Field Evaluation of a Ready-to-Use Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Vaccine in Naturally Infected Farms in Taiwan Article Swipe
Fu‐Chun Hsueh
,
Chi‐Hsien Chien
,
Shu‐Wei Chang
,
Bin Lian
,
Hongyao Lin
,
Leonardo Ellerma
,
Ming-Tang Chiou
,
Chao‐Nan Lin
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/vetsci12040304
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/vetsci12040304
Porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (MHP) are both important and common pathogens in the pig industry. Both pathogens are major contributors to the porcine respiratory disease complex and serve to potentiate other bacterial infections such as Actinobacillus pleuropneumonia. This study aims to evaluate the efficacy of a ready-to-use bivalent PCV2 and MHP vaccine in the field under naturally PCV2-infected farms against existing monovalent options. We evaluated PCV2 viremia, PCV2 antibodies, and lung lesion scores in slaughtered pigs in our study across four farms in Taiwan. Our results found that in two out of four farms, the piglets vaccinated with Porcilis® PCV M Hyo had superior whole-life PCV2 viremia reduction compared to the existing vaccination program on farms. In the lung lesion scoring, the Porcilis® PCV M Hyo group had significantly lower Actinobacillus pleuropneumonia-type lesions in pigs than in the competitor group in two out of three farms evaluated. In this field trial, Porcilis® PCV M Hyo proved to be efficacious in protecting piglets against both PCV2 viremia and the impact of MHP secondary infection, in the context of a reduction in viremia and reduced APP-like lesions found at slaughter.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/vetsci12040304
- https://www.mdpi.com/2306-7381/12/4/304/pdf?version=1743066371
- OA Status
- gold
- References
- 47
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4408928133
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4408928133Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/vetsci12040304Digital Object Identifier
- Title
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Field Evaluation of a Ready-to-Use Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Vaccine in Naturally Infected Farms in TaiwanWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-03-26Full publication date if available
- Authors
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Fu‐Chun Hsueh, Chi‐Hsien Chien, Shu‐Wei Chang, Bin Lian, Hongyao Lin, Leonardo Ellerma, Ming-Tang Chiou, Chao‐Nan LinList of authors in order
- Landing page
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https://doi.org/10.3390/vetsci12040304Publisher landing page
- PDF URL
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https://www.mdpi.com/2306-7381/12/4/304/pdf?version=1743066371Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2306-7381/12/4/304/pdf?version=1743066371Direct OA link when available
- Concepts
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Porcine circovirus, Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Viremia, Circovirus, Biology, Pleuropneumonia, Virology, Veterinary medicine, Medicine, Virus, SerotypeTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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47Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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