From Soft Lithography to 3D Printing: Current Status and Future of Microfluidic Device Fabrication Article Swipe
Jingjing Xu
,
Michael Harasek
,
Margit Gfoehler
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/polym17040455
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/polym17040455
The advent of 3D printing has revolutionized the fabrication of microfluidic devices, offering a compelling alternative to traditional soft lithography techniques. This review explores the potential of 3D printing, particularly photopolymerization techniques, fused deposition modeling, and material jetting, in advancing microfluidics. We analyze the advantages of 3D printing in terms of cost efficiency, geometric complexity, and material versatility while addressing key challenges such as material transparency and biocompatibility, which have represented the limiting factors for its widespread adoption. Recent developments in printing technologies and materials are highlighted, underscoring the progress in overcoming these barriers. Finally, we discuss future trends and opportunities, including advancements in printing resolution and speed, the development of new printable materials, process standardization, and the emergence of bioprinting for organ-on-a-chip applications. Sustainability and regulatory frameworks are also considered critical aspects shaping the future of 3D-printed microfluidics. By bridging the gap between traditional and emerging fabrication techniques, this review aims to illuminate the transformative potential of 3D printing in microfluidic device manufacturing.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.3390/polym17040455
- OA Status
- gold
- Cited By
- 26
- References
- 123
- Related Works
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- OpenAlex ID
- https://openalex.org/W4407322369
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4407322369Canonical identifier for this work in OpenAlex
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https://doi.org/10.3390/polym17040455Digital Object Identifier
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From Soft Lithography to 3D Printing: Current Status and Future of Microfluidic Device FabricationWork title
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reviewOpenAlex work type
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enPrimary language
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2025Year of publication
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2025-02-09Full publication date if available
- Authors
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Jingjing Xu, Michael Harasek, Margit GfoehlerList of authors in order
- Landing page
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https://doi.org/10.3390/polym17040455Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.3390/polym17040455Direct OA link when available
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Nanotechnology, Microfluidics, 3D printing, Soft lithography, Lithography, Bridging (networking), Fabrication, Transparency (behavior), Materials science, Computer science, Engineering, Mechanical engineering, Alternative medicine, Pathology, Optoelectronics, Computer security, Medicine, Computer networkTop concepts (fields/topics) attached by OpenAlex
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26Total citation count in OpenAlex
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2025: 26Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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