Health profiles of foreign-born elderly women with HIV in Italy Article Swipe
Stefania Arsuffi
,
Eugenia Quiros-Roldan
,
Francesca Colombo
,
Bernard Fioretti
,
Caterina Candela
,
Benedetto Maurizio Celesia
,
Sergio Ferrara
,
Jovana Milić
,
Giuseppe Vittorio De Socio
,
Giordano Maddeddu
,
Anna Maria Cattelan
,
Stefania Piconi
,
Paolo Bonfanti
,
Agostino Riva
,
Giovanni Guaraldi
,
Stefano Calza
,
Andrea Calcagno
,
Emanuele Focà
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fragi.2025.1659751
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fragi.2025.1659751
Background Ageing trajectories for foreign-born individuals and women living with HIV remain poorly defined globally. This study aimed to characterize foreign-born women living with HIV aged ≥65 years (FWLH) and compare them to age-matched Italian women (IWLH) and foreign-born men living with HIV (FMLH). Methods Data were drawn from the multicenter Italian geriatric HIV cohort (GEPPO). We described sociodemographic characteristics, viro-immunological status, comorbidities, and multidimensional geriatric assessment in FWLH. A complete case analysis was supplemented by multiple imputation using the mice package with the Predictive Mean Matching (PMM) method, and pooled estimates were derived from regression models, that included an interaction term for sex × birthplace. Results We included 330 participants: 285 (86.5%) women, 15 (4.5%) FWLH and 30 (9%) FMLH. Comparing FWLH to IWLH, lower CD4+/CD8+ ratio (beta −0.38; 95% confidence interval (CI) −0.79, 0.03; p-value = 0.069) and percentage of CD4 + cell (beta −10; 95% CI -16, −4.1; p-value = 0.001) and higher weight (beta 11; 95% CI 3.4, 18; p-value = 0.004) and BMI (beta 3.8; 95% CI 0.57, 7.0; p-value = 0.021) were observed. Comparing FMLH to FWLH, we found lower prevalence of multimorbidity (IRR 0.60, 95% CI 0.37, 0.98, p-value = 0.039) and osteoporosis, though risk difference for osteoporosis was not significant. In the interaction model, FWLH had a lower percentage of CD4 + cells (β = −0.38; 95% CI: −0.73, −0.02; p = 0.036). Conclusion FWLH in a geriatric cohort showed a profile of immune imbalance and higher weight, BMI, and multimorbidity; this may be possibly related to a worse metabolic profile and poorer access to care. However, there was no difference in virological response and antiretroviral therapies. Enhancing our understanding of older FWLH is crucial for promoting person-centered care a patient-centred care and healthy ageing in this population.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fragi.2025.1659751
- https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2025.1659751/pdf
- OA Status
- gold
- References
- 15
- OpenAlex ID
- https://openalex.org/W4414614706
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4414614706Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fragi.2025.1659751Digital Object Identifier
- Title
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Health profiles of foreign-born elderly women with HIV in ItalyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
-
2025-09-29Full publication date if available
- Authors
-
Stefania Arsuffi, Eugenia Quiros-Roldan, Francesca Colombo, Bernard Fioretti, Caterina Candela, Benedetto Maurizio Celesia, Sergio Ferrara, Jovana Milić, Giuseppe Vittorio De Socio, Giordano Maddeddu, Anna Maria Cattelan, Stefania Piconi, Paolo Bonfanti, Agostino Riva, Giovanni Guaraldi, Stefano Calza, Andrea Calcagno, Emanuele FocàList of authors in order
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https://doi.org/10.3389/fragi.2025.1659751Publisher landing page
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https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2025.1659751/pdfDirect link to full text PDF
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YesWhether a free full text is available
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-
goldOpen access status per OpenAlex
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https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2025.1659751/pdfDirect OA link when available
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0Total citation count in OpenAlex
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15Number of works referenced by this work
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| institutions_distinct_count | 18 |
| citation_normalized_percentile.value | 0.61128737 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |