Figure S1 from RNA-encoded Interleukin 2 with Extended Bioavailability Amplifies RNA Vaccine–Induced Antitumor T-cell Immunity Article Swipe

View

Related Concepts

Immunity RNA Bioavailability Cell mediated immunity Biology Cell Immune system Chemistry Computational biology Immunology Gene Genetics Bioinformatics

Daniel Peters , Lena M. Kranz , David Eisel , Mustafa Diken , Sebastian Kreiter , Özlem Türeci , Uğur Şahin , Mathias Vormehr ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1158/2326-6066.28230870 · OA: W4406500955

<p>Mouse body weight in response to RNA-LPX and Alb-IL2 RNA-NP or rIL-2. Mouse total body weight after each of three weekly i.v. vaccinations with OVA RNA-LPX combined with one (1x) or five (5x) i.p. injections of rIL-2 or one i.v. injection of Alb-IL2 RNA-NP or Alb RNA-NP in C57BL/6 mice (n=7 mice/group) in per cent of initial mouse body weight. Mean + SEM. Vertical lines indicate treatments (dashed: OVA RNA-LPX + Alb RNA-NP, rIL-2 or Alb-IL2 RNA-NP; dotted: repetitive rIL-2).</p>