High-sensitivity troponin T and I in patients suspected of acute myocardial infarction Article Swipe
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· 2022
· Open Access
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· DOI: https://doi.org/10.1080/00365513.2022.2033310
Measurement of cardiac troponin (cTn) is the cornerstone in the diagnosis of myocardial infarction (MI). Potential disparities in concentrations of cTn, trajectories and mortality, following initial measurement warrant further investigation. Such data may guide clinicians treating patients suspected of MI. Plasma concentrations of cTnT and cTnI were measured in 503 consecutive patients at Aarhus University Hospital between June 13th and June 27th, 2019. cTnT was measured with the Roche cobas® E602 hs-cTnT assay, while cTnI was measured with the Siemens ADVIA Centaur® XPT hs-cTnI assay. Analytical agreement was determined based on assay-specific 99th percentiles. Medical records were reviewed for adjudication of the MI diagnosis. MI was the final diagnosis in 65 patients (12.9%) and the analytical agreement between cTnT and cTnI assays was 95.2%. For patients diagnosed with MI, cTnI reached higher peak concentrations in shorter time, compared to cTnT. All-cause mortality risk increased with increasing levels of both biomarkers. In this study, the analytical agreement of two cTn assays was high. However, some disparities in troponin trajectories were observed.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1080/00365513.2022.2033310
- OA Status
- green
- Cited By
- 5
- References
- 17
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4221043038
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4221043038Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1080/00365513.2022.2033310Digital Object Identifier
- Title
-
High-sensitivity troponin T and I in patients suspected of acute myocardial infarctionWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-03-06Full publication date if available
- Authors
-
Steffan Kleemeier, Anders Abildgaard, Søren Ladefoged, Jacob Thorsted Sørensen, Carsten Stengaard, Kasper AdelborgList of authors in order
- Landing page
-
https://doi.org/10.1080/00365513.2022.2033310Publisher landing page
- Open access
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
- OA URL
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https://figshare.com/articles/journal_contribution/High-sensitivity_troponin_T_and_I_in_patients_suspected_of_acute_myocardial_infarction/19314107Direct OA link when available
- Concepts
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Medicine, Myocardial infarction, Troponin I, Internal medicine, Cardiology, Roche Diagnostics, Troponin complex, Troponin, Myocardial infarction diagnosisTop concepts (fields/topics) attached by OpenAlex
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5Total citation count in OpenAlex
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2025: 1, 2024: 2, 2023: 1, 2022: 1Per-year citation counts (last 5 years)
- References (count)
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17Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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