American Journal of Psychiatry • Vol 180 • No 3
Functional Connectivity Mapping for rTMS Target Selection in Depression
March 2023 • Immanuel Elbau, Charles J. Lynch, Jonathan Downar, Fidel Vila‐Rodriguez, Jonathan D. Power, Nili Solomonov, Zafiris J. Daskalakis, Daniel M. Blumberg…
Functional connectivity between the sgACC and the stimulated cortex was correlated with individual differences in treatment outcomes, but the association was weaker than those observed in previous studies and was accentuated in a subgroup of patients with distinct, respiration-related signal patterns in their scans. These findings indicate that in a large representative sample of patients with major depressive disorder, individual differences in sgACC-StimFC explained only ∼3% of the variance in outcomes, which ma…