Fabrication of a Urea Biosensor for Real-Time Dynamic Fluid Measurement Article Swipe
Related Concepts
Biosensor
Fabrication
Urea
Computer science
Nanotechnology
Materials science
Embedded system
Chemistry
Organic chemistry
Alternative medicine
Pathology
Medicine
Kyung‐Hee Kim
,
J. Lee
,
Bo Mi Moon
,
Ye Been Seo
,
Chan Hum Park
,
Min Park
,
Gun Yong Sung
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3390/s18082607
· OA: W2885992665
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3390/s18082607
· OA: W2885992665
In this study, a portable urea sensor that monitors the urea concentration in flow conditions was fabricated. We propose an electrochemical sensor that continually measures the urea concentration of samples flowing through it at a constant flow rate in real time. For the electrochemical sensing, a porous silk fibroin membrane with immobilized urease was mounted in a polydimethylsiloxane (PDMS) sensor housing. The fabricated urea sensor elicited linear current–concentration characteristics in the clinically significant concentration range (0.1–20 mM) based on peritoneal dialysis. The sensor maintained the linear current–concentration characteristics during operation in flow conditions.
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