Family influences on oral PrEP use among adolescent girls and young women in Kenya and South Africa Article Swipe
YOU?
·
· 2023
· Open Access
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· DOI: https://doi.org/10.1371/journal.pone.0292529
Introduction Effective use of oral HIV pre-exposure prophylaxis (PrEP) has been lower among African adolescent girls and young women (AGYW) than among older women, young men who have sex with men, and serodiscordant heterosexual couples in the region. Efforts to build PrEP support have centered around peers and male partners, but the family may also play an important role. This qualitative study aimed to describe family influence on PrEP use among AGYW in in three African cities. Methods POWER (Prevention Options for Women Evaluation Research) was a PrEP demonstration project among 2550 AGYW (16–25 years old) in Johannesburg and Cape Town, South Africa and Kisumu, Kenya conducted from 2017 to 2020. In-depth interviews and focus group discussions were conducted with 136 AGYW participants to explore their PrEP views and experiences, including awareness and interest in PrEP; barriers and facilitators to uptake and use; the influence of family, peers, intimate partners, and community; and the key types of support for their PrEP use. Transcripts were coded and analysed thematically. Results The decision to initiate PrEP was associated with fear and anxiety linked to anticipated stigma from family members, and with family’s lived HIV experience. Family disclosure, especially to mothers, was important to participants, as most lived with their families and considered it essential for them to obtain their mother’s approval to use PrEP. Most family members, particularly mothers, provided instrumental, emotional, informational and appraisal support to participants using PrEP, including reminders, encouragement, and problem-solving. Participants reported that family members with insufficient information about PrEP safety and efficacy and who voiced concerns were a substantial barrier to their use. However, they often became supportive after receiving more PrEP information. Conclusion Families, particularly mothers, can play an important role in supporting PrEP use. PrEP programmes should leverage family support to help with PrEP persistence by providing basic information to families about PrEP safety and efficacy. AGYW using PrEP should be encouraged to selectively disclose PrEP use to build support and counseled on how to disclose and address family concerns.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1371/journal.pone.0292529
- https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0292529&type=printable
- OA Status
- gold
- Cited By
- 12
- References
- 39
- Related Works
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- OpenAlex ID
- https://openalex.org/W4388667869
Raw OpenAlex JSON
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https://openalex.org/W4388667869Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1371/journal.pone.0292529Digital Object Identifier
- Title
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Family influences on oral PrEP use among adolescent girls and young women in Kenya and South AfricaWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-11-14Full publication date if available
- Authors
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Makhosazane Nomhle Ndimande-Khoza, Ariana W. K. Katz, Sinead Moretlwe-Delany, Danielle Travill, Elzette Rousseau, Victor Omollo, Jennifer F. Morton, Rachel Johnson, Linda‐Gail Bekker, Elizabeth A. Bukusi, Jared M. Baeten, Connie Celum, Ariane van der Straten, Sarah T. RobertsList of authors in order
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https://doi.org/10.1371/journal.pone.0292529Publisher landing page
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0292529&type=printableDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0292529&type=printableDirect OA link when available
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Young adult, Medicine, Pediatrics, Demography, Gerontology, SociologyTop concepts (fields/topics) attached by OpenAlex
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12Total citation count in OpenAlex
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2025: 10, 2024: 2Per-year citation counts (last 5 years)
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39Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| corresponding_author_ids | https://openalex.org/A5006757078 |
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| corresponding_institution_ids | https://openalex.org/I192619145 |
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