Fabrication and evaluation of CMC-Ag and CMC-Zn-based composite films as biobased wound dressings Article Swipe
Maham Fatima
,
Yasir Iqbal
,
Muhammad Muneeb Ahmad
,
Shahzad Ali Shahid Chatha
,
Ikram Ullah Khan
,
Abdullah Ijaz Hussain
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1016/j.carpta.2024.100476
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1016/j.carpta.2024.100476
This work aims to enhance the efficiency and properties of carboxymethyl cellulose (CMC) by introducing silver and zinc ions. CMC incorporated with a silver (CMC-Ag) and CMC incorporated with zinc (CMC-Zn) composites and films were prepared, characterized and evaluated for biological activities respectively. The CMC-Ag and CMC-Zn composites and composite films showed notable antibacterial and antioxidant activities based on increasing Ag and Zn concentrations. The CMC-Ag composite films displayed the highest wound contraction 89.79% followed by CMC-Zn composite films 89.24% on the 10th day with low levels of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α). Histological images of wounds treated with these composite films exhibited healed epidermis and a clear view of collagen deposition. These findings demonstrate that our prepared composite films have auspicious features with eloquent antibacterial, antioxidant and wound-healing properties which could be used as biobased wound dressings.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.carpta.2024.100476
- OA Status
- gold
- Cited By
- 7
- References
- 71
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4392454545Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.carpta.2024.100476Digital Object Identifier
- Title
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Fabrication and evaluation of CMC-Ag and CMC-Zn-based composite films as biobased wound dressingsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-03-05Full publication date if available
- Authors
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Maham Fatima, Yasir Iqbal, Muhammad Muneeb Ahmad, Shahzad Ali Shahid Chatha, Ikram Ullah Khan, Abdullah Ijaz HussainList of authors in order
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https://doi.org/10.1016/j.carpta.2024.100476Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1016/j.carpta.2024.100476Direct OA link when available
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Fabrication, Composite number, Materials science, Composite material, Wound dressing, Composite film, Chemical engineering, Polymer science, Engineering, Medicine, Pathology, Alternative medicineTop concepts (fields/topics) attached by OpenAlex
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7Total citation count in OpenAlex
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2025: 7Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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| primary_location.raw_source_name | Carbohydrate Polymer Technologies and Applications |
| primary_location.landing_page_url | https://doi.org/10.1016/j.carpta.2024.100476 |
| publication_date | 2024-03-05 |
| publication_year | 2024 |
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