Expression of CD123 related long non-coding RNA in Acute Myeloid Leukemia bone marrow mononuclear cells and its clinical significance Article Swipe
Yanli Feng
,
Baoxiong Su
,
Yingying Xu
,
Yuchen He
,
Ranran He
,
Fan-Mei Ge
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.14715/cmb/2022.68.6.23
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.14715/cmb/2022.68.6.23
Acute myelogenous leukemia (AML) is a very common hematopoietic malignancy. Hematopoietic stem cell transplantation can improve the therapeutic effect of AML, but the 5-year survival rate is very low. CD123 imbalance, abnormal gene expression, and epigenetics play an important role in the pathogenesis of AML. This research was to explore the differential expression of CD123-related long non-coding RNA (lncRNA) in AML bone marrow mononuclear cells and provide a theoretical basis for targeted therapy of AML. High-throughput sequencing was performed to screen differentially expressed lncRNA in bone marrow mononuclear immunophenotypes of CD123+ and CD123- from patients with primary AML, and real-time quantitative PCR was adopted for screening and validation. There were 933 differentially expressed lncRNAs in the CD123+ group and the CD123- group, 407 lncRNAs were up-regulated and 463 lncRNAs were down-regulated in the CD123+ group. 14 lncRNAs with more than 2 times of difference were screened for identification, and it was found that compared with CD123- group, there was no substantial difference in the expression of JHDM1D-AS1, LINC01355, CASC15, FAM13A-AS1, HSPC324, LOC339803, LINC00877, and MAG12-AS3 in CD123+ group (P>0.05). The expressions of LOC101929698, BaALC-AS2, BOLA3-AS1, and FBX19-AS1 were considerably up-regulated (P<0.05), while the expressions of LOC100132249 and LINC02085 were considerably down-regulated (P<0.05). In summary, differentially expressed lncRNAs in bone marrow samples of CD123+ and CD123- group of newly diagnosed AML patients may be involved in the process of AML and seriously affect the prognosis of patients.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.14715/cmb/2022.68.6.23
- https://www.cellmolbiol.org/index.php/CMB/article/download/4440/2191
- OA Status
- hybrid
- Cited By
- 4
- References
- 33
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4306168041
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4306168041Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.14715/cmb/2022.68.6.23Digital Object Identifier
- Title
-
Expression of CD123 related long non-coding RNA in Acute Myeloid Leukemia bone marrow mononuclear cells and its clinical significanceWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-06-30Full publication date if available
- Authors
-
Yanli Feng, Baoxiong Su, Yingying Xu, Yuchen He, Ranran He, Fan-Mei GeList of authors in order
- Landing page
-
https://doi.org/10.14715/cmb/2022.68.6.23Publisher landing page
- PDF URL
-
https://www.cellmolbiol.org/index.php/CMB/article/download/4440/2191Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://www.cellmolbiol.org/index.php/CMB/article/download/4440/2191Direct OA link when available
- Concepts
-
Myeloid leukemia, Bone marrow, Peripheral blood mononuclear cell, Medicine, Clinical significance, RNA, Leukemia, Myeloid, Cancer research, Biology, Immunology, Pathology, Gene, Genetics, In vitroTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
4Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 2, 2023: 2Per-year citation counts (last 5 years)
- References (count)
-
33Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4306168041 |
|---|---|
| doi | https://doi.org/10.14715/cmb/2022.68.6.23 |
| ids.doi | https://doi.org/10.14715/cmb/2022.68.6.23 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/36227664 |
| ids.openalex | https://openalex.org/W4306168041 |
| fwci | 0.54382606 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D001853 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Bone Marrow |
| mesh[1].qualifier_ui | Q000627 |
| mesh[1].descriptor_ui | D020690 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | therapeutic use |
| mesh[1].descriptor_name | GTPase-Activating Proteins |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D006801 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Humans |
| mesh[3].qualifier_ui | Q000235 |
| mesh[3].descriptor_ui | D053650 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | genetics |
| mesh[3].descriptor_name | Interleukin-3 Receptor alpha Subunit |
| mesh[4].qualifier_ui | Q000627 |
| mesh[4].descriptor_ui | D053650 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | therapeutic use |
| mesh[4].descriptor_name | Interleukin-3 Receptor alpha Subunit |
| mesh[5].qualifier_ui | Q000188 |
| mesh[5].descriptor_ui | D015470 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | drug therapy |
| mesh[5].descriptor_name | Leukemia, Myeloid, Acute |
| mesh[6].qualifier_ui | Q000235 |
| mesh[6].descriptor_ui | D015470 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | genetics |
| mesh[6].descriptor_name | Leukemia, Myeloid, Acute |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D024101 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Mitochondrial Proteins |
| mesh[8].qualifier_ui | Q000235 |
| mesh[8].descriptor_ui | D062085 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | genetics |
| mesh[8].descriptor_name | RNA, Long Noncoding |
| mesh[9].qualifier_ui | Q000378 |
| mesh[9].descriptor_ui | D062085 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | metabolism |
| mesh[9].descriptor_name | RNA, Long Noncoding |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D001853 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Bone Marrow |
| mesh[11].qualifier_ui | Q000627 |
| mesh[11].descriptor_ui | D020690 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | therapeutic use |
| mesh[11].descriptor_name | GTPase-Activating Proteins |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D006801 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Humans |
| mesh[13].qualifier_ui | Q000235 |
| mesh[13].descriptor_ui | D053650 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | genetics |
| mesh[13].descriptor_name | Interleukin-3 Receptor alpha Subunit |
| mesh[14].qualifier_ui | Q000627 |
| mesh[14].descriptor_ui | D053650 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | therapeutic use |
| mesh[14].descriptor_name | Interleukin-3 Receptor alpha Subunit |
| mesh[15].qualifier_ui | Q000188 |
| mesh[15].descriptor_ui | D015470 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | drug therapy |
| mesh[15].descriptor_name | Leukemia, Myeloid, Acute |
| mesh[16].qualifier_ui | Q000235 |
| mesh[16].descriptor_ui | D015470 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | genetics |
| mesh[16].descriptor_name | Leukemia, Myeloid, Acute |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D024101 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Mitochondrial Proteins |
| mesh[18].qualifier_ui | Q000235 |
| mesh[18].descriptor_ui | D062085 |
| mesh[18].is_major_topic | True |
| mesh[18].qualifier_name | genetics |
| mesh[18].descriptor_name | RNA, Long Noncoding |
| mesh[19].qualifier_ui | Q000378 |
| mesh[19].descriptor_ui | D062085 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | metabolism |
| mesh[19].descriptor_name | RNA, Long Noncoding |
| type | article |
| title | Expression of CD123 related long non-coding RNA in Acute Myeloid Leukemia bone marrow mononuclear cells and its clinical significance |
| biblio.issue | 6 |
| biblio.volume | 68 |
| biblio.last_page | 147 |
| biblio.first_page | 140 |
| topics[0].id | https://openalex.org/T10515 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9988999962806702 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1306 |
| topics[0].subfield.display_name | Cancer Research |
| topics[0].display_name | Cancer-related molecular mechanisms research |
| topics[1].id | https://openalex.org/T11316 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.991599977016449 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2713 |
| topics[1].subfield.display_name | Epidemiology |
| topics[1].display_name | Mycobacterium research and diagnosis |
| topics[2].id | https://openalex.org/T11503 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9472000002861023 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2730 |
| topics[2].subfield.display_name | Oncology |
| topics[2].display_name | Cytokine Signaling Pathways and Interactions |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2778729363 |
| concepts[0].level | 2 |
| concepts[0].score | 0.7063910365104675 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11688946 |
| concepts[0].display_name | Myeloid leukemia |
| concepts[1].id | https://openalex.org/C2780007613 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7018759250640869 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q546523 |
| concepts[1].display_name | Bone marrow |
| concepts[2].id | https://openalex.org/C137061746 |
| concepts[2].level | 3 |
| concepts[2].score | 0.6859722137451172 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q736033 |
| concepts[2].display_name | Peripheral blood mononuclear cell |
| concepts[3].id | https://openalex.org/C71924100 |
| concepts[3].level | 0 |
| concepts[3].score | 0.49249109625816345 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[3].display_name | Medicine |
| concepts[4].id | https://openalex.org/C63363279 |
| concepts[4].level | 2 |
| concepts[4].score | 0.48060959577560425 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q5133848 |
| concepts[4].display_name | Clinical significance |
| concepts[5].id | https://openalex.org/C67705224 |
| concepts[5].level | 3 |
| concepts[5].score | 0.480089008808136 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q11053 |
| concepts[5].display_name | RNA |
| concepts[6].id | https://openalex.org/C2778461978 |
| concepts[6].level | 2 |
| concepts[6].score | 0.431439608335495 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q29496 |
| concepts[6].display_name | Leukemia |
| concepts[7].id | https://openalex.org/C2779282312 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4250306487083435 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1956561 |
| concepts[7].display_name | Myeloid |
| concepts[8].id | https://openalex.org/C502942594 |
| concepts[8].level | 1 |
| concepts[8].score | 0.42152905464172363 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q3421914 |
| concepts[8].display_name | Cancer research |
| concepts[9].id | https://openalex.org/C86803240 |
| concepts[9].level | 0 |
| concepts[9].score | 0.37709927558898926 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[9].display_name | Biology |
| concepts[10].id | https://openalex.org/C203014093 |
| concepts[10].level | 1 |
| concepts[10].score | 0.35347920656204224 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q101929 |
| concepts[10].display_name | Immunology |
| concepts[11].id | https://openalex.org/C142724271 |
| concepts[11].level | 1 |
| concepts[11].score | 0.30120524764060974 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q7208 |
| concepts[11].display_name | Pathology |
| concepts[12].id | https://openalex.org/C104317684 |
| concepts[12].level | 2 |
| concepts[12].score | 0.1524902880191803 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[12].display_name | Gene |
| concepts[13].id | https://openalex.org/C54355233 |
| concepts[13].level | 1 |
| concepts[13].score | 0.12833863496780396 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[13].display_name | Genetics |
| concepts[14].id | https://openalex.org/C202751555 |
| concepts[14].level | 2 |
| concepts[14].score | 0.06557539105415344 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q221681 |
| concepts[14].display_name | In vitro |
| keywords[0].id | https://openalex.org/keywords/myeloid-leukemia |
| keywords[0].score | 0.7063910365104675 |
| keywords[0].display_name | Myeloid leukemia |
| keywords[1].id | https://openalex.org/keywords/bone-marrow |
| keywords[1].score | 0.7018759250640869 |
| keywords[1].display_name | Bone marrow |
| keywords[2].id | https://openalex.org/keywords/peripheral-blood-mononuclear-cell |
| keywords[2].score | 0.6859722137451172 |
| keywords[2].display_name | Peripheral blood mononuclear cell |
| keywords[3].id | https://openalex.org/keywords/medicine |
| keywords[3].score | 0.49249109625816345 |
| keywords[3].display_name | Medicine |
| keywords[4].id | https://openalex.org/keywords/clinical-significance |
| keywords[4].score | 0.48060959577560425 |
| keywords[4].display_name | Clinical significance |
| keywords[5].id | https://openalex.org/keywords/rna |
| keywords[5].score | 0.480089008808136 |
| keywords[5].display_name | RNA |
| keywords[6].id | https://openalex.org/keywords/leukemia |
| keywords[6].score | 0.431439608335495 |
| keywords[6].display_name | Leukemia |
| keywords[7].id | https://openalex.org/keywords/myeloid |
| keywords[7].score | 0.4250306487083435 |
| keywords[7].display_name | Myeloid |
| keywords[8].id | https://openalex.org/keywords/cancer-research |
| keywords[8].score | 0.42152905464172363 |
| keywords[8].display_name | Cancer research |
| keywords[9].id | https://openalex.org/keywords/biology |
| keywords[9].score | 0.37709927558898926 |
| keywords[9].display_name | Biology |
| keywords[10].id | https://openalex.org/keywords/immunology |
| keywords[10].score | 0.35347920656204224 |
| keywords[10].display_name | Immunology |
| keywords[11].id | https://openalex.org/keywords/pathology |
| keywords[11].score | 0.30120524764060974 |
| keywords[11].display_name | Pathology |
| keywords[12].id | https://openalex.org/keywords/gene |
| keywords[12].score | 0.1524902880191803 |
| keywords[12].display_name | Gene |
| keywords[13].id | https://openalex.org/keywords/genetics |
| keywords[13].score | 0.12833863496780396 |
| keywords[13].display_name | Genetics |
| keywords[14].id | https://openalex.org/keywords/in-vitro |
| keywords[14].score | 0.06557539105415344 |
| keywords[14].display_name | In vitro |
| language | en |
| locations[0].id | doi:10.14715/cmb/2022.68.6.23 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S21749381 |
| locations[0].source.issn | 0145-5680, 1165-158X |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0145-5680 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Cellular and Molecular Biology |
| locations[0].source.host_organization | https://openalex.org/P4322765267 |
| locations[0].source.host_organization_name | Cellular and Molecular Biology Association |
| locations[0].source.host_organization_lineage | https://openalex.org/P4322765267 |
| locations[0].source.host_organization_lineage_names | Cellular and Molecular Biology Association |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | https://www.cellmolbiol.org/index.php/CMB/article/download/4440/2191 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Cellular and Molecular Biology |
| locations[0].landing_page_url | https://doi.org/10.14715/cmb/2022.68.6.23 |
| locations[1].id | pmid:36227664 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Cellular and molecular biology (Noisy-le-Grand, France) |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/36227664 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5102475661 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-8059-8107 |
| authorships[0].author.display_name | Yanli Feng |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210102412 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[0].institutions[0].id | https://openalex.org/I4210102412 |
| authorships[0].institutions[0].ror | https://ror.org/01dyr7034 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I4210102412 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Yan'an University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | None Yanli Feng |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[1].author.id | https://openalex.org/A5012051906 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Baoxiong Su |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210102412 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[1].institutions[0].id | https://openalex.org/I4210102412 |
| authorships[1].institutions[0].ror | https://ror.org/01dyr7034 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210102412 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Yan'an University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | None Baoxiong Su |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[2].author.id | https://openalex.org/A5081643835 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-4924-9379 |
| authorships[2].author.display_name | Yingying Xu |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210102412 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[2].institutions[0].id | https://openalex.org/I4210102412 |
| authorships[2].institutions[0].ror | https://ror.org/01dyr7034 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210102412 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Yan'an University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | None Yingying Xu |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[3].author.id | https://openalex.org/A5100642696 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-3985-7779 |
| authorships[3].author.display_name | Yuchen He |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210102412 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[3].institutions[0].id | https://openalex.org/I4210102412 |
| authorships[3].institutions[0].ror | https://ror.org/01dyr7034 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210102412 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Yan'an University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | None Yuchen He |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[4].author.id | https://openalex.org/A5103878458 |
| authorships[4].author.orcid | |
| authorships[4].author.display_name | Ranran He |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210102412 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[4].institutions[0].id | https://openalex.org/I4210102412 |
| authorships[4].institutions[0].ror | https://ror.org/01dyr7034 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210102412 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Yan'an University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | None Ranran He |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[5].author.id | https://openalex.org/A5087245622 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Fan-Mei Ge |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210102412 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| authorships[5].institutions[0].id | https://openalex.org/I4210102412 |
| authorships[5].institutions[0].ror | https://ror.org/01dyr7034 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210102412 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | Yan'an University |
| authorships[5].author_position | last |
| authorships[5].raw_author_name | None Fanmei Ge |
| authorships[5].is_corresponding | True |
| authorships[5].raw_affiliation_strings | Department of Hematology, Affiliated Hospital of Yan' an University, Yan' an, 716000, Shaanxi Province, China |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.cellmolbiol.org/index.php/CMB/article/download/4440/2191 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Expression of CD123 related long non-coding RNA in Acute Myeloid Leukemia bone marrow mononuclear cells and its clinical significance |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10515 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9988999962806702 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1306 |
| primary_topic.subfield.display_name | Cancer Research |
| primary_topic.display_name | Cancer-related molecular mechanisms research |
| related_works | https://openalex.org/W2410819865, https://openalex.org/W1974500257, https://openalex.org/W2316586191, https://openalex.org/W2042480534, https://openalex.org/W3207807551, https://openalex.org/W2909695583, https://openalex.org/W2090016234, https://openalex.org/W2791968852, https://openalex.org/W1974032072, https://openalex.org/W42711520 |
| cited_by_count | 4 |
| counts_by_year[0].year | 2024 |
| counts_by_year[0].cited_by_count | 2 |
| counts_by_year[1].year | 2023 |
| counts_by_year[1].cited_by_count | 2 |
| locations_count | 2 |
| best_oa_location.id | doi:10.14715/cmb/2022.68.6.23 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S21749381 |
| best_oa_location.source.issn | 0145-5680, 1165-158X |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0145-5680 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Cellular and Molecular Biology |
| best_oa_location.source.host_organization | https://openalex.org/P4322765267 |
| best_oa_location.source.host_organization_name | Cellular and Molecular Biology Association |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4322765267 |
| best_oa_location.source.host_organization_lineage_names | Cellular and Molecular Biology Association |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | https://www.cellmolbiol.org/index.php/CMB/article/download/4440/2191 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Cellular and Molecular Biology |
| best_oa_location.landing_page_url | https://doi.org/10.14715/cmb/2022.68.6.23 |
| primary_location.id | doi:10.14715/cmb/2022.68.6.23 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S21749381 |
| primary_location.source.issn | 0145-5680, 1165-158X |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0145-5680 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Cellular and Molecular Biology |
| primary_location.source.host_organization | https://openalex.org/P4322765267 |
| primary_location.source.host_organization_name | Cellular and Molecular Biology Association |
| primary_location.source.host_organization_lineage | https://openalex.org/P4322765267 |
| primary_location.source.host_organization_lineage_names | Cellular and Molecular Biology Association |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | https://www.cellmolbiol.org/index.php/CMB/article/download/4440/2191 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Cellular and Molecular Biology |
| primary_location.landing_page_url | https://doi.org/10.14715/cmb/2022.68.6.23 |
| publication_date | 2022-06-30 |
| publication_year | 2022 |
| referenced_works | https://openalex.org/W3204486370, https://openalex.org/W3038313191, https://openalex.org/W2593230508, https://openalex.org/W2901191333, https://openalex.org/W2899472109, https://openalex.org/W3214170273, https://openalex.org/W2109336877, https://openalex.org/W3122576841, https://openalex.org/W3093708802, https://openalex.org/W4288400169, https://openalex.org/W2746759026, https://openalex.org/W3046492307, https://openalex.org/W3161975265, https://openalex.org/W3015589734, https://openalex.org/W3100577837, https://openalex.org/W3079197556, https://openalex.org/W3159418665, https://openalex.org/W3023646441, https://openalex.org/W2903930842, https://openalex.org/W3025100125, https://openalex.org/W2625600561, https://openalex.org/W2986494140, https://openalex.org/W3047297972, https://openalex.org/W3111811057, https://openalex.org/W2946736797, https://openalex.org/W3020803734, https://openalex.org/W3211447336, https://openalex.org/W3119810684, https://openalex.org/W2160026729, https://openalex.org/W3115260507, https://openalex.org/W3186638627, https://openalex.org/W134598806, https://openalex.org/W3014642785 |
| referenced_works_count | 33 |
| abstract_inverted_index.2 | 140 |
| abstract_inverted_index.a | 5, 67 |
| abstract_inverted_index.14 | 135 |
| abstract_inverted_index.In | 202 |
| abstract_inverted_index.an | 37 |
| abstract_inverted_index.be | 222 |
| abstract_inverted_index.in | 40, 59, 84, 114, 131, 162, 175, 207, 224 |
| abstract_inverted_index.is | 4, 26 |
| abstract_inverted_index.it | 149 |
| abstract_inverted_index.no | 159 |
| abstract_inverted_index.of | 19, 43, 53, 73, 89, 142, 165, 181, 194, 211, 216, 227, 234 |
| abstract_inverted_index.to | 48, 79 |
| abstract_inverted_index.407 | 122 |
| abstract_inverted_index.463 | 127 |
| abstract_inverted_index.933 | 110 |
| abstract_inverted_index.AML | 60, 219, 228 |
| abstract_inverted_index.PCR | 101 |
| abstract_inverted_index.RNA | 57 |
| abstract_inverted_index.The | 179 |
| abstract_inverted_index.and | 34, 65, 91, 98, 106, 118, 126, 148, 173, 185, 196, 213, 229 |
| abstract_inverted_index.but | 21 |
| abstract_inverted_index.can | 14 |
| abstract_inverted_index.for | 70, 104, 146 |
| abstract_inverted_index.may | 221 |
| abstract_inverted_index.the | 16, 22, 41, 50, 115, 119, 132, 163, 192, 225, 232 |
| abstract_inverted_index.was | 47, 77, 102, 150, 158 |
| abstract_inverted_index.AML, | 20, 97 |
| abstract_inverted_index.AML. | 44, 74 |
| abstract_inverted_index.This | 45 |
| abstract_inverted_index.bone | 61, 85, 208 |
| abstract_inverted_index.cell | 12 |
| abstract_inverted_index.from | 93 |
| abstract_inverted_index.gene | 32 |
| abstract_inverted_index.long | 55 |
| abstract_inverted_index.low. | 28 |
| abstract_inverted_index.more | 138 |
| abstract_inverted_index.play | 36 |
| abstract_inverted_index.rate | 25 |
| abstract_inverted_index.role | 39 |
| abstract_inverted_index.stem | 11 |
| abstract_inverted_index.than | 139 |
| abstract_inverted_index.that | 152 |
| abstract_inverted_index.very | 6, 27 |
| abstract_inverted_index.were | 109, 124, 129, 144, 187, 198 |
| abstract_inverted_index.with | 95, 137, 154 |
| abstract_inverted_index.(AML) | 3 |
| abstract_inverted_index.Acute | 0 |
| abstract_inverted_index.CD123 | 29 |
| abstract_inverted_index.There | 108 |
| abstract_inverted_index.basis | 69 |
| abstract_inverted_index.cells | 64 |
| abstract_inverted_index.found | 151 |
| abstract_inverted_index.group | 117, 177, 215 |
| abstract_inverted_index.newly | 217 |
| abstract_inverted_index.there | 157 |
| abstract_inverted_index.times | 141 |
| abstract_inverted_index.while | 191 |
| abstract_inverted_index.5-year | 23 |
| abstract_inverted_index.CD123+ | 90, 116, 133, 176, 212 |
| abstract_inverted_index.CD123- | 92, 120, 155, 214 |
| abstract_inverted_index.affect | 231 |
| abstract_inverted_index.common | 7 |
| abstract_inverted_index.effect | 18 |
| abstract_inverted_index.group, | 121, 156 |
| abstract_inverted_index.group. | 134 |
| abstract_inverted_index.lncRNA | 83 |
| abstract_inverted_index.marrow | 62, 86, 209 |
| abstract_inverted_index.screen | 80 |
| abstract_inverted_index.CASC15, | 168 |
| abstract_inverted_index.adopted | 103 |
| abstract_inverted_index.explore | 49 |
| abstract_inverted_index.improve | 15 |
| abstract_inverted_index.lncRNAs | 113, 123, 128, 136, 206 |
| abstract_inverted_index.primary | 96 |
| abstract_inverted_index.process | 226 |
| abstract_inverted_index.provide | 66 |
| abstract_inverted_index.samples | 210 |
| abstract_inverted_index.therapy | 72 |
| abstract_inverted_index.(lncRNA) | 58 |
| abstract_inverted_index.HSPC324, | 170 |
| abstract_inverted_index.abnormal | 31 |
| abstract_inverted_index.compared | 153 |
| abstract_inverted_index.involved | 223 |
| abstract_inverted_index.leukemia | 2 |
| abstract_inverted_index.patients | 94, 220 |
| abstract_inverted_index.research | 46 |
| abstract_inverted_index.screened | 145 |
| abstract_inverted_index.summary, | 203 |
| abstract_inverted_index.survival | 24 |
| abstract_inverted_index.targeted | 71 |
| abstract_inverted_index.(P<0.05), | 190 |
| abstract_inverted_index.(P<0.05). | 201 |
| abstract_inverted_index.(P>0.05). | 178 |
| abstract_inverted_index.FBX19-AS1 | 186 |
| abstract_inverted_index.LINC02085 | 197 |
| abstract_inverted_index.MAG12-AS3 | 174 |
| abstract_inverted_index.diagnosed | 218 |
| abstract_inverted_index.expressed | 82, 112, 205 |
| abstract_inverted_index.important | 38 |
| abstract_inverted_index.patients. | 235 |
| abstract_inverted_index.performed | 78 |
| abstract_inverted_index.prognosis | 233 |
| abstract_inverted_index.real-time | 99 |
| abstract_inverted_index.screening | 105 |
| abstract_inverted_index.seriously | 230 |
| abstract_inverted_index.BOLA3-AS1, | 184 |
| abstract_inverted_index.BaALC-AS2, | 183 |
| abstract_inverted_index.LINC00877, | 172 |
| abstract_inverted_index.LINC01355, | 167 |
| abstract_inverted_index.LOC339803, | 171 |
| abstract_inverted_index.difference | 143, 161 |
| abstract_inverted_index.expression | 52, 164 |
| abstract_inverted_index.imbalance, | 30 |
| abstract_inverted_index.non-coding | 56 |
| abstract_inverted_index.sequencing | 76 |
| abstract_inverted_index.FAM13A-AS1, | 169 |
| abstract_inverted_index.JHDM1D-AS1, | 166 |
| abstract_inverted_index.epigenetics | 35 |
| abstract_inverted_index.expression, | 33 |
| abstract_inverted_index.expressions | 180, 193 |
| abstract_inverted_index.malignancy. | 9 |
| abstract_inverted_index.mononuclear | 63, 87 |
| abstract_inverted_index.myelogenous | 1 |
| abstract_inverted_index.substantial | 160 |
| abstract_inverted_index.theoretical | 68 |
| abstract_inverted_index.therapeutic | 17 |
| abstract_inverted_index.validation. | 107 |
| abstract_inverted_index.LOC100132249 | 195 |
| abstract_inverted_index.considerably | 188, 199 |
| abstract_inverted_index.differential | 51 |
| abstract_inverted_index.pathogenesis | 42 |
| abstract_inverted_index.quantitative | 100 |
| abstract_inverted_index.up-regulated | 125, 189 |
| abstract_inverted_index.CD123-related | 54 |
| abstract_inverted_index.Hematopoietic | 10 |
| abstract_inverted_index.LOC101929698, | 182 |
| abstract_inverted_index.hematopoietic | 8 |
| abstract_inverted_index.differentially | 81, 111, 204 |
| abstract_inverted_index.down-regulated | 130, 200 |
| abstract_inverted_index.High-throughput | 75 |
| abstract_inverted_index.identification, | 147 |
| abstract_inverted_index.transplantation | 13 |
| abstract_inverted_index.immunophenotypes | 88 |
| cited_by_percentile_year.max | 96 |
| cited_by_percentile_year.min | 94 |
| corresponding_author_ids | https://openalex.org/A5087245622 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 6 |
| corresponding_institution_ids | https://openalex.org/I4210102412 |
| citation_normalized_percentile.value | 0.57582181 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |