High sensitive optical-chemical sensors based on optical fibers in a reflection scheme combined with C-shaped waveguides of MIP-microbeads Article Swipe
Rosalba Pitruzzella
,
Filipa Sequeira
,
Alessandra Cutaia
,
Chiara Marzano
,
Francesco Arcadio
,
Catarina Cardoso Novo
,
Ricardo Oliveira
,
Maria Pesavento
,
Luigi Zeni
,
Giancarla Alberti
,
Rogério N. Nogueira
,
Nunzio Cennamo
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.talanta.2025.128647
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.talanta.2025.128647
In order to monitor analytes in liquid matrices, optical fiber probes in reflection mode can be exploited in several application fields. This work presents a novel sensing approach based on C-shaped waveguides obtained by filling PVC C-shaped channels with microbeads of molecularly imprinted polymers (MIP-microbeads). Specifically, for the first time, MIP microbeads are used as a sensitive core of optical waveguides with several advantages. The MIP microbeads C-shaped waveguide is in contact with a polished plastic optical fiber (POF) at one end to connect the sensitive region with the light source and the detector in a reflection-based scheme via a simple POF-based splitter. As a proof of concept, the MIP-microbeads were prepared using 2-furaldehyde (2-FAL) as the template to compare the results with other optical fiber sensors. Moreover, to highlight the performance improvement of the proposed sensing approach compared to MIP-based configurations, a sensor based on an MIP (MIP-mass sensor) instead of MIP-microbeads has been developed, tested, and compared with the MIP-microbeads sensor and the state-of-the-art. The results obtained via the MIP-microbeads sensor demonstrated the best performance, with an ultra-low detection limit at a pico-nano molar level and an ultra-wide detection concentration range of about four orders of magnitude. Moreover, the proposed optical-chemical sensor probe is small-size (at a micron scale), simple to realize, low-cost, mechanically robust, suitable for installation even in extreme conditions, and can be used in a real scenario where a reflection scheme sensor is required. An experimental test in the food application field is reported.
Related Topics
Concepts
Optical fiber
Fiber optic sensor
Molecularly imprinted polymer
Waveguide
Splitter
Chemistry
Detection limit
Reflection (computer programming)
Optoelectronics
Analyte
Nanotechnology
Optics
Materials science
Chromatography
Computer science
Biochemistry
Selectivity
Catalysis
Physics
Programming language
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.talanta.2025.128647
- OA Status
- hybrid
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4412686774
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4412686774Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.talanta.2025.128647Digital Object Identifier
- Title
-
High sensitive optical-chemical sensors based on optical fibers in a reflection scheme combined with C-shaped waveguides of MIP-microbeadsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-07-28Full publication date if available
- Authors
-
Rosalba Pitruzzella, Filipa Sequeira, Alessandra Cutaia, Chiara Marzano, Francesco Arcadio, Catarina Cardoso Novo, Ricardo Oliveira, Maria Pesavento, Luigi Zeni, Giancarla Alberti, Rogério N. Nogueira, Nunzio CennamoList of authors in order
- Landing page
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https://doi.org/10.1016/j.talanta.2025.128647Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1016/j.talanta.2025.128647Direct OA link when available
- Concepts
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Optical fiber, Fiber optic sensor, Molecularly imprinted polymer, Waveguide, Splitter, Chemistry, Detection limit, Reflection (computer programming), Optoelectronics, Analyte, Nanotechnology, Optics, Materials science, Chromatography, Computer science, Biochemistry, Selectivity, Catalysis, Physics, Programming languageTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
46Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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