Furosemide and Serum Protein-Bound Uremic Toxin Concentrations in Patients With CKD Article Swipe

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Margaux Costes-Albrespic , Natalia Alencar de Pinho , Islam Amine Larabi , Carolla El Chamieh , Solène M. Laville , Denis Fouque , Maurice Laville , Luc Frimat , Jean‐Claude Alvarez , Ziad Massy , Sophie Liabeuf ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1016/j.ekir.2025.04.040

In patients with CKD, furosemide (particularly at a dose level > 120 mg) is independently associated with higher serum free PBUT concentrations. Our findings suggest that drug-UT competition contributes to PBUT accumulation.

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Furosemide Medicine Kidney disease Toxin Internal medicine Pharmacology Gastroenterology Endocrinology Microbiology Biology

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Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.ekir.2025.04.040
PDF: https://www.kireports.org/action/showPdf?pii=S2468024925002657
OA Status: gold
Cited By: 4
References: 62
Related Works: 10
OpenAlex ID: https://openalex.org/W4410022140

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DOI: https://doi.org/10.1016/j.ekir.2025.04.040

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Title: Furosemide and Serum Protein-Bound Uremic Toxin Concentrations in Patients With CKD

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Type: article

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Language: en

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Publication year: 2025

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Publication date: 2025-05-02

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Authors: Margaux Costes-Albrespic, Natalia Alencar de Pinho, Islam Amine Larabi, Carolla El Chamieh, Solène M. Laville, Denis Fouque, Maurice Laville, Luc Frimat, Jean‐Claude Alvarez, Ziad Massy, Sophie Liabeuf

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Landing page: https://doi.org/10.1016/j.ekir.2025.04.040

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Concepts: Furosemide, Medicine, Kidney disease, Toxin, Internal medicine, Pharmacology, Gastroenterology, Endocrinology, Microbiology, Biology

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Cited by: 4

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