Green synthesis of silver nanoparticles from Neurada procumbens and its antibacterial activity against multi-drug resistant microbial pathogens Article Swipe
Fahad A. Al‐Harbi
,
Abdullah A. Alarfaj
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1016/j.jksus.2019.11.026
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1016/j.jksus.2019.11.026
The aim of this work was to develop a new biological process for the fabrication of silver nanoparticles (Ag-NPs) using the extract of a xerophytic plant (Neurada procumbens) as a reducing agent. The fabricated Ag-NPs can effectively control multi-drug resistant gram-negative rods (MDR-GNRs), which were isolated from the Buraidah Central Hospital (BCH), Saudi Arabia. The predominant MDR-GNR bacteria included Klebsiella pneumoniae, Acinetobacter baumannii, and Escherichia coli. The Ag-NPs were examined by diverse spectral and analytical techniques, and then their antibacterial effects against MDR bacteria were determined. The UV spectroscopy showed absorption peaks between 400 and 455 nm specific to AgNPs. The SEM and TEM results showed a smallsize of Ag-NPs in a range of about 20–50 nm. The XRD pattern showed three major distinctive peaks of Ag-NPs at 38.1°, 44.3° and 64.4° confirming the presence of Ag-NPs. Three multidrug-resistant bacterial strains were used to determine antimicrobial activity by the well-diffusion method. The present workillusrates that synthesized Ag-NPs from the aqueous leaf extract of Neurada procumbens show considerable antibacterial potential against MDR clinical isolates from different patient samples at BCH. Keywords: Silver, Nanoparticle, Antibacterial, MDR bacteria, Clinical isolates
Related Topics
Concepts
Acinetobacter baumannii
Antibacterial activity
Antimicrobial
Klebsiella pneumoniae
Silver nanoparticle
Multiple drug resistance
Bacteria
Nuclear chemistry
Multi drug resistant
Escherichia coli
Agar diffusion test
Chemistry
Microbiology
Materials science
Antibiotics
Nanoparticle
Nanotechnology
Biology
Biochemistry
Gene
Pseudomonas aeruginosa
Genetics
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.jksus.2019.11.026
- OA Status
- gold
- Cited By
- 52
- References
- 40
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2990718423
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2990718423Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.jksus.2019.11.026Digital Object Identifier
- Title
-
Green synthesis of silver nanoparticles from Neurada procumbens and its antibacterial activity against multi-drug resistant microbial pathogensWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-11-27Full publication date if available
- Authors
-
Fahad A. Al‐Harbi, Abdullah A. AlarfajList of authors in order
- Landing page
-
https://doi.org/10.1016/j.jksus.2019.11.026Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1016/j.jksus.2019.11.026Direct OA link when available
- Concepts
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Acinetobacter baumannii, Antibacterial activity, Antimicrobial, Klebsiella pneumoniae, Silver nanoparticle, Multiple drug resistance, Bacteria, Nuclear chemistry, Multi drug resistant, Escherichia coli, Agar diffusion test, Chemistry, Microbiology, Materials science, Antibiotics, Nanoparticle, Nanotechnology, Biology, Biochemistry, Gene, Pseudomonas aeruginosa, GeneticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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52Total citation count in OpenAlex
- Citations by year (recent)
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2025: 3, 2024: 9, 2023: 12, 2022: 4, 2021: 18Per-year citation counts (last 5 years)
- References (count)
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40Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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