Heart Transplantation for Peripartum Cardiomyopathy: A Single-Center Experience Article Swipe
Nadia Bouabdallaoui
,
Pierre Demondion
,
Sylvestre Maréchaux
,
Shaïda Varnous
,
Guillaume Lebreton
,
Frédéric Mouquet
,
Pascal Leprince
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.6084/m9.figshare.5907706
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.6084/m9.figshare.5907706
Background: Peripartum cardiomyopathy is an idiopathic disorder defined by the occurrence of acute heart failure during late pregnancy or post-partum period in the absence of any other definable cause. Its clinical course is variable and severe cases might require heart transplantation. Objective: To investigate long-term outcomes after heart transplantation (HT) for peripartum cardiomyopathy (PPCM). Methods: Out of a single-center series of 1938 HT, 14 HT were performed for PPCM. We evaluated clinical characteristics, transplant-related complications, and long-term outcomes, in comparison with 28 sex-matched controls. Primary endpoint was death from any cause; secondary endpoints were transplant-related complications (rejection, infection, cardiac allograft vasculopathy). A value of p < 0.05 was considered of statistical significance. Results: PPCM patients and matched controls were comparable for most variables (all p values > 0.05), except for a higher use of inotropes at the time of HT in PPCM group (p = 0.03). During a median follow-up of 7.7 years, 16 patients died, 3 (21.5%) in PPCM group and 13 (46.5%) in control group. Mortality was significantly lower in PPCM group (p = 0.03). No significant difference was found in terms of transplant-related complications (p > 0.05). Conclusions: Long-term outcomes following HT for PPCM are favorable. Heart transplantation is a valuable option for PPCM patients who did not recover significantly under medical treatment.
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- en
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- OA Status
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https://openalex.org/W4394319857Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.6084/m9.figshare.5907706Digital Object Identifier
- Title
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Heart Transplantation for Peripartum Cardiomyopathy: A Single-Center ExperienceWork title
- Type
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datasetOpenAlex work type
- Language
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enPrimary language
- Publication year
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2018Year of publication
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2018-01-01Full publication date if available
- Authors
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Nadia Bouabdallaoui, Pierre Demondion, Sylvestre Maréchaux, Shaïda Varnous, Guillaume Lebreton, Frédéric Mouquet, Pascal LeprinceList of authors in order
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https://doi.org/10.6084/m9.figshare.5907706Publisher landing page
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.6084/m9.figshare.5907706Direct OA link when available
- Concepts
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Peripartum cardiomyopathy, Heart transplantation, Medicine, Cardiology, Transplantation, Center (category theory), Cardiomyopathy, Single Center, Internal medicine, Heart failure, Chemistry, CrystallographyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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