Neuroscience Applied • Vol 4
Functional connectivity differences in patients with mood disorders: an exploratory fMRI study comparing electroconvulsive therapy with pharmacological treatment
January 2025 • Lydia Fortea, Alexander Tobias Ysbæk-Nielsen, Jeff Zarp Petersen, Patrick M. Fisher, Lars Vedel Kessing, Martin Balslev Jørgensen, Gitte M. Knudsen, …
Electroconvulsive therapy (ECT) has been shown to induce widespread dysregulation of network connectivity in patients with mood disorders. Nevertheless, the extent to which these functional changes contribute to patients’ cognitive side-effects or depressive symptoms improvement remains unclear. This study investigated cross-sectional resting-state functional connectivity (rs-FC) differences in patients with mood disorders after their 8th ECT session (ECT group, n = 33) compared to those receiving pharmacological …