Free fat flap transfer in recurrent neurogenic thoracic outlet syndrome pain treatment: FIRST study Article Swipe
François Thuau
,
Guillaume Gadbled
,
Thomas Goronflot
,
Pierre Perrot
,
Alexandra Poinas
,
Ugo Lancien
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-5166504/v1
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-5166504/v1
Background: Neurogenic thoracic outlet syndrome (NTOS), characterized by brachial plexus compression, causes chronic pain and numbness in the upper extremities. Recurrences are common after surgical treatment, which typically includes an anterior scalenectomy and rib resection. Brachial plexus neurolysis and flap coverage can reduce scar fibrosis and prevent further recurrence. The latissimus dorsi flap is a common choice for this purpose. However, perforator fat flaps minimize donor site complications by avoiding muscle harvesting. Furthermore, a free flap transfer prevents new scars from developing in an already painful anatomical region. Given the lack of literature on this subject, we plan to use validated and recommended questionnaires to investigate the impact on pain and quality of life of brachial plexus wrapping with a free fat flap following neurolysis in cases of recurrent NTOS (R-NOS). Methods: FIRST is a single-center, prospective observational study recruiting participants over 24 months. Eligible patients over the age of 18 are treated with brachial plexus neurolysis and a free perforator fat flap for R-NTOS. The study aims to enroll 20 patients and involves preoperative and postoperative assessments at a six-month follow-up. The primary outcome, measured using numerical scales, is pain reduction. Secondary outcomes include decreased painful body surface area, maximum and average pain levels, changes in quality of life (QoL), upper limb function, and anxiety-depressive symptoms, which are measured using various validated scales and questionnaires. Discussion: The novelty of this study lies in its ability to provide information on the impact of free perforator fat flaps in R-NTOS treatment using validated, standardized and recommended methods of assessment for neuropathic pain, particularly considering the psychosocial impact.
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Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-5166504/v1
- https://www.researchsquare.com/article/rs-5166504/latest.pdf
- OA Status
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- References
- 21
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4404247985Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.21203/rs.3.rs-5166504/v1Digital Object Identifier
- Title
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Free fat flap transfer in recurrent neurogenic thoracic outlet syndrome pain treatment: FIRST studyWork title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-11-11Full publication date if available
- Authors
-
François Thuau, Guillaume Gadbled, Thomas Goronflot, Pierre Perrot, Alexandra Poinas, Ugo LancienList of authors in order
- Landing page
-
https://doi.org/10.21203/rs.3.rs-5166504/v1Publisher landing page
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https://www.researchsquare.com/article/rs-5166504/latest.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.researchsquare.com/article/rs-5166504/latest.pdfDirect OA link when available
- Concepts
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Medicine, Free flap, SurgeryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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21Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.Neurogenic | 2 |
| abstract_inverted_index.anatomical | 87 |
| abstract_inverted_index.assessment | 258 |
| abstract_inverted_index.developing | 82 |
| abstract_inverted_index.follow-up. | 182 |
| abstract_inverted_index.latissimus | 51 |
| abstract_inverted_index.literature | 93 |
| abstract_inverted_index.neurolysis | 38, 125, 157 |
| abstract_inverted_index.perforator | 62, 161, 245 |
| abstract_inverted_index.recruiting | 140 |
| abstract_inverted_index.reduction. | 192 |
| abstract_inverted_index.resection. | 35 |
| abstract_inverted_index.treatment, | 26 |
| abstract_inverted_index.validated, | 252 |
| abstract_inverted_index.Recurrences | 21 |
| abstract_inverted_index.assessments | 178 |
| abstract_inverted_index.considering | 263 |
| abstract_inverted_index.harvesting. | 72 |
| abstract_inverted_index.information | 239 |
| abstract_inverted_index.investigate | 106 |
| abstract_inverted_index.neuropathic | 260 |
| abstract_inverted_index.prospective | 137 |
| abstract_inverted_index.recommended | 103, 255 |
| abstract_inverted_index.recurrence. | 49 |
| abstract_inverted_index.Furthermore, | 73 |
| abstract_inverted_index.compression, | 11 |
| abstract_inverted_index.extremities. | 20 |
| abstract_inverted_index.participants | 141 |
| abstract_inverted_index.particularly | 262 |
| abstract_inverted_index.preoperative | 175 |
| abstract_inverted_index.psychosocial | 265 |
| abstract_inverted_index.scalenectomy | 32 |
| abstract_inverted_index.standardized | 253 |
| abstract_inverted_index.characterized | 7 |
| abstract_inverted_index.complications | 68 |
| abstract_inverted_index.observational | 138 |
| abstract_inverted_index.postoperative | 177 |
| abstract_inverted_index.questionnaires | 104 |
| abstract_inverted_index.single-center, | 136 |
| abstract_inverted_index.questionnaires. | 226 |
| abstract_inverted_index.anxiety-depressive | 216 |
| abstract_inverted_index.<bold>Methods:</bold> | 132 |
| abstract_inverted_index.<title>Abstract</title> | 0 |
| abstract_inverted_index.<bold>Background:</bold> | 1 |
| abstract_inverted_index.<bold>Discussion:</bold> | 227 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 6 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.5799999833106995 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.37310636 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |