Figures S1 to S8 from Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma Article Swipe

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Mohan S. Nandhu , Prajna Behera , Vivek Bhaskaran , Sharon L. Longo , Lina M. Barrera-Arenas , Sadhak Sengupta , Diego J. Rodriguez‐Gil , E. Antonio Chiocca , Mariano S. Viapiano ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1158/1078-0432.22464192

Figure S1: Generation of mAb428.2 antibody; Figure S2: Affinity of mAb428.2 for fibulin-3; Figure S3: mAb428.2 binds to cell-surface and interstitial fibulin-3; Figure S4: mAb428.2 does not cause acute toxicity; Figure S5: Locally-delivered mAb428.2 targets fibulin-3 signaling and tumor growth; Figure S6: IV-delivered mAb428.2 inhibits tumor growth; Figure S7: Effects of mAb428.2 against intracranial tumors; Figure S8: Biodistribution of mAb428.2 in naïve and tumor-bearing mice.

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Fibulin Cancer research Glioblastoma Antibody Function (biology) Blocking (statistics) Chemistry Molecular biology Medicine Biology Immunology Cell biology Biochemistry Gene Computer science Computer network

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Language: en
Landing Page: https://doi.org/10.1158/1078-0432.22464192
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DOI: https://doi.org/10.1158/1078-0432.22464192

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Title: Figures S1 to S8 from Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma

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Language: en

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Publication year: 2023

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Publication date: 2023-03-31

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Authors: Mohan S. Nandhu, Prajna Behera, Vivek Bhaskaran, Sharon L. Longo, Lina M. Barrera-Arenas, Sadhak Sengupta, Diego J. Rodriguez‐Gil, E. Antonio Chiocca, Mariano S. Viapiano

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Concepts: Fibulin, Cancer research, Glioblastoma, Antibody, Function (biology), Blocking (statistics), Chemistry, Molecular biology, Medicine, Biology, Immunology, Cell biology, Biochemistry, Gene, Computer science, Computer network

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