Extracellular vesicles derived from hypoxic HTR-8/SVneo trophoblast inhibit endothelial cell functions through the miR-150-3p /CHPF pathway Article Swipe
Menghan Sha
,
Shunran Zhang
,
Rajluxmee Beejadhursing
,
Yanan Sun
,
Qin Yu
,
Suhua Chen
,
Wei Li
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1016/j.placenta.2023.04.017
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1016/j.placenta.2023.04.017
Our findings indicate that extracellular vesicles miR-150-3p derived from hypoxic trophoblasts inhibits endothelial cells proliferation, migration, and angiogenesis by modulating CHPF, illuminating a novel mechanism of hypoxic trophoblasts regulation of endothelial cells and their potential role in PE pathogenesis.
Related Topics
Concepts
Angiogenesis
Cell biology
Trophoblast
Endothelial stem cell
Biology
Microvesicles
microRNA
Vascular endothelial growth factor A
Extracellular
Vascular endothelial growth factor
Cancer research
Placenta
Biochemistry
Gene
In vitro
Fetus
Genetics
VEGF receptors
Pregnancy
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.placenta.2023.04.017
- OA Status
- hybrid
- Cited By
- 7
- References
- 52
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4367673843
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4367673843Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1016/j.placenta.2023.04.017Digital Object Identifier
- Title
-
Extracellular vesicles derived from hypoxic HTR-8/SVneo trophoblast inhibit endothelial cell functions through the miR-150-3p /CHPF pathwayWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-05-02Full publication date if available
- Authors
-
Menghan Sha, Shunran Zhang, Rajluxmee Beejadhursing, Yanan Sun, Qin Yu, Suhua Chen, Wei LiList of authors in order
- Landing page
-
https://doi.org/10.1016/j.placenta.2023.04.017Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1016/j.placenta.2023.04.017Direct OA link when available
- Concepts
-
Angiogenesis, Cell biology, Trophoblast, Endothelial stem cell, Biology, Microvesicles, microRNA, Vascular endothelial growth factor A, Extracellular, Vascular endothelial growth factor, Cancer research, Placenta, Biochemistry, Gene, In vitro, Fetus, Genetics, VEGF receptors, PregnancyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
7Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3, 2024: 4Per-year citation counts (last 5 years)
- References (count)
-
52Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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