Functional Connectivity Mapping for rTMS Target Selection in Depression Article Swipe
Immanuel Elbau
,
Charles J. Lynch
,
Jonathan Downar
,
Fidel Vila‐Rodriguez
,
Jonathan D. Power
,
Nili Solomonov
,
Zafiris J. Daskalakis
,
Daniel M. Blumberger
,
Conor Liston
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1176/appi.ajp.20220306
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1176/appi.ajp.20220306
Functional connectivity between the sgACC and the stimulated cortex was correlated with individual differences in treatment outcomes, but the association was weaker than those observed in previous studies and was accentuated in a subgroup of patients with distinct, respiration-related signal patterns in their scans. These findings indicate that in a large representative sample of patients with major depressive disorder, individual differences in sgACC-StimFC explained only ∼3% of the variance in outcomes, which may limit the utility of existing sgACC-based targeting protocols. However, these data also provide strong evidence for a true-albeit small-effect and highlight opportunities for incorporating additional functional connectivity measures to generate models of rTMS response with enhanced predictive power.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1176/appi.ajp.20220306
- OA Status
- green
- Cited By
- 91
- References
- 30
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4322719496
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4322719496Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1176/appi.ajp.20220306Digital Object Identifier
- Title
-
Functional Connectivity Mapping for rTMS Target Selection in DepressionWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-03-01Full publication date if available
- Authors
-
Immanuel Elbau, Charles J. Lynch, Jonathan Downar, Fidel Vila‐Rodriguez, Jonathan D. Power, Nili Solomonov, Zafiris J. Daskalakis, Daniel M. Blumberger, Conor ListonList of authors in order
- Landing page
-
https://doi.org/10.1176/appi.ajp.20220306Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
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https://www.ncbi.nlm.nih.gov/pmc/articles/11446248Direct OA link when available
- Concepts
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Anterior cingulate cortex, Functional connectivity, Neuroscience, Transcranial magnetic stimulation, Psychology, Major depressive disorder, Clinical psychology, Cognition, StimulationTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
91Total citation count in OpenAlex
- Citations by year (recent)
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2025: 31, 2024: 39, 2023: 21Per-year citation counts (last 5 years)
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30Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.true-albeit | 90 |
| abstract_inverted_index.connectivity | 1, 99 |
| abstract_inverted_index.sgACC-StimFC | 62 |
| abstract_inverted_index.small-effect | 91 |
| abstract_inverted_index.incorporating | 96 |
| abstract_inverted_index.opportunities | 94 |
| abstract_inverted_index.representative | 51 |
| abstract_inverted_index.respiration-related | 38 |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 99 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 9 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.6000000238418579 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.99740535 |
| citation_normalized_percentile.is_in_top_1_percent | True |
| citation_normalized_percentile.is_in_top_10_percent | True |