Hepatitis C Screening and Treatment Program in Hungarian Prisons in the Era of Direct Acting Antiviral Agents Article Swipe
Klára Werling
,
Béla Hunyady
,
Mihály Makara
,
Krisztina Nemesi
,
Gábor Horváth
,
Ferenc Schneider
,
Judit Enyedi
,
Zsófia Müller
,
Miklós Lesch
,
Zoltán Péterfi
,
T Tóth
,
Judit Gács
,
Zsuzsanna Fehér
,
Eszter Ujhelyi
,
Emese Ilyésné Molnár
,
Anna Nagy
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/v14020308
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/v14020308
A hepatitis C virus (HCV) screening and treatment program was conducted in Hungarian prisons on a voluntary basis. After HCV-RNA testing and genotyping for anti-HCV positives, treatments with direct-acting antiviral agents were commenced by hepatologists who visited the institutions monthly. Patients were supervised by the prisons’ medical staff. Data were retrospectively collected from the Hungarian Hepatitis Treatment Registry, from the Health Registry of Prisons, and from participating hepatologists. Eighty-four percent of Hungarian prisons participated, meaning a total of 5779 individuals (28% of the inmate population) underwent screening. HCV-RNA positivity was confirmed in 317/5779 cases (5.49%); 261/317 (82.3%) started treatment. Ninety-nine percent of them admitted previous intravenous drug use. So far, 220 patients received full treatment and 41 patients are still on treatment. Based on the available end of treatment (EOT) + 24 weeks timepoint data, per protocol sustained virologic response rate was 96.8%. In conclusion, the Hungarian prison screening and treatment program, with the active participation of hepatologists and the prisons’ medical staff, is a well-functioning model. Through the Hungarian experience, we emphasize that the “test-and-treat” principle is feasible and effective at micro-eliminating HCV in prisons, where infection rate, as well as history of intravenous drug usage, are high.
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Metadata
- Type
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- Language
- en
- Landing Page
- https://doi.org/10.3390/v14020308
- https://www.mdpi.com/1999-4915/14/2/308/pdf?version=1644476590
- OA Status
- gold
- Cited By
- 11
- References
- 32
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4210591218
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4210591218Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/v14020308Digital Object Identifier
- Title
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Hepatitis C Screening and Treatment Program in Hungarian Prisons in the Era of Direct Acting Antiviral AgentsWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-02-02Full publication date if available
- Authors
-
Klára Werling, Béla Hunyady, Mihály Makara, Krisztina Nemesi, Gábor Horváth, Ferenc Schneider, Judit Enyedi, Zsófia Müller, Miklós Lesch, Zoltán Péterfi, T Tóth, Judit Gács, Zsuzsanna Fehér, Eszter Ujhelyi, Emese Ilyésné Molnár, Anna NagyList of authors in order
- Landing page
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https://doi.org/10.3390/v14020308Publisher landing page
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https://www.mdpi.com/1999-4915/14/2/308/pdf?version=1644476590Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/1999-4915/14/2/308/pdf?version=1644476590Direct OA link when available
- Concepts
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Virology, Medicine, Antiviral treatment, Hepatitis C, Hepatitis, Family medicine, Chronic hepatitis, VirusTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
11Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3, 2024: 4, 2023: 3, 2022: 1Per-year citation counts (last 5 years)
- References (count)
-
32Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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