Gender Based Differences in Risks and Comorbidities in Patients Hospitalized with Acute Exacerbation of COPD: A Retrospective Observational study in Eastern-Nepal Article Swipe
Nischit Baral
,
Nabin Raj Karki
,
Prem Parajuli
,
Laura Bell
,
Bidhan Raj Paudel
,
Anish Paudel
,
Nirajan Adhikari
,
Pankaj Luitel
,
Narendra Bhatta
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1101/2021.07.14.21260238
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1101/2021.07.14.21260238
Background Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) share a complex relationship with gender, risk, and co-morbidities. There is paucity of data on the gender-based differences in the prevalence of risks and co-morbidities in AECOPD in Nepal. Methods We performed a retrospective cross-sectional study where data were collected from medical records of adult patients (age >40 years), hospitalized with clinical diagnosis of AECOPD in a tertiary level University hospital in eastern Nepal from April 15, 2014 to October 15, 2014 were included. Data analysis was performed by using SPSS software (Version 26.0, 2020; SPSS Inc., Chicago, IL). Results Of the 256 patients with the primary diagnosis of AECOPD, mean age was 69 years and 65.63% (n=168) of hospitalizations were female population. Compared to males, 64.32 % (n=137) of active smokers were females p= 0.299, 76.19% (n=32) of diabetics were females p= 0.155, 72.86% (n=51) of hypertensive were females, p= 0.143, 50% (n= 6) of underlying Atrial fibrillation were in females p= 0.350, 57.50% (n= 23) of anemics were females p= 0.278, 100% (n= 3) of asthmatics were females p= 0.553, 44.44% (n= 8) of Pulmonary tuberculosis were in females p= 0.070, and 78.76% (n= 89) of indoor air pollution exposure was in females p <0.001. Conclusion Females have higher association to indoor air pollution exposure compared to male and this association was found to be statistically significant. The higher incidence of AECOPD hospitalization in females can be explained by these findings. We need larger studies to validate these findings.
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- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/2021.07.14.21260238
- https://www.medrxiv.org/content/medrxiv/early/2021/07/18/2021.07.14.21260238.full.pdf
- OA Status
- green
- References
- 19
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3186208376
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3186208376Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1101/2021.07.14.21260238Digital Object Identifier
- Title
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Gender Based Differences in Risks and Comorbidities in Patients Hospitalized with Acute Exacerbation of COPD: A Retrospective Observational study in Eastern-NepalWork title
- Type
-
preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-07-18Full publication date if available
- Authors
-
Nischit Baral, Nabin Raj Karki, Prem Parajuli, Laura Bell, Bidhan Raj Paudel, Anish Paudel, Nirajan Adhikari, Pankaj Luitel, Narendra BhattaList of authors in order
- Landing page
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https://doi.org/10.1101/2021.07.14.21260238Publisher landing page
- PDF URL
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https://www.medrxiv.org/content/medrxiv/early/2021/07/18/2021.07.14.21260238.full.pdfDirect link to full text PDF
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://www.medrxiv.org/content/medrxiv/early/2021/07/18/2021.07.14.21260238.full.pdfDirect OA link when available
- Concepts
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Medicine, Exacerbation, COPD, Retrospective cohort study, Internal medicine, Medical record, Atrial fibrillation, Population, Pulmonary disease, Pediatrics, Environmental healthTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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19Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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