Factors influencing adherence to antiretroviral therapy from the experience of people living with HIV and their healthcare providers in Sierra Leone: A qualitative study Article Swipe
Michael Lahai
,
Sally Theobald
,
Haja R. Wurie
,
Sulaiman Lakoh
,
Mohamed Samai
,
Patrick O. Erah
,
Joanna Raven
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-1358803/v1
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-1358803/v1
Background: Antiretroviral therapy is the main drug for the treatment of Human Immunodeficiency Virus, slow disease progression, and reduce the spread of infection. HIV treatment is also known to require high level of adherence of over 90% to achieve good treatment outcomes and viral load suppression. In Sierra Leone, it is estimated that about 70% of PLHIV are non-adherent in their first year of treatment. Understanding the reasons behind this high-rate of non-adherence is critical for the development of strategies to improve adherence. This study identifies the barriers and facilitators influencing adherence to antiretroviral treatment in Sierra Leone. Methods: A qualitative study design using in depth interviews was conducted in two districts in Sierra Leone – Freetown and Bo. In-depth interviews were conducted with 4 health care workers and 16 people living with HIV. Results: Several facilitators and barriers to Antiretroviral therapy(ART) adherence at the personal, community, and health system levels were identified. The facilitating factors included perceived benefits of ART, family support, having a treatment partner, receiving free ART medicines and belonging to peer support groups. The barriers included denial and non-disclosure of HIV status, frequency of medication, use of traditional medicine, lack of money for food and transport, stigma and discrimination, work barriers, lack of medicines and test kits, limited health workers and long distance to clinics. Conclusions: The key emerging themes arising from different health system level in this study include Support from families, treatment partners and the need for peer support groups. Understanding the facilitators and barriers to antiretroviral therapy identified in this study can improve adherence and provide relevant information for more responsive and equitable program implementation in low and middle-income countries. There is the need for implementing adherence augmentation programs with implementation of activities that will improve community knowledge for prevention and reduction of stigma and the need for integrating HIV treatment services close to communities.
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- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-1358803/v1
- https://www.researchsquare.com/article/rs-1358803/latest.pdf
- OA Status
- green
- Cited By
- 1
- References
- 25
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4221040150
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4221040150Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.21203/rs.3.rs-1358803/v1Digital Object Identifier
- Title
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Factors influencing adherence to antiretroviral therapy from the experience of people living with HIV and their healthcare providers in Sierra Leone: A qualitative studyWork title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-03-28Full publication date if available
- Authors
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Michael Lahai, Sally Theobald, Haja R. Wurie, Sulaiman Lakoh, Mohamed Samai, Patrick O. Erah, Joanna RavenList of authors in order
- Landing page
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https://doi.org/10.21203/rs.3.rs-1358803/v1Publisher landing page
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https://www.researchsquare.com/article/rs-1358803/latest.pdfDirect link to full text PDF
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://www.researchsquare.com/article/rs-1358803/latest.pdfDirect OA link when available
- Concepts
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Sierra leone, Qualitative research, Medicine, Stigma (botany), Denial, Family medicine, Health care, Antiretroviral therapy, Nursing, Human immunodeficiency virus (HIV), Viral load, Psychology, Psychiatry, Socioeconomics, Psychoanalysis, Social science, Economic growth, Sociology, EconomicsTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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