Figure S2 from Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis Article Swipe

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Amriti R. Lulla , Saïd Akli , Cansu Karakaş , Joseph A. Caruso , Lucas D. Warma , Natalie W. Fowlkes , Xiayu Rao , Jing Wang , Kelly K. Hunt , Stephanie S. Watowich , Khandan Keyomarsi ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.1158/1535-7163.25523454.v1

Supplementary Figure S2: (A) Percentage of tumor-free mice in PyMT NE+/+ (N=30) and PyMT NE-/- (N=21) mice, between 12-14 weeks of age. (B) Total tumor mass, (C) number of glands with tumors per mouse and (D) doubling time of tumors at end point (12-14 weeks age) in PyMT NE+/+ & PyMT NE-/- mice. (E) Frequency of the major histologies (solid, alveolar/tubular, papillary, and adenosquamous) detected in both PyMT NE+/+ and PyMT NE-/- primary tumors. (F) Spontaneous tumors isolated from PyMT NE+/+ and PyMT NE-/- mice were implanted in FVB NE+/+ and FVB NE-/- respectively. Tumor growth curves, as a function of days post implantation are shown.

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Neutrophil elastase Metastasis Lung Elastase Medicine Cancer research Immunology Biology Cancer Internal medicine Inflammation Enzyme Biochemistry

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/1535-7163.25523454.v1
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DOI: https://doi.org/10.1158/1535-7163.25523454.v1

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Title: Figure S2 from Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis

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Publication year: 2024

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Authors: Amriti R. Lulla, Saïd Akli, Cansu Karakaş, Joseph A. Caruso, Lucas D. Warma, Natalie W. Fowlkes, Xiayu Rao, Jing Wang, Kelly K. Hunt, Stephanie S. Watowich, Khandan Keyomarsi

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Concepts: Neutrophil elastase, Metastasis, Lung, Elastase, Medicine, Cancer research, Immunology, Biology, Cancer, Internal medicine, Inflammation, Enzyme, Biochemistry

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