Facilitate integrated analysis of single cell multiomic data by binarizing gene expression values Article Swipe
Rohan Misra
,
Alexander Ferrena
,
Deyou Zheng
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1038/s41467-025-60899-8
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1038/s41467-025-60899-8
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1038/s41467-025-60899-8
- https://www.nature.com/articles/s41467-025-60899-8.pdf
- OA Status
- gold
- Cited By
- 1
- References
- 43
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4411886636
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4411886636Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1038/s41467-025-60899-8Digital Object Identifier
- Title
-
Facilitate integrated analysis of single cell multiomic data by binarizing gene expression valuesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-07-01Full publication date if available
- Authors
-
Rohan Misra, Alexander Ferrena, Deyou ZhengList of authors in order
- Landing page
-
https://doi.org/10.1038/s41467-025-60899-8Publisher landing page
- PDF URL
-
https://www.nature.com/articles/s41467-025-60899-8.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.nature.com/articles/s41467-025-60899-8.pdfDirect OA link when available
- Concepts
-
Gene, Expression (computer science), Gene expression, Computational biology, Computer science, Cell, Cell biology, Biology, Genetics, Programming languageTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1Per-year citation counts (last 5 years)
- References (count)
-
43Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4411886636 |
|---|---|
| doi | https://doi.org/10.1038/s41467-025-60899-8 |
| ids.doi | https://doi.org/10.1038/s41467-025-60899-8 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40595539 |
| ids.openalex | https://openalex.org/W4411886636 |
| fwci | 2.68294463 |
| mesh[0].qualifier_ui | Q000379 |
| mesh[0].descriptor_ui | D059010 |
| mesh[0].is_major_topic | True |
| mesh[0].qualifier_name | methods |
| mesh[0].descriptor_name | Single-Cell Analysis |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D000465 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Algorithms |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D006801 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Humans |
| mesh[3].qualifier_ui | Q000379 |
| mesh[3].descriptor_ui | D020869 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | methods |
| mesh[3].descriptor_name | Gene Expression Profiling |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D016000 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Cluster Analysis |
| mesh[5].qualifier_ui | Q000235 |
| mesh[5].descriptor_ui | D059467 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | genetics |
| mesh[5].descriptor_name | Transcriptome |
| mesh[6].qualifier_ui | Q000379 |
| mesh[6].descriptor_ui | D000081246 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | methods |
| mesh[6].descriptor_name | RNA-Seq |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D000818 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Animals |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D051379 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Mice |
| mesh[9].qualifier_ui | Q000379 |
| mesh[9].descriptor_ui | D017423 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | methods |
| mesh[9].descriptor_name | Sequence Analysis, RNA |
| mesh[10].qualifier_ui | Q000379 |
| mesh[10].descriptor_ui | D059010 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | methods |
| mesh[10].descriptor_name | Single-Cell Analysis |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D000465 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Algorithms |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D006801 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Humans |
| mesh[13].qualifier_ui | Q000379 |
| mesh[13].descriptor_ui | D020869 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | methods |
| mesh[13].descriptor_name | Gene Expression Profiling |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D016000 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Cluster Analysis |
| mesh[15].qualifier_ui | Q000235 |
| mesh[15].descriptor_ui | D059467 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | genetics |
| mesh[15].descriptor_name | Transcriptome |
| mesh[16].qualifier_ui | Q000379 |
| mesh[16].descriptor_ui | D000081246 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | methods |
| mesh[16].descriptor_name | RNA-Seq |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D000818 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Animals |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D051379 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Mice |
| mesh[19].qualifier_ui | Q000379 |
| mesh[19].descriptor_ui | D017423 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | methods |
| mesh[19].descriptor_name | Sequence Analysis, RNA |
| mesh[20].qualifier_ui | Q000379 |
| mesh[20].descriptor_ui | D059010 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | methods |
| mesh[20].descriptor_name | Single-Cell Analysis |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D000465 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Algorithms |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D006801 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Humans |
| mesh[23].qualifier_ui | Q000379 |
| mesh[23].descriptor_ui | D020869 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | methods |
| mesh[23].descriptor_name | Gene Expression Profiling |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D016000 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Cluster Analysis |
| mesh[25].qualifier_ui | Q000235 |
| mesh[25].descriptor_ui | D059467 |
| mesh[25].is_major_topic | True |
| mesh[25].qualifier_name | genetics |
| mesh[25].descriptor_name | Transcriptome |
| mesh[26].qualifier_ui | Q000379 |
| mesh[26].descriptor_ui | D000081246 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | methods |
| mesh[26].descriptor_name | RNA-Seq |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D000818 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Animals |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D051379 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Mice |
| mesh[29].qualifier_ui | Q000379 |
| mesh[29].descriptor_ui | D017423 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | methods |
| mesh[29].descriptor_name | Sequence Analysis, RNA |
| mesh[30].qualifier_ui | Q000379 |
| mesh[30].descriptor_ui | D059010 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | methods |
| mesh[30].descriptor_name | Single-Cell Analysis |
| mesh[31].qualifier_ui | |
| mesh[31].descriptor_ui | D000465 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | |
| mesh[31].descriptor_name | Algorithms |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D006801 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Humans |
| mesh[33].qualifier_ui | Q000379 |
| mesh[33].descriptor_ui | D020869 |
| mesh[33].is_major_topic | True |
| mesh[33].qualifier_name | methods |
| mesh[33].descriptor_name | Gene Expression Profiling |
| mesh[34].qualifier_ui | |
| mesh[34].descriptor_ui | D016000 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | |
| mesh[34].descriptor_name | Cluster Analysis |
| mesh[35].qualifier_ui | Q000235 |
| mesh[35].descriptor_ui | D059467 |
| mesh[35].is_major_topic | True |
| mesh[35].qualifier_name | genetics |
| mesh[35].descriptor_name | Transcriptome |
| mesh[36].qualifier_ui | Q000379 |
| mesh[36].descriptor_ui | D000081246 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | methods |
| mesh[36].descriptor_name | RNA-Seq |
| mesh[37].qualifier_ui | |
| mesh[37].descriptor_ui | D000818 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | |
| mesh[37].descriptor_name | Animals |
| mesh[38].qualifier_ui | |
| mesh[38].descriptor_ui | D051379 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | |
| mesh[38].descriptor_name | Mice |
| mesh[39].qualifier_ui | Q000379 |
| mesh[39].descriptor_ui | D017423 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | methods |
| mesh[39].descriptor_name | Sequence Analysis, RNA |
| type | article |
| title | Facilitate integrated analysis of single cell multiomic data by binarizing gene expression values |
| awards[0].id | https://openalex.org/G7577253276 |
| awards[0].funder_id | https://openalex.org/F4320337338 |
| awards[0].display_name | |
| awards[0].funder_award_id | R01HL163667 |
| awards[0].funder_display_name | National Heart, Lung, and Blood Institute |
| awards[1].id | https://openalex.org/G933209776 |
| awards[1].funder_id | https://openalex.org/F4320337338 |
| awards[1].display_name | |
| awards[1].funder_award_id | R01HL153920 |
| awards[1].funder_display_name | National Heart, Lung, and Blood Institute |
| awards[2].id | https://openalex.org/G1228145371 |
| awards[2].funder_id | https://openalex.org/F4320337611 |
| awards[2].display_name | |
| awards[2].funder_award_id | P50HD105352 |
| awards[2].funder_display_name | Eunice Kennedy Shriver National Institute of Child Health and Human Development |
| biblio.issue | 1 |
| biblio.volume | 16 |
| biblio.last_page | 5763 |
| biblio.first_page | 5763 |
| topics[0].id | https://openalex.org/T11289 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | Single-cell and spatial transcriptomics |
| topics[1].id | https://openalex.org/T10885 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9761999845504761 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | Gene expression and cancer classification |
| topics[2].id | https://openalex.org/T10621 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9225999712944031 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | Gene Regulatory Network Analysis |
| funders[0].id | https://openalex.org/F4320337338 |
| funders[0].ror | https://ror.org/012pb6c26 |
| funders[0].display_name | National Heart, Lung, and Blood Institute |
| funders[1].id | https://openalex.org/F4320337611 |
| funders[1].ror | https://ror.org/04byxyr05 |
| funders[1].display_name | Eunice Kennedy Shriver National Institute of Child Health and Human Development |
| is_xpac | False |
| apc_list.value | 3920 |
| apc_list.currency | GBP |
| apc_list.value_usd | 4808 |
| apc_paid.value | 3920 |
| apc_paid.currency | GBP |
| apc_paid.value_usd | 4808 |
| concepts[0].id | https://openalex.org/C104317684 |
| concepts[0].level | 2 |
| concepts[0].score | 0.5548047423362732 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[0].display_name | Gene |
| concepts[1].id | https://openalex.org/C90559484 |
| concepts[1].level | 2 |
| concepts[1].score | 0.5485379099845886 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q778379 |
| concepts[1].display_name | Expression (computer science) |
| concepts[2].id | https://openalex.org/C150194340 |
| concepts[2].level | 3 |
| concepts[2].score | 0.5432040691375732 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q26972 |
| concepts[2].display_name | Gene expression |
| concepts[3].id | https://openalex.org/C70721500 |
| concepts[3].level | 1 |
| concepts[3].score | 0.49127334356307983 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q177005 |
| concepts[3].display_name | Computational biology |
| concepts[4].id | https://openalex.org/C41008148 |
| concepts[4].level | 0 |
| concepts[4].score | 0.4843927025794983 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[4].display_name | Computer science |
| concepts[5].id | https://openalex.org/C1491633281 |
| concepts[5].level | 2 |
| concepts[5].score | 0.4120125472545624 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q7868 |
| concepts[5].display_name | Cell |
| concepts[6].id | https://openalex.org/C95444343 |
| concepts[6].level | 1 |
| concepts[6].score | 0.38661623001098633 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q7141 |
| concepts[6].display_name | Cell biology |
| concepts[7].id | https://openalex.org/C86803240 |
| concepts[7].level | 0 |
| concepts[7].score | 0.3855036497116089 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[7].display_name | Biology |
| concepts[8].id | https://openalex.org/C54355233 |
| concepts[8].level | 1 |
| concepts[8].score | 0.3622676432132721 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[8].display_name | Genetics |
| concepts[9].id | https://openalex.org/C199360897 |
| concepts[9].level | 1 |
| concepts[9].score | 0.0 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q9143 |
| concepts[9].display_name | Programming language |
| keywords[0].id | https://openalex.org/keywords/gene |
| keywords[0].score | 0.5548047423362732 |
| keywords[0].display_name | Gene |
| keywords[1].id | https://openalex.org/keywords/expression |
| keywords[1].score | 0.5485379099845886 |
| keywords[1].display_name | Expression (computer science) |
| keywords[2].id | https://openalex.org/keywords/gene-expression |
| keywords[2].score | 0.5432040691375732 |
| keywords[2].display_name | Gene expression |
| keywords[3].id | https://openalex.org/keywords/computational-biology |
| keywords[3].score | 0.49127334356307983 |
| keywords[3].display_name | Computational biology |
| keywords[4].id | https://openalex.org/keywords/computer-science |
| keywords[4].score | 0.4843927025794983 |
| keywords[4].display_name | Computer science |
| keywords[5].id | https://openalex.org/keywords/cell |
| keywords[5].score | 0.4120125472545624 |
| keywords[5].display_name | Cell |
| keywords[6].id | https://openalex.org/keywords/cell-biology |
| keywords[6].score | 0.38661623001098633 |
| keywords[6].display_name | Cell biology |
| keywords[7].id | https://openalex.org/keywords/biology |
| keywords[7].score | 0.3855036497116089 |
| keywords[7].display_name | Biology |
| keywords[8].id | https://openalex.org/keywords/genetics |
| keywords[8].score | 0.3622676432132721 |
| keywords[8].display_name | Genetics |
| language | en |
| locations[0].id | doi:10.1038/s41467-025-60899-8 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S64187185 |
| locations[0].source.issn | 2041-1723 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2041-1723 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Nature Communications |
| locations[0].source.host_organization | https://openalex.org/P4310319908 |
| locations[0].source.host_organization_name | Nature Portfolio |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310319908, https://openalex.org/P4310319965 |
| locations[0].source.host_organization_lineage_names | Nature Portfolio, Springer Nature |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | https://www.nature.com/articles/s41467-025-60899-8.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Nature Communications |
| locations[0].landing_page_url | https://doi.org/10.1038/s41467-025-60899-8 |
| locations[1].id | pmid:40595539 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Nature communications |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40595539 |
| locations[2].id | pmh:oai:doaj.org/article:1dc18daeddb04e91ac3192364b798f4d |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Nature Communications, Vol 16, Iss 1, Pp 1-12 (2025) |
| locations[2].landing_page_url | https://doaj.org/article/1dc18daeddb04e91ac3192364b798f4d |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:12218346 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Nat Commun |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/12218346 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5040737138 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-6355-2764 |
| authorships[0].author.display_name | Rohan Misra |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I129975664 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. |
| authorships[0].institutions[0].id | https://openalex.org/I129975664 |
| authorships[0].institutions[0].ror | https://ror.org/05cf8a891 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I129975664, https://openalex.org/I4210112371 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Albert Einstein College of Medicine |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Rohan Misra |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. |
| authorships[1].author.id | https://openalex.org/A5075967282 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-9578-8683 |
| authorships[1].author.display_name | Alexander Ferrena |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I129975664 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I129975664 |
| authorships[1].affiliations[1].raw_affiliation_string | Institute for Clinical and Translational Research, Albert Einstein College of Medicine, Bronx, NY, USA. |
| authorships[1].institutions[0].id | https://openalex.org/I129975664 |
| authorships[1].institutions[0].ror | https://ror.org/05cf8a891 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I129975664, https://openalex.org/I4210112371 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Albert Einstein College of Medicine |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Alexander Ferrena |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA., Institute for Clinical and Translational Research, Albert Einstein College of Medicine, Bronx, NY, USA. |
| authorships[2].author.id | https://openalex.org/A5053246999 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-4354-5337 |
| authorships[2].author.display_name | Deyou Zheng |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I129975664 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]. |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I129975664 |
| authorships[2].affiliations[1].raw_affiliation_string | Data Science Institute, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]. |
| authorships[2].affiliations[2].institution_ids | https://openalex.org/I129975664 |
| authorships[2].affiliations[2].raw_affiliation_string | Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]. |
| authorships[2].affiliations[3].institution_ids | https://openalex.org/I129975664 |
| authorships[2].affiliations[3].raw_affiliation_string | Marilyn and Stanley M. Katz Institute for Immunotherapy for Cancer and Inflammatory Disorders, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]. |
| authorships[2].affiliations[4].institution_ids | https://openalex.org/I129975664 |
| authorships[2].affiliations[4].raw_affiliation_string | Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]. |
| authorships[2].institutions[0].id | https://openalex.org/I129975664 |
| authorships[2].institutions[0].ror | https://ror.org/05cf8a891 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I129975664, https://openalex.org/I4210112371 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Albert Einstein College of Medicine |
| authorships[2].author_position | last |
| authorships[2].raw_author_name | Deyou Zheng |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Data Science Institute, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]., Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]., Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]., Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]., Marilyn and Stanley M. Katz Institute for Immunotherapy for Cancer and Inflammatory Disorders, Albert Einstein College of Medicine, Bronx, NY, USA. [email protected]. |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.nature.com/articles/s41467-025-60899-8.pdf |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Facilitate integrated analysis of single cell multiomic data by binarizing gene expression values |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11289 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | Single-cell and spatial transcriptomics |
| related_works | https://openalex.org/W2392243736, https://openalex.org/W86652014, https://openalex.org/W2328518092, https://openalex.org/W3101249758, https://openalex.org/W2382079200, https://openalex.org/W2803323662, https://openalex.org/W3032874291, https://openalex.org/W2005057264, https://openalex.org/W2363156284, https://openalex.org/W2415025170 |
| cited_by_count | 1 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1038/s41467-025-60899-8 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S64187185 |
| best_oa_location.source.issn | 2041-1723 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2041-1723 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Nature Communications |
| best_oa_location.source.host_organization | https://openalex.org/P4310319908 |
| best_oa_location.source.host_organization_name | Nature Portfolio |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310319908, https://openalex.org/P4310319965 |
| best_oa_location.source.host_organization_lineage_names | Nature Portfolio, Springer Nature |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | https://www.nature.com/articles/s41467-025-60899-8.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Nature Communications |
| best_oa_location.landing_page_url | https://doi.org/10.1038/s41467-025-60899-8 |
| primary_location.id | doi:10.1038/s41467-025-60899-8 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S64187185 |
| primary_location.source.issn | 2041-1723 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2041-1723 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Nature Communications |
| primary_location.source.host_organization | https://openalex.org/P4310319908 |
| primary_location.source.host_organization_name | Nature Portfolio |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310319908, https://openalex.org/P4310319965 |
| primary_location.source.host_organization_lineage_names | Nature Portfolio, Springer Nature |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | https://www.nature.com/articles/s41467-025-60899-8.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Nature Communications |
| primary_location.landing_page_url | https://doi.org/10.1038/s41467-025-60899-8 |
| publication_date | 2025-07-01 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W1988391018, https://openalex.org/W4362521490, https://openalex.org/W2912390237, https://openalex.org/W2887910040, https://openalex.org/W3131634425, https://openalex.org/W3195317458, https://openalex.org/W3049084893, https://openalex.org/W4312182122, https://openalex.org/W2972926980, https://openalex.org/W3009609875, https://openalex.org/W4200035191, https://openalex.org/W2136453810, https://openalex.org/W4389202278, https://openalex.org/W2887766567, https://openalex.org/W2800392236, https://openalex.org/W3164692211, https://openalex.org/W2523369352, https://openalex.org/W1492083415, https://openalex.org/W2967177832, https://openalex.org/W3088401235, https://openalex.org/W4378212544, https://openalex.org/W3210860076, https://openalex.org/W3159800610, https://openalex.org/W4409523068, https://openalex.org/W4317884487, https://openalex.org/W2808845633, https://openalex.org/W1987971958, https://openalex.org/W4235169531, https://openalex.org/W2626120438, https://openalex.org/W4306956360, https://openalex.org/W4387568481, https://openalex.org/W4366606312, https://openalex.org/W4313527389, https://openalex.org/W2897249806, https://openalex.org/W2997280954, https://openalex.org/W4210607772, https://openalex.org/W4362737480, https://openalex.org/W2946721812, https://openalex.org/W6675354045, https://openalex.org/W2030644393, https://openalex.org/W4220668517, https://openalex.org/W6893394492, https://openalex.org/W3106188259 |
| referenced_works_count | 43 |
| abstract_inverted_index | |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 3 |
| citation_normalized_percentile.value | 0.82238451 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |