External dose assessment from the patients treated by 177Lu-DOTATATE Article Swipe
Ebrahim Mahmoudi
,
Mahasti Amoui
,
Mohammad Reza Deevband
,
Elahe Pirayesh
,
Mehrdad Ghorbani Rad
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.52547/ijrr.20.1.36
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.52547/ijrr.20.1.36
Background: The present study was done to establish release criterion in the treated patients and to determine external radiation doses received by personnel and caregivers of patients with metastatic neuroendocrine tumors (NETs) during peptide receptor radionuclide therapy (PRRT) by means of Lutetium-177 (177Lu) DOTATATE. Materials and Methods: For this purpose, 30 patients were enrolled in the study who received 5.5±1.1 (in a range of: 3.7-7.4) GBq of 177Lu-DOTA-tyr3-octreotate. Dose rate was analyzed at distances 0, 0.25, 0.5, 1.0, and 2.0 m in different times after termination of infusion using an ionization chamber. Results: Mean dose rate at distance of 1 m from the patient, approximately 5 h after injection was considered as discharge limit. The maximum dose to caregivers in the first 48 h was equal to 340±29 μSv. Mean dose to the nurse was estimated as 6.3±0.4, and 7±0.5 µSv per patient with and without lead shield, respectively. Discussion: According to our findings, approximately a time delay of 5 h after injection is recommended as release criterion for patients treated by Lutetium-177 (177Lu) DOTATATE. For a total of 30 patients, external radiation dose to staff was found to be within permissible levels. Conclusion: The use of protective equipment is recommended at all stages of procedure for staff.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.52547/ijrr.20.1.36
- http://ijrr.com/files/site1/user_files_fad21f/s_babaloui-A-10-2188-88-563a684.pdf
- OA Status
- diamond
- Cited By
- 1
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4285168083
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4285168083Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.52547/ijrr.20.1.36Digital Object Identifier
- Title
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External dose assessment from the patients treated by 177Lu-DOTATATEWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-01-01Full publication date if available
- Authors
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Ebrahim Mahmoudi, Mahasti Amoui, Mohammad Reza Deevband, Elahe Pirayesh, Mehrdad Ghorbani RadList of authors in order
- Landing page
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https://doi.org/10.52547/ijrr.20.1.36Publisher landing page
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https://ijrr.com/files/site1/user_files_fad21f/s_babaloui-A-10-2188-88-563a684.pdfDirect link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://ijrr.com/files/site1/user_files_fad21f/s_babaloui-A-10-2188-88-563a684.pdfDirect OA link when available
- Concepts
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Radionuclide therapy, Medicine, Nuclear medicine, Dose rate, Neuroendocrine tumors, Lutetium, Internal medicine, Medical physics, Chemistry, Organic chemistry, Oxide, YttriumTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1Per-year citation counts (last 5 years)
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.done | 5 |
| abstract_inverted_index.dose | 94, 116, 130, 183 |
| abstract_inverted_index.from | 101 |
| abstract_inverted_index.lead | 146 |
| abstract_inverted_index.rate | 69, 95 |
| abstract_inverted_index.this | 48 |
| abstract_inverted_index.time | 156 |
| abstract_inverted_index.were | 52 |
| abstract_inverted_index.with | 27, 143 |
| abstract_inverted_index.µSv | 140 |
| abstract_inverted_index.0.25, | 75 |
| abstract_inverted_index.after | 84, 107, 161 |
| abstract_inverted_index.delay | 157 |
| abstract_inverted_index.doses | 19 |
| abstract_inverted_index.equal | 125 |
| abstract_inverted_index.first | 121 |
| abstract_inverted_index.found | 187 |
| abstract_inverted_index.means | 39 |
| abstract_inverted_index.nurse | 133 |
| abstract_inverted_index.range | 62 |
| abstract_inverted_index.staff | 185 |
| abstract_inverted_index.study | 3, 56 |
| abstract_inverted_index.times | 83 |
| abstract_inverted_index.total | 177 |
| abstract_inverted_index.using | 88 |
| abstract_inverted_index.μSv. | 128 |
| abstract_inverted_index.(NETs) | 31 |
| abstract_inverted_index.(PRRT) | 37 |
| abstract_inverted_index.7±0.5 | 139 |
| abstract_inverted_index.during | 32 |
| abstract_inverted_index.limit. | 113 |
| abstract_inverted_index.staff. | 207 |
| abstract_inverted_index.stages | 203 |
| abstract_inverted_index.tumors | 30 |
| abstract_inverted_index.within | 190 |
| abstract_inverted_index.(177Lu) | 42, 173 |
| abstract_inverted_index.340±29 | 127 |
| abstract_inverted_index.levels. | 192 |
| abstract_inverted_index.maximum | 115 |
| abstract_inverted_index.patient | 142 |
| abstract_inverted_index.peptide | 33 |
| abstract_inverted_index.present | 2 |
| abstract_inverted_index.release | 8, 166 |
| abstract_inverted_index.shield, | 147 |
| abstract_inverted_index.therapy | 36 |
| abstract_inverted_index.treated | 12, 170 |
| abstract_inverted_index.without | 145 |
| abstract_inverted_index.3.7-7.4) | 64 |
| abstract_inverted_index.5.5±1.1 | 59 |
| abstract_inverted_index.Methods: | 46 |
| abstract_inverted_index.Results: | 92 |
| abstract_inverted_index.analyzed | 71 |
| abstract_inverted_index.chamber. | 91 |
| abstract_inverted_index.distance | 97 |
| abstract_inverted_index.enrolled | 53 |
| abstract_inverted_index.external | 17, 181 |
| abstract_inverted_index.infusion | 87 |
| abstract_inverted_index.patient, | 103 |
| abstract_inverted_index.patients | 13, 26, 51, 169 |
| abstract_inverted_index.purpose, | 49 |
| abstract_inverted_index.received | 20, 58 |
| abstract_inverted_index.receptor | 34 |
| abstract_inverted_index.6.3±0.4, | 137 |
| abstract_inverted_index.According | 150 |
| abstract_inverted_index.DOTATATE. | 43, 174 |
| abstract_inverted_index.Materials | 44 |
| abstract_inverted_index.criterion | 9, 167 |
| abstract_inverted_index.determine | 16 |
| abstract_inverted_index.different | 82 |
| abstract_inverted_index.discharge | 112 |
| abstract_inverted_index.distances | 73 |
| abstract_inverted_index.equipment | 198 |
| abstract_inverted_index.establish | 7 |
| abstract_inverted_index.estimated | 135 |
| abstract_inverted_index.findings, | 153 |
| abstract_inverted_index.injection | 108, 162 |
| abstract_inverted_index.patients, | 180 |
| abstract_inverted_index.personnel | 22 |
| abstract_inverted_index.procedure | 205 |
| abstract_inverted_index.radiation | 18, 182 |
| abstract_inverted_index.caregivers | 24, 118 |
| abstract_inverted_index.considered | 110 |
| abstract_inverted_index.ionization | 90 |
| abstract_inverted_index.metastatic | 28 |
| abstract_inverted_index.protective | 197 |
| abstract_inverted_index.Background: | 0 |
| abstract_inverted_index.Conclusion: | 193 |
| abstract_inverted_index.Discussion: | 149 |
| abstract_inverted_index.permissible | 191 |
| abstract_inverted_index.recommended | 164, 200 |
| abstract_inverted_index.termination | 85 |
| abstract_inverted_index.Lutetium-177 | 41, 172 |
| abstract_inverted_index.radionuclide | 35 |
| abstract_inverted_index.approximately | 104, 154 |
| abstract_inverted_index.respectively. | 148 |
| abstract_inverted_index.neuroendocrine | 29 |
| abstract_inverted_index.177Lu-DOTA-tyr3-octreotate. | 67 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.6299999952316284 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.46895145 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |