Gut Microbiome and Hepatic Transcriptomic Determinants of HCC Development in Mice with Metabolic Dysfunction-Associated Steatohepatitis Article Swipe
Lillian I. Dolapchiev
,
Kristyn Gonzales
,
Lorenzo R. Cruz
,
Mihai Gagea
,
Heather L. Stevenson
,
Suet‐Ying Kwan
,
Laura Beretta
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.2147/jhc.s485532
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.2147/jhc.s485532
We identified microbiome components contributing to liver carcinogenesis by inducing inflammation, and changes in hepatic gene expression and hepatic cells distribution that contribute to tumor growth. Such information can be highly valuable for the development of new prevention strategies as well as of new biomarkers for risk modeling in HCC.
Related Topics
Concepts
Steatohepatitis
Gut microbiome
Transcriptome
Microbiome
Biology
Immunology
Fatty liver
Medicine
Bioinformatics
Internal medicine
Disease
Biochemistry
Gene
Gene expression
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.2147/jhc.s485532
- OA Status
- gold
- Cited By
- 2
- References
- 66
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4403109879
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4403109879Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.2147/jhc.s485532Digital Object Identifier
- Title
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Gut Microbiome and Hepatic Transcriptomic Determinants of HCC Development in Mice with Metabolic Dysfunction-Associated SteatohepatitisWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-10-01Full publication date if available
- Authors
-
Lillian I. Dolapchiev, Kristyn Gonzales, Lorenzo R. Cruz, Mihai Gagea, Heather L. Stevenson, Suet‐Ying Kwan, Laura BerettaList of authors in order
- Landing page
-
https://doi.org/10.2147/jhc.s485532Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.2147/jhc.s485532Direct OA link when available
- Concepts
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Steatohepatitis, Gut microbiome, Transcriptome, Microbiome, Biology, Immunology, Fatty liver, Medicine, Bioinformatics, Internal medicine, Disease, Biochemistry, Gene, Gene expressionTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
- Citations by year (recent)
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2025: 2Per-year citation counts (last 5 years)
- References (count)
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66Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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