mesh[34].qualifier_name | immunology |
| mesh[34].descriptor_name | Cytomegalovirus Infections |
| mesh[35].qualifier_ui | Q000453 |
| mesh[35].descriptor_ui | D003586 |
| mesh[35].is_major_topic | True |
| mesh[35].qualifier_name | epidemiology |
| mesh[35].descriptor_name | Cytomegalovirus Infections |
| mesh[36].qualifier_ui | Q000401 |
| mesh[36].descriptor_ui | D003586 |
| mesh[36].is_major_topic | True |
| mesh[36].qualifier_name | mortality |
| mesh[36].descriptor_name | Cytomegalovirus Infections |
| mesh[37].qualifier_ui | Q000150 |
| mesh[37].descriptor_ui | D003586 |
| mesh[37].is_major_topic | True |
| mesh[37].qualifier_name | complications |
| mesh[37].descriptor_name | Cytomegalovirus Infections |
| mesh[38].qualifier_ui | Q000276 |
| mesh[38].descriptor_ui | D000086402 |
| mesh[38].is_major_topic | True |
| mesh[38].qualifier_name | immunology |
| mesh[38].descriptor_name | SARS-CoV-2 |
| mesh[39].qualifier_ui | |
| mesh[39].descriptor_ui | D012307 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | |
| mesh[39].descriptor_name | Risk Factors |
| mesh[40].qualifier_ui | |
| mesh[40].descriptor_ui | D000328 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | |
| mesh[40].descriptor_name | Adult |
| mesh[41].qualifier_ui | Q000097 |
| mesh[41].descriptor_ui | D000914 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | blood |
| mesh[41].descriptor_name | Antibodies, Viral |
| mesh[42].qualifier_ui | |
| mesh[42].descriptor_ui | D006801 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | |
| mesh[42].descriptor_name | Humans |
| mesh[43].qualifier_ui | Q000276 |
| mesh[43].descriptor_ui | D000086382 |
| mesh[43].is_major_topic | True |
| mesh[43].qualifier_name | immunology |
| mesh[43].descriptor_name | COVID-19 |
| mesh[44].qualifier_ui | Q000401 |
| mesh[44].descriptor_ui | D000086382 |
| mesh[44].is_major_topic | True |
| mesh[44].qualifier_name | mortality |
| mesh[44].descriptor_name | COVID-19 |
| mesh[45].qualifier_ui | Q000453 |
| mesh[45].descriptor_ui | D000086382 |
| mesh[45].is_major_topic | True |
| mesh[45].qualifier_name | epidemiology |
| mesh[45].descriptor_name | COVID-19 |
| mesh[46].qualifier_ui | Q000150 |
| mesh[46].descriptor_ui | D000086382 |
| mesh[46].is_major_topic | True |
| mesh[46].qualifier_name | complications |
| mesh[46].descriptor_name | COVID-19 |
| mesh[47].qualifier_ui | |
| mesh[47].descriptor_ui | D008297 |
| mesh[47].is_major_topic | False |
| mesh[47].qualifier_name | |
| mesh[47].descriptor_name | Male |
| mesh[48].qualifier_ui | |
| mesh[48].descriptor_ui | D005260 |
| mesh[48].is_major_topic | False |
| mesh[48].qualifier_name | |
| mesh[48].descriptor_name | Female |
| mesh[49].qualifier_ui | |
| mesh[49].descriptor_ui | D008875 |
| mesh[49].is_major_topic | False |
| mesh[49].qualifier_name | |
| mesh[49].descriptor_name | Middle Aged |
| type | article |
| title | Exploring the relationship between HCMV serostatus and outcomes in COVID-19 sepsis |
| biblio.issue | |
| biblio.volume | 15 |
| biblio.last_page | 1386586 |
| biblio.first_page | 1386586 |
| grants[0].funder | https://openalex.org/F4320335322 |
| grants[0].award_id | |
| grants[0].funder_display_name | European Regional Development Fund |
| topics[0].id | https://openalex.org/T10218 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9984999895095825 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2713 |
| topics[0].subfield.display_name | Epidemiology |
| topics[0].display_name | Sepsis Diagnosis and Treatment |
| topics[1].id | https://openalex.org/T10981 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9983999729156494 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2713 |
| topics[1].subfield.display_name | Epidemiology |
| topics[1].display_name | Cytomegalovirus and herpesvirus research |
| topics[2].id | https://openalex.org/T10041 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9976999759674072 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2725 |
| topics[2].subfield.display_name | Infectious Diseases |
| topics[2].display_name | COVID-19 Clinical Research Studies |
| funders[0].id | https://openalex.org/F4320335322 |
| funders[0].ror | https://ror.org/00k4n6c32 |
| funders[0].display_name | European Regional Development Fund |
| is_xpac | False |
| apc_list.value | 2950 |
| apc_list.currency | USD |
| apc_list.value_usd | 2950 |
| apc_paid.value | 2950 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 2950 |
| concepts[0].id | https://openalex.org/C2776535787 |
| concepts[0].level | 4 |
| concepts[0].score | 0.9522464275360107 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1084257 |
| concepts[0].display_name | Serostatus |
| concepts[1].id | https://openalex.org/C71924100 |
| concepts[1].level | 0 |
| concepts[1].score | 0.8397455215454102 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[1].display_name | Medicine |
| concepts[2].id | https://openalex.org/C2778384902 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6794151067733765 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q183134 |
| concepts[2].display_name | Sepsis |
| concepts[3].id | https://openalex.org/C2779820661 |
| concepts[3].level | 3 |
| concepts[3].score | 0.588304877281189 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q6929 |
| concepts[3].display_name | Human cytomegalovirus |
| concepts[4].id | https://openalex.org/C126322002 |
| concepts[4].level | 1 |
| concepts[4].score | 0.44610467553138733 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[4].display_name | Internal medicine |
| concepts[5].id | https://openalex.org/C203014093 |
| concepts[5].level | 1 |
| concepts[5].score | 0.43712085485458374 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q101929 |
| concepts[5].display_name | Immunology |
| concepts[6].id | https://openalex.org/C201903717 |
| concepts[6].level | 2 |
| concepts[6].score | 0.4326667785644531 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q1778788 |
| concepts[6].display_name | Cohort study |
| concepts[7].id | https://openalex.org/C2522874641 |
| concepts[7].level | 2 |
| concepts[7].score | 0.14660218358039856 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q808 |
| concepts[7].display_name | Virus |
| concepts[8].id | https://openalex.org/C142462285 |
| concepts[8].level | 3 |
| concepts[8].score | 0.14194750785827637 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q2528140 |
| concepts[8].display_name | Viral load |
| keywords[0].id | https://openalex.org/keywords/serostatus |
| keywords[0].score | 0.9522464275360107 |
| keywords[0].display_name | Serostatus |
| keywords[1].id | https://openalex.org/keywords/medicine |
| keywords[1].score | 0.8397455215454102 |
| keywords[1].display_name | Medicine |
| keywords[2].id | https://openalex.org/keywords/sepsis |
| keywords[2].score | 0.6794151067733765 |
| keywords[2].display_name | Sepsis |
| keywords[3].id | https://openalex.org/keywords/human-cytomegalovirus |
| keywords[3].score | 0.588304877281189 |
| keywords[3].display_name | Human cytomegalovirus |
| keywords[4].id | https://openalex.org/keywords/internal-medicine |
| keywords[4].score | 0.44610467553138733 |
| keywords[4].display_name | Internal medicine |
| keywords[5].id | https://openalex.org/keywords/immunology |
| keywords[5].score | 0.43712085485458374 |
| keywords[5].display_name | Immunology |
| keywords[6].id | https://openalex.org/keywords/cohort-study |
| keywords[6].score | 0.4326667785644531 |
| keywords[6].display_name | Cohort study |
| keywords[7].id | https://openalex.org/keywords/virus |
| keywords[7].score | 0.14660218358039856 |
| keywords[7].display_name | Virus |
| keywords[8].id | https://openalex.org/keywords/viral-load |
| keywords[8].score | 0.14194750785827637 |
| keywords[8].display_name | Viral load |
| language | en |
| locations[0].id | doi:10.3389/fimmu.2024.1386586 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2595292759 |
| locations[0].source.issn | 1664-3224 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1664-3224 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Frontiers in Immunology |
| locations[0].source.host_organization | https://openalex.org/P4310320527 |
| locations[0].source.host_organization_name | Frontiers Media |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320527 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1386586/pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Frontiers in Immunology |
| locations[0].landing_page_url | https://doi.org/10.3389/fimmu.2024.1386586 |
| locations[1].id | pmid:38779663 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Frontiers in immunology |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/38779663 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:11109369 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Front Immunol |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11109369 |
| locations[3].id | pmh:oai:doaj.org/article:bf6524ce840e4ab5b98ee142f17dbc9e |
| locations[3].is_oa | False |
| locations[3].source.id | https://openalex.org/S4306401280 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[3].source.host_organization | |
| locations[3].source.host_organization_name | |
| locations[3].source.host_organization_lineage | |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | article |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Frontiers in Immunology, Vol 15 (2024) |
| locations[3].landing_page_url | https://doaj.org/article/bf6524ce840e4ab5b98ee142f17dbc9e |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5085555876 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Dominik Ziehe |
| authorships[0].countries | DE |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[0].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[0].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[0].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[0].institutions[0].country_code | DE |
| authorships[0].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Dominik Ziehe |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[1].author.id | https://openalex.org/A5070180710 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-8875-586X |
| authorships[1].author.display_name | Alexander Wolf |
| authorships[1].countries | DE |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[1].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[1].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[1].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[1].institutions[0].country_code | DE |
| authorships[1].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Alexander Wolf |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[2].author.id | https://openalex.org/A5021025682 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-7039-6288 |
| authorships[2].author.display_name | Tim Rahmel |
| authorships[2].countries | DE |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[2].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[2].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[2].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[2].institutions[0].country_code | DE |
| authorships[2].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Tim Rahmel |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[3].author.id | https://openalex.org/A5078496632 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-6509-1463 |
| authorships[3].author.display_name | Hartmuth Nowak |
| authorships[3].countries | DE |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[3].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[3].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[3].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[3].institutions[0].country_code | DE |
| authorships[3].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Hartmuth Nowak |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[4].author.id | https://openalex.org/A5036670724 |
| authorships[4].author.orcid | |
| authorships[4].author.display_name | Helge Haberl |
| authorships[4].countries | DE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[4].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[4].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[4].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[4].institutions[0].country_code | DE |
| authorships[4].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Helge Haberl |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[5].author.id | https://openalex.org/A5047335832 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-8603-8549 |
| authorships[5].author.display_name | Lars Bergmann |
| authorships[5].countries | DE |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[5].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[5].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[5].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[5].institutions[0].country_code | DE |
| authorships[5].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Lars Bergmann |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[6].author.id | https://openalex.org/A5052760825 |
| authorships[6].author.orcid | https://orcid.org/0000-0003-2220-519X |
| authorships[6].author.display_name | Katharina Rump |
| authorships[6].countries | DE |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[6].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[6].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[6].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[6].institutions[0].type | healthcare |
| authorships[6].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[6].institutions[0].country_code | DE |
| authorships[6].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Katharina Rump |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[7].author.id | https://openalex.org/A5001396029 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-1013-0015 |
| authorships[7].author.display_name | Birte Dyck |
| authorships[7].countries | DE |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[7].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[7].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[7].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[7].institutions[0].country_code | DE |
| authorships[7].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Birte Dyck |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[8].author.id | https://openalex.org/A5026735675 |
| authorships[8].author.orcid | https://orcid.org/0009-0008-9553-6575 |
| authorships[8].author.display_name | Lars Palmowski |
| authorships[8].countries | DE |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[8].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[8].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[8].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[8].institutions[0].country_code | DE |
| authorships[8].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Lars Palmowski |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[9].author.id | https://openalex.org/A5005922313 |
| authorships[9].author.orcid | |
| authorships[9].author.display_name | Britta Marko |
| authorships[9].countries | DE |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[9].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[9].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[9].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[9].institutions[0].type | healthcare |
| authorships[9].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[9].institutions[0].country_code | DE |
| authorships[9].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Britta Marko |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[10].author.id | https://openalex.org/A5051446675 |
| authorships[10].author.orcid | |
| authorships[10].author.display_name | Andrea Witowski |
| authorships[10].countries | DE |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[10].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[10].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[10].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[10].institutions[0].type | healthcare |
| authorships[10].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[10].institutions[0].country_code | DE |
| authorships[10].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Andrea Witowski |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[11].author.id | https://openalex.org/A5011944736 |
| authorships[11].author.orcid | |
| authorships[11].author.display_name | Katrin Willemsen |
| authorships[11].countries | DE |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[11].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[11].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[11].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[11].institutions[0].type | healthcare |
| authorships[11].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[11].institutions[0].country_code | DE |
| authorships[11].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Katrin Maria Willemsen |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[12].author.id | https://openalex.org/A5073546944 |
| authorships[12].author.orcid | https://orcid.org/0000-0002-3957-5448 |
| authorships[12].author.display_name | Stephanie Pfaender |
| authorships[12].countries | DE |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I904495901 |
| authorships[12].affiliations[0].raw_affiliation_string | Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany |
| authorships[12].institutions[0].id | https://openalex.org/I904495901 |
| authorships[12].institutions[0].ror | https://ror.org/04tsk2644 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I904495901 |
| authorships[12].institutions[0].country_code | DE |
| authorships[12].institutions[0].display_name | Ruhr University Bochum |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Stephanie Pfaender |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany |
| authorships[13].author.id | https://openalex.org/A5087611420 |
| authorships[13].author.orcid | https://orcid.org/0000-0003-2687-7444 |
| authorships[13].author.display_name | Martin Eisenacher |
| authorships[13].countries | DE |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I904495901 |
| authorships[13].affiliations[0].raw_affiliation_string | Medical Proteome Analysis, Center for Proteindiagnostics (PRODI), Ruhr University Bochum, Bochum, Germany |
| authorships[13].affiliations[1].institution_ids | https://openalex.org/I904495901 |
| authorships[13].affiliations[1].raw_affiliation_string | Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[13].institutions[0].id | https://openalex.org/I904495901 |
| authorships[13].institutions[0].ror | https://ror.org/04tsk2644 |
| authorships[13].institutions[0].type | education |
| authorships[13].institutions[0].lineage | https://openalex.org/I904495901 |
| authorships[13].institutions[0].country_code | DE |
| authorships[13].institutions[0].display_name | Ruhr University Bochum |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Martin Eisenacher |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Medical Proteome Analysis, Center for Proteindiagnostics (PRODI), Ruhr University Bochum, Bochum, Germany, Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[14].author.id | https://openalex.org/A5091199070 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-4549-2286 |
| authorships[14].author.display_name | Moritz Anft |
| authorships[14].countries | DE |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I4210088550, https://openalex.org/I904495901 |
| authorships[14].affiliations[0].raw_affiliation_string | Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany |
| authorships[14].institutions[0].id | https://openalex.org/I904495901 |
| authorships[14].institutions[0].ror | https://ror.org/04tsk2644 |
| authorships[14].institutions[0].type | education |
| authorships[14].institutions[0].lineage | https://openalex.org/I904495901 |
| authorships[14].institutions[0].country_code | DE |
| authorships[14].institutions[0].display_name | Ruhr University Bochum |
| authorships[14].institutions[1].id | https://openalex.org/I4210088550 |
| authorships[14].institutions[1].ror | https://ror.org/004h6mc53 |
| authorships[14].institutions[1].type | healthcare |
| authorships[14].institutions[1].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210088550 |
| authorships[14].institutions[1].country_code | DE |
| authorships[14].institutions[1].display_name | Universitätsklinik Marien Hospital Herne |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Moritz Anft |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany |
| authorships[15].author.id | https://openalex.org/A5037283048 |
| authorships[15].author.orcid | https://orcid.org/0000-0003-3673-712X |
| authorships[15].author.display_name | Nina Babel |
| authorships[15].countries | DE |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I4210088550, https://openalex.org/I904495901 |
| authorships[15].affiliations[0].raw_affiliation_string | Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany |
| authorships[15].institutions[0].id | https://openalex.org/I904495901 |
| authorships[15].institutions[0].ror | https://ror.org/04tsk2644 |
| authorships[15].institutions[0].type | education |
| authorships[15].institutions[0].lineage | https://openalex.org/I904495901 |
| authorships[15].institutions[0].country_code | DE |
| authorships[15].institutions[0].display_name | Ruhr University Bochum |
| authorships[15].institutions[1].id | https://openalex.org/I4210088550 |
| authorships[15].institutions[1].ror | https://ror.org/004h6mc53 |
| authorships[15].institutions[1].type | healthcare |
| authorships[15].institutions[1].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210088550 |
| authorships[15].institutions[1].country_code | DE |
| authorships[15].institutions[1].display_name | Universitätsklinik Marien Hospital Herne |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Nina Babel |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany |
| authorships[16].author.id | https://openalex.org/A5003544336 |
| authorships[16].author.orcid | https://orcid.org/0000-0002-1194-6614 |
| authorships[16].author.display_name | Thilo Bracht |
| authorships[16].countries | DE |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[16].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[16].affiliations[1].institution_ids | https://openalex.org/I904495901 |
| authorships[16].affiliations[1].raw_affiliation_string | Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[16].institutions[0].id | https://openalex.org/I904495901 |
| authorships[16].institutions[0].ror | https://ror.org/04tsk2644 |
| authorships[16].institutions[0].type | education |
| authorships[16].institutions[0].lineage | https://openalex.org/I904495901 |
| authorships[16].institutions[0].country_code | DE |
| authorships[16].institutions[0].display_name | Ruhr University Bochum |
| authorships[16].institutions[1].id | https://openalex.org/I4210112654 |
| authorships[16].institutions[1].ror | https://ror.org/024j3hn90 |
| authorships[16].institutions[1].type | healthcare |
| authorships[16].institutions[1].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[16].institutions[1].country_code | DE |
| authorships[16].institutions[1].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Thilo Bracht |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany, Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[17].author.id | https://openalex.org/A5063961467 |
| authorships[17].author.orcid | |
| authorships[17].author.display_name | Barbara Sitek |
| authorships[17].countries | DE |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[17].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[17].affiliations[1].institution_ids | https://openalex.org/I904495901 |
| authorships[17].affiliations[1].raw_affiliation_string | Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[17].institutions[0].id | https://openalex.org/I904495901 |
| authorships[17].institutions[0].ror | https://ror.org/04tsk2644 |
| authorships[17].institutions[0].type | education |
| authorships[17].institutions[0].lineage | https://openalex.org/I904495901 |
| authorships[17].institutions[0].country_code | DE |
| authorships[17].institutions[0].display_name | Ruhr University Bochum |
| authorships[17].institutions[1].id | https://openalex.org/I4210112654 |
| authorships[17].institutions[1].ror | https://ror.org/024j3hn90 |
| authorships[17].institutions[1].type | healthcare |
| authorships[17].institutions[1].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[17].institutions[1].country_code | DE |
| authorships[17].institutions[1].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | Barbara Sitek |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany, Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[18].author.id | https://openalex.org/A5000727353 |
| authorships[18].author.orcid | https://orcid.org/0000-0003-1060-8856 |
| authorships[18].author.display_name | Malte Bayer |
| authorships[18].countries | DE |
| authorships[18].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[18].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[18].affiliations[1].institution_ids | https://openalex.org/I904495901 |
| authorships[18].affiliations[1].raw_affiliation_string | Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[18].institutions[0].id | https://openalex.org/I904495901 |
| authorships[18].institutions[0].ror | https://ror.org/04tsk2644 |
| authorships[18].institutions[0].type | education |
| authorships[18].institutions[0].lineage | https://openalex.org/I904495901 |
| authorships[18].institutions[0].country_code | DE |
| authorships[18].institutions[0].display_name | Ruhr University Bochum |
| authorships[18].institutions[1].id | https://openalex.org/I4210112654 |
| authorships[18].institutions[1].ror | https://ror.org/024j3hn90 |
| authorships[18].institutions[1].type | healthcare |
| authorships[18].institutions[1].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[18].institutions[1].country_code | DE |
| authorships[18].institutions[1].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[18].author_position | middle |
| authorships[18].raw_author_name | Malte Bayer |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany, Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany |
| authorships[19].author.id | https://openalex.org/A5019726220 |
| authorships[19].author.orcid | https://orcid.org/0000-0002-2124-1714 |
| authorships[19].author.display_name | Alexander Zarbock |
| authorships[19].countries | DE |
| authorships[19].affiliations[0].institution_ids | https://openalex.org/I4210103666 |
| authorships[19].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Operative Intensivmedizin und Schmerztherapie, Universitätsklinikum Münster, Münster, Germany |
| authorships[19].institutions[0].id | https://openalex.org/I4210103666 |
| authorships[19].institutions[0].ror | https://ror.org/01856cw59 |
| authorships[19].institutions[0].type | healthcare |
| authorships[19].institutions[0].lineage | https://openalex.org/I4210103666 |
| authorships[19].institutions[0].country_code | DE |
| authorships[19].institutions[0].display_name | University Hospital Münster |
| authorships[19].author_position | middle |
| authorships[19].raw_author_name | Alexander Zarbock |
| authorships[19].is_corresponding | False |
| authorships[19].raw_affiliation_strings | Klinik für Anästhesiologie, Operative Intensivmedizin und Schmerztherapie, Universitätsklinikum Münster, Münster, Germany |
| authorships[20].author.id | https://openalex.org/A5000766210 |
| authorships[20].author.orcid | https://orcid.org/0000-0002-5287-1137 |
| authorships[20].author.display_name | Thilo von Groote |
| authorships[20].countries | DE |
| authorships[20].affiliations[0].institution_ids | https://openalex.org/I4210103666 |
| authorships[20].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Operative Intensivmedizin und Schmerztherapie, Universitätsklinikum Münster, Münster, Germany |
| authorships[20].institutions[0].id | https://openalex.org/I4210103666 |
| authorships[20].institutions[0].ror | https://ror.org/01856cw59 |
| authorships[20].institutions[0].type | healthcare |
| authorships[20].institutions[0].lineage | https://openalex.org/I4210103666 |
| authorships[20].institutions[0].country_code | DE |
| authorships[20].institutions[0].display_name | University Hospital Münster |
| authorships[20].author_position | middle |
| authorships[20].raw_author_name | Thilo von Groote |
| authorships[20].is_corresponding | False |
| authorships[20].raw_affiliation_strings | Klinik für Anästhesiologie, Operative Intensivmedizin und Schmerztherapie, Universitätsklinikum Münster, Münster, Germany |
| authorships[21].author.id | https://openalex.org/A5040689704 |
| authorships[21].author.orcid | https://orcid.org/0000-0003-1599-9809 |
| authorships[21].author.display_name | Christian Putensen |
| authorships[21].countries | DE |
| authorships[21].affiliations[0].institution_ids | https://openalex.org/I2799391451 |
| authorships[21].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, Bonn, Germany |
| authorships[21].institutions[0].id | https://openalex.org/I2799391451 |
| authorships[21].institutions[0].ror | https://ror.org/01xnwqx93 |
| authorships[21].institutions[0].type | healthcare |
| authorships[21].institutions[0].lineage | https://openalex.org/I2799391451 |
| authorships[21].institutions[0].country_code | DE |
| authorships[21].institutions[0].display_name | University Hospital Bonn |
| authorships[21].author_position | middle |
| authorships[21].raw_author_name | Christian Putensen |
| authorships[21].is_corresponding | False |
| authorships[21].raw_affiliation_strings | Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, Bonn, Germany |
| authorships[22].author.id | https://openalex.org/A5007850731 |
| authorships[22].author.orcid | https://orcid.org/0000-0001-5747-6737 |
| authorships[22].author.display_name | Stefan Ehrentraut |
| authorships[22].countries | DE |
| authorships[22].affiliations[0].institution_ids | https://openalex.org/I2799391451 |
| authorships[22].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, Bonn, Germany |
| authorships[22].institutions[0].id | https://openalex.org/I2799391451 |
| authorships[22].institutions[0].ror | https://ror.org/01xnwqx93 |
| authorships[22].institutions[0].type | healthcare |
| authorships[22].institutions[0].lineage | https://openalex.org/I2799391451 |
| authorships[22].institutions[0].country_code | DE |
| authorships[22].institutions[0].display_name | University Hospital Bonn |
| authorships[22].author_position | middle |
| authorships[22].raw_author_name | Stefan Felix Ehrentraut |
| authorships[22].is_corresponding | False |
| authorships[22].raw_affiliation_strings | Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, Bonn, Germany |
| authorships[23].author.id | https://openalex.org/A5091785083 |
| authorships[23].author.orcid | https://orcid.org/0000-0002-7647-1613 |
| authorships[23].author.display_name | Christina Weisheit |
| authorships[23].countries | DE |
| authorships[23].affiliations[0].institution_ids | https://openalex.org/I2799391451 |
| authorships[23].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, Bonn, Germany |
| authorships[23].institutions[0].id | https://openalex.org/I2799391451 |
| authorships[23].institutions[0].ror | https://ror.org/01xnwqx93 |
| authorships[23].institutions[0].type | healthcare |
| authorships[23].institutions[0].lineage | https://openalex.org/I2799391451 |
| authorships[23].institutions[0].country_code | DE |
| authorships[23].institutions[0].display_name | University Hospital Bonn |
| authorships[23].author_position | middle |
| authorships[23].raw_author_name | Christina Weisheit |
| authorships[23].is_corresponding | False |
| authorships[23].raw_affiliation_strings | Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, Bonn, Germany |
| authorships[24].author.id | https://openalex.org/A5055659856 |
| authorships[24].author.orcid | https://orcid.org/0000-0002-7188-4873 |
| authorships[24].author.display_name | Michael Adamzik |
| authorships[24].countries | DE |
| authorships[24].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[24].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[24].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[24].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[24].institutions[0].type | healthcare |
| authorships[24].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[24].institutions[0].country_code | DE |
| authorships[24].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[24].author_position | middle |
| authorships[24].raw_author_name | Michael Adamzik |
| authorships[24].is_corresponding | False |
| authorships[24].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[25].author.id | https://openalex.org/A5011305401 |
| authorships[25].author.orcid | https://orcid.org/0000-0002-1500-1984 |
| authorships[25].author.display_name | Matthias Unterberg |
| authorships[25].countries | DE |
| authorships[25].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[25].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[25].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[25].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[25].institutions[0].type | healthcare |
| authorships[25].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[25].institutions[0].country_code | DE |
| authorships[25].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[25].author_position | middle |
| authorships[25].raw_author_name | Matthias Unterberg |
| authorships[25].is_corresponding | True |
| authorships[25].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[26].author.id | https://openalex.org/A5051184588 |
| authorships[26].author.orcid | https://orcid.org/0000-0002-0544-4124 |
| authorships[26].author.display_name | Björn Koos |
| authorships[26].countries | DE |
| authorships[26].affiliations[0].institution_ids | https://openalex.org/I4210112654 |
| authorships[26].affiliations[0].raw_affiliation_string | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| authorships[26].institutions[0].id | https://openalex.org/I4210112654 |
| authorships[26].institutions[0].ror | https://ror.org/024j3hn90 |
| authorships[26].institutions[0].type | healthcare |
| authorships[26].institutions[0].lineage | https://openalex.org/I2799784675, https://openalex.org/I4210112654 |
| authorships[26].institutions[0].country_code | DE |
| authorships[26].institutions[0].display_name | Universitätsklinikum Knappschaftskrankenhaus Bochum |
| authorships[26].author_position | last |
| authorships[26].raw_author_name | Björn Koos |
| authorships[26].is_corresponding | False |
| authorships[26].raw_affiliation_strings | Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1386586/pdf |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Exploring the relationship between HCMV serostatus and outcomes in COVID-19 sepsis |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T06:51:31.235846 |
| primary_topic.id | https://openalex.org/T10218 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9984999895095825 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2713 |
| primary_topic.subfield.display_name | Epidemiology |
| primary_topic.display_name | Sepsis Diagnosis and Treatment |
| related_works | https://openalex.org/W2075010788, https://openalex.org/W2124140405, https://openalex.org/W2138426110, https://openalex.org/W2003666163, https://openalex.org/W1994465650, https://openalex.org/W2037102991, https://openalex.org/W1987455384, https://openalex.org/W2047973812, https://openalex.org/W2971477903, https://openalex.org/W3190157138 |
| cited_by_count | 2 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 1 |
| locations_count | 4 |
| best_oa_location.id | doi:10.3389/fimmu.2024.1386586 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2595292759 |
| best_oa_location.source.issn | 1664-3224 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1664-3224 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Frontiers in Immunology |
| best_oa_location.source.host_organization | https://openalex.org/P4310320527 |
| best_oa_location.source.host_organization_name | Frontiers Media |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320527 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1386586/pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Frontiers in Immunology |
| best_oa_location.landing_page_url | https://doi.org/10.3389/fimmu.2024.1386586 |
| primary_location.id | doi:10.3389/fimmu.2024.1386586 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2595292759 |
| primary_location.source.issn | 1664-3224 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1664-3224 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Frontiers in Immunology |
| primary_location.source.host_organization | https://openalex.org/P4310320527 |
| primary_location.source.host_organization_name | Frontiers Media |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320527 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1386586/pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Frontiers in Immunology |
| primary_location.landing_page_url | https://doi.org/10.3389/fimmu.2024.1386586 |
| publication_date | 2024-05-08 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W3128078191, https://openalex.org/W3098790758, https://openalex.org/W2901929987, https://openalex.org/W1898928487, https://openalex.org/W2280404143, https://openalex.org/W3182386410, https://openalex.org/W2894422883, https://openalex.org/W2035509260, https://openalex.org/W1965154773, https://openalex.org/W6639175370, https://openalex.org/W3019247800, https://openalex.org/W3190290982, https://openalex.org/W4306167283, https://openalex.org/W3211813296, https://openalex.org/W3169047476, https://openalex.org/W3209538173, https://openalex.org/W3190442895, https://openalex.org/W4388089356, https://openalex.org/W1492950536, https://openalex.org/W1976978388, https://openalex.org/W2588030598, https://openalex.org/W1965298358, https://openalex.org/W2143012846, https://openalex.org/W3010634832, https://openalex.org/W3121465336, https://openalex.org/W4388582430, https://openalex.org/W4362668361, https://openalex.org/W4309510532, https://openalex.org/W2759168201, https://openalex.org/W2161911625, https://openalex.org/W2158154689, https://openalex.org/W2115364134, https://openalex.org/W4210627986, https://openalex.org/W4281556208, https://openalex.org/W2979874232, https://openalex.org/W2407434056, https://openalex.org/W2100637490, https://openalex.org/W2783891746, https://openalex.org/W4309516074, https://openalex.org/W4210792795, https://openalex.org/W2972917228, https://openalex.org/W1874876720, https://openalex.org/W4224299048 |
| referenced_works_count | 43 |
| abstract_inverted_index.+ | 200 |
| abstract_inverted_index.= | 126, 155 |
| abstract_inverted_index.A | 58 |
| abstract_inverted_index.a | 2, 14, 46, 217 |
| abstract_inverted_index.p | 125, 154 |
| abstract_inverted_index.80 | 71 |
| abstract_inverted_index.95 | 63 |
| abstract_inverted_index.an | 81, 184 |
| abstract_inverted_index.as | 45, 74 |
| abstract_inverted_index.be | 191 |
| abstract_inverted_index.by | 6, 193 |
| abstract_inverted_index.in | 27, 53, 128, 143, 177, 263, 276, 306 |
| abstract_inverted_index.is | 13, 29, 229 |
| abstract_inverted_index.of | 22, 51, 110, 183, 196, 216, 224, 236, 271, 312 |
| abstract_inverted_index.on | 187, 273, 291 |
| abstract_inverted_index.or | 24 |
| abstract_inverted_index.to | 11, 38, 148, 210, 231, 267 |
| abstract_inverted_index.vs | 151 |
| abstract_inverted_index.CD8 | 199 |
| abstract_inverted_index.The | 108, 214 |
| abstract_inverted_index.aid | 305 |
| abstract_inverted_index.and | 70, 90, 103, 122, 174, 243, 259, 300, 309 |
| abstract_inverted_index.can | 190 |
| abstract_inverted_index.did | 113, 160, 281 |
| abstract_inverted_index.for | 31, 49, 246, 315 |
| abstract_inverted_index.not | 114, 161, 282 |
| abstract_inverted_index.the | 7, 20, 40, 98, 129, 169, 181, 194, 222, 225, 233, 254, 268, 293, 310 |
| abstract_inverted_index.was | 78, 140 |
| abstract_inverted_index.(86% | 150 |
| abstract_inverted_index.61%, | 152 |
| abstract_inverted_index.HCMV | 76, 101, 111, 138, 158, 172, 197, 211, 257, 279 |
| abstract_inverted_index.This | 35, 251 |
| abstract_inverted_index.aged | 135 |
| abstract_inverted_index.body | 270 |
| abstract_inverted_index.care | 65 |
| abstract_inverted_index.host | 9 |
| abstract_inverted_index.lack | 182 |
| abstract_inverted_index.risk | 47, 307 |
| abstract_inverted_index.some | 208 |
| abstract_inverted_index.this | 237 |
| abstract_inverted_index.were | 93 |
| abstract_inverted_index.will | 304 |
| abstract_inverted_index.with | 55, 67 |
| abstract_inverted_index.(71%, | 124 |
| abstract_inverted_index.(78%) | 121 |
| abstract_inverted_index.ELISA | 82 |
| abstract_inverted_index.HCMV, | 297 |
| abstract_inverted_index.These | 166, 302 |
| abstract_inverted_index.aimed | 37 |
| abstract_inverted_index.among | 133 |
| abstract_inverted_index.data, | 86 |
| abstract_inverted_index.focus | 290 |
| abstract_inverted_index.group | 220 |
| abstract_inverted_index.human | 41 |
| abstract_inverted_index.major | 15 |
| abstract_inverted_index.might | 206 |
| abstract_inverted_index.study | 36, 61, 252 |
| abstract_inverted_index.test. | 83 |
| abstract_inverted_index.using | 80 |
| abstract_inverted_index.viral | 23, 274, 316 |
| abstract_inverted_index.which | 205 |
| abstract_inverted_index.≤60 | 136 |
| abstract_inverted_index.(HCMV) | 43 |
| abstract_inverted_index.0.382) | 127 |
| abstract_inverted_index.30-day | 91, 163, 188, 285 |
| abstract_inverted_index.affect | 162 |
| abstract_inverted_index.caused | 5 |
| abstract_inverted_index.confer | 207 |
| abstract_inverted_index.differ | 116 |
| abstract_inverted_index.effect | 186 |
| abstract_inverted_index.entire | 130 |
| abstract_inverted_index.factor | 48 |
| abstract_inverted_index.future | 287 |
| abstract_inverted_index.global | 16 |
| abstract_inverted_index.health | 17 |
| abstract_inverted_index.higher | 142 |
| abstract_inverted_index.immune | 298 |
| abstract_inverted_index.impact | 21 |
| abstract_inverted_index.needed | 230 |
| abstract_inverted_index.sepsis | 28, 52, 69, 119, 145, 176, 262 |
| abstract_inverted_index.severe | 260 |
| abstract_inverted_index.should | 289 |
| abstract_inverted_index.years, | 137 |
| abstract_inverted_index.0.030). | 156 |
| abstract_inverted_index.Further | 227 |
| abstract_inverted_index.Methods | 57 |
| abstract_inverted_index.Results | 107 |
| abstract_inverted_index.Sepsis, | 1 |
| abstract_inverted_index.T-cells | 201 |
| abstract_inverted_index.between | 100, 117, 171, 256, 296 |
| abstract_inverted_index.cohort. | 131 |
| abstract_inverted_index.confirm | 168 |
| abstract_inverted_index.control | 219 |
| abstract_inverted_index.crucial | 30 |
| abstract_inverted_index.explore | 239 |
| abstract_inverted_index.growing | 269 |
| abstract_inverted_index.induced | 105 |
| abstract_inverted_index.patient | 33, 241, 248 |
| abstract_inverted_index.sepsis. | 106, 277, 317 |
| abstract_inverted_index.towards | 202 |
| abstract_inverted_index.Although | 278 |
| abstract_inverted_index.COVID-19 | 104, 144, 175 |
| abstract_inverted_index.However, | 132, 180 |
| abstract_inverted_index.analyses | 96 |
| abstract_inverted_index.clinical | 85 |
| abstract_inverted_index.compared | 147 |
| abstract_inverted_index.concern. | 18 |
| abstract_inverted_index.controls | 123, 149 |
| abstract_inverted_index.enrolled | 62 |
| abstract_inverted_index.evidence | 272 |
| abstract_inverted_index.findings | 167 |
| abstract_inverted_index.identify | 244 |
| abstract_inverted_index.insights | 303 |
| abstract_inverted_index.patients | 54, 66, 120, 134, 146 |
| abstract_inverted_index.research | 228 |
| abstract_inverted_index.response | 10 |
| abstract_inverted_index.specific | 198 |
| abstract_inverted_index.survival | 189 |
| abstract_inverted_index.targeted | 313 |
| abstract_inverted_index.COVID-19. | 56, 301 |
| abstract_inverted_index.bacterial | 25 |
| abstract_inverted_index.condition | 4 |
| abstract_inverted_index.controls. | 75 |
| abstract_inverted_index.different | 240 |
| abstract_inverted_index.elucidate | 232 |
| abstract_inverted_index.evaluated | 97 |
| abstract_inverted_index.explained | 192 |
| abstract_inverted_index.findings. | 226 |
| abstract_inverted_index.improving | 32 |
| abstract_inverted_index.including | 87 |
| abstract_inverted_index.inclusion | 215 |
| abstract_inverted_index.influence | 284 |
| abstract_inverted_index.intensive | 64 |
| abstract_inverted_index.interplay | 295 |
| abstract_inverted_index.intricate | 294 |
| abstract_inverted_index.outcomes. | 34 |
| abstract_inverted_index.pathogens | 26, 275 |
| abstract_inverted_index.patients, | 265 |
| abstract_inverted_index.patients. | 179, 213 |
| abstract_inverted_index.peptides, | 204 |
| abstract_inverted_index.survival, | 286 |
| abstract_inverted_index.survival. | 164 |
| abstract_inverted_index.validates | 253 |
| abstract_inverted_index.Background | 0 |
| abstract_inverted_index.Conclusion | 250 |
| abstract_inverted_index.Discussion | 165 |
| abstract_inverted_index.SARS-CoV-2 | 203 |
| abstract_inverted_index.collected. | 94 |
| abstract_inverted_index.determined | 79 |
| abstract_inverted_index.infection, | 12 |
| abstract_inverted_index.mechanisms | 235 |
| abstract_inverted_index.mortality, | 92 |
| abstract_inverted_index.optimizing | 247 |
| abstract_inverted_index.prevalence | 109 |
| abstract_inverted_index.protection | 209 |
| abstract_inverted_index.responses, | 299 |
| abstract_inverted_index.serostatus | 77, 159, 280 |
| abstract_inverted_index.underlying | 234 |
| abstract_inverted_index.unraveling | 292 |
| abstract_inverted_index.Statistical | 95 |
| abstract_inverted_index.association | 99, 170, 255 |
| abstract_inverted_index.development | 50, 311 |
| abstract_inverted_index.independent | 185 |
| abstract_inverted_index.individuals | 73 |
| abstract_inverted_index.investigate | 39 |
| abstract_inverted_index.management. | 249 |
| abstract_inverted_index.multicenter | 59 |
| abstract_inverted_index.strengthens | 221 |
| abstract_inverted_index.association, | 238 |
| abstract_inverted_index.contributing | 266 |
| abstract_inverted_index.dysregulated | 8 |
| abstract_inverted_index.populations, | 242 |
| abstract_inverted_index.post-surgery | 72, 218 |
| abstract_inverted_index.seropositive | 212 |
| abstract_inverted_index.Comprehensive | 84 |
| abstract_inverted_index.Nevertheless, | 157 |
| abstract_inverted_index.Understanding | 19 |
| abstract_inverted_index.demographics, | 88 |
| abstract_inverted_index.independently | 283 |
| abstract_inverted_index.interventions | 245, 314 |
| abstract_inverted_index.non-geriatric | 178, 264 |
| abstract_inverted_index.observational | 60 |
| abstract_inverted_index.respectively; | 153 |
| abstract_inverted_index.significantly | 115, 141 |
| abstract_inverted_index.comorbidities, | 89 |
| abstract_inverted_index.investigations | 288 |
| abstract_inverted_index.seropositivity | 44, 102, 112, 139, 173, 258 |
| abstract_inverted_index.stratification | 308 |
| abstract_inverted_index.cytomegalovirus | 42 |
| abstract_inverted_index.COVID-19-induced | 68, 118, 261 |
| abstract_inverted_index.cross-reactivity | 195 |
| abstract_inverted_index.generalizability | 223 |
| abstract_inverted_index.life-threatening | 3 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 90 |
| corresponding_author_ids | https://openalex.org/A5011305401 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 27 |
| corresponding_institution_ids | https://openalex.org/I4210112654 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.6299999952316284 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.76260131 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |